公开(公告)号：US20130123598A1

公开(公告)日：2013-05-16

申请号：US13738621

申请日：2013-01-10

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores

IPC: A61B5/042 ,  A61B5/00 ,  A61B18/18 ,  A61B5/055

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.

Abstract translation: MRI兼容导管包括具有相对的远端和近端部分的细长柔性轴。 手柄附接到基端部，并且包括与轴远端部连通的致动器，该致动器构造成铰接轴远端部。 轴的远端部分可以包括消融尖端，并且包括邻近消融尖端定位的至少一个RF跟踪线圈，其被电连接到MRI扫描器。 当至少一个RF跟踪线圈暴露于MRI环境时，至少一个RF跟踪线圈电连接到减少耦合的电路。 每个RF跟踪线圈是1-10圈电磁线圈，并且沿着导管的纵向方向具有在约0.25mm和约4mm之间的长度。

公开(公告)号：US09891296B2

公开(公告)日：2018-02-13

申请号：US14468922

申请日：2014-08-26

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi

IPC: G01R33/28 ,  A61M5/158 ,  A61B10/02 ,  A61B5/055 ,  G01R33/34 ,  A61M39/02

CPC classification number: G01R33/286 ,  A61B5/055 ,  A61B10/0233 ,  A61M5/158 ,  A61M2039/025 ,  A61M2205/0211 ,  A61M2205/0227 ,  A61M2210/0687 ,  A61M2210/0693 ,  G01R33/287 ,  G01R33/34084

Abstract: Devices, kits, assemblies systems and methods for transferring fluid to or from a subject include an elongate guide cannula having opposing proximal and distal ends with an open axially extending lumen. The proximal end includes a connector. The devices also include an elongate needle having opposing proximal and distal ends, the needle having a connector that is configured to attach to the guide cannula connector and is attached to or attachable to a length of flexible tubing, wherein the elongate needle is configured to be slidably inserted into the guide cannula lumen so that the distal end of the needle extends out of the distal end of the distal end of the guide cannula a suitable distance.

公开(公告)号：US09630000B2

公开(公告)日：2017-04-25

申请号：US15012692

申请日：2016-02-01

Applicant: Boston Scientific Neuromodulation Corporation ,  MRI Interventions, Inc.

Inventor： Paul A. Bottomley ,  Parag V. Karmarkar ,  Justin M. Allen ,  William A. Edelstein ,  Peter Piferi ,  Brian Gore

IPC: A61N1/05 ,  A61N1/08 ,  A61N1/04 ,  B29C33/12 ,  G01N3/32 ,  B29L31/00

CPC classification number: A61N1/08 ,  A61N1/0488 ,  A61N1/05 ,  A61N1/086 ,  B29C33/126 ,  B29L2031/753 ,  G01N3/32 ,  Y10T29/49071

Abstract: MRI/RF compatible leads include at least one conductor, a respective conductor having at least one segment with a multi-layer stacked coil configuration. The lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related leads and methods of fabricating leads are also described.

公开(公告)号：US09572928B2

公开(公告)日：2017-02-21

申请号：US14204378

申请日：2014-03-11

Applicant: MRI Interventions, Inc.

Inventor： J. Michael Shifflette ,  Peter Piferi

IPC: A61M37/00 ,  A61M5/145 ,  A61M25/02

CPC classification number: A61M5/14593 ,  A61B90/11 ,  A61M5/14526 ,  A61M25/02 ,  A61M2005/14513

Abstract: A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, and a diaphragm that is in slideable sealing engagement with an inside wall of the tubular body. The diaphragm is movable in opposite first and second directions within the tubular body. A substance is contained within the tubular body between the diaphragm and the tubular body distal end, and a slave fluid is contained within the tubular body between the diaphragm and the tubular body proximal end. When pressure is exerted on the slave fluid, the slave fluid causes the diaphragm to move and eject the substance through the tubular body distal end.

Abstract translation: 物质输送装置包括具有相对的近端和远端的细长管状体，以及与管状体的内壁可滑动地密封接合的隔膜。 隔膜可在管状体内相对的第一和第二方向移动。 物质被包含在隔膜和管状体远端之间的管状体内，并且从动液容纳在隔膜和管状体近端之间的管状体内。 当从动液体施加压力时，从动液体使膜片移动并通过管状体远端排出物质。

公开(公告)号：US20160256069A1

公开(公告)日：2016-09-08

申请号：US15067615

申请日：2016-03-11

Applicant: MRI Interventions, Inc.

Inventor： Kimble Jenkins ,  Peter Piferi ,  Philip Bradley Hotte ,  Pavel Farberov ,  Timothy Neil Orr ,  Paul Arthur Geiger ,  David John Sayler

IPC: A61B5/055 ,  A61B90/00 ,  A61B34/00 ,  A61B5/00 ,  A61B34/10

CPC classification number: A61B34/74 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/0555 ,  A61B5/7435 ,  A61B34/10 ,  A61B34/25 ,  A61B90/11 ,  A61B90/14 ,  A61B90/361 ,  A61B90/37 ,  A61B90/96 ,  A61B2017/00212 ,  A61B2017/3407 ,  A61B2017/3409 ,  A61B2034/101 ,  A61B2034/107 ,  A61B2034/252 ,  A61B2034/254 ,  A61B2034/256 ,  A61B2090/103 ,  A61B2090/374 ,  A61B2090/3933 ,  A61B2090/3937 ,  A61B2090/395 ,  A61B2090/3954 ,  A61B2090/3983 ,  G01R33/286 ,  G01R33/3415 ,  G01R33/546

Abstract: Circuits and computer program products onboard and/or adapted to communicate with an scanner that electronically recognize predefined physical characteristics of the at least one tool to automatically segment image data provided by the scanner whereby the at least one tool constitutes a point of interface with the system. The circuits and computer program products are configured to provide a User Interface that defines workflow progression for an image guided surgical procedure and allows a user to select steps in the workflow, and generate multi-dimensional visualizations using the predefined data of the at least one tool and data from images of the patient in substantially real time during the surgical procedure.

Abstract translation: 板上和/或适于与扫描器通信的电路和计算机程序产品，其电子地识别所述至少一个工具的预定义的物理特性，以自动分割由扫描器提供的图像数据，由此所述至少一个工具构成与系统的接口点 。 电路和计算机程序产品被配置为提供定义用于图像引导的外科手术的工作流程的用户界面，并且允许用户选择工作流中的步骤，并使用至少一个工具的预定义数据生成多维可视化 以及在外科手术期间实质上实时地来自患者的图像的数据。

公开(公告)号：US20160220812A1

公开(公告)日：2016-08-04

申请号：US15012692

申请日：2016-02-01

Applicant: Boston Scientific Neuromodulation Corporation ,  MRI Interventions, Inc.

Inventor： Paul A. Bottomley ,  Parag V. Karmarkar ,  Justin M. Allen ,  William A. Edelstein ,  Peter Piferi ,  Brian Gore

IPC: A61N1/08 ,  A61N1/05

CPC classification number: A61N1/08 ,  A61N1/0488 ,  A61N1/05 ,  A61N1/086 ,  B29C33/126 ,  B29L2031/753 ,  G01N3/32 ,  Y10T29/49071

Abstract: MRI/RF compatible leads include at least one conductor, a respective conductor having at least one segment with a multi-layer stacked coil configuration. The lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related leads and methods of fabricating leads are also described.

Abstract translation: MRI / RF兼容引线包括至少一个导体，具有至少一个具有多层堆叠线圈配置的段的相应导体。 引线可以被配置为使得铅在局部组织中加热小于约10摄氏度（通常约5摄氏度或更低），或者当患者暴露于至少峰值输入SAR的目标RF频率时不加热局部组织 约4W / kg和/或全身平均SAR至少约2W / kg。 还描述了制造引线的相关引线和方法。

公开(公告)号：US09386941B2

公开(公告)日：2016-07-12

申请号：US14290051

申请日：2014-05-29

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Kamal Vij ,  Scott Arnold

IPC: A61B5/055 ,  A61B6/04

CPC classification number: A61B5/0555 ,  A61B6/0407

Abstract: Scanner Systems with table stabilizers for stabilizing patient support structures during a surgery include a stabilizer block that can cooperate with the gantry to structurally support a head end portion of the table to prevent undesired movement of the table under an end load.

Abstract translation: 具有用于在手术期间稳定患者支撑结构的台面稳定器的扫描仪系统包括可与机架配合的稳定器块，以结构地支撑工作台的头端部分，以防止工作台在端部负载下的不期望的移动。

公开(公告)号：US20150011869A1

公开(公告)日：2015-01-08

申请号：US14290051

申请日：2014-05-29

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Kamal Vij ,  Scott Arnold

IPC: A61B5/055 ,  A61B19/00 ,  A61B6/04

CPC classification number: A61B5/0555 ,  A61B6/0407

Abstract: Scanner Systems with table stabilizers for stabilizing patient support structures during a surgery include a stabilizer block that can cooperate with the gantry to structurally support a head end portion of the table to prevent undesired movement of the table under an end load.

Abstract translation: 具有用于在手术期间稳定患者支撑结构的台面稳定器的扫描仪系统包括可与机架配合的稳定器块，以结构地支撑工作台的头端部分，以防止工作台在端部负载下的不期望的移动。

公开(公告)号：US08886288B2

公开(公告)日：2014-11-11

申请号：US13738621

申请日：2013-01-10

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores

IPC: A61B5/05 ,  A61B5/06 ,  A61B5/055 ,  A61B5/00 ,  A61M25/01 ,  G01R33/28 ,  A61B5/042 ,  A61B18/18 ,  A61B5/053 ,  A61B18/02 ,  A61M5/00 ,  A61B19/00 ,  A61M29/00 ,  A61M25/00 ,  A61M25/06 ,  A61M25/09

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.

Abstract translation: MRI兼容导管包括具有相对的远端和近端部分的细长柔性轴。 手柄附接到基端部，并且包括与轴远端部连通的致动器，该致动器构造成铰接轴远端部。 轴的远端部分可以包括消融尖端，并且包括邻近消融尖端定位的至少一个RF跟踪线圈，其被电连接到MRI扫描器。 当至少一个RF跟踪线圈暴露于MRI环境时，至少一个RF跟踪线圈电连接到减少耦合的电路。 每个RF跟踪线圈是1-10圈电磁线圈，并且沿着导管的纵向方向具有在约0.25mm和约4mm之间的长度。

公开(公告)号：US20140046167A1

公开(公告)日：2014-02-13

申请号：US13772822

申请日：2013-02-21

Applicant: MRI INTERVENTIONS, INC.

Inventor： Kamal Vij ,  Peter Piferi ,  Richard James Kail

IPC: A61B5/00 ,  A61B5/055

CPC classification number: A61B5/7475 ,  A61B5/0046 ,  A61B5/055

Abstract: Fiber optic systems with an MR compatible mouse in an MR scanner room that connects to a fiber optic computer mouse interface that is attached to a fiber optic cable that connects to a USB port of a computer in the MR control room to allow the mouse in the MR scanner room to move a cursor on a monitor in communication with the computer in the control room of an MRI suite during an MRI guided surgical procedure. The fiber optic cable(s) can be routed though a conventional RF wall waveguide and avoids the need for additional holes in the penetration panel for connectors. The fiber optic systems can also include up converters and down converters for providing fiber optic video signals from cameras in the MR scanner room to display video signal on the monitor.

Abstract translation: 在MR扫描仪室中具有MR兼容鼠标的光纤系统，其连接到光纤计算机鼠标接口，该光纤连接到连​​接到MR控制室中的计算机的USB端口的光纤电缆，以允许鼠标在 MR扫描仪室在MRI指导手术过程中将光标移动到与MRI套件的控制室中的计算机通信的监视器上。 光纤电缆可以通过常规RF壁波导路由，并避免在用于连接器的穿透面板中需要额外的孔。 光纤系统还可以包括上变频器和下变频器，用于从MR扫描器室中的相机提供光纤视频信号，以在监视器上显示视频信号。