公开(公告)号：US09168047B2

公开(公告)日：2015-10-27

申请号：US12753788

申请日：2010-04-02

Applicant: John T. To ,  Dan Zaretzka ,  Myra I. L. Fabro ,  Stewart M. Kume

Inventor： John T. To ,  Dan Zaretzka ,  Myra I. L. Fabro ,  Stewart M. Kume

IPC: A61B17/32 ,  A61B17/16 ,  A61B17/3207 ,  A61B17/88 ,  A61B17/00 ,  A61B19/00

CPC classification number: A61B17/1617 ,  A61B17/1671 ,  A61B17/32002 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/8811 ,  A61B2017/00261 ,  A61B2017/003 ,  A61B2017/00331 ,  A61B2017/00398 ,  A61B2017/00685 ,  A61B2017/00734 ,  A61B2017/00867 ,  A61B2017/320064 ,  A61B2017/320733 ,  A61B2017/320775 ,  A61B2090/064

Abstract: Systems and methods for minimally invasive discectomy procedures are described herein. The systems include a bendable flexible cannula may have a straight configuration suitable for insertion and withdrawal into spinal tissue, and a curved configuration suitable for accessing certain areas of a vertebral disc that may be difficult to reach in the straight configuration. A cannula is straightened by inserting a straight stylet therethrough. The straight stylet may have a deflectable region that facilitates its insertion into the cannula. Removal of a straight stylet from a cannula may allow the cannula to assume its curved configuration. The systems may be used with tissue removal devices, and certain variations of tissue removal devices may include a collector for aspiration, as well as a travel limiter to restrict inadvertent motions of the tissue removal devices within a vertebral structure.

Abstract translation: 本文描述了用于微创椎间盘切除术的系统和方法。 该系统包括可弯曲的柔性套管可以具有适于插入和退回到脊髓组织中的直线构型，以及适于进入可能难以以直线构型到达的椎间盘的某些区域的弯曲构造。 通过插入一个直管心针将套管拉直。 直的探针可以具有有助于其插入插管的可偏转区域。 从插管中移除直管心可以允许套管呈现其弯曲构型。 系统可以与组织去除装置一起使用，并且组织去除装置的某些变型可以包括用于抽吸的收集器以及限制在椎骨结构内的组织去除装置的无意的运动的行进限制器。

公开(公告)号：US08177781B2

公开(公告)日：2012-05-15

申请号：US11431213

申请日：2006-05-10

Applicant: Simon W. H. Thomas ,  Peter S. Edelstein ,  John T. To ,  Benjamin T. Nordell ,  Stuart D. Edwards

Inventor： Simon W. H. Thomas ,  Peter S. Edelstein ,  John T. To ,  Benjamin T. Nordell ,  Stuart D. Edwards

IPC: A61B18/18

CPC classification number: A61B18/00 ,  A61B17/0625 ,  A61B18/02 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1485 ,  A61B2017/00805 ,  A61B2017/00867 ,  A61B2018/00029 ,  A61B2018/00035 ,  A61B2018/00178 ,  A61B2018/00285 ,  A61B2018/00523 ,  A61B2018/00553 ,  A61B2018/00559 ,  A61B2018/00916 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2218/007 ,  A61N1/06 ,  A61N7/022 ,  C08L2201/12

Abstract: Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.

Abstract translation: 提供了用于通过向尿道和/或膀胱出口附近的组织施加能量来改变组织依从性而不使尿道和/或膀胱出口腔基本上变窄来治疗女性尿失禁的装置和方法。 该装置包括细长轴，其具有用于治疗尿道组织的装置和可展开装置的可扩展构件。 可膨胀构件被构造成锚固在膀胱出口上，以仅使用触觉反馈来将用于治疗的装置设置在尿道中的期望的治疗部位。 用于治疗的装置可以包括无针RF电极，超声换能器或构造成通过中空针前进的低温探针，每个都被设计为减少或消除与尿失禁相关的症状。

公开(公告)号：US20120083810A1

公开(公告)日：2012-04-05

申请号：US13309986

申请日：2011-12-02

Applicant: PAUL Q. ESCUDERO ,  John T. To ,  Christopher James Danek

Inventor： PAUL Q. ESCUDERO ,  John T. To ,  Christopher James Danek

IPC: A61B17/3207

CPC classification number: A61B17/320783 ,  A61B17/320758 ,  A61B2017/00685 ,  A61B2017/22038 ,  A61B2017/22047 ,  A61B2017/22048 ,  A61B2017/22068 ,  A61B2017/22082 ,  A61B2017/320064 ,  A61M25/09

Abstract: The devices and methods generally relate to treatment of occluded body lumens. In particular, the present devices and method relate to removal of the occluding material from the blood vessels as well as other body lumens.

Abstract translation: 装置和方法通常涉及封闭体腔的治疗。 特别地，本发明的装置和方法涉及从血管以及其它体腔去除闭塞材料。

公开(公告)号：US20120022564A1

公开(公告)日：2012-01-26

申请号：US13245816

申请日：2011-09-26

Applicant: David Batten ,  John T. To ,  Hiep Nguyen

Inventor： David Batten ,  John T. To ,  Hiep Nguyen

IPC: A61B17/32

CPC classification number: A61B17/32002 ,  A61B17/1615 ,  A61B17/1617 ,  A61B17/1671 ,  A61B2017/320064

Abstract: Disclosed herein are tissue-removal devices and methods for treating spinal diseases using such devices. The tissue-removal devices may comprise a cable and/or extendable elements with a retracted and a deployed configuration. The cable and/or extendable elements may be distally supported and restrained by a support element such that the support element may be pushed transversely away when the extendable element is distally extended into its deployed configuration. An annular cutting element may be provided about the distal end of the extendable element or the support element. Various configurations of the extendable and support elements are described herein, as well as methods of using tissue-removal devices with extendable and support elements coupled by an annular cutting element for treating spinal diseases.

Abstract translation: 本文公开了使用这种装置治疗脊柱疾病的组织去除装置和方法。 组织去除装置可以包括具有缩回和展开构造的电缆和/或可延伸元件。 电缆和/或可延伸元件可以由支撑元件远端地支撑和限制，使得当可延伸元件向远侧延伸到其展开构型时，支撑元件可被横向推开。 可以围绕可延伸元件的远端或支撑元件设置环形切割元件。 本文描述了可延伸和支撑元件的各种构造，以及使用具有通过环形切割元件联接以治疗脊柱疾病的可延伸和支撑元件的组织去除装置的方法。

公开(公告)号：US20090062871A1

公开(公告)日：2009-03-05

申请号：US12199701

申请日：2008-08-27

Applicant: Singfatt Chin ,  John T. To ,  Lex P. Jansen ,  Myra I.L. Fabro

Inventor： Singfatt Chin ,  John T. To ,  Lex P. Jansen ,  Myra I.L. Fabro

IPC: A61F5/00 ,  A61B1/00 ,  A61M31/00 ,  A61M29/00

CPC classification number: A61B17/0218 ,  A61B1/00082 ,  A61B1/0051 ,  A61B1/012 ,  A61B1/3135 ,  A61B2017/003 ,  A61B2017/00557 ,  A61B2017/320048 ,  A61B2090/08021 ,  A61B2217/005 ,  A61M25/0054 ,  A61M25/0138 ,  A61M25/10 ,  Y10T29/49826

Abstract: Balloon cannula systems may be used for accessing and visualizing the spine and related methods of treatment, including a forward-looking balloon system for creating a working space and the balloon system having atraumatic dissection capability to allow visualization in spine. The devices and methods described may be used, for example, to perform annulus repair, herniated disc excision, and denervation of neurological tissue; to dispense pharmacological agents and/or cell or tissue therapy agents; to diagnose disc degeneration and bony degeneration, spinal stenosis, and nucleus decompression, and to perform disc augmentation.

Abstract translation: 气球套管系统可用于访问和可视化脊柱和相关治疗方法，包括用于创建工作空间的前瞻性气囊系统和具有无创伤解剖能力以允许在脊柱中可视化的球囊系统。 所描述的装置和方法可以用于例如执行环带修复，突出的椎间盘切除和神经组织的去神经支配; 分配药理学试剂和/或细胞或组织治疗剂; 诊断椎间盘退变和骨变性，脊柱狭窄和细胞核减压，并进行椎间盘增大。

公开(公告)号：US20090018567A1

公开(公告)日：2009-01-15

申请号：US12215855

申请日：2008-06-30

Applicant: Paul Quentin Escudero ,  John T. To ,  Christopher James Danek ,  Uriel Hiram Chee ,  August Christopher Pombo ,  Torrey Smith ,  Brenda Hann

Inventor： Paul Quentin Escudero ,  John T. To ,  Christopher James Danek ,  Uriel Hiram Chee ,  August Christopher Pombo ,  Torrey Smith ,  Brenda Hann

IPC: A61B17/3207

CPC classification number: A61B17/320758 ,  A61B2017/003 ,  A61B2017/00685 ,  A61B2017/22039 ,  A61B2017/22044 ,  A61B2017/22068 ,  A61B2017/22094 ,  A61B2017/2929 ,  A61B2017/320775

Abstract: The devices and methods generally relate to treatment of occluded body lumens. In particular, the present devices and method relate to removal of the occluding material from the blood vessels as well as other body lumens.

公开(公告)号：US09610095B2

公开(公告)日：2017-04-04

申请号：US12582638

申请日：2009-10-20

Applicant: John T. To

Inventor： John T. To

IPC: A61B17/34 ,  A61B10/06 ,  A61B1/313 ,  A61B5/00 ,  A61B8/12 ,  A61B17/02 ,  A61B17/00 ,  A61B17/32 ,  A61B90/00

CPC classification number: A61B17/3417 ,  A61B1/3135 ,  A61B5/0084 ,  A61B8/12 ,  A61B10/06 ,  A61B17/0218 ,  A61B90/361 ,  A61B2017/00261 ,  A61B2017/003 ,  A61B2017/00907 ,  A61B2017/320064 ,  A61B2017/3419

Abstract: Retractor cannula systems may be used for accessing and visualizing the spine and related methods of treatment, including a forward-looking retractor cannula system for creating a working space and the retractor cannula system having atraumatic dissection capability to allow visualization in spine. The devices and methods described may be used, for example, to perform annulus repair, herniated disc excision, and denervation of neurological tissue; to dispense pharmacological agents and/or cell or tissue therapy agents; to diagnose disc degeneration and bony degeneration, spinal stenosis, and nucleus decompression, and to perform disc augmentation.

公开(公告)号：US09049986B2

公开(公告)日：2015-06-09

申请号：US13237866

申请日：2011-09-20

Applicant: Lex P. Jansen ,  John T. To ,  John W. Davis ,  Stewart M. Kume ,  Wendy Twardzik

Inventor： Lex P. Jansen ,  John T. To ,  John W. Davis ,  Stewart M. Kume ,  Wendy Twardzik

IPC: A61B1/00 ,  A61B1/005 ,  A61B1/313 ,  A61B17/16 ,  A61B17/32 ,  A61B17/3205 ,  A61B17/34 ,  A61B1/015 ,  A61B1/018 ,  A61B17/17 ,  A61B17/22 ,  A61B17/00 ,  A61B19/00

CPC classification number: A61B1/00154 ,  A61B1/005 ,  A61B1/015 ,  A61B1/018 ,  A61B1/3135 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/1604 ,  A61B17/1637 ,  A61B17/1644 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/22031 ,  A61B17/320016 ,  A61B17/32053 ,  A61B17/3415 ,  A61B17/3423 ,  A61B2017/00261 ,  A61B2017/00398 ,  A61B2017/0262 ,  A61B2090/3937

Abstract: Systems and methods for treating spinal stenosis include endoscopic access devices and bone removal devices used to perform a foraminotomy or other bone removal procedures. A bone removal device includes a cannulotome with an endoscopic imaging lumen. Optionally, an endoscope retaining device can be used to facilitate advancement of the endoscope through the cannulotome.

Abstract translation: 用于治疗脊柱狭窄的系统和方法包括用于进行椎间孔切开术或其他骨移除手术的内窥镜检查装置和骨移除装置。 骨去除装置包括具有内窥镜成像内腔的插管切除器。 可选地，内窥镜保持装置可以用于促进内窥镜通过管腔切除器的前进。

公开(公告)号：US08808320B2

公开(公告)日：2014-08-19

申请号：US12825251

申请日：2010-06-28

Applicant: David Batten ,  John T. To ,  Hiep Nguyen

Inventor： David Batten ,  John T. To ,  Hiep Nguyen

IPC: A61B17/32

CPC classification number: A61B17/32002 ,  A61B17/1615 ,  A61B17/1617 ,  A61B17/1671 ,  A61B2017/320064

Abstract: Disclosed herein are tissue-removal devices and methods for treating spinal diseases using such devices. The tissue-removal devices may comprise a cable and/or extendable elements with a retracted and a deployed configuration. The cable and/or extendable elements may be distally supported and restrained by a support element such that the support element may be pushed transversely away when the extendable element is distally extended into its deployed configuration. An annular cutting element may be provided about the distal end of the extendable element or the support element. Various configurations of the extendable and support elements are described herein, as well as methods of using tissue-removal devices with extendable and support elements coupled by an annular cutting element for treating spinal diseases.

Abstract translation: 本文公开了使用这种装置治疗脊柱疾病的组织去除装置和方法。 组织去除装置可以包括具有缩回和展开构造的电缆和/或可延伸元件。 电缆和/或可延伸元件可以由支撑元件远端地支撑和限制，使得当可延伸元件向远侧延伸到其展开构型时，支撑元件可被横向推开。 可以围绕可延伸元件的远端或支撑元件设置环形切割元件。 本文描述了可延伸和支撑元件的各种构造，以及使用具有通过环形切割元件联接以治疗脊柱疾病的可延伸和支撑元件的组织去除装置的方法。

公开(公告)号：US20120197247A1

公开(公告)日：2012-08-02

申请号：US13443713

申请日：2012-04-10

Applicant: Simon W. H. Thomas ,  Peter S. Edelstein ,  John T. To ,  Benjamin T. Nordell ,  Stuart D. Edwards

Inventor： Simon W. H. Thomas ,  Peter S. Edelstein ,  John T. To ,  Benjamin T. Nordell ,  Stuart D. Edwards

IPC: A61B18/18

CPC classification number: A61B18/00 ,  A61B17/0625 ,  A61B18/02 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1485 ,  A61B2017/00805 ,  A61B2017/00867 ,  A61B2018/00029 ,  A61B2018/00035 ,  A61B2018/00178 ,  A61B2018/00285 ,  A61B2018/00523 ,  A61B2018/00553 ,  A61B2018/00559 ,  A61B2018/00916 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2218/007 ,  A61N1/06 ,  A61N7/022 ,  C08L2201/12

Abstract: Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.

Abstract translation: 提供了用于通过向尿道和/或膀胱出口附近的组织施加能量来改变组织依从性而不使尿道和/或膀胱出口腔基本上变窄来治疗女性尿失禁的装置和方法。 该装置包括细长轴，其具有用于治疗尿道组织的装置和可展开装置的可扩展构件。 可膨胀构件被构造成锚固在膀胱出口上，以仅使用触觉反馈来将用于治疗的装置设置在尿道中的期望的治疗部位。 用于治疗的装置可以包括无针RF电极，超声换能器或构造成通过中空针前进的低温探针，每个都被设计为减少或消除与尿失禁相关的症状。