专利检索 ap:("Mahalaxmi Gita Bangera" OR "Roderick A. Hyde" OR "Muriel Y. Ishikawa" OR "Elizabeth A. Sweeney" OR "Lowell L. Wood, Jr." OR "Victoria Y. H. Wood") AND inv:"Roderick A. Hyde" 第 2 页

11.

发明授权
Tubular nanostructure targeted to cell membrane 有权
标题翻译：管状纳米结构靶向细胞膜

公开(公告)号：US09187330B2

公开(公告)日：2015-11-17

申请号：US12283908

申请日：2008-09-15

申请人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood

发明人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood

IPC分类号： B82Y40/00 , C01B31/02 , B82Y30/00

CPC分类号： C07K16/32 , A61K38/1703 , A61K38/1732 , A61K47/60 , A61K47/6871 , A61K47/6901 , B82Y5/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B21/0648 , C01B32/168 , C01B32/174 , C01B2202/02 , C01B2202/34 , C01B2202/36 , C01P2004/13 , Y02A50/473 , Y10S977/743 , Y10S977/75 , Y10S977/762 , Y10S977/788 , Y10S977/795 , Y10S977/848 , Y10S977/896 , Y10S977/915

摘要： Devices, compositions, and methods are described which provide a tubular nanostructure targeted to a lipid bilayer membrane. The targeted tubular nanostructure can have a surface region configured to pass through a lipid bilayer membrane of a cell, a hydrophobic surface region flanked by two hydrophilic surface regions configured to form a pore in a lipid bilayer membrane of a cellular organelle, and at least one ligand configured to bind one or more cognates on the lipid bilayer membrane of the cellular organelle. The target cell can be, for example, a tumor cell, an infected cell, or a diseased cell in a subject. The tubular nanostructure can form a pore in the lipid bilayer membrane of the cellular organelle, e.g., mitochondria, which can permit transit or translocation of at least one compound across the membrane and cause cell death of the target cell.

摘要翻译： 描述了提供靶向脂质双层膜的管状纳米结构的装置，组合物和方法。目标管状纳米结构可以具有被配置为穿过细胞的脂质双层膜的表面区域，侧壁有两个亲水性表面区域的疏水性表面区域，所述疏水性表面区域配置成在细胞器官细胞器的脂质双层膜中形成孔，以及至少一个配体被配置为结合细胞器的脂质双层膜上的一个或多个同源物。靶细胞可以是例如受试者中的肿瘤细胞，感染细胞或患病细胞。管状纳米结构可以在细胞器（例如线粒体）的脂质双层膜中形成孔，其可以允许至少一种化合物跨过膜的转运或易位并导致靶细胞的细胞死亡。

12.

发明授权
Health-related signaling via wearable items 有权

公开(公告)号：US08125331B2

公开(公告)日：2012-02-28

申请号：US12231053

申请日：2008-08-27

申请人： Paul G. Allen , Edward S. Boyden , Mahalaxmi Gita Bangera , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood

发明人： Paul G. Allen , Edward S. Boyden , Mahalaxmi Gita Bangera , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood

IPC分类号： G08B1/08

CPC分类号： A61B5/002 , A61B5/01 , A61B5/02007 , A61B5/02028 , A61B5/1113 , A61B5/411 , A61B5/681 , A61B5/6813 , A61B2560/0242 , A61B2560/0412 , G06F19/00 , G06F19/3418

摘要： Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.

13.

发明授权
Computational methods and systems for treatment in relation to modulation of CYP450 enzyme activity 失效
标题翻译：与CYP450酶活性调节有关的计算方法和系统

公开(公告)号：US08073632B2

公开(公告)日：2011-12-06

申请号：US12319153

申请日：2008-12-30

申请人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood

发明人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Elizabeth A. Sweeney , Lowell L. Wood, Jr. , Victoria Y. H. Wood

IPC分类号： G06F19/00

CPC分类号： G06Q50/22 , G06F19/00 , G06F19/3481 , Y02A90/22 , Y02A90/26

摘要： Methods and systems such as those described herein include accepting input, identifying CYP450-family enzymes, identifying at least one modulator of an enzyme, and communicating one or more treatments to a system user.

摘要翻译： 诸如本文所述的方法和系统包括接受输入，鉴定CYP450家族酶，鉴定至少一种酶的调节剂，以及将一种或多种治疗传递给系统用户。

14.

发明授权
Devices and methods for wearable injection guides 有权
标题翻译：可穿戴式注塑导轨的装置和方法

公开(公告)号：US09199044B2

公开(公告)日：2015-12-01

申请号：US13567921

申请日：2012-08-06

申请人： Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.

发明人： Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.

IPC分类号： A61M5/42 , A61M5/46 , A61B17/34 , G06F17/50 , A61B19/00

CPC分类号： A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086

摘要： Wearable injection guides and manufacture and use thereof are described, which include: a rigid material formed to substantially conform in shape to a topography of a body region of an individual, the rigid material substantially impenetrable to an injection needle, and the rigid material including one or more injection needle access regions arranged in a treatment pattern.

摘要翻译： 描述了可穿戴的注射引导件及其制造和使用，其包括：刚性材料，形成为基本上符合个体的身体区域的形状，刚性材料基本上不可渗透到注射针，并且刚性材料包括一个或更多的注射针入口区域以治疗图案排列。

15.

发明申请
SYSTEMS AND METHODS FOR WEARABLE INJECTION GUIDES 有权
标题翻译：用于注射指南的系统和方法

公开(公告)号：US20140039658A1

公开(公告)日：2014-02-06

申请号：US13568033

申请日：2012-08-06

申请人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, JR.

发明人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, JR.

IPC分类号： G06F17/50

CPC分类号： A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086

摘要： Systems and methods for wearable injection guides are described, which include: acquiring one or more digital images of a body region of an individual with at least one image capture device; creating a digitally rendered model of a wearable injection guide from the one or more digital images of the body region of the individual; adding one or more digitally rendered fiducials indicative of at least one treatment parameter to the digitally rendered model of the wearable injection guide; and forming the wearable injection guide from the digitally rendered model of the wearable injection guide, the formed wearable injection guide including one or more fiducials corresponding to the one or more digitally rendered fiducials on the digitally rendered model of the wearable injection guide.

摘要翻译： 描述了可穿戴式注射引导件的系统和方法，其包括：用至少一个图像捕获装置获取个体的身体区域的一个或多个数字图像; 从个体的身体区域的一个或多个数字图像创建可戴式注射引导件的数字渲染模型; 将指示至少一个治疗参数的一个或多个数字呈现的基准添加到所述可佩戴注射引导件的数字渲染模型; 以及从所述可穿戴式注射导向器的数字渲染模型形成所述可穿戴式注射导向器，所述可穿戴式注射引导件包括与所述可穿戴注射导向器的数字渲染模型上的所述一个或多个数字呈现的基准相对应的一个或多个基准。

16.

发明申请
DEVICES AND METHODS FOR WEARABLE INJECTION GUIDES 有权
标题翻译：装置和方法用于易磨损的注射指南

公开(公告)号：US20140039452A1

公开(公告)日：2014-02-06

申请号：US13567995

申请日：2012-08-06

申请人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, JR.

发明人： Mahalaxmi Gita Bangera , Edward S. Boyden , Hon Wah Chin , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, JR.

IPC分类号： A61M5/42

CPC分类号： A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086

摘要： Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter.

摘要翻译： 描述了可穿戴式注射引导件及其制造和使用，其包括：具有内表面和外表面的刚性可穿透针材料，内表面具有基本上符合个人身体区域的形貌的形状配合轮廓，所述外表面包括至少一个治疗参数的一个或多个基准指示。

17.

发明申请
Devices, Systems, and Methods for Automated Data Collection 有权

公开(公告)号：US20130297219A1

公开(公告)日：2013-11-07

申请号：US13463997

申请日：2012-05-04

申请人： Mahalaxmi Gita Bangera , Michael H. Baym , Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Elizabeth A. Sweeney , Lowell L. Wood, JR.

发明人： Mahalaxmi Gita Bangera , Michael H. Baym , Philip A. Eckhoff , Roderick A. Hyde , Muriel Y. Ishikawa , Elizabeth A. Sweeney , Lowell L. Wood, JR.

IPC分类号： G06F19/00

CPC分类号： G16H10/60 , G06F19/00 , G16H40/20 , G16H50/20 , G16H50/30

摘要： Embodiments disclosed herein relate to methods, devices, and computer systems thereof for automated data collection from a subject. In certain embodiments, one or more characteristics of a subject are sensed, and the subject is given a queue status indicator based on a comparison of the subject's one or more sensed characteristics with corresponding sensed characteristics from other subjects. In one embodiment, the subject is a healthcare worker and the system, methods, and devices are utilized to evaluate the overall health of the worker as part of the check-in process for work.

18.

发明申请
Material, system, and method that provide indication of a breach 有权
标题翻译：提供违规行为的材料，系统和方法

公开(公告)号：US20120135527A1

公开(公告)日：2012-05-31

申请号：US12927972

申请日：2010-11-29

申请人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Erez Lieberman , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, JR.

发明人： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Erez Lieberman , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, JR.

IPC分类号： G01N31/22 , G01N33/00

CPC分类号： G01N31/223 , D03D15/00 , D10B2401/20 , G08B21/245 , Y10T428/239

摘要： A multilayer material is described herein that includes a flexible inner layer and a flexible outer layer configured to enclose at least one signaling layer, the at least one signaling layer including at least one chemical compound. The multilayer material including the chemical compound within the at least one signaling layer is configured to release a gas-phase chemical compound to signal to a detector indicating a breach of the multilayer material. A multilayer material, a system, an article of clothing, or a method is described herein.

摘要翻译： 本文描述了一种多层材料，其包括柔性内层和柔性外层，其被配置为包围至少一个信号层，所述至少一个信号层包括至少一种化学化合物。包括至少一个信号层内的化合物的多层材料被配置为释放气相化合物以向检测器发出信号，指示破坏多层材料。本文描述了多层材料，系统，服装或方法。