公开(公告)号：US06927290B2

公开(公告)日：2005-08-09

申请号：US10841644

申请日：2004-05-10

申请人： Takashi Miki ,  Hideki Ushio ,  Isao Kurimoto

发明人： Takashi Miki ,  Hideki Ushio ,  Isao Kurimoto

IPC分类号： A61K38/00 ,  C07C269/06 ,  C07C271/22 ,  C07D277/46 ,  C07F9/09 ,  C07F9/32 ,  C07K5/06 ,  C07D203/04 ,  C07C231/00 ,  C07D203/16

CPC分类号： C07K5/06026 ,  A61K38/00 ,  C07C269/06 ,  C07D277/46 ,  C07F9/096 ,  C07F9/3294 ,  C07C271/22

摘要： There is disclosed an advantageous mixed acid anhydride production method of formula (1): R1C(O)OY(O)n(R2)p  (1) wherein R1, R2 and Y denote the same as defined below, n and p denote an integer of 1 or 2, which is characterized by adding a carboxylic acid of formula (2); R1COOH  (2) wherein R1 denotes a hydrogen atom, an optionally substituted alkyl group or the like, an organic base to a solution of a carboxylic acid activating agent of formula (3); (R2)pY(O)nX  (3) wherein R2 denotes an optionally substituted aliphatic hydrocarbyl group or the like, Y denotes a carbon atom, a phosphorus atom, or a sulfur atom, and X denotes a chlorine atom or the like.

摘要翻译： 公开了式（1）的有利的混合酸酐生产方法：<？在线公式描述=“在线公式”end =“lead”→> R 1（O （O）（O）n（R 2）p（1）<？in-line-formula description =“In-line Formulas” 其中R 1，R 2和Y表示与下面定义的相同，n和p表示1或2的整数，其特征在于 通过加入式（2）的羧酸; <？in-line-formula description =“In-line Formulas”end =“lead”？> R＆lt; 1＆gt; COOH（2）<？in-line-formula description =“In-line Formulas” 其中R 1表示氢原子，任选取代的烷基等，式（3）的羧酸活化剂的溶液的有机碱; （？2 formulas <<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<< 其中R 2表示任选取代的脂族烃基等，其中R 2表示任选取代的脂族烃基等， Y表示碳原子，磷原子或硫原子，X表示氯原子等。

公开(公告)号：US06753431B2

公开(公告)日：2004-06-22

申请号：US09870676

申请日：2001-06-01

申请人： Takashi Miki ,  Hideki Ushio ,  Isao Kurimoto

发明人： Takashi Miki ,  Hideki Ushio ,  Isao Kurimoto

IPC分类号： C07D21122

CPC分类号： C07K5/06026 ,  A61K38/00 ,  C07C269/06 ,  C07D277/46 ,  C07F9/096 ,  C07F9/3294 ,  C07C271/22

摘要： There is disclosed an advantageous mixed acid anhydride production method of formula (1): R1C(O)OY(O)n(R2)p  (1) wherein R1, R2 and Y denote the same as defined below, n and p denote an integer of 1 or 2, which is characterized by adding a carboxylic acid of formula (2); R1COOH  (2) wherein R1 denotes a hydrogen atom, an optionally substituted alkyl group or the like, an organic base to a solution of a carboxylic acid activating agent of formula (3); (R2)pY(O)nX  (3) wherein R2 denotes an optionally substituted aliphatic hydrocarbyl group or the like, Y denotes a carbon atom, a phosphorus atom, or a sulfur atom, and X denotes a chlorine atom or the like.

摘要翻译： 公开了式（1）的有利的混合酸酐的制备方法：其中R 1，R 2和Y表示与下面定义的相同，n和p表示1或2的整数，其特征在于 加入式（2）的羧酸;其中R 1表示氢原子，任选取代的烷基等，式（3）的羧酸活化剂的溶液中的有机碱：其中R 1， 2>表示任选取代的脂族烃基等，Y表示碳原子，磷原子或硫原子，X表示氯原子等。

公开(公告)号：US08785651B2

公开(公告)日：2014-07-22

申请号：US13142536

申请日：2009-03-24

申请人： Takashi Miki ,  Yasuharu Shimasaki ,  Srinivasan Babu ,  Zhigang Cheng ,  Mark E. Reynolds ,  Qingping Tian

发明人： Takashi Miki ,  Yasuharu Shimasaki ,  Srinivasan Babu ,  Zhigang Cheng ,  Mark E. Reynolds ,  Qingping Tian

IPC分类号： C07F5/04 ,  C07F5/02

CPC分类号： C07F5/025

摘要： The present invention relates to a method for manufacturing a boronic acid ester compound, characterized by reacting an aryl halide compound and a diboron ester compound in the presence of a nitrogen-containing organic base, a nickel catalyst, a phosphine compound and a solvent. According to the manufacturing method of the present invention, even if a nickel catalyst is used as the catalyst, a desired boronic acid ester compound can be obtained in a sufficiently high yield. Furthermore, even if aryl chloride or aryl bromide having relatively low price and low reactivity, was used as the aryl halide compound, a desired boronic acid ester compound can be obtained in a sufficiently high yield.

摘要翻译： 硼酸酯化合物的制造方法技术领域本发明涉及硼酸酯化合物的制造方法，其特征在于，在含氮有机碱，镍催化剂，膦化合物和溶剂的存在下，使芳基卤化合物与二硼酸酯化合物反应。 根据本发明的制造方法，即使使用镍催化剂作为催化剂，也能以足够高的收率获得所需的硼酸酯化合物。 此外，即使使用价格低廉，反应性低的芳基氯或芳基溴作为芳基卤化合物，可以以足够高的收率得到所需的硼酸酯化合物。

公开(公告)号：US20130334041A1

公开(公告)日：2013-12-19

申请号：US14001954

申请日：2012-03-28

申请人： Reiko Kondo ,  Takashi Miki ,  Atsushi Watanabe

发明人： Reiko Kondo ,  Takashi Miki ,  Atsushi Watanabe

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/15126 ,  A61B5/157 ,  C12Q1/006 ,  C12Q1/54 ,  G01N33/4875 ,  G01N33/64 ,  G01N33/66 ,  G01N2333/904

摘要： The objective of the invention is to enhance measurement accuracy in a device for measuring a biological sample. To attain this objective, the invention is provided with a main case (2) having a sensor insertion section (1), a measurement section (7) connected to the sensor insertion section (1), a controller (8) connected to the measurement section (7), and a display (3) connected to the controller (8). An acceleration sensor (5) is furnished for detecting a shock applied to the sensor insertion section (1).

摘要翻译： 本发明的目的是提高用于测量生物样品的装置中的测量精度。 为了达到这个目的，本发明提供了一种具有传感器插入部分（1）的主壳体（2），连接到传感器插入部分（1）的测量部分（7），连接到测量装置 部分（7）和连接到控制器（8）的显示器（3）。 提供加速度传感器（5），用于检测施加到传感器插入部分（1）的冲击。

公开(公告)号：US20130009643A1

公开(公告)日：2013-01-10

申请号：US13636612

申请日：2011-03-25

申请人： Takashi Miki ,  Yasuaki Terao

发明人： Takashi Miki ,  Yasuaki Terao

IPC分类号： G01R33/341 ,  G01R33/30

CPC分类号： G01R33/307 ,  G01R33/34069 ,  G01R33/34092 ,  G01R33/3635 ,  G01R33/3804 ,  G01R33/3875 ,  G01R33/465

摘要： A compact NMR analyzer for clinical examinations which is suitable for use at medical facilities is provided. An NMR analyzer for clinical examinations 1 for analyzing a sample including a liquid component extracted from a human body, includes: a solution feeding pump 6 that feeds a sample; a solution feeding pipe 18 that receives the sample fed from the solution feeding pump 6; a superconducting magnet 7 that encloses the solution feeding pipe 18 around an axis thereof; a helium container 9 that houses the superconducting magnet 7 and liquid helium 8; a vacuum container 12 that has a vacuum chamber and that houses the helium container 9 inside the vacuum chamber; heat shields 10 and 11 that cover the helium container 9 in the vacuum container 12; and a recondensing unit 3 that recondenses helium vaporized inside the helium container 9 and that cools the heat shields 10 and 11.

摘要翻译： 提供了适用于医疗设施的临床检查的紧凑型NMR分析仪。 用于分析包括从人体提取的液体成分的样品的临床检查用NMR分析仪1包括：供给样品的溶液供给泵6; 接收从溶液供给泵6供给的样本的溶液供给管18; 围绕其轴线包围溶液供给管18的超导磁体7; 容纳超导磁体7和液氦8的氦容器9; 真空容器12，其具有真空室并且容纳真空室内的氦容器9; 覆盖真空容器12中的氦容器9的隔热罩10和11; 以及再冷凝单元3，其再凝结在氦容器9内蒸发的氦并且冷却隔热罩10和11。

公开(公告)号：US08204424B2

公开(公告)日：2012-06-19

申请号：US12518493

申请日：2007-11-08

申请人： Takashi Miki ,  Takayuki Nagase ,  Sadaharu Nakamura

发明人： Takashi Miki ,  Takayuki Nagase ,  Sadaharu Nakamura

IPC分类号： G03G21/00

CPC分类号： G03G21/0017 ,  B29C41/003 ,  B29C41/042 ,  B29C41/22 ,  B29L2031/32

摘要： The present invention provides a cleaning blade for an electrophotographic device, which, even when spherical (perfectly spherical or irregularly shaped), polymerized toner with a small particle diameter is used, can achieve sufficient abrasion resistance and sufficient cleaning ability (particularly cleaning ability under low-temperature and low-humidity conditions). The cleaning blade for an electrophotographic device includes an elastic rubber member; and a supporting member. The elastic rubber member has a double layer structure including an edge layer and a base layer. The edge layer is made of a material with a JIS-A hardness of 65° to 72° at 23° C. and a rebound resilience of 10 to 35%. The base layer is made of a material with a JIS-A hardness of 70° to 80° at 23° C. and a rebound resilience of 40 to 70%, the JIS-A hardness value being larger than the value of hardness of the edge layer.

摘要翻译： 本发明提供了一种用于电子照相装置的清洁刮板，即使使用具有小粒径的聚合调色剂的球形（完全球形或不规则形状），也可以获得足够的耐磨性和足够的清洁能力（特别是低的清洁能力 温度和低湿度条件）。 用于电子照相装置的清洁刮板包括弹性橡胶构件; 和支撑构件。 弹性橡胶构件具有包括边缘层和基底层的双层结构。 边缘层由23℃的JIS-A硬度为65〜72°，回弹性为10〜35％的材料制成。 基层由23℃的JIS-A硬度为70〜80度，回弹性为40〜70％的材料制成，JIS-A硬度值大于 边缘层。

公开(公告)号：US07753205B2

公开(公告)日：2010-07-13

申请号：US12077642

申请日：2008-03-20

申请人： Yasuhiro Shibata ,  Teruo Imamaki ,  Takashi Miki ,  Susumu Murata

发明人： Yasuhiro Shibata ,  Teruo Imamaki ,  Takashi Miki ,  Susumu Murata

IPC分类号： B65D73/00

CPC分类号： B65D75/22 ,  B65D75/5844 ,  B65D75/66 ,  Y10S229/926 ,  Y10S229/927

摘要： A packaging container includes a first clamshell half, a second clamshell half, a connecting portion that connects an edge of the first clamshell with an edge of the second clamshell half, a sealed portion that fastens the first clamshell and the second clamshell to each other, the sealed portion being located at the edge of the packaging container on a side opposite to the connecting portion, and a severed portion that is provided in at least one of the first clamshell and the second clamshell between the sealed portion and a packaged object, which is accommodated in a room created between the first clamshell and the second clamshell when the clamshell halves are fitted to each other, and that is severed off for opening the packaging container.

摘要翻译： 包装容器包括第一蛤壳半部，第二蛤壳半部，将第一蛤壳的边缘与第二蛤壳半部的边缘连接的连接部分，将第一蛤壳和第二蛤壳彼此紧固的密封部分， 所述密封部分位于所述包装容器的与所述连接部分相对的一侧的边缘处;以及切断部分，设置在所述密封部分和包装物体之间的所述第一蛤壳和所述第二蛤壳中的至少一个中， 被容纳在第一蛤壳和第二蛤壳之间产生的房间中，当蛤壳半部彼此相配时，被切断以打开包装容器。

公开(公告)号：US20100069683A1

公开(公告)日：2010-03-18

申请号：US12583943

申请日：2009-08-28

申请人： Takashi Miki ,  Junichi Hori ,  Toshihide Takemoto ,  Noriyuki Utsumi ,  Takeaki Katayama ,  Masahito Watanabe ,  Kunihiko Murata

发明人： Takashi Miki ,  Junichi Hori ,  Toshihide Takemoto ,  Noriyuki Utsumi ,  Takeaki Katayama ,  Masahito Watanabe ,  Kunihiko Murata

IPC分类号： C07C37/00

CPC分类号： C07B53/00 ,  B01J31/1805 ,  B01J31/2295 ,  B01J2231/643 ,  B01J2531/0238 ,  B01J2531/822 ,  B01J2531/827 ,  C07F17/02

摘要： The present invention provides an asymmetric reduction catalyst effective in preparing optically-active alcohol compounds having various functional groups, and a process for preparing optically-active alcohol compounds using said asymmetric reduction catalyst.The organic metal compound of the present invention is represented by the following general formula (1): wherein R1 and R2 may be mutually identical or different, and are an alkyl group, a phenyl group, a naphthyl group, a cycloalkyl group, or an alicyclic ring formed by binding R1 and R2, which may have a substituent; R3 is a hydrogen atom or an alkyl group; Cp is a cyclopentadienyl group, which may have a substituent, bound to M1 via a π bond; X1 is a halogen atom or a hydrido group; M1 is rhodium or iridium; and * denotes asymmetric carbon.

摘要翻译： 本发明提供了一种有效地制备具有各种官能团的光学活性醇化合物的不对称还原催化剂，以及使用该不对称还原催化剂制备光学活性醇化合物的方法。 本发明的有机金属化合物由以下通式（1）表示：其中R1和R2可以相同或不同，为烷基，苯基，萘基，环烷基或 通过结合可以具有取代基的R 1和R 2形成的脂环; R3是氢原子或烷基; Cp是可以具有取代基的环戊二烯基，其通过a和p结合到M1; 键; X1是卤原子或氢环; M1是铑或铱; 和*表示不对称碳。

公开(公告)号：US07388769B2

公开(公告)日：2008-06-17

申请号：US11503956

申请日：2006-08-15

申请人： Takashi Miki

发明人： Takashi Miki

IPC分类号： G11C11/24

CPC分类号： G11C11/22 ,  H01L27/11502 ,  H01L27/11507

摘要： A semiconductor memory device includes plural memory cells MC arranged in a matrix, plural bit lines BL and plural plate line voltage supply lines SCP which are arranged in a row direction, plural sense amplifier circuits SA which are arranged in a column direction and are electrically connected to the respective bit lines, plural plate line voltage supply circuits CPD which are arranged in the column direction and drive the plate line voltage supply lines SCP, and means for electrically connecting the plate line voltage supply lines SCP with the plural plate lines CP, wherein the respective plate voltage supply lines SCP are electrically connected, at different positions on the same plate line CP, to the plate line CP.

摘要翻译： 半导体存储器件包括排列成矩阵的多个存储单元MC，排列成行方向的多个位线BL和多个板极电压供给线SCP，多个读出放大电路SA沿列方向配置并电连接 对各个位线，沿列方向配置并驱动板线电压供给线SCP的多个板线电压供给电路CPD，以及将板线电压供给线SCP与多个板线CP电连接的装置，其中， 各板电压供给线SCP在同一板线CP上的不同位置电连接到板线CP。

公开(公告)号：US07310954B2

公开(公告)日：2007-12-25

申请号：US11026153

申请日：2005-01-03

申请人： Takashi Miki

发明人： Takashi Miki

IPC分类号： F25B19/00 ,  F25B9/00 ,  F28F13/00 ,  F28F27/00

CPC分类号： C01B3/0089 ,  F25B2400/17 ,  F25D19/006 ,  F28F2013/008 ,  Y02E60/324

摘要： A cryogenic system includes a space formed between a cooling stage of a cryocooler unit and an element to be cooled, and a thermal joint placed in the space, wherein the thermal joint is composed of a substance that has a melting point higher than the cooling temperature of the element to be cooled and that is in a liquid or gaseous state at room temperature and atmospheric pressure. The cryogenic system can achieve reproducible and excellent thermal contact at a cooling stage without applying a large mechanical stress to a cryocooler unit structure.

摘要翻译： 低温系统包括在冷却器单元的冷却段和要冷却的元件之间形成的空间和放置在该空间中的热接头，其中，热接头由熔点高于冷却温度的物质构成 的待冷却元件，并且在室温和大气压下处于液态或气态。 低温系统可以在冷却阶段实现可重现和优异的热接触，而不会对低温冷却器单元结构施加大的机械应力。