Blood fractionation method
    12.
    发明授权
    Blood fractionation method 失效
    血液分离法

    公开(公告)号:US5783085A

    公开(公告)日:1998-07-21

    申请号:US655292

    申请日:1996-05-15

    Inventor: Halbert Fischel

    Abstract: A system for separating at least one constituent from a liquid suspension such as blood induces high velocity flow by viscous drag about the circumference of a spinner having a filtration membrane with pore sized selected for the desired constituent. The high velocity circumferential flow is bounded by a spaced apart shear wall, with a spacing selected relative to the diameter of the spinner and its rotational velocity, also with respect to the viscosity of the suspension, to establish a flow within the shear gap, as substantial centrifugal forces are exerted upon the suspension. Under these conditions, in contact with the membrane and filtrate passes through the membrane is replenished with minimal adverse effects from deposition and concentration polarization, and with high efficiency because of high shear levels that are maintained. The filtrate is collected within the interior of the spinner in a conduit system and passed to an outlet orifice.

    Abstract translation: 用于从液体悬浮液(例如血液)分离至少一种组分的系统通过围绕具有筛孔的旋转器圆周的粘性阻力引起高速流动,所述过滤膜的孔径选择为所需组分。 高速圆周流动由间隔开的剪切壁界定,相对于旋转器的直径选择相对于悬架的直径的旋转速度的间隔,以便在剪切间隙内建立流动,如 大量的离心力施加在悬架上。 在这些条件下,与膜接触并通过膜的滤液以沉积和浓缩极化的最小不利影响被补充,并且由于维持的高剪切水平而以高效率补充。 滤液在导管系统内收集在旋转器的内部,并通过出口孔。

    Blood leak detector comparing intensities of high absorption band and
low absorption band of a single beam of light passing through a sample
    13.
    发明授权
    Blood leak detector comparing intensities of high absorption band and low absorption band of a single beam of light passing through a sample 失效
    血液检漏仪比较通过样品的单光束的高吸收带和低吸收带的强度

    公开(公告)号:US4017190A

    公开(公告)日:1977-04-12

    申请号:US597243

    申请日:1975-07-18

    Inventor: Halbert Fischel

    CPC classification number: G01N21/314 G01N21/85 A61M1/1692

    Abstract: A system for detecting small amounts of hemoglobin in a solution detects the ratio between the light transmissivities at separated wavelengths of a sample solution, one of which wavelengths is in a range at which hemoglobin is highly light absorptive. Through the use of the ratios of the signals, a reading of high sensitivity and linearity is provided in the presence of substantial contamination and turbidity in the sample or the system.

    Abstract translation: 用于检测溶液中少量血红蛋白的系统检测样品溶液分离的波长处的透光率之间的比率,其中波长在血红蛋白高度吸收的范围内。 通过使用信号的比例,在样品或系统中存在显着的污染和浊度的情况下提供高灵敏度和线性的读数。

    Hemodialysis system
    20.
    发明授权
    Hemodialysis system 失效
    血液透析系统

    公开(公告)号:US4366051A

    公开(公告)日:1982-12-28

    申请号:US743222

    申请日:1976-11-19

    Inventor: Halbert Fischel

    CPC classification number: A61M1/16 A61M1/1686

    Abstract: A compact self-sterilizable proportioning hemodialysis system alternatively usable with either a coil type or parallel flow artificial dialyzer without material alteration comprises a hydraulic driven dialysate proportioning pump in a positive pressure flow path to provide dialysate in a controlled concentration to a dialysate receiving canister. A coil-type dialyzer within the canister receives dialysate in a recirculating flow from a circulation pump. A venturi in the recirculating flow path provides a negative pressure to pull dialysate through a suction loop, which may alternatively include a parallel flow dialyzer. A conductivity cell, temperature monitor and blood leak detector sample and monitor dialysate from the canister, and to control the dialysate and indicate fault conditions. The system may alternatively function as a recirculating plate-type dialyzer having high dialysis efficiency. In this mode a vortex degasifier recirculating loop and an air separator in the suction loop eliminate entrained gases. Parts of the system may be sterilized by internal means, because the system defines a closed path when certain connections are made. An upright resistive heating steam generator delivers sterilizing steam throughout the liquid flow path which terminates in a pressure relief valve. This increases the steam temperature above the atmospheric water vaporization temperature and maintains the steam at a uniform temperature-pressure equilibrium throughout the flow path. The system requires no central dialysate mixing, yet closely controls the concentration of dialysate utilized.

    Abstract translation: 可替代地使用线圈型或平行流式人造透析器的紧凑型自消毒配比血液透析系统,其不进行材料改变,包括在正压流动路径中的液压驱动透析液配比泵,以将受控浓度的透析液提供给透析液接收罐。 罐内的线圈式透析器在循环泵的循环流中接收透析液。 再循环流路中的文丘里管提供负压以通过吸入回路吸引透析液,该吸入回路可以替代地包括平行流式透析器。 电导池,温度监测器和血液泄漏检测器对来自罐的透析液进行采样和监测,并控制透析液并指示故障状况。 该系统可以替代地用作具有高透析效率的循环板式透析器。 在这种模式下,吸入回路中的涡流脱气器循环回路和空气分离器可以消除夹带的气体。 系统的部件可以通过内部手段消毒,因为系统在确定某些连接时确定了一个闭合的路径。 直立的电阻加热蒸汽发生器在整个液体流动通道中提供消毒蒸汽,其终止于泄压阀。 这将蒸汽温度提高到高于大气水汽化温度,并将蒸汽保持在整个流动路径上均匀的温度 - 压力平衡。 该系统不需要中枢透析液混合,而是密切控制所用透析液的浓度。

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