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公开(公告)号:US10725019B2
公开(公告)日:2020-07-28
申请号:US15522831
申请日:2015-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Melinda M Valencia , Chantelle E Domingue , Jeremy Sells , Manish Giri , Sadiq Bengali
Abstract: Example implementations relate to coagulation sensing. For example, a microfluidic chip for coagulation sensing may include a microfluidic channel, an outlet at an end of the microfluidic channel having an air interface, and an impedance sensor located within the microfluidic channel and within a particular proximity to the air interface, the impedance sensor to determine a stage of a coagulation cascade of a blood sample flowing through the microfluidic channel to the impedance sensor.
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公开(公告)号:US20180011042A1
公开(公告)日:2018-01-11
申请号:US15545406
申请日:2015-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Jeremy Sells , Chantelle E. Domingue , Manish Giri , Melinda M. Valencia
CPC classification number: G01N27/06 , B01L3/502715 , B01L2200/0652 , B01L2300/023 , B01L2300/0645 , G01N15/1031 , G01N15/1056 , G01N2015/0065 , G01N2015/1006
Abstract: A method of microfluidic detection can include detecting, using an impedance sensor, an impedance of a fluid to indicate whether a threshold amount of fluid has been received in a reservoir of a microfluidic chip. The method can include initiating a test performed by the microfluidic chip on the received fluid when the threshold amount of fluid has been received.
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公开(公告)号:US09849673B2
公开(公告)日:2017-12-26
申请号:US15128219
申请日:2014-04-11
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Nicholas Matthew Cooper McGuinness , Manish Giri , Chantelle Elizabeth Domingue , Melinda M. Valencia , Jeremy Sells
IPC: B41J2/14
CPC classification number: B41J2/14314 , B41J2/135 , B41J2/14 , B41J2/1404 , B41J2/14096 , B41J2/1433
Abstract: A printhead includes a plurality of firing chambers, a plurality of fluid ejectors, and at least one field generating member. Each one of the firing chambers includes a nozzle region to receive printing fluid. The printing fluid includes an ink vehicle having pigments disposed therein. At least one field generating member generates a non-uniform electric field to apply forces to maintain respective pigments in the ink vehicle of the printing fluid in the nozzle region.
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公开(公告)号:US20170108455A1
公开(公告)日:2017-04-20
申请号:US15300698
申请日:2014-04-25
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Nicholas Matthew Cooper McGuinness , Manish Giri , Chantelle Elizabeth Domingue , Melinda M. Valencia , Jeremy Sells
CPC classification number: G01N27/02 , A61B5/14507 , A61B5/14546 , A61B5/1477 , A61B5/41 , A61B2503/42 , A61B2560/0456 , A61B2560/0462 , A61B2562/028 , B01L3/502715 , B01L3/502761 , B01L2200/0652 , B01L2200/16 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2400/0487
Abstract: A diagnostic cassette includes a substrate, to physically and electrically connect the product to a computing device, a reservoir defined within the substrate to receive a fluid sample for processing by the diagnostic cassette, a reagent to react with the fluid sample deposited in the reservoir to form a solution to enable processing of the fluid sample by the diagnostic cassette, a channel to direct the solution, and a sensor to measure a number of parameters of the solution passing through the channel. A method for measuring microfluidic samples includes receiving, in a reservoir, a fluid sample to be measured, combining the fluid sample with a reagent to create a solution, moving the solution through a channel, and measuring the solution, using sensors, as the solution passes through the channel.
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公开(公告)号:US11590495B2
公开(公告)日:2023-02-28
申请号:US16619508
申请日:2017-07-28
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Hilary Ely , Matthew David Smith , Jeremy Sells , George H. Corrigan , Michael W. Cumbie , Chantelle Domingue
IPC: C12Q1/6876 , B01L3/00 , B01L7/00 , G01N21/64
Abstract: A method may include maintaining a sample comprising an ionic species and an optical indicator at an elevated temperature above 25° C. on a semi-conductive microfluidic die during an incubation period, intermittently interrogating the sample with an interrogating light during the incubation period and sensing a response of the sample to the interrogating light, wherein the sample is interrogated with the interrogating light only during those times at which the sample is being sensed.
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公开(公告)号:US11325385B2
公开(公告)日:2022-05-10
申请号:US16640563
申请日:2017-10-19
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Jacob Lum , Jeremy Sells , Si-lam Choy
Abstract: A fluidic die may include a fluid channel layer defining a number of fluid channels therein, a slot layer disposed on a side of the fluid channel layer, and a first fluid slot and a second fluid slot defined in the slot layer. At least one of the fluid channels fluidically couples the first fluid slot to the second fluid slot. The first fluid slot and the second fluid slot are defined in the slot layer along a length of the fluidic die.
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公开(公告)号:US11179720B2
公开(公告)日:2021-11-23
申请号:US16319702
申请日:2016-10-07
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Manish Giri , Chantelle Domingue , Tod Woodford , Matthew David Smith , Rachel M. White , Joshua M. Yu , Hilary Ely , Jeremy Sells
Abstract: The present disclosure is drawn to microfluidic chips. The microfluidic chips can include an inflexible material having an elastic modulus of 0.1 gigapascals (GPa) to 450 GPa. A microfluidic channel can be formed within the inflexible material and can connect an inlet and an outlet. A working electrode can be associated with the microfluidic channel and can have a surface area of 1 μm2 to 60,000 μm2 within the microfluidic channel. A bubble support structure can also be formed within the microfluidic channel such that the working electrode is positioned to electrolytically generate a bubble that becomes associated with the bubble support structure.
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公开(公告)号:US11035814B2
公开(公告)日:2021-06-15
申请号:US15545406
申请日:2015-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Jeremy Sells , Chantelle E. Domingue , Manish Giri , Melinda M. Valencia
Abstract: A method of microfluidic detection can include detecting, using an impedance sensor, an impedance of a fluid to indicate whether a threshold amount of fluid has been received in a reservoir of a microfluidic chip. The method can include initiating a test performed by the microfluidic chip on the received fluid when the threshold amount of fluid has been received.
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公开(公告)号:US20210114032A1
公开(公告)日:2021-04-22
申请号:US17044404
申请日:2018-04-23
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Garrett E. Clark , Si-lam Choy , Jacob Lum , Craig Olbrich , Jeremy Sells , Tsuyoshi Yamashita
IPC: B01L3/00
Abstract: A fluidic die may include a at least one actuator, and fluid flow architecture to flow a first fluid through at least one fluidic channel, and flow a second fluid through the at least one fluidic channel to form a laminar flow between the first fluid and the actuator. The at least one actuator forms a drive bubble from the second fluid to cause the first fluid to be ejected from the fluidic die.
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公开(公告)号:US20200238708A1
公开(公告)日:2020-07-30
申请号:US16640563
申请日:2017-10-19
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Jacob Lum , Jeremy Sells , Si-lam Choy
Abstract: A fluidic die may include a fluid channel layer defining a number of fluid channels therein, a slot layer disposed on a side of the fluid channel layer, and a first fluid slot and a second fluid slot defined in the slot layer. At least one of the fluid channels fluidically couples the first fluid slot to the second fluid slot. The first fluid slot and the second fluid slot are defined in the slot layer along a length of the fluidic die.
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