摘要:
A 1,4-substituted cyclic amine derivative represented by the following formula or a pharmacologically acceptable salt thereof: wherein A, B, C, D, T, Y, and Z each represent a methine or a nitrogen linkage; R1, R2, R3, R4, and R5 each represent a substituent; n represents 0 or an integer of 1 to 3; m represents 0 or an integer of 1 to 6; and p represents an integer of 1 to 3. The compounds have serotonin antagonism. They are therefore clinically useful as medicaments, in particular, for treating, ameliorating, and preventing spastic paralysis. They are also useful as central muscle relaxants for ameliorating myotonia.
摘要:
A method of fabricating a thin-film transistor including forming a polycrystalline semiconductor thin film on a substrate by irradiating with a laser beam an amorphous semiconductor thin film formed on the substrate. Heat treating the polycrystalline semiconductor thin film while the substrate is held by a substrate holder provided in a container containing hydrogen, and processing, prior to or after the heat treating, the polycrystalline semiconductor thin film into a specified configuration.
摘要:
A plant information management system comprising: a seed identification information input device; an individual plant identification information retrieval device; an individual plant identification information input device; a new seed identification information retrieval device; a storage location information retrieval device; a project database management device; a seed database management device; a project database memory device; and a seed database memory device.
摘要:
A CCD color image sensor which prevents unnecessary charge from overflowing in a photoelectric conversion element. An image input apparatus having the CCD color image sensor comprises transferring unit which transfers effective charge accumulated in the photoelectric conversion element provided for each of the colors (R, G and B), extracted as an output signal, to a shift register by opening a shift gate; and discarding unit which discards unnecessary charge accumulated in the photoelectric conversion element by opening the shift gate at different timing from one color to another immediately before the photoelectric conversion element starts accumulating effective charge again. The discarding unit discards unnecessary charge immediately before effective charge accumulates, and discards unnecessary charge by opening the shift gate before unnecessary charge overflows in the photoelectric conversion element.
摘要:
An image reading device has a light source and an image sensor configured to transfer an electric charge accumulated on an opto-electric conversion element to a shift register through a shift gate. A reading controller configured to control image reading inserts a dummy interval into a shift period for which the electric charge is transferred from the opto-electric conversion element so as to shift timing to start sensor reading on every line and to arrange peak positions of noise included in a read image differ from one another on every line.
摘要:
The present invention provides a compound represented by the following formula (I); [wherein T represents a single bond, a C1-C4 alkylene group which may have a substituent and the like; (I-1) formula (I-1) represents a single bond or a double bond; A represents a single bond, a bivalent 5- to 14-membered heterocyclic group which may have a substituent and the like; Y represents a single bond and the like; Z represents a methylene group and the like; ring G represents a phenylene group and the like which may condense with a 5- to 6-membered ring and may have a heteroatom; Ra and Rb are the same as or different from each other and represent a hydrogen atom and the like; W represents a single bond and the like; R′ represents 1 to 4 independent hydrogen atoms and the like; and R″ represents 1 to 4 independent hydrogen atoms and the like] or a salt thereof, or a hydrate thereof.
摘要:
The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a pharmaceutical: wherein R1 and R2 are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5- to 7-membered non-aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like; R3 represents a hydrogen atom or the like; and R6 represents a hydrogen atom or the like. This compound has a superior strength of binding to a 5-HT1A receptor and an antagonism to the receptor, and is useful as an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage.
摘要翻译:本发明涉及由下式表示的化合物,其药理学上可接受的盐或其作为药物的用途:其中R 1和R 2是相邻的取代基 并且与它们各自连接的两个碳原子一起形成5-至7-元非芳族碳环基等,其可以被1至4个选自以下的取代基取代:(1)氧代 基团,(2)羟基等; R 3表示氢原子等; R 6表示氢原子等。 该化合物与5-HT 1A受体的结合强度优异,对受体具有拮抗作用,可用作治疗或预防下尿路症状的药剂,特别是有关尿液储存的症状。
摘要:
There are reduced degradation of the performance of a transistor element, variations in the quality thereof, and the like resulting from the surface roughness of a polycrystalline silicon thin film formed by laser annealing, particularly from the presence of portions in which tramp materials are segregated produced in the rough portions. For this purpose, (1) The projections at the surface portion of the polycrystalline silicon thin film and the portions in which the tramp materials are segregated after laser annealing are chemically, mechanically graded. (2) Likewise, a heat treatment is performed to grow a crystal and planarize the rough portions, while removing the tramp materials in the surface.
摘要:
An electrical equipment module is mounted in, for example, an electrically-powered seat unit for a vehicle. Multiple wire groups (52-56) comprised of wire harnesses or flat cables are led out of a module body (51) of the electrical equipment module (50) from different sides of the module body, thus reducing the outside diameter and thickness of each wire group so that the module body is thin and suited to be mounted in narrow layout space under a seat. By mounting, to the module body, a connector for connecting a printed circuit board (51m) in the module body to an external power supply or an external sensor and by making complicated wiring between the connector and the printed circuit board (51m) in advance in the module body, an assembling (wiring) work at the time of manufacturing the electrical equipment module is simplified.
摘要:
The cyclic amide derivative is defined by the formula (I) or a salt thereof: R1-(CH2)n-Z in which R1 is a group derived from a cyclic amide compound, substituted or unsubstituted, n is zero or an integer of 1 to 10 and Z is ##STR1## R2 being an aryl, a substituted aryl, a cycloalkyl or a heterocyclic group, m being an integer of 1 to 6, R3 being hydrogen or a lower alkyl, R4 being an aryl or a substituted aryl, a cycloalkyl or a heterocyclic group, p being an integer of 1 to 6, provided that the cyclic amide compound is quinazoline-on or quinazoline-dion, R2 and R4 are neither aryl nor substituted aryl. The cyclic amide compound is pharmacologically effective to prevent and treat diseases due to insufficiency of the central choline functions.