利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

33 条记录 (耗时 0.024 秒)

    EGR-EGFR complex
    11.
    发明授权
    EGR-EGFR complex 失效
    EGF-EGFR复合物

    公开(公告)号：US07514240B2

    公开(公告)日：2009-04-07

    申请号：US10503486

    申请日：2002-09-12

    申请人： Shigeyuki Yokoyama ,  Hideo Ogiso ,  Mikako Shirouzu ,  Osamu Nureki ,  Ryuichiro Ishitani ,  Kazuki Saito

    发明人： Shigeyuki Yokoyama ,  Hideo Ogiso ,  Mikako Shirouzu ,  Osamu Nureki ,  Ryuichiro Ishitani ,  Kazuki Saito

    IPC分类号： C12P1/00 ,  C12P21/04 ,  C07K14/00 ,  A61K38/27 ,  G06F19/00

    CPC分类号： C07K16/2863 ,  A61K2039/505 ,  C07K14/485 ,  C07K14/71 ,  C07K16/22 ,  C07K2299/00 ,  C07K2317/32 ,  C07K2317/34

    摘要： The present invention relates to a crystal of a complex of an epidermal growth factor (EGF) and an epidermal growth factor receptor (EGFR), a crystal of a complex of EGFR and a substance regulating EGFR activity, structure coordinates of these crystals, a method for screening for the substance regulating EGFR activity, a method for designing the substance regulating EGFR activity, a method for designing an EGFR variant or an EGF variant, a method for producing an EGFR variant or an EGF variant and an EGF variant or an EGFR variant obtainable by such method, a method for designing an epitope using the structure coordinates of the EGF-EGFR complex, a method for producing an anti-EGFR antibody or an anti-EGF antibody and an antibody obtainable by such method, a polypeptide or a salt thereof comprising a region that forms an EGFR dimerization site, and the like.

    摘要翻译： 本发明涉及表皮生长因子（EGF）和表皮生长因子受体（EGFR）的复合物的晶体，EGFR复合物的结晶和调节EGFR活性的物质，这些晶体的结构坐标，方法 用于筛选调节EGFR活性的物质，设计调节EGFR活性的物质的方法，设计EGFR变体或EGF变体的方法，产生EGFR变体或EGF变体和EGF变体或EGFR变体的方法 可以通过这种方法获得使用EGF-EGFR复合物的结构座标设计表位的方法，抗EGFR抗体或抗EGF抗体的制备方法和可通过这种方法获得的抗体，多肽或盐 其包含形成EGFR二聚化位点的区域等。

    Electrical socket which can be reduced in operating force
    12.
    发明授权
    Electrical socket which can be reduced in operating force 失效

    公开(公告)号：US07287997B2

    公开(公告)日：2007-10-30

    申请号：US11788915

    申请日：2007-04-23

    申请人： Seiya Matsuo ,  Kazuki Saito

    发明人： Seiya Matsuo ,  Kazuki Saito

    IPC分类号： H01R13/62

    CPC分类号： H05K7/1069 ,  G01R1/0466 ,  G01R1/0483 ,  H01R13/193

    摘要： In an electrical socket including a base for receiving a connection object in a predetermined direction, a plurality of contacts are held by the base and adapted to be contacted with the connection object. A pusher is rotatably held by the base and has an acting portion and an operating portion which is adapted to be operated. The pusher is continuously urged by a spring so that the connection object is brought into press contact with the contact via the acting portion. A cover is coupled to the base to be movable in the predetermined direction. One of the cover and the operating portion has a contact surface faced to the other in the predetermined direction. The other of the cover and the operating portion has a roller adapted to roll on the contact surface following the movement of the cover.

    Connector allowing locking of connected state or non-connected state
    13.
    发明授权
    Connector allowing locking of connected state or non-connected state 有权
    连接器允许锁定连接状态或非连接状态

    公开(公告)号：US07214082B2

    公开(公告)日：2007-05-08

    申请号：US10549092

    申请日：2004-03-12

    申请人： Osamu Hashiguchi ,  Kazuki Saito ,  Toshiaki Ariyoshi ,  Masahiko Sato

    发明人： Osamu Hashiguchi ,  Kazuki Saito ,  Toshiaki Ariyoshi ,  Masahiko Sato

    IPC分类号： H01R13/62

    CPC分类号： G05G1/08 ,  H01R13/18

    摘要： A connector for switching between the states of the connection and non-connection to a mating connector by a cam mechanism (6) movably installed in insulators (2, 3), wherein the cam mechanism comprises a first cam (6a) and a second cam (6b). The first cam is rotatable about an axis, slidable between first and second positions in a direction parallel with the axis, and energized toward the first position by an elastic member (8). The second cam is rotated in conjunction with the first cam to provide either of the connected state and non-connected state according to a rotating angle. The first cam comprises a locked part (6a2) engaged with the lock part (3b3) of the insulator in the rotating direction thereof when positioned at the first position and disengaged from the lock part when positioned at the second position.

    摘要翻译： 一种用于通过可移动地安装在绝缘体（2,3）中的凸轮机构（6）在连接状态和不连接到配合连接器之间切换的连接器，其中所述凸轮机构包括第一凸轮（6a）和第二凸轮 凸轮（6 b）。 第一凸轮可绕轴线旋转，可在与轴线平行的方向上在第一和第二位置之间滑动，并且通过弹性构件（8）朝向第一位置被激励。 第二凸轮与第一凸轮一起旋转，以根据旋转角度提供连接状态和非连接状态。 第一凸轮包括当定位在第一位置时与绝缘体的锁定部分（3b 3）在其旋转方向上接合的锁定部分（6,2），并且当位于第二位置时与锁定部分脱离接合。

    Electrical angle connector of a printed circuit board type having a plurality of connecting conductive strips of a common length
    15.
    发明授权
    Electrical angle connector of a printed circuit board type having a plurality of connecting conductive strips of a common length 失效
    印刷电路板类型的电角度连接器具有多个公共长度的连接导电条

    公开(公告)号：US5522727A

    公开(公告)日：1996-06-04

    申请号：US307199

    申请日：1994-09-16

    申请人： Kazuki Saito ,  Takenori Kudo ,  Shoji Umesato ,  Masahiro Yamada

    发明人： Kazuki Saito ,  Takenori Kudo ,  Shoji Umesato ,  Masahiro Yamada

    IPC分类号： H01R13/719 ,  H01R24/00 ,  H05K1/14 ,  H05K3/36 ,  H01R23/70

    CPC分类号： H01R23/6873 ,  H01R12/724 ,  H05K1/14 ,  H05K3/366

    摘要： A right-angle electrical connector comprising a plurality of contacts supported on an insulator body, the contacts having a length equal to one another and having opposite ends projecting in different directions normal to each other and coming into contact with first and second connection objects, respectively, to be electrically connected by the connector. Each of the contacts comprises two portions extending in the different directions. The ratio of two portions of each one of contacts is different from that of the different one of contacts. In order to avoid production of various contacts which are different from one another in shape and dimension, the connector comprises a main element of an insulator substrate and conductive strip lines formed thereon, and contact elements like one another fixed to the insulator substrate to project from, and in directions normal to, adjacent side edges of the insulator substrate, respectively. The conductive strip lines have a length equal to each other and first and second ends near the adjacent side edges and are electrically connected to the contact elements. The contact elements are used for making connection with the first and the second connection objects.

    摘要翻译： 一种直角电连接器，包括支撑在绝缘体上的多个触点，所述触头具有彼此相等的长度，并且具有彼此垂直于彼此不同方向突出并且与第一和第二连接对象接触的相对端 通过连接器电连接。 每个触点包括沿不同方向延伸的两个部分。 每个触头的两个部分的比例不同于不同触点之间的比率。 为了避免在形状和尺寸上彼此不同的各种触头的制造，连接器包括绝缘体基板的主要元件和形成在其上的导电带状线，以及彼此固定到绝缘体基板上的接触元件，以从 ，并且分别在与绝缘体基板的相邻侧边缘垂直的方向上。 导电带状线具有彼此相等的长度，并且邻近相邻侧边缘的第一和第二端电连接到接触元件。 接触元件用于与第一和第二连接对象连接。

    Manufacturing control device
    16.
    发明授权
    Manufacturing control device 有权
    制造控制装置

    公开(公告)号：US08730036B2

    公开(公告)日：2014-05-20

    申请号：US11569821

    申请日：2005-06-08

    申请人： Shingo Tsujihama ,  Kazuki Saito

    发明人： Shingo Tsujihama ,  Kazuki Saito

    IPC分类号： G08B21/00 ,  B25B21/00

    CPC分类号： G05B19/41805 ,  G05B2219/31027 ,  G05B2219/45127 ,  G05B2219/45203 ,  Y02P90/04 ,  Y10T29/49764 ,  Y10T29/5303 ,  Y10T29/53061

    摘要： Errors in work in a bolt or nut tightening process are reduced to an extremely low level. Further, the process of the work is accurately recorded and quality of production processes is improved. A production management device receives information on a production instruction from a superordinate device, optically displays, according to the information, a socket to be selected for work to tighten a bolt or a nut, automatically recognizes a nut taken out from a socket holder, and alarms when the recognized socket and the displayed socket do not agree.

    摘要翻译： 在螺栓或螺母紧固过程中工作的错误降低到非常低的水平。 此外，准确记录工作过程，提高生产过程的质量。 生产管理装置从上级装置接收关于生产指示的信息，根据该信息光学地显示要选择的用于工作的插座以紧固螺栓或螺母，自动识别从插座座取出的螺母，以及 当识别的插座和显示的插座不一致时发出警报。

    Electrical socket which can be reduced in operating force
    19.
    发明申请
    Electrical socket which can be reduced in operating force 失效
    可减少操作力的电插座

    公开(公告)号：US20070197075A1

    公开(公告)日：2007-08-23

    申请号：US11788915

    申请日：2007-04-23

    申请人： Seiya Matsuo ,  Kazuki Saito

    发明人： Seiya Matsuo ,  Kazuki Saito

    IPC分类号： H01R11/22

    CPC分类号： H05K7/1069 ,  G01R1/0466 ,  G01R1/0483 ,  H01R13/193

    摘要： In an electrical socket including a base for receiving a connection object in a predetermined direction, a plurality of contacts are held by the base and adapted to be contacted with the connection object. A pusher is rotatably held by the base and has an acting portion and an operating portion which is adapted to be operated. The pusher is continuously urged by a spring so that the connection object is brought into press contact with the contact via the acting portion. A cover is coupled to the base to be movable in the predetermined direction. One of the cover and the operating portion has a contact surface faced to the other in the predetermined direction. The other of the cover and the operating portion has a roller adapted to roll on the contact surface following the movement of the cover.

    摘要翻译： 在包括用于在预定方向上接收连接对象的基座的电插座中，多个触点由基座保持并适于与连接对象接触。 推动器由基座可旋转地保持，并具有作用部分和适于操作的操作部分。 推动器被弹簧连续推动，使得连接对象通过作用部分与接触件压接。 盖子连接到基座以在预定方向上可移动。 盖和操作部中的一个具有在预定方向上彼此面对的接触表面。 盖和操作部分中的另一个具有适于在盖的移动之后在接触表面上滚动的辊。

    Electrical socket which can be reduced in operating force
    20.
    发明授权
    Electrical socket which can be reduced in operating force 失效

    公开(公告)号：US07247042B2

    公开(公告)日：2007-07-24

    申请号：US11512925

    申请日：2006-08-30

    申请人： Seiya Matsuo ,  Kazuki Saito

    发明人： Seiya Matsuo ,  Kazuki Saito

    IPC分类号： H01R13/62

    CPC分类号： H05K7/1069 ,  G01R1/0466 ,  G01R1/0483 ,  H01R13/193

    摘要： In an electrical socket including a base for receiving a connection object in a predetermined direction, a plurality of contacts are held by the base and adapted to be contacted with the connection object. A pusher is rotatably held by the base and has an acting portion and an operating portion which is adapted to be operated. The pusher is continuously urged by a spring so that the connection object is brought into press contact with the contact via the acting portion. A cover is coupled to the base to be movable in the predetermined direction. One of the cover and the operating portion has a contact surface faced to the other in the predetermined direction. The other of the cover and the operating portion has a roller adapted to roll on the contact surface following the movement of the cover.