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公开(公告)号：US09789057B2
公开(公告)日：2017-10-17
申请号：US13555472
申请日：2012-07-23
IPC分类号： A61K9/00
CPC分类号： A61K9/0036 , A61K9/0034
摘要： A pharmaceutical formulation to treat vaginal conditions in a human patient comprises: at least one active agent; a modified release dosage form which provides extended release of the anti-infective agent upon vaginal administration to the patient; and wherein the formulation, when containing a total dose of the anti-infective agent of about 25 μg to about 500 mg based on the active agent will produce a plasma concentration versus time curve (ng/mL versus hours) having an area under the curve (AUC) of less than about 600 ng/mL·hr.
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公开(公告)号：US06488956B1
公开(公告)日：2002-12-03
申请号：US09448744
申请日：1999-11-24
IPC分类号： A61K4700
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , A61K2300/00 , A23V2250/71 , A23V2250/211 , A23V2250/704 , A23V2250/712 , A23V2250/708 , A23V2250/702 , A23V2250/705 , A23V2250/1578 , A23V2250/1592 , A23V2250/1642 , A23V2250/1608 , A23V2250/1586 , A23V2250/16 , A23V2250/1588 , A23V2250/156 , A23V2250/70
摘要： Multi-vitamin and mineral supplements for administration to non-lactating women, which comprise specific regimens of vitamins and minerals tailored to meet the physiological needs of said women. Methods for optimizing the health of women by providing multi-vitamin and mineral supplements which are specifically tailored to achieve optimal regulation of growth, maintenance and repair of body tissue during specific stages of life with minimal side effects. Methods for formulating a multi-vitamin and mineral supplement that optimize the health of a woman and which comprise identifying life stages which correlate to specific nutritional requirements as a result of varying physiological conditions during a lifetime and selecting specific types and optimal amounts of vitamins and minerals for said life stages.
摘要翻译： 多种维生素和矿物质补充剂用于非哺乳妇女的管理，其中包括针对所述妇女的生理需要量身定制的维生素和矿物质的具体方案。 通过提供多种维生素和矿物质补充剂来优化妇女健康的方法，这些补充剂专门用于在生命的特定阶段实现人体组织的生长，维持和修复的最佳调节，并具有最小的副作用。 制备多种维生素和矿物质补充剂的方法，其优化女性的健康，其包括鉴定生命周期中与不同生理条件相关的特定营养需求的生命阶段，并选择特定类型和最佳量的维生素和矿物质 对于生命阶段
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公开(公告)号：US5869084A
公开(公告)日：1999-02-09
申请号：US474071
申请日：1995-06-07
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , Y10S514/905
摘要： Multi-vitamin and mineral supplements for administration to lactating, non-lactating, and menopausal women, which comprise specific regimens of critical nutritional agents. The supplements are specifically tailored to meet nutritional requirements and maintain a woman's health during each stage of life.
摘要翻译： 用于哺乳期，非哺乳期和绝经期妇女的多种维生素和矿物质补充剂，其包括关键营养剂的特定方案。 补品是专门为满足营养需求量身定制，并在生命的每个阶段保持女性的健康。
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公开(公告)号：US5730997A
公开(公告)日：1998-03-24
申请号：US712436
申请日：1996-09-11
CPC分类号： A61K9/0095 , Y10S514/849 , Y10S514/85 , Y10S514/974
摘要： A substantially tasteless liquid phramaceutical delivery system containing an active material and a high osmolarity aqueous system comprising (i) water; (ii) about 20% to about 45% by weight sugar derivative; (iii) about 10% to about 15% by weight hydrogenated maltose syrup; and (iv) about 0% to about 35% by weight polyhydroxy alcohol.
摘要翻译： 一种基本上无味的液体药物递送系统，其含有活性物质和高摩尔渗透浓度水系统，其包含（i）水; （ii）约20％至约45％重量的糖衍生物; （iii）约10重量％至约15重量％氢化麦芽糖浆; 和（iv）约0％至约35％重量的多羟基醇。
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公开(公告)号：US5670163A
公开(公告)日：1997-09-23
申请号：US432805
申请日：1995-05-02
申请人： Robert C. Cuca , Keith S. Lienhop , Thomas Charles Riley, Jr. , Mitchell I. Kirschner , R. Saul Levinson
发明人： Robert C. Cuca , Keith S. Lienhop , Thomas Charles Riley, Jr. , Mitchell I. Kirschner , R. Saul Levinson
CPC分类号： A61K9/006 , A61K9/0056 , A61K9/0058 , A61K9/0065
摘要： A bioadherent, orally ingestible system, which comprises: a water-in-oil emulsion system having at least two phases, one phase comprises from about 75% to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about 1% by volume of an external hydrophobic phase, wherein the external hydrophobic phase comprises two components, one component being about 3% to about 97% by volume of the hydrophobic phase of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than about 10.
摘要翻译： 生物相容的口服摄取系统，其包含：具有至少两相的油包水乳液体系，一相包含约75体积％至约99体积％的内部亲水相，另一相包含约25 ％至约1体积％的外部疏水相，其中外部疏水相包含两种组分，一种组分为疏水相的疏水性油的约3％至约97体积％，另一种为约97％ 约3％HLB值小于约10的乳化剂。
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公开(公告)号：US08859011B2
公开(公告)日：2014-10-14
申请号：US11746832
申请日：2007-05-10
CPC分类号： A61K9/2059 , A23L29/015 , A23L33/16 , A23P10/25 , A23V2002/00 , A61K9/16 , A61K9/2027 , A61K33/10 , Y10S514/96 , A23V2250/1578 , A23V2250/7106
摘要： Compositions comprising calcium carbonate and processes for making such compositions are provided. The invention provides a granulation comprising about 95% to about 99% by weight calcium carbonate, about 0.5% to about 5% by weight of a binder and about 0.03% to about 3% by weight of a porosity increasing agent. A pharmaceutical or nutritional composition prepared from such a granulation comprises about 90% to about 99% by weight calcium carbonate, about 0.03% to about 3% by weight of a porosity increasing agent, and about 1% to about 10% by weight of other excipients. The composition provides a smaller tablet than conventional calcium carbonate compositions, for improved ease of swallowing.
摘要翻译： 提供了包含碳酸钙的组合物及其制备方法。 本发明提供了一种颗粒，其包含约95重量％至约99重量％的碳酸钙，约0.5重量％至约5重量％的粘合剂和约0.03重量％至约3重量％的孔隙率增加剂。 由这种造粒剂制备的药物或营养组合物包含约90％至约99％重量的碳酸钙，约0.03％至约3％重量的孔隙率增加剂和约1％至约10％重量的其它 赋形剂。 组合物提供比常规碳酸钙组合物更小的片剂，以改善容易吞咽。
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公开(公告)号：US07687485B2
公开(公告)日：2010-03-30
申请号：US10106381
申请日：2002-03-27
IPC分类号： A61K31/56 , A61K31/44 , A61K31/335 , A61K31/34
CPC分类号： A61K45/06 , A23L33/12 , A23L33/15 , A23L33/16 , A23V2002/00 , Y10S514/899 , A23V2250/211 , A23V2250/70 , A23V2250/156 , A23V2250/1868 , A23V2250/1874 , A23V2250/1872 , A23V2250/71 , A23V2250/712 , A23V2250/708 , A23V2250/704 , A23V2250/1578 , A23V2250/1588 , A23V2250/1642 , A23V2250/1626 , A23V2250/18 , A23V2250/30 , A23V2250/1592 , A23V2250/161 , A23V2200/224 , A23V2250/5432
摘要： The present disclosure relates to novel compositions which provide improved nutritional support for premenopausal and menopausal women and/or relief from symptoms associated with menopause, as well as prophylactic effects, and methods for using same.
摘要翻译： 本公开涉及提供改善的对绝经前和绝经期妇女的营养支持和/或缓解与绝经相关的症状以及预防效果的新型组合物及其使用方法。
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公开(公告)号：US06258846B1
公开(公告)日：2001-07-10
申请号：US09323159
申请日：1999-06-01
IPC分类号： A61K3120
CPC分类号： A23L33/12 , A23L33/10 , A23V2002/00 , Y10S514/87 , A23V2250/1872 , A23V2250/1874 , A23V2250/1882 , A23V2250/70 , A23V2250/156 , A23V2250/51084 , A23V2250/5118 , A23V2250/51088 , A23V2250/612 , A23V2250/1592
摘要： The present disclosure relates to novel nutritional compositions containing linoleic acid and/or linolenic acid which optimize child neurological development and provide improved nutritional support for women prior to and during lactation. The nutritional compositions are intended for use by women to optimize infant neurological development and provide improved nutritional support for women prior to, during and after lactation.
摘要翻译： 本公开涉及包含亚油酸和/或亚麻酸的新型营养组合物，其优化儿童神经发育并且在哺乳期间和哺乳期间为女性提供改善的营养支持。 营养组合物旨在供妇女使用以优化婴儿神经发育，并在哺乳期间，期间和之后为女性提供改善的营养支持。
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公开(公告)号：US5648093A
公开(公告)日：1997-07-15
申请号：US447253
申请日：1995-05-22
IPC分类号： A23L27/00 , A61K8/02 , A61K8/04 , A61K8/34 , A61K8/44 , A61K8/60 , A61K8/65 , A61K8/81 , A61K8/92 , A61K9/10 , A61K9/20 , A61K47/16 , A61K47/42 , A61Q19/00 , F26B5/00 , A61K9/14
CPC分类号： A61K8/0241 , A23L27/70 , A61K8/0208 , A61K8/34 , A61K8/44 , A61K8/60 , A61K8/65 , A61K8/8176 , A61K8/922 , A61K9/2095 , A61Q19/00 , F26B5/00 , A61K2800/56
摘要： A fast dissolving, solid dosage form defined by a matrix containing gelatin, pectin and/or soy fiber protein and one or more amino acids having from about 2 to 12 carbon atoms is disclosed.
摘要翻译： 公开了由含有明胶，果胶和/或大豆纤维蛋白质的基质和一个或多个具有约2至12个碳原子的氨基酸定义的快速溶解固体剂型。
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公开(公告)号：US5558880A
公开(公告)日：1996-09-24
申请号：US234295
申请日：1994-04-28
IPC分类号： A23L27/00 , A61K8/02 , A61K8/04 , A61K8/34 , A61K8/44 , A61K8/60 , A61K8/65 , A61K8/81 , A61K8/92 , A61K9/10 , A61K9/20 , A61K47/16 , A61K47/42 , A61Q19/00 , F26B5/00 , A61K9/14
CPC分类号： A61K8/0241 , A23L27/70 , A61K8/0208 , A61K8/34 , A61K8/44 , A61K8/60 , A61K8/65 , A61K8/8176 , A61K8/922 , A61K9/2095 , A61Q19/00 , F26B5/00 , A61K2800/56
摘要： A fast dissolving, solid dosage form defined by a matrix containing gelatin, pectin and/or soy fiber protein and one or more amino acids having from about 2 to 12 carbon atoms is disclosed.
摘要翻译： 公开了由含有明胶，果胶和/或大豆纤维蛋白质的基质和一个或多个具有约2至12个碳原子的氨基酸定义的快速溶解固体剂型。
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