摘要:
A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided.A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.
摘要:
2-Oxo-1,2-dihydro-1,8-naphthyridine derivatives characterized by bearing a specific substituent, —X—R6, at the 3-position and a cyclic substituent, R5, at the 4-position; or salts thereof. The derivatives and the salts are useful as drugs, particularly preventive or therapeutic agents for respiratory diseases related to PDE IV.
摘要:
A serine derivative represented by the general formula (I) ##STR1## (symbols in the formula represent the following meanings; X: a sulfur atom or an oxygen atom, Y: a nitrogen atom or CH, R.sup.1 and R.sup.2 : the same or different from each other and each represents a hydrogen atom, a lower alkyl group or a protecting group for the amino group, or R.sup.1 and R.sup.2 may be combined together to form a four- to nine-membered nitrogen-containing cycloalkyl group, R.sup.3 : a hydrogen atom, a carboxyl group, a protected carboxyl group, an aralkyl group, or a lower alkyl group unsubstituted or substituted with a hydroxyl group, R.sup.4 : a hydrogen atom or a hydroxyl group, R.sup.5 : a hydrogen atom or a lower alkyl group, A: a lower alkylene group, B: 1) a saturated or unsaturated four- to ten-membered nitrogen-containing cycloalkyl group unsubstituted or substituted with a lower alkyl group or an aralkyl group or 2) a bicyclic nitrogen-containing hydrocarbon ring radical resulting from the condensation of a four- to eight-membered nitrogen-containing cycloalkyl group with a benzene ring, and . . : a single or double bond) or a pharmaceutically acceptable salt thereof, which has an anti-PCP (phencyclidine) action and is useful as a psychotropic drug.
摘要:
A tubular material drawing apparatus for manufacturing precision tubes comprises a plug set device, provided to a back bench, for holding a plug rod in a horizontal state, a travel base to be movable backward with respect to the back bench in a horizontal direction, a holding mechanism, provided to the travel base and capable of holding a rear end portion of a tube element, for holding the rear end portion of the tube element and moving the tube element in a horizontal direction to fit the tube element on the plug rod upon movement of the travel base, a clamp, movably provided to the travel base in a horizontal direction, holding the rear end portion of the tube element and then bringing the rear end portion to the holding mechanism, a carriage guide horizontally extending, a carriage which is guided by the carriage guide and is movable forward, die provided between the back bench and the carriage, and a chuck portion, provided to the carriage and capable of holding a front end portion of the tube element. The chuck portion, die, and holding mechanism are arranged to be coaxially positioned, for holding the front end portion of the tube element while the holding mechanism holds the front end portion of the tube element in which the plug rod is inserted, and while the carriage is moved forward, thereby allowing the die to draw the tube element.
摘要:
A composite speaker is provided capable of obtaining larger sound output than that of a conventional flat panel speaker and flat speaker when input with an audio signal of the same strength. The composite speaker includes: one magnet or a plurality of magnets disposed at predetermined intervals to each other; a yoke for forming a magnetic circuit with a magnetic gap to the magnets; a voice coil disposed in a gap between the magnets and the yoke so as to interlink with the magnetic circuit; a diaphragm with the voice coil fixed to one face thereof; a frame that supports the diaphragm at peripheral edge portions of the diaphragm and houses the magnets and the yoke; a speaker base plate fixed to the frame at the side of the frame supporting the diaphragm or at the side of the frame opposite to the side supporting the diaphragm; and a phase rotation member configured by an elastic member provided between the speaker base plate and the yoke; wherein sound is generated from both the diaphragm and the speaker base plate.
摘要:
A composite speaker is provided capable of obtaining larger sound output than that of a conventional flat panel speaker and flat speaker when input with an audio signal of the same strength. The composite speaker includes: one magnet or a plurality of magnets disposed at predetermined intervals to each other; a yoke for forming a magnetic circuit with a magnetic gap to the magnets; a voice coil disposed in a gap between the magnets and the yoke so as to interlink with the magnetic circuit; a diaphragm with the voice coil fixed to one face thereof; a frame that supports the diaphragm at peripheral edge portions of the diaphragm and houses the magnets and the yoke; a speaker base plate fixed to the frame at the side of the frame supporting the diaphragm or at the side of the frame opposite to the side supporting the diaphragm; and a phase rotation member configured by an elastic member provided between the speaker base plate and the yoke; wherein sound is generated from both the diaphragm and the speaker base plate.
摘要:
A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided.A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.
摘要:
An image processing apparatus that includes: a job processor that processes a job for image data; a job management unit that manages execution of the processing of the job; a connector to which a plurality of charge management devices that charge for the processing of the job are connected; a charge management selector that selects one of the plurality of charge management devices to charge for the processing of the job, the selection is based on operating states of the plurality of the charge management devices and is maintained until the processing of the job is performed; and a storage unit that stores a result of the selection made by the charge management selector when the processing of the job is started.
摘要:
A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.
摘要:
A tubular material drawing apparatus for manufacturing precision tubes comprises a plug set device, provided to a back bench, for holding a plug rod in a horizontal state, a travel base to be movable backward with respect to the back bench in a horizontal direction, a holding mechanism, provided to the travel base and capable of holding a rear end portion of a tube element, for holding the rear end portion of the tube element and moving the tube element in a horizontal direction to fit the tube element on the plug rod upon movement of the travel base, a clamp, movably provided to the travel base in a horizontal direction, holding the rear end portion of the tube element and then bringing the rear end portion to the holding mechanism, a carriage guide horizontally extending, a carriage which is guided by the carriage guide and is movable forward, die provided between the back bench and the carriage, and a chuck portion, provided to the carriage and capable of holding a front end portion of the tube element. The chuck portion, die, and holding mechanism are arranged to be coaxially positioned, for holding the front end portion of the tube element while the holding mechanism holds the front end portion of the tube element in which the plug rod is inserted, and while the carriage is moved forward, thereby allowing the die to draw the tube element.