公开(公告)号：US20190217613A1

公开(公告)日：2019-07-18

申请号：US16306607

申请日：2016-09-26

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Zhizhang Chen ,  Mohammed S Shaarawi ,  Jeremy Sells

IPC: B41J2/14 ,  B41J2/16 ,  C23C16/455

CPC classification number: B41J2/14129 ,  B41J2/1601 ,  B41J2/1629 ,  B41J2/1642 ,  B41J2/1646 ,  B41J2202/11 ,  C23C4/04 ,  C23C4/134 ,  C23C16/45536

Abstract: A thin film stack can include a metal substrate having a thickness of from 200 angstroms to 5000 angstroms and a passivation barrier disposed on the metal substrate at a thickness of from 600 angstroms to 1650 angstroms. The passivation barrier can include a dielectric layer and an atomic layer deposition (ALD) layer disposed on the dielectric layer. The dielectric layer can have a thickness of from 550 to 950 angstroms. The ALD layer can have a thickness from 50 to 700 angstroms.

公开(公告)号：US11486839B2

公开(公告)日：2022-11-01

申请号：US15300698

申请日：2014-04-25

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Nicholas Matthew Cooper McGuinness ,  Manish Giri ,  Chantelle Elizabeth Domingue ,  Melinda M. Valencia ,  Jeremy Sells

IPC: G01N27/02 ,  B01L3/00 ,  A61B5/145 ,  A61B5/1477 ,  A61B5/00

Abstract: A diagnostic cassette includes a substrate, to physically and electrically connect the product to a computing device, a reservoir defined within the substrate to receive a fluid sample for processing by the diagnostic cassette, a reagent to react with the fluid sample deposited in the reservoir to form a solution to enable processing of the fluid sample by the diagnostic cassette, a channel to direct the solution, and a sensor to measure a number of parameters of the solution passing through the channel. A method for measuring microfluidic samples includes receiving, in a reservoir, a fluid sample to be measured, combining the fluid sample with a reagent to create a solution, moving the solution through a channel, and measuring the solution, using sensors, as the solution passes through the channel.

公开(公告)号：US11366051B2

公开(公告)日：2022-06-21

申请号：US15546342

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Jeremy Sells ,  Nick McGuinness ,  Chantelle Domingue ,  Manish Giri

IPC: G01N15/10 ,  B01L3/00

Abstract: A device including a microfluidic channel structure formed on a substrate and including a first channel and a fluid actuator within the microfluidic channel structure. A sense region within the first channel is to receive a fluid flow of target biologic particles for counting in a single file pattern, with the sense region having a volume on a same order of magnitude as a volume of a single one of the target biologic particles.

公开(公告)号：US11097268B2

公开(公告)日：2021-08-24

申请号：US15546352

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Jeremy Sells ,  Nick McGuinness ,  Chantelle Domingue ,  Manish Giri

IPC: B01L3/00

Abstract: A device includes a microfluidic channel structure on a substrate with a first fluid actuator and a second fluid actuator within the microfluidic channel structure. One of the fluid actuators is selectively employable to at least partially reverse fluid flow within at least a portion of the microfluidic channel structure in response to a blockage or to prevent a blockage.

公开(公告)号：US10894406B2

公开(公告)日：2021-01-19

申请号：US16306607

申请日：2016-09-26

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Zhizhang Chen ,  Mohammed S Shaarawi ,  Jeremy Sells

IPC: B41J2/14 ,  B41J2/16 ,  C23C4/134 ,  C23C4/04 ,  C23C16/455

Abstract: A thin film stack can include a metal substrate having a thickness of from 200 angstroms to 5000 angstroms and a passivation barrier disposed on the metal substrate at a thickness of from 600 angstroms to 1650 angstroms. The passivation barrier can include a dielectric layer and an atomic layer deposition (ALD) layer disposed on the dielectric layer. The dielectric layer can have a thickness of from 550 to 950 angstroms. The ALD layer can have a thickness from 50 to 700 angstroms.

公开(公告)号：US10427406B2

公开(公告)日：2019-10-01

申请号：US15772344

申请日：2016-02-05

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Garrett E. Clark ,  Michael W. Cumbie ,  Jeremy Sells ,  Mark H. MacKenzie

IPC: B41J2/155 ,  B41J29/38 ,  B41J29/393 ,  B41J2/14 ,  B41J11/00 ,  B41J13/32 ,  B41J2/21

Abstract: The present disclosure includes a description of an example print bar that includes an ejection die disposed on a support element, and a sensor disposed at a particular location on the support element.

公开(公告)号：US10399079B2

公开(公告)日：2019-09-03

申请号：US15546735

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Nicholas McGuinness ,  Chantelle Domingue ,  Manish Giri ,  Jeremy Sells

IPC: B01L3/00 ,  G01N27/07 ,  G01N33/487

Abstract: A microfluidic diagnostic device may comprise a fluid inlet to receive a fluid from a fluidic slot, a main microfluidic channel fluidly coupled to the fluid inlet, and a main microfluidic pump interposed between the fluid inlet and the main microfluidic channel to continuously circulate a fluid through the fluidic slot, fluid inlet, and main microfluidic channel wherein the width of the fluid inlet is different from the width of the main microfluidic channel. A diagnostic device, comprising a fluidic slot, a fluid inlet fluidly coupled to the fluidic slot, a main channel fluidly coupled to the fluid inlet, and an inlet pump interposed between the fluid inlet and channel wherein the cross-sectional area of the fluid inlet is relatively larger at least one point than the cross-sectional area of the channel.

公开(公告)号：US12023937B2

公开(公告)日：2024-07-02

申请号：US17798902

申请日：2020-03-11

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Jacob M. Lum ,  Si-lam J. Choy ,  Jeffrey R. Pollard ,  Tsuyoshi Yamashita ,  Jeremy Sells ,  Garrett E. Clark

IPC: B41J2/18 ,  B41J2/14

CPC classification number: B41J2/18 ,  B41J2/1408

Abstract: A fluid ejection die may include a fluid actuator, a substrate supporting the fluid actuator, a chamber layer supported by the substrate and a bypass passage in the substrate. The substrate may include a closed inlet channel having an inlet opening for connection to an outlet of a fluid source and an outlet channel having an outlet opening of a first size for connection to an inlet of the fluid source. The chamber layer includes a recirculation passage to supply fluid for ejection by the fluid actuator through an ejection orifice and to circulate fluid across the fluid actuator from the closed inlet channel to the outlet channel. The bypass passage is of a second size less than the first size and connects the inlet channel to the inlet of the fluid source while bypassing any fluid actuator provided for ejecting fluid through an ejection orifice.

公开(公告)号：US10953397B2

公开(公告)日：2021-03-23

申请号：US15546498

申请日：2015-01-30

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Melinda M. Valencia ,  Sirena Lu ,  Chantelle Elizabeth Domingue ,  Jeremy Sells

IPC: G01N27/02 ,  B01L3/00 ,  G01N33/487 ,  H02M3/155

Abstract: A system may comprise a voltage upconverter, a universal serial bus (USB) connector to receive an input voltage from a USB port on a computing device, and a microfluidic diagnostic chip communication link to electrically couple the voltage upconverter to a microfluidic diagnostic chip wherein the voltage upconverter is to convert the input voltage to be received by the USB connector to an output voltage sufficient to drive a pump on the microfluidic diagnostic chip. A diagnostic system may comprise a microfluidic diagnostic chip comprising a pump and a voltage upconverter to receive an input voltage from a universal serial bus (USB) port of a computing device and to convert the input voltage into an output voltage that powers activation of the pump.

公开(公告)号：US10913066B2

公开(公告)日：2021-02-09

申请号：US15546511

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Manish Giri ,  Chantelle Elizabeth Domingue ,  Nicholas Matthew Cooper McGuinness ,  Jeremy Sells ,  Sirena Lu ,  Melinda M. Valencia

IPC: B01L99/00 ,  B01L3/00 ,  G01N33/543 ,  G01N15/06 ,  C12Q1/6804 ,  C12Q1/00 ,  G01N15/00

Abstract: A microfluidic diagnostic chip may comprise a microfluidic channel, a functionalizable enzymatic sensor in the microfluidic channel, the functionalizable enzymatic sensor comprising a binding surface to bind with a biomarker in a fluid, and a microfluidic pump to pass the fluid over the binding surface. A microfluidic device may comprise a number of pumps to pump a fluid though the number of microfluidic channels and a number of microfluidic channels comprising at least one sensor to detect a change in a chemical characteristic of the fluid in response to presence of the fluid on the sensor.