摘要:
Bioassay equipment which prevents a variation in concentration of a medium or deposition/bonding of a substance in the medium to be caused by drying of the medium being stored or held in a reaction region providing an inter-substance interaction field. The bioassay equipment (2) comprises at least a means for supplying a medium containing a substance pertaining to the interaction to the reaction region R providing the field of inter-substance interaction such as hybridization, and a means for supplying required water automatically. The bioassay equipment (2) may comprises a means for automatically detecting the volume of the medium held in the reaction region R.
摘要:
In an exposure apparatus and an exposure method, a disc master to be used in the preparation of an optical disc is applied to an exposure device, making it possible to perform exposure on a disc master for an optical disc which is substantially improved in recording density. An exposure laser beam by SHG having a wavelength of 300 nm or less is modulated by a modulator, and applied by near field effect to a disc master by using an objective lens having a numerical aperture of 1.0 or more.
摘要:
A bioassay substrate high in integration amount, free in grouping of substances, low in cost, and the like are provided. Specifically, a bioassay substrate includes detection surfaces S on which detection substances can be solidified, the detection surfaces S is provided on a surface of a disk form substrate capable of reading out record information optically, and the detection surfaces S is provided in groove structures (pits) provided in the surface of the substrate radially as viewed on the upper side at predetermined intervals. A bioassay system using the bioassay substrate and a readout system are also provided.
摘要:
To provide a bioassay system or the like, which can solve the problem of allocating spaces above detecting sections and can also stabilize servo-controlled operation of a disk-shaped plate.Provided is a bioassay system (U) or the like, which is equipped with at least means for immobilizing a nucleotide chain, a peptide, a protein, a lipid, a low molecular-weight compound, a liposome or any other biological substance as a detection substance (D) in a detecting section (3), dropping a target-substance containing solution (S) onto the immobilized detection substance (D), and causing the detection substance (D) and the target substance (T) to interact with each other to prepare a reaction product (R); and means for condensing fluorescence (F), which has been emitted from the fluorescence-labeled substance (D) by irradiating excitation light (P) of a specific wavelength onto the reaction product (R), by a lens (5) arranged on a side of a back surface (102) of the reaction section (3) to determine an intensity of the fluorescence (F).
摘要:
A bioassay substrate and method thereof is provide. In the bioassay substrate, a sample solution is dripped onto a spot area to which a plurality of detection substances is fixed and an interaction between the detection substance and a target substance in the sample solution is detected by fluorescent intensity. The substrate includes: a predetermined number of the spot areas placed in a well arranged on the surface of the substrate; and a fine uneven structure continuously formed on a bottom surface configuring the spot areas.
摘要:
A method of producing a stamper, an optical recording medium produced by molding using the stamper, and a method of producing the same, wherein a base member having a mirror polished main surface and comprising silicon or glass is formed with a resist film; the resist film is exposed by a focused electron beam, an ultraviolet ray laser, etc. and developed so as to form a resist film of a pattern corresponding to relief shapes; the mirror surface of the base member is processed to relief shapes (projecting regions and recessed regions) by dry etching etc. using the obtained resist film as a mask so as to obtain a stamper; the obtained stamper is used for injection molding to form a medium substrate; and an optical recording multilayer film and a protective layer are formed to thereby produce an optical recording medium.
摘要:
A bioassay substrate (1) is flat and has a disc-shaped main side like an optical disc such as CD. The substrate (1) is rotatable about a central hole (2) formed therein. The substrate (1) has formed on the surface (1a) thereof a plurality of wells (8) where a probe-use DNA (detection-use nucleotide chain) and sample-use DNA (target nucleotide chain) react with each other for hybridization. The substrate (1) has a transparent electrode layer (4) formed as an underlying layer of the well (8). For hybridization, an external electrode (18) is placed in a position near the transparent electrode layer (4) from above the top surface (1a) of the substrate (1) to apply an AC power to between the transparent electrode layer (4) and external electrode (18) in order to apply an AC electric field perpendicularly to the substrate (1).
摘要:
An optical recording and reproduction method, optical pickup device, and optical recording and reproduction device are provided, in which an optical recording medium is irradiated with near-field light to perform recording and/or reproduction, and wherein two or more recording and reproduction beam spots are positioned in a recording and reproduction area between guide tracks on the optical recording medium to perform recording and/or reproduction, as a consequence of which application to near-field optical recording and reproduction is ideally performed, and high transfer rates become possible.
摘要:
A fine particle measuring method of performing optical measurement of fine particles introduced into a plurality of sample fluidic channels provided at predetermined distances on a substrate by scanning light to the sample fluidic channels is disclosed. The method includes: sequentially irradiating the light to at least two or more reference regions provided together with the sample fluidic channels; detecting a change of optical property occurring in the light due to the reference regions; and controlling timing of emission of the light to the sample fluidic channels.
摘要:
A substrate for bioassay comprises a substrate and a group of reaction regions serving as a field where interaction between substances proceeds and formed in the substrate, and a group of information pits used to obtain positional information of individual reaction regions and/or substance information used in the reaction regions. The group of reaction regions and the group of information pits are not formed in the same substrate surface. A bioassay apparatus using the substrate and a method for making the substrate are also provided.