公开(公告)号：US4892972A

公开(公告)日：1990-01-09

申请号：US344657

申请日：1989-04-27

申请人： Hobe Schroeder ,  David E. James

发明人： Hobe Schroeder ,  David E. James

IPC分类号： C07C51/487

CPC分类号： C07C51/487

摘要： Aqueous solutions of crude terephthalic acid are purified by hydrogenation in the presence of plural noble metal catalysts in separate layers. Initially, the solution to be purified is passed through a layer of ruthenium-on-carbon catalyst, rhodium-on-carbon catalyst, or platinum-on-carbon catalyst, and thereafter through a layer of palladium-on-carbon catalyst. Optionally, the purified aqueous terephthalic acid solution can be treated further to decrease the 4-carboxybenzaldehyde content thereof by passing it through a layer of rhodium-on-carbon catalyst downstream from the palladium-on-carbon catalyst layer.

摘要翻译： 在多层贵金属催化剂存在下，通过氢化纯化粗对苯二甲酸的水溶液。 最初，待纯化的溶液通过一层碳酸钌催化剂，铑 - 碳催化剂或铂 - 碳催化剂，然后通过一层钯 - 碳催化剂。 任选地，可以进一步处理纯化的对苯二甲酸水溶液，以使其通过使其通过碳 - 钯催化剂层下游的铑 - 碳催化剂层来降低其4-羧基苯甲醛含量。

公开(公告)号：US4822527A

公开(公告)日：1989-04-18

申请号：US134839

申请日：1987-12-14

申请人： David E. James ,  Neal R. Nowicki

发明人： David E. James ,  Neal R. Nowicki

IPC分类号： C07C50/18 ,  C07C45/00

CPC分类号： C07C50/18 ,  Y02P20/584

摘要： A process is disclosed for producing cyclized aromatic compounds by the liquid-phase air oxidation of 2-methyl-substituted biphenyls and diphenylmethanes in an acetic acid medium in the presence of a cobalt-manganese-bromine catalyst or a zirconium-cobalt-manganese-bromine catalyst wherein the mole ratio of cobalt-to-manganese is about 1.0:0.1 to about 1.0:10.0 and the ratio of zirconium-to-cobalt is about 0.005:1.0 to about 0.20:1.0, and mole ratio of bromine to total metals of said cobalt-manganese-bromine catalyst or zirconium-cobalt-manganese-bromine catalyst is from about 0.2:1.0 to about 20.0:1.0, which process comprises conducting the reaction in a batch process at a temperature of from 75.degree. C. to about 250.degree. C. at a pressure of from 1 to 100 atmospheres, or continuously in two stages comprising a first-stage reaction at a temperature of about 75.degree. C. to about 200.degree. C. and a second-stage reaction at a temperature of about 150.degree. C. to about 250.degree. C. and recycling the cobalt-manganese catalyst or the zircnium-cobalt-manganese catalyst by oxalate precipitation of the catalyst at temperatures of about 110.degree. C. to about 200.degree. C. prior to the separation of mother liquor and using about 0.25 to about 2.5 moles of oxalic acid per mole of cobalt and manganese or mole of zirconium-cobalt-manganese and continuously recycling the recovered catalyst metals to the oxidation stages. The products of this novel process, anthraquinones and fluorenones, are useful for the manufacture of dyestuffs and pharmaceuticals.

摘要翻译： 公开了在钴锰溴催化剂或锆 - 钴 - 锰 - 溴存在下，通过在乙酸介质中通过2-甲基取代的联苯和二苯基甲烷的液相空气氧化来生产环化芳族化合物的方法 催化剂，其中钴与锰的摩尔比为约1.0:0.1至约1.0:10.0，锆与钴的摩尔比为约0.005:1.0至约0.20:1.0，溴与总金属的摩尔比为 所述钴 - 锰 - 溴催化剂或锆 - 钴 - 锰 - 溴催化剂的量为约0.2:1.0至约20.0:1.0，该方法包括在75℃至约250℃的间歇过程中进行反应 在1〜100个大气压的压力下，或者在约75℃至约200℃的温度下包括第一阶段反应的两个阶段的连续两个阶段，以及在约 150℃至约250℃并回收 钴锰催化剂或锆 - 钴 - 锰催化剂，在母液分离之前，在约110℃至约200℃的温度下草酸盐沉淀催化剂，并使用约0.25至约2.5摩尔的草酸 每摩尔钴和锰或摩尔的锆 - 钴 - 锰，并将回收的催化剂金属连续循环到氧化阶段。 该新方法的产物，蒽醌和芴酮可用于制造染料和药物。

公开(公告)号：US20170060113A1

公开(公告)日：2017-03-02

申请号：US14833498

申请日：2015-08-24

申请人： Robert A. Kaucic ,  David E. James ,  Herman Lucas Norbert Wiegman ,  Hullas Sehgal

发明人： Robert A. Kaucic ,  David E. James ,  Herman Lucas Norbert Wiegman ,  Hullas Sehgal

IPC分类号： G05B19/042

CPC分类号： G05B19/042 ,  G05B13/041 ,  G05B2219/2639 ,  H02J3/32 ,  Y02B70/3241 ,  Y04S20/227

摘要： Systems and methods of controlling a dispatch operation of an energy storage system are provided. In particular, a degradation value of a present dispatch state of an energy storage system can be determined. The present dispatch state can specify one or more energy storage units presently coupled to the system. The degradation value can be determined based at least in part on one or more operating parameters, such as temperature, open circuit voltage, charge or discharge current, and/or contactor life. The degradation value can then be compared against one or more degradation values associated with one or more candidate dispatch states. A dispatch state can then be selected based on the comparison. One or more energy storage units can be selectively coupled to the energy storage system based at least in part on the selected dispatch state.

摘要翻译： 提供了控制能量存储系统的调度操作的系统和方法。 特别地，可以确定能量存储系统的当前调度状态的劣化值。 目前的调度状态可以指定目前耦合到系统的一个或多个能量存储单元。 至少部分地可以基于一个或多个操作参数（诸如温度，开路电压，充电或放电电流）和/或接触器寿命来确定劣化值。 然后可以将劣化值与与一个或多个候选分派状态相关联的一个或多个退化值进行比较。 然后可以基于比较来选择调度状态。 至少部分地基于所选择的调度状态，一个或多个能量存储单元可以选择性地耦合到能量存储系统。

公开(公告)号：US20110152208A1

公开(公告)日：2011-06-23

申请号：US12865843

申请日：2009-01-14

申请人： Yang Ye ,  David E. James ,  Minjia Tan ,  Gregory J. Cooney ,  Changqiang Ke ,  Edward W. Kraegen ,  Tong Chen ,  Jiming Ye ,  Xiqiang Li

发明人： Yang Ye ,  David E. James ,  Minjia Tan ,  Gregory J. Cooney ,  Changqiang Ke ,  Edward W. Kraegen ,  Tong Chen ,  Jiming Ye ,  Xiqiang Li

IPC分类号： A61K31/7032 ,  C07J9/00 ,  C07H15/00 ,  A61K31/575 ,  A61P3/04 ,  A61P3/10

CPC分类号： A61K31/575 ,  A61K31/704

摘要： The present invention disclosed a medical use of cucurbitane triterpenoids represented by the following formula and isolated from Momordica charantia L. of Cucurbitaceae family in the preparation of medications for prevention and treatment of diabetes and obesity. The above cucurbitane triterpenoids may be acted as a glucose uptake stimulator, an agonist for the translocation of glucose transporter 4(GLUT4) to the cell membrane, and an activator of adenosine monophosphate-activated protein kinase (AMPK). They may have potential for the prevention and treatment of diabetes and obesity.

摘要翻译： 本发明公开了葫芦科三萜类化合物的医学用途，其由葫芦科科的苦瓜属分离，用于制备预防和治疗糖尿病和肥胖症的药物。 上述葫芦巴三萜类化合物可以作为葡萄糖吸收刺激剂，用于将葡萄糖转运蛋白4（GLUT4）转运至细胞膜的激动剂和腺苷一磷酸酯活化蛋白激酶（AMPK）的激活剂。 他们可能有预防和治疗糖尿病和肥胖的潜力。

公开(公告)号：US20100113494A1

公开(公告)日：2010-05-06

申请号：US12443401

申请日：2007-09-30

申请人： Lihong Hu ,  Jia Li ,  Jingya Li ,  Hankun Zhang ,  Zhe Cheng ,  Jiming Ye ,  David E. James ,  Edward W. Kraegen

发明人： Lihong Hu ,  Jia Li ,  Jingya Li ,  Hankun Zhang ,  Zhe Cheng ,  Jiming Ye ,  David E. James ,  Edward W. Kraegen

IPC分类号： A61K31/4375

CPC分类号： C07D455/03

摘要： The present invention provides 13,13a-dihydroberberine derivatives or their physiologically acceptable salts represented by the following formula, pharmaceutical compositions comprising the same, and uses thereof. The 13,13a-dihydroberberine derivatives have an activity of promoting glucose absorption in muscle cells, and the whole animal tests show that the present compounds have effects on improving glucose-tolerance and insulin-resistance, facilitating weight loss, relieving fatty liver and the like. Thus, the present compounds can be used in treating diabetes mellitus, adiposity, fatty liver and complications thereof induced by insulin resistance.

摘要翻译： 本发明提供由下式表示的13,13a-二氢小檗碱衍生物或其生理学上可接受的盐，其包含其的药物组合物及其用途。 13,13a-二氢小檗碱衍生物具有促进肌肉细胞中葡萄糖吸收的活性，整个动物实验表明，本发明化合物具有改善葡萄糖耐量和胰岛素抵抗，促进体重减轻，减轻脂肪肝等作用 。 因此，本发明化合物可用于治疗由胰岛素抵抗引起的糖尿病，肥胖，脂肪肝及其并发症。

公开(公告)号：US06528192B2

公开(公告)日：2003-03-04

申请号：US09726798

申请日：2000-11-30

申请人： Robert A. Lacy ,  David E. James

发明人： Robert A. Lacy ,  David E. James

IPC分类号： H01M800

CPC分类号： H01M8/04955 ,  H01M8/0258 ,  H01M8/04223 ,  H01M8/043 ,  H01M8/04552 ,  H01M8/04559 ,  H01M8/04589 ,  H01M8/04753 ,  Y10S429/90

摘要： An apparatus includes a fuel cell subsystem, a first circuit and a second circuit. The fuel cell subsystem produces power for a load in response to receiving a flow of a reactant, and the first circuit is coupled to the fuel cell subsystem to halt the flow to the fuel cell stack and isolate the fuel cell stack from the load after the flow is halted. The second circuit monitors a characteristic of the fuel cell subsystem and receives power from the stack to dissipate a portion of the reactant that remains in the stack while the flow is halted.

公开(公告)号：US06312482B1

公开(公告)日：2001-11-06

申请号：US09114743

申请日：1998-07-13

申请人： David E. James ,  Paul S. Larsen ,  Mark C. Godden ,  Ted V. Mull, Jr. ,  Paul S. Weitzel

发明人： David E. James ,  Paul S. Larsen ,  Mark C. Godden ,  Ted V. Mull, Jr. ,  Paul S. Weitzel

IPC分类号： C10J320

CPC分类号： C10J3/506 ,  C10J3/485 ,  C10J3/526 ,  C10J3/84 ,  C10J2300/093 ,  C10J2300/0956 ,  C10J2300/0959 ,  C10J2300/1223 ,  C10J2300/1687 ,  C10K1/026

摘要： A combined, integral steam generator coal gasifier includes a vertically elongated, all welded, gas tight enclosure with a burner zone having a double pitch sloping furnace floor and a slag tap extending therethrough. Successive zones located above the burner zone are provided with appropriate tube materials for conveying synthesis gas produced by the coal gasification process. A multi-pass convection pass zone having upflow and downflow passes is located at an upper portion of the enclosure and contains a plurality of superheater (primary and secondary) as well as economizer heating surfaces which extract heat from the synthesis gas to produce steam. An ash remover is connected to the outlet of the convection pass zone to remove ash from the synthesis gas exiting from the convection pass zone. The slag tap located at the bottom of the burner zone communicates with a slag tank or a drag chain deasher for receiving and removing slag from the burner zone.

摘要翻译： 一个组合的整体式蒸汽发生器煤气化器包括一个垂直伸长的，全焊接的，气密的外壳，其燃烧器区域具有双倾斜倾斜的炉底和从其延伸穿过的炉渣。 位于燃烧器区域上方的连续区域设置有用于输送由煤气化过程产生的合成气的合适的管材料。 具有上流和下流通过的多通对流通道位于外壳的上部并且包含多个过热器（初级和次级）以及从合成气提取热量以产生蒸汽的节能器加热表面。 灰尘去除器连接到对流通过区的出口，以从从对流通过区域排出的合成气中除去灰分。 位于燃烧器区域底部的炉渣与渣槽或拖链脱渣器连通，用于从燃烧器区域接收和除去炉渣。

公开(公告)号：US6058858A

公开(公告)日：2000-05-09

申请号：US77483

申请日：1998-05-29

申请人： Felix Belin ,  David E. James ,  David J. Walker ,  Kiplin C. Alexander

发明人： Felix Belin ,  David E. James ,  David J. Walker ,  Kiplin C. Alexander

IPC分类号： F22B31/00 ,  F23C10/02 ,  F23C10/08 ,  F23G5/00 ,  F23G7/00 ,  F23J3/00

CPC分类号： F23C10/02 ,  F22B31/0084 ,  F23C10/08

摘要： A circulating fluidized bed (CFB) reactor or combustor having an internal impact type primary particle separator which provides for internal return of all primary collected solids to a bottom portion of the reactor or combustor for subsequent recirculation without external and internal recycle conduits. The CFB reactor enclosure or furnace is provided with plural furnace outlets. This construction permits increased furnace depths and reduced furnace widths, resulting in a compact design.

摘要翻译： PCT No.PCT / US96 / 19039 Sec。 371日期1998年6月29日第 102（e）1998年6月29日PCT PCT 1996年11月29日PCT公布。 公开号WO97 / 20172 日期1997年6月5日具有内部冲击型一次粒子分离器的循环流化床（CFB）反应器或燃烧器，其提供所有初级收集的固体内部返回到反应器或燃烧器的底部，用于随后的再循环，而不需要外部和内部循环 导管。 CFB反应器外壳或炉具有多个炉出口。 这种结构允许增加炉深度和减小炉宽，从而实现紧凑的设计。

公开(公告)号：US5080798A

公开(公告)日：1992-01-14

申请号：US555766

申请日：1990-06-25

申请人： David E. James

发明人： David E. James

IPC分类号： G01N30/02 ,  G01N30/62 ,  G01N30/74 ,  G01N33/44

CPC分类号： G01N33/442 ,  G01N2030/027 ,  G01N2030/625 ,  G01N30/74

摘要： There are provided methods for monitoring the oligomeric content of prepolymers and polymers, which methods employ high-performance liquid chromatographic techniques. Typically, the methods of the present invention may be used to determine the oligomeric content of polyethylene terephthalate polymers and prepolymers.

摘要翻译： 提供了监测预聚物和聚合物的低聚物含量的方法，该方法采用高效液相色谱技术。 通常，本发明的方法可用于测定聚对苯二甲酸乙二醇酯聚合物和预聚物的低聚物含量。

公开(公告)号：US4804501A

公开(公告)日：1989-02-14

申请号：US185432

申请日：1988-04-25

申请人： David E. James ,  Neal R. Nowicki

发明人： David E. James ,  Neal R. Nowicki

IPC分类号： C07C50/18 ,  C07B33/00 ,  C07C45/00

CPC分类号： C07C50/18 ,  Y02P20/584

摘要： A process is disclosed for producing cyclized aromatic compounds by the liquid-phase air oxidation of 2-methyl-substituted biphenyls and diphenylmethanes in an acetic acid medium in the presence of a cobalt-manganese-bromine catalyst or a zirconium-cobalt-manganese-bromine catalyst wherein the mole ratio of cobalt-to-manganese is about 1.0:0.1 to about 1.0:10.0 and the ratio of zirconium-to-cobalt is about 0.005:1.0 to about 0.20:1.0, and mole ratio of bromine to total metals of said cobalt-manganese-bromine catalyst or zirconium-cobalt-manganese-bromine catalyst is from about 0.2:1.0 to about 20.0:1.0, which process comprises conducting the reaction in a batch process at a temperature of from 75.degree. C. to about 250.degree. C. at a pressure of from 1 to 100 atmospheres, or continuously in two stages comprising a first-stage reaction at a temperature of about 75.degree. C. to about 200.degree. C. and a second-stage reaction at a temperature of about 150.degree. C. to about 250.degree. C. and recycling the cobalt-manganese catalyst or the zirconium-cobalt-manganese catalyst by oxalate precipitation of the catalyst at temperatures of about 110.degree. C. to about 200.degree. C. prior to the separation of mother liquor and using about 0.25 to about 2.5 moles of oxalic acid per mole of cobalt and manganese or mole of zirconium-cobalt-manganese and continuously recycling the recovered catalyst metals to the oxidation stages. The products of this novel process, anthraquinones and fluorenones, are useful for the manufacture of dyestuffs and pharmaceuticals.

摘要翻译： 公开了在钴锰溴催化剂或锆 - 钴 - 锰 - 溴存在下，通过在乙酸介质中通过2-甲基取代的联苯和二苯基甲烷的液相空气氧化来生产环化芳族化合物的方法 催化剂，其中钴与锰的摩尔比为约1.0:0.1至约1.0:10.0，锆与钴的摩尔比为约0.005:1.0至约0.20:1.0，溴与总金属的摩尔比为 所述钴 - 锰 - 溴催化剂或锆 - 钴 - 锰 - 溴催化剂的量为约0.2:1.0至约20.0:1.0，该方法包括在75℃至约250℃的间歇过程中进行反应 在1〜100个大气压的压力下，或者在约75℃至约200℃的温度下包括第一阶段反应的两个阶段的连续两个阶段，以及在约 150℃至约250℃并回收 钴 - 锰催化剂或锆 - 钴 - 锰催化剂，在母液分离之前，在约110℃至约200℃的温度下草酸盐沉淀催化剂，并使用约0.25至约2.5摩尔的草酸 每摩尔钴和锰或摩尔的锆 - 钴 - 锰，并将回收的催化剂金属连续循环到氧化阶段。 该新方法的产物，蒽醌和芴酮可用于制造染料和药物。