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11.发明授权System and method for detecting respiratory insufficiency in the breathing of a subject 有权用于检测受试者呼吸的呼吸功能不全的系统和方法公开(公告)号：US08660971B2
公开(公告)日：2014-02-25
申请号：US13121002
申请日：2009-10-09
申请人： Joseph Allen Orr
发明人： Joseph Allen Orr
摘要： Respiratory insufficiency is detected by classifying preliminary breaths identified through a capnogram as being valid or artifact. Individual breaths are classified as being valid or artifact by determining values of a plurality of breathing parameters for a given breath, inferring a value for a key parameter from the determined values for the plurality of breathing parameters, and comparing the inferred value for the key parameter to a predetermined threshold.
摘要翻译： 通过将通过呼吸记录识别的初步呼吸分类为有效或伪像来检测呼吸功能不全。 通过确定用于给定呼吸的多个呼吸参数的值，将各个呼吸分类为有效或伪像，从多个呼吸参数的确定值推断关键参数的值，以及比较关键参数的推断值 达到预定阈值。
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公开(公告)号：US20120215125A1
公开(公告)日：2012-08-23
申请号：US13504758
申请日：2010-10-11
IPC分类号： A61B5/097
CPC分类号： A61M16/00 , A61B5/0816 , A61B5/082 , A61M16/0051 , A61M16/024 , A61M16/085 , A61M2016/0021 , A61M2016/0027 , G01N33/497
摘要： Sidestream sampling of gas to determine information related to the composition of gas at or near the airway of a subject is implemented. From such information one or more breathing parameters of subject 12 (e.g., respiratory rate, end-tidal CO2, etc.) are determined, respiratory events (e.g., obstructions, apneas, etc.) are identified, equipment malfunction and/or misuse is identified, and/or functions are performed. To improve the accuracy of one or more of these determinations, information related to pressure at or near the airway of subject is implemented. This information may include detection of pressure at or near a sidestream sampling cell.
摘要翻译： 实施气体取样以确定与受试者气道处或附近气体组成有关的信息。 从这些信息中，确定受试者12的一个或多个呼吸参数（例如呼吸频率，潮气CO2等），识别呼吸事件（例如障碍物，呼吸暂停等），设备故障和/或误用 识别和/或功能。 为了提高这些测定中的一个或多个的准确性，实施与受试者的气道处或附近的压力有关的信息。 该信息可以包括检测侧流采样单元处或附近的压力。
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13.发明授权公开(公告)号：US10561339B2
公开(公告)日：2020-02-18
申请号：US13994545
申请日：2011-12-13
申请人： Joseph Allen Orr
发明人： Joseph Allen Orr
摘要： A system is configured to perform capnometry/capnography, and/or other compositional analysis on a non-invasively ventilated subject. As such, the system determines amounts of a molecular species of gas (e.g., carbon dioxide, oxygen, etc.) excreted by the subject on a per-breath basis. Determinations of amounts of the molecular species of gas excreted are adjusted to reflect amounts of the molecular species of gas leaked from the non-invasive interface used to communicate with the airway of the subject.
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公开(公告)号：US09907511B2
公开(公告)日：2018-03-06
申请号：US13993097
申请日：2011-12-05
CPC分类号： A61B5/7278 , A61B5/0816 , A61B5/082 , A61B5/0836
摘要： Breaths of a subject are identified based on the concentration of carbon dioxide at or near the airway of the subject. Troughs corresponding to inhalation are identified and plateaus corresponding to exhalation are identified. A breath is identified responsive to a trough being followed by a plateau.
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15.发明申请METHOD AND APPARATUS FOR MONITORING AND CONTROLLING A PRESSURE SUPPORT DEVICE 审中-公开用于监测和控制压力支持装置的方法和装置公开(公告)号：US20150173647A1
公开(公告)日：2015-06-25
申请号：US14241577
申请日：2012-09-14
IPC分类号： A61B5/08
CPC分类号： A61B5/082 , A61M16/024 , A61M16/12 , A61M16/161 , A61M16/202 , A61M2016/0027 , A61M2016/0033 , A61M2016/102 , A61M2205/3368 , A61M2209/02 , A61M2230/43 , G01N2033/0072 , G05D11/132 , Y10T137/2499 , Y10T137/2529 , Y10T137/2703 , Y10T137/87684
摘要： A system is configured to generate a pressurized flow of gas comprised of a first gas having a partial pressure that varies in a predetermined manner. This may be used, for example, to simulate a previous and/or theoretical respiratory gas flow that was produced (or could have been produced) by a subject. The system is configured to deliver the pressurized flow of gas to a testing system configured to measure the partial pressure the first gas in flows of gas. This may provide an opportunity to determine the response of individual testing systems to various clinical circumstances.
摘要翻译： 一种系统构造成产生由具有以预定方式变化的分压的第一气体构成的加压气体流。 这可以用于例如模拟由受试者产生（或可能已经产生）的先前和/或理论呼吸气流。 该系统被配置为将加压的气体流输送到被配置成测量气体流中的第一气体的分压的测试系统。 这可以提供一个机会来确定各个测试系统对各种临床环境的响应。
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16.发明申请SYSTEM FOR PROVIDING SUPPORT THERAPY WHILE DETERMINING CONCENTRATIONS OF A MOLECULAR GASEOUS EXPIRED BY A SUBJECT RECEIVING PRESSURE SUPPORT THERAPY 有权在确定接受压力支持治疗的受试者已过期的分子气体浓度时提供支持治疗的系统公开(公告)号：US20120234324A1
公开(公告)日：2012-09-20
申请号：US13513430
申请日：2010-11-23
申请人： Joseph Allen Orr
发明人： Joseph Allen Orr
IPC分类号： A61M16/00
CPC分类号： A61M16/00 , A61B5/082 , A61M16/024 , A61M2016/0015 , A61M2016/0021 , A61M2016/0024 , A61M2016/0027 , A61M2205/18 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2205/52 , A61M2205/582 , A61M2230/432
摘要： Pressure support therapy is provided to a subject. The effectiveness of the provided pressure support therapy is determined and/or the therapy is titrated based on determinations of the concentration of one or more gaseous molecular species in gas exhaled by the subject. The determinations of composition of gas exhaled by the subject are obtained from samples with relatively little distortion caused by dilution of expired gases from gases provided to the airway of the subject as part of the pressure support therapy.
摘要翻译： 对受试者提供压力支持治疗。 基于受试者呼出的气体中一种或多种气态分子物质的浓度的测定，确定所提供的压力支持治疗的有效性和/或滴定治疗。 由受试者呼出的气体的组成的测定是从作为压力支持治疗的一部分的从提供给受试者气道的气体的过期气体稀释引起的变形相对较小的样品获得的。
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公开(公告)号：US10987023B2
公开(公告)日：2021-04-27
申请号：US13993159
申请日：2011-12-09
摘要： A system is configured to determine one or more breathing parameters of a subject, such as one or both of end-tidal carbon dioxide concentration and/or breath rate. The system is configured to make a plurality of preliminary determinations of an individual breathing parameter according to a plurality of different algorithms. A final determination of the breathing parameter is obtained by selecting one of the preliminary determinations based on therapy parameters, gas parameters, and/or other parameters that impact the accuracy and/or precision of the different algorithms.
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公开(公告)号：US09446210B2
公开(公告)日：2016-09-20
申请号：US13504758
申请日：2010-10-11
IPC分类号： A61B5/08 , A61B5/097 , A61M16/00 , G01N33/497 , A61M16/08
CPC分类号： A61M16/00 , A61B5/0816 , A61B5/082 , A61M16/0051 , A61M16/024 , A61M16/085 , A61M2016/0021 , A61M2016/0027 , G01N33/497
摘要： Sidestream sampling of gas to determine information related to the composition of gas at or near the airway of a subject is implemented. From such information one or more breathing parameters of subject 12 (e.g., respiratory rate, end-tidal CO2, etc.) are determined, respiratory events (e.g., obstructions, apneas, etc.) are identified, equipment malfunction and/or misuse is identified, and/or functions are performed. To improve the accuracy of one or more of these determinations, information related to pressure at or near the airway of subject is implemented. This information may include detection of pressure at or near a sidestream sampling cell.
摘要翻译： 实施气体取样以确定与受试者气道处或附近气体组成有关的信息。 从这些信息中，确定受试者12的一个或多个呼吸参数（例如呼吸频率，潮气CO2等），识别呼吸事件（例如障碍物，呼吸暂停等），设备故障和/或误用 识别和/或功能。 为了提高这些测定中的一个或多个的准确性，实施与受试者的气道处或附近的压力有关的信息。 该信息可以包括检测侧流采样单元处或附近的压力。
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公开(公告)号：US20140216451A1
公开(公告)日：2014-08-07
申请号：US14241457
申请日：2012-09-10
CPC分类号： A61M16/0051 , A61M16/0003 , A61M16/021 , A61M16/0833 , A61M16/0858 , A61M16/0875 , A61M16/20 , A61M2016/0027 , A61M2016/0033 , A61M2016/0036 , A61M2016/103 , A61M2205/15 , A61M2205/3368 , A61M2205/52 , A61M2230/432 , G01L13/00 , G01M3/2846
摘要： Gas-pressure-based testing, in some embodiments, features a self-leak-testing module (120) that includes an internal sensor and is configured for measuring, using the sensor, gas leakage (179, 180) from a set of walls that defines respective gas passageways that both exist within the module and are incident to the gas pressure measured. One or more walls of the set may extend outside the module. The module can be configured for deciding, based on a result of the measuring, whether a magnitude of the leakage exceeds a predetermined threshold. A source for applying the pressure may be internal (138) or external (104, 132, 135). Gas pressure based pattern recognition can be used to identify, optionally during treatment and in real time, one or more leak sites responsible for the leakage. The module is implementable as a ventilation monitoring module that measures differential flow of a breathing circuit, the testing serving to prevent cross-contamination of patients.
摘要翻译： 在一些实施例中，基于气体压力的测试的特征在于包括内部传感器的自泄漏测试模块（120），并且被配置用于使用传感器来测量来自一组壁的气体泄漏（179,180） 限定了两个存在于模块内并且被测量的气体压力入射的气体通道。 组件的一个或多个壁可以延伸到模块外部。 模块可以被配置用于基于测量的结果来确定泄漏的大小是否超过预定阈值。 用于施加压力的源可以是内部（138）或外部（104,132,135）。 基于气体压力的模式识别可以用于在治疗期间和实时地识别负责泄漏的一个或多个泄漏部位。 该模块可实现作为通气监测模块，其测量呼吸回路的差异流量，该测试用于防止患者的交叉污染。
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20.发明申请SYSTEM AND METHOD FOR DETERMINING CARBON DIOXIDE EXCRETED DURING NON-INVASIVE VENTILATION 审中-公开用于确定非入网通风期间二氧化碳的系统和方法公开(公告)号：US20130267863A1
公开(公告)日：2013-10-10
申请号：US13994545
申请日：2011-12-13
申请人： Joseph Allen Orr
发明人： Joseph Allen Orr
CPC分类号： A61B5/082 , A61B5/0836 , A61B5/087 , A61B5/091 , A61B5/4836 , A61B5/6814 , A61B5/72 , A61M16/0066 , A61M16/0069 , A61M16/024 , A61M16/0434 , A61M16/0666 , A61M16/0875 , A61M16/20 , A61M2016/0036 , A61M2205/15 , A61M2205/3365 , A61M2230/432 , A61M2230/435
摘要： A system is configured to perform capnometry/capnography, and/or other compositional analysis on a non-invasively ventilated subject. As such, the system determines amounts of a molecular species of gas (e.g., carbon dioxide, oxygen, etc.) excreted by the subject on a per-breath basis. Determinations of amounts of the molecular species of gas excreted are adjusted to reflect amounts of the molecular species of gas leaked from the non-invasive interface used to communicate with the airway of the subject.
摘要翻译： 系统被配置为对非侵入性通风的受试者执行电泳法/二氧化物图和/或其他成分分析。 因此，该系统确定受试者每次呼吸基础排泄的气体分子种类（例如二氧化碳，氧气等）的量。 调节排出气体的分子种类的量的测定以反映从用于与受试者的气道连通的非侵入性界面泄漏的气体的分子种类的量。
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