摘要:
There is disclosed an advantageous mixed acid anhydride production method of formula (1): R1C(O)OY(O)n(R2)p (1) wherein R1, R2 and Y denote the same as defined below, n and p denote an integer of 1 or 2, which is characterized by adding a carboxylic acid of formula (2); R1COOH (2) wherein R1 denotes a hydrogen atom, an optionally substituted alkyl group or the like, an organic base to a solution of a carboxylic acid activating agent of formula (3); (R2)pY(O)nX (3) wherein R2 denotes an optionally substituted aliphatic hydrocarbyl group or the like, Y denotes a carbon atom, a phosphorus atom, or a sulfur atom, and X denotes a chlorine atom or the like.
摘要:
A stamp making apparatus of the invention makes a stamp plate on a stamp material by applying light thereto through a draft sheet. The stamp making apparatus includes an attachment that can be attached to and removed from a predetermined position facing the draft sheet and has a mounting hole where a holder having a stamp material can be inserted into and removed from. A plurality of mounting holes are formed in the attachment so that the holders having various types and shapes can be inserted into and removed from directly or via an auxiliary attachment. Further, the attachment includes a first adjusting device, which moves the mounting hole in a longitudinal direction of the draft sheet (in the Y direction), and a second adjusting device, which moves the mounting hole in a lateral direction (in the X direction), so that the position of the mounting hole in the attachment can be finely adjusted.
摘要:
There is provided a compound of the formula[I]: wherein R represents a hydrogen atom or a protective group for a hydroxyl group; and A represents a hydrogen atom, a halogen atom or a group of the formula A1: Q represents Q3: when A represents a halogen atom or a protective group for a hydroyl group, A represents Q4: wherein R1 and R2 represent a hydrogen atom or a protective group for a hydroxyl group; and when A represents a hydrogen atom, Q is Q2:
摘要:
A Kir6.2 gene-defective, non-human mammal, a mouse in particular, its tissues and cells are provided, wherein the ATP-sensitive potassium channel Kir6.2 gene, one of the subunits of KATP channels essential for insulin secretion by pancreatic &bgr;-cells, is lost from one or both of the allelic loci.
摘要:
A process for producing toners for use in electrophotography which comprises: stirring a mixture of a radical polymerizable liquid monomer and carbon black in the presence of a peroxide polymerization initiator, thereby to disperse the carbon black uniformly and minutely in the monomer; adding an azobisnitrile polymerization initiator to the resultant monomer composition; suspension polymerizing the monomer in an aqueous medium; and recovering and drying the resultant spherical polymer particles.In a preferred process, the suspension polymerization is carried out in an aqueous medium which contains polyvinyl alcohol as a suspending agent, and after the polymerization, the polyvinyl alcohol remaining on the polymer particles is saponified or nitrated to produce a toner with a higher quality.
摘要:
A sigma-delta modulator includes a plurality of quantizers, an input path, a feedback path, a loop filter, a pre-filter, and a connection path. The plurality of quantizers are configured to produce a plurality of quantized signals. The input path is configured to lead an input signal to the plurality of quantizers. The feedback path is configured to feed back a feedback signal into the input path, and the feedback signal is produced by averaging the plurality of quantized signals. The loop filter is put on the input path before the plurality of quantizers, and the loop filter is configured to receive the input signal and the feedback signal. The pre-filter is configured to output a signal to a corresponding quantizer which is one of the plurality of quantizers.
摘要:
An analysis device includes: a separation cavity 18 for separating a test liquid into a solution component and a solid component by using a centrifugal force; a higher specific gravity component quantitative cavity 23 for holding a portion of the separated solid component which has been transferred; a sample solution overflow cavity 22 arranged between the higher specific gravity component quantitative cavity 23 and the separation cavity 18 and connected to a connecting channel 21 for transporting the sample liquid from the separation cavity 18; and a capillary cavity 19 formed in the separation cavity 18 for temporarily holding a separated solution component (blood plasma) in the separation cavity 18. A blood plasma component 57a remaining in the separation cavity 18 is trapped by the capillary cavity 19.
摘要:
A compact flow-through NMR analyzer with high NMR signal detection sensitivity is provided. The flow-through NMR analyzer comprises: a solution feeding pipe 18 for flowing a sample fed from a solution feeding pump 6; a superconducting magnet 7 that encloses a housing space, which is surrounded by a side wall of the solution feeding pipe 18, around an axis of the solution feeding pipe 18 such that a static magnetic field is generated along the axis of the solution feeding pipe 18; a vacuum container 12 which houses the superconducting magnet 7 in a cooled state and which encloses the housing space around the axis of the solution feeding pipe 18; and an RF coil 22 which applies high-frequency electromagnetic waves to the sample inside the housing space and which detects an NMR signal from the sample. The RF coil 22 is integrally formed with the side wall of the solution feeding pipe 18 in a region of the solution feeding pipe 18 that is enclosed by the superconducting magnet 7 and the magnetic field correcting coil 4c.
摘要:
An end mill including multiple spiral flutes in a helical shape around an axis that are formed in a periphery of the top portion of an end mill body which rotates on the axis. Cutting edges are formed at peripheral side ridge portions of wall surfaces of the flutes facing a front side in an end mill rotating direction. Honing is applied along each peripheral cutting edge such that the cutting edge has a variable honing width in the direction of the axis.
摘要:
The present invention aims to provide a practical process for preparing amine compounds through a generalized highly-diastereoselective reductive amination reaction. The present invention relates to a process for diastereoselectively preparing an amine compound using a catalyst employed in a reductive amination reaction, comprising a specific organometallic compound represented by the following general formula (1):