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公开(公告)号：US20090012129A1
公开(公告)日：2009-01-08
申请号：US12110815
申请日：2008-04-28
IPC分类号： A61K31/195 , C07C229/00 , A61K31/44 , A61P17/00 , A61P35/00 , C07D213/72
CPC分类号： C07D213/30 , A61K8/42 , A61K8/442 , A61K8/4926 , A61K2800/92 , A61Q7/00 , A61Q19/00 , A61Q19/08 , C07C233/47 , C07C233/87 , C07C235/52 , C07C275/28 , C07C275/42 , C07D213/54 , C07D213/75
摘要： Novel biaromatic compounds that modulate peroxisome proliferator-activator receptors, known as PPAR, having the formula (I): are formulated into pharmaceutical compositions useful in human or veterinary medicine, or alternatively, in cosmetic compositions.
摘要翻译： 调节具有式（I）的过氧化物酶体增殖物激活剂受体（称为PPAR）的新型双芳族化合物被配制成可用于人类或兽医学或可替代地在化妆品组合物中的药物组合物。
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公开(公告)号：US08383652B2
公开(公告)日：2013-02-26
申请号：US12110815
申请日：2008-04-28
IPC分类号： A01N43/40 , A01N47/28 , A61K31/44 , A61K31/17 , C07D213/22 , C07C335/00
CPC分类号： C07D213/30 , A61K8/42 , A61K8/442 , A61K8/4926 , A61K2800/92 , A61Q7/00 , A61Q19/00 , A61Q19/08 , C07C233/47 , C07C233/87 , C07C235/52 , C07C275/28 , C07C275/42 , C07D213/54 , C07D213/75
摘要： Novel biaromatic compounds that modulate peroxisome proliferator-activator receptors, known as PPAR, having the formula (I): are formulated into pharmaceutical compositions useful in human or veterinary medicine, or alternatively, in cosmetic compositions.
摘要翻译： 调节具有式（I）的过氧化物酶体增殖物激活剂受体（称为PPAR）的新型双芳族化合物被配制成可用于人类或兽医学或可替代地在化妆品组合物中的药物组合物。
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13.发明申请Novel polycyclic compounds which modulate PPARgamma type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效调节PPARγ型受体的新型多环化合物及其组合的美容/药物组合物公开(公告)号：US20060009484A1
公开(公告)日：2006-01-12
申请号：US11149551
申请日：2005-06-10
申请人： Laurence Clary , Pascal Collette , Michel Rivier , Andre Jomard
发明人： Laurence Clary , Pascal Collette , Michel Rivier , Andre Jomard
IPC分类号： A61K31/4745 , A61K31/44 , A61K31/47
CPC分类号： C07D257/04 , C07C233/17 , C07C233/36 , C07C235/66 , C07C237/22 , C07C237/30 , C07C271/20 , C07C275/40 , C07C323/62 , C07C335/12 , C07C335/20 , C07C2603/18 , C07D211/16 , C07D271/10 , C07D295/185 , C07D295/192
摘要： Novel polycyclic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有以下结构式（I）的新型多环化合物被配制成适用于人或兽医学（在皮肤病学以及心血管疾病，免疫疾病和/或与脂质代谢相关的疾病领域）中施用的药物组合物， 或替代地，进入化妆品组合物。
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14.发明授权Biaromatic compounds which activate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效激活PPARγ型受体的双芳族化合物和包含它们的化妆品/药物组合物公开(公告)号：US07452878B2
公开(公告)日：2008-11-18
申请号：US11131302
申请日：2005-05-18
IPC分类号： A61K31/535 , A61K31/425 , C07D265/28 , C07D401/00 , C07D261/02
CPC分类号： C07D207/27 , A61K8/44 , A61K8/49 , A61Q5/00 , A61Q19/00 , A61Q19/08 , C07C229/36 , C07C233/47 , C07C233/54 , C07C233/55 , C07C233/65 , C07C233/81 , C07C233/87 , C07C235/52 , C07C235/60 , C07C235/74 , C07C235/84 , C07C237/20 , C07C237/40 , C07C243/28 , C07C271/22 , C07C275/42 , C07C323/60 , C07C335/22 , C07C2601/02 , C07C2601/14 , C07D207/335 , C07D211/16 , C07D211/34 , C07D211/62 , C07D213/38 , C07D213/40 , C07D263/32 , C07D265/30 , C07D271/06 , C07D271/10 , C07D295/088 , C07D295/185 , C07D295/205 , C07D307/81 , C07D333/20
摘要： Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有下述结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物（皮肤病学以及与心血管疾病，免疫疾病和/或脂质代谢相关的疾病领域）的药物组合物， 或替代地，进入化妆品组合物。
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15.发明申请Novel biaromatic compounds which activate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效活化PPARγ型受体的新型双芳族化合物和包含它们的化妆品/药物组合物公开(公告)号：US20080070957A1
公开(公告)日：2008-03-20
申请号：US11898910
申请日：2007-09-17
IPC分类号： A61K31/4245 , A61P17/00 , A61P3/00 , A61P35/00 , A61P37/00 , A61P9/00 , A61Q5/00 , C07D271/10 , C12N5/06
CPC分类号： C07D285/14 , A61K31/4245 , C07C229/34 , C07C237/22 , C07C271/18 , C07C271/22 , C07C275/42 , C07C2601/14 , C07D211/16 , C07D241/44 , C07D271/10 , C07D295/13 , C07D295/185 , C07D401/12 , C07D409/12 , C07D413/12 , C07D417/14
摘要： Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有下述结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物（皮肤病学以及与心血管疾病，免疫疾病和/或脂质代谢相关的疾病领域）的药物组合物， 或替代地，进入化妆品组合物。
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16.发明申请Novel polycyclic compounds which modulate PPARgamma type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效调节PPARγ型受体的新型多环化合物及其组合的美容/药物组合物公开(公告)号：US20070093487A1
公开(公告)日：2007-04-26
申请号：US11523701
申请日：2006-09-20
申请人： Laurence Clary , Pascal Collette , Michel Rivier , Andre Jomard
发明人： Laurence Clary , Pascal Collette , Michel Rivier , Andre Jomard
IPC分类号： A61K31/5375 , A61K31/445 , A61K31/4245 , A61K31/41 , A61K31/22 , A61K31/198 , A61K31/165
CPC分类号： C07D257/04 , C07C233/17 , C07C233/36 , C07C235/66 , C07C237/22 , C07C237/30 , C07C271/20 , C07C275/40 , C07C323/62 , C07C335/12 , C07C335/20 , C07C2603/18 , C07D211/16 , C07D271/10 , C07D295/185 , C07D295/192
摘要： Novel polycyclic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有以下结构式（I）的新型多环化合物被配制成适用于人或兽医学（在皮肤病学以及心血管疾病，免疫疾病和/或与脂质代谢相关的疾病领域）中施用的药物组合物， 或替代地，进入化妆品组合物。
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17.发明授权Biaromatic compounds which activate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效活化PPARγ型受体的双芳族化合物和由其构成的美容/药物组合物公开(公告)号：US07807669B2
公开(公告)日：2010-10-05
申请号：US12266096
申请日：2008-11-06
IPC分类号： A61K31/425 , A61K31/535 , C07D261/02 , C07D265/28 , C07D401/00
CPC分类号： C07D207/27 , A61K8/44 , A61K8/49 , A61Q5/00 , A61Q19/00 , A61Q19/08 , C07C229/36 , C07C233/47 , C07C233/54 , C07C233/55 , C07C233/65 , C07C233/81 , C07C233/87 , C07C235/52 , C07C235/60 , C07C235/74 , C07C235/84 , C07C237/20 , C07C237/40 , C07C243/28 , C07C271/22 , C07C275/42 , C07C323/60 , C07C335/22 , C07C2601/02 , C07C2601/14 , C07D207/335 , C07D211/16 , C07D211/34 , C07D211/62 , C07D213/38 , C07D213/40 , C07D263/32 , C07D265/30 , C07D271/06 , C07D271/10 , C07D295/088 , C07D295/185 , C07D295/205 , C07D307/81 , C07D333/20
摘要： Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有下述结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物（皮肤病学以及与心血管疾病，免疫疾病和/或脂质代谢相关的疾病领域）的药物组合物， 或替代地，进入化妆品组合物。
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18.发明授权Biaromatic compounds which activate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效激活PPARγ型受体的双芳族化合物和包含它们的化妆品/药物组合物公开(公告)号：US07582663B2
公开(公告)日：2009-09-01
申请号：US11898910
申请日：2007-09-17
IPC分类号： A61K31/4245 , A61K31/135 , C07C233/64
CPC分类号： C07D285/14 , A61K31/4245 , C07C229/34 , C07C237/22 , C07C271/18 , C07C271/22 , C07C275/42 , C07C2601/14 , C07D211/16 , C07D241/44 , C07D271/10 , C07D295/13 , C07D295/185 , C07D401/12 , C07D409/12 , C07D413/12 , C07D417/14
摘要： Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有下述结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物（皮肤病学以及与心血管疾病，免疫疾病和/或脂质代谢相关的疾病领域）的药物组合物， 或替代地，进入化妆品组合物。
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19.发明授权Polycyclic compounds which modulate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效调节PPARγ型受体的多环化合物和由其组成的化妆品/药物组合物公开(公告)号：US07307078B2
公开(公告)日：2007-12-11
申请号：US11523701
申请日：2006-09-20
申请人： Laurence Clary , Pascal Collette , Michel Rivier , Andre Jomard
发明人： Laurence Clary , Pascal Collette , Michel Rivier , Andre Jomard
IPC分类号： A61K8/02 , A61K31/5375 , A61K31/41 , A61K31/433 , A61K31/4245 , A61K31/085 , A61K47/12
CPC分类号： C07D257/04 , C07C233/17 , C07C233/36 , C07C235/66 , C07C237/22 , C07C237/30 , C07C271/20 , C07C275/40 , C07C323/62 , C07C335/12 , C07C335/20 , C07C2603/18 , C07D211/16 , C07D271/10 , C07D295/185 , C07D295/192
摘要： Novel polycyclic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有以下结构式（I）的新型多环化合物被配制成适用于人或兽医学（在皮肤病学以及心血管疾病，免疫疾病和/或与脂质代谢相关的疾病领域）中施用的药物组合物， 或替代地，进入化妆品组合物。
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20.发明授权Biaromatic compounds which activate PPARgamma type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效激活PPARγ型受体的双芳族化合物和包含它们的化妆品/药物组合物公开(公告)号：US07285568B2
公开(公告)日：2007-10-23
申请号：US11135499
申请日：2005-05-24
IPC分类号： A61K31/42 , A61K31/5377 , C07D261/02 , C07D265/30
CPC分类号： A61K31/4245 , C07C235/66 , C07C271/22 , C07C275/42 , C07D213/40 , C07D213/79 , C07D235/06 , C07D241/44 , C07D263/48 , C07D271/10 , C07D285/14 , C07D295/13 , C07D295/185 , C07D333/36 , C07D417/04 , Y02P20/55
摘要： Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要翻译： 具有下述结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物（皮肤病学以及与心血管疾病，免疫疾病和/或脂质代谢相关的疾病领域）的药物组合物， 或替代地，进入化妆品组合物。
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