公开(公告)号：US20220142513A1

公开(公告)日：2022-05-12

申请号：US17582903

申请日：2022-01-24

Applicant: Medtronic, Inc.

Inventor： Jianping Wu ,  Chih Lai ,  Dwight E. Nelson

IPC: A61B5/11 ,  A61B5/00 ,  G16H30/40

Abstract: Devices, systems, and techniques for analyzing video information to objectively identify patient behavior are disclosed. A system may analyze obtained video information of patient motion during a period of time to track one or more anatomical regions through a plurality of frames of the video information and calculate one or more movement parameters of the one or more anatomical regions. The system may also compare the one or more movement parameters to respective criteria for each of a plurality of predetermined patient behaviors and identify the patient behaviors that occurred during the period of time. In some examples, a device may control therapy delivery according to the identified patient behaviors and/or sensed parameters previously calibrated based on the identified patient behaviors.

公开(公告)号：US11083402B2

公开(公告)日：2021-08-10

申请号：US13955367

申请日：2013-07-31

Applicant: Medtronic, Inc.

Inventor： Dwight E. Nelson ,  Jianping Wu ,  Rahul Gupta ,  Yan Zhao

IPC: A61B5/00 ,  A61B5/374 ,  A61B5/316 ,  A61N1/36

Abstract: In some examples, a processor determines a patient state based on activity of a bioelectrical brain signal of a patient in one or more frequency sub-bands of a frequency band of interest. For example, a processor may determine a patient state based on the power level of a bioelectrical brain signal of the patient in one or more frequency sub-bands of a frequency band, or based on a spectral pattern of a bioelectrical brain signal in a frequency band, such as a shift in a power distribution between sub-bands, a change in the peak frequency within one or more sub-bands, a pattern of the power distribution over one or more frequency sub-bands, or a width or a variability of one or more sub-bands exhibiting a relatively high or low level of activity.

公开(公告)号：US10786674B2

公开(公告)日：2020-09-29

申请号：US15064337

申请日：2016-03-08

Applicant: Medtronic, Inc.

Inventor： Jianping Wu ,  Dwight E. Nelson ,  Gabriela C. Molnar

IPC: A61N1/36 ,  A61N1/05 ,  A61B5/00

Abstract: In some examples, a system may include a plurality of electrodes, electrical stimulation circuitry, and a controller. The controller may be configured to select one or more parameters of therapy to be delivered to a brain of a patient and to control the electrical stimulation circuitry to deliver the therapy to the brain of the patient based on the selected parameters and via a first one or more electrodes of the plurality of electrodes. The parameters may be defined based on a first plurality of electrical signals sensed at a plurality of different positions within the brain of the patient when electrical stimulation is not delivered at each of the positions and a second plurality of electrical signals sensed at each of the plurality of different positions within the brain of the patient in response to electrical stimulation delivered at each of the positions at a plurality of different intensities.

公开(公告)号：US10660699B2

公开(公告)日：2020-05-26

申请号：US14928464

申请日：2015-10-30

Applicant: Medtronic, Inc.

Inventor： Thaddeus S. Brink ,  Blake A. Hedstrom ,  Dwight E. Nelson ,  Ashish Singal ,  Xin Su

IPC: A61B18/14 ,  A61B5/20 ,  A61B5/0488 ,  A61B8/08 ,  A61B5/11 ,  A61B18/00 ,  A61B18/08 ,  A61B18/06 ,  A61B18/02 ,  A61B5/00

Abstract: The disclosure describes devices, systems, and techniques for identifying and treating bladder dysfunction. In one example, a method includes identifying one or more focal points at respective locations of bladder tissue of a bladder of a patient, the one or more focal points initiating coordinated contractions of a detrusor muscle. The method may also, or alternatively, include ablating, for each of the one or more focal points, a respective portion of the bladder tissue at the respective location of the focal point. Ablation of these targeted portions of the bladder tissue may reduce the coordinated contractions of the detrusor muscle and alleviate overactive bladder symptoms.

公开(公告)号：US20180243559A1

公开(公告)日：2018-08-30

申请号：US15967329

申请日：2018-04-30

Applicant: Medtronic, Inc.

Inventor： Thaddeus S. Brink ,  Xin Su ,  Dwight E. Nelson

IPC: A61N1/36

CPC classification number: A61N1/36007

Abstract: In one example, a method including generating electrical stimulation therapy with a frequency of approximately 500 hertz or greater, and controlling delivery of the electrical stimulation therapy to a patient via a medical device between at least one of contractions of a bladder or contractions of a bowel of a patient, wherein the electrical stimulation therapy comprises electrical stimulation therapy configured to inhibit contraction of the bladder when the electrical stimulation is delivered between the contractions of the bladder, wherein the electrical stimulation therapy comprises electrical stimulation therapy configured to inhibit contraction of the bowel when the electrical stimulation is delivered between the contractions of the bowel, and wherein at least one of the generating and controlling is performed via one or more processors.

公开(公告)号：US20170259064A1

公开(公告)日：2017-09-14

申请号：US15064337

申请日：2016-03-08

Applicant: Medtronic, Inc.

Inventor： Jianping Wu ,  Dwight E. Nelson ,  Gabriela C. Molnar

IPC: A61N1/36 ,  A61N1/05

Abstract: In some examples, a system may include a plurality of electrodes, electrical stimulation circuitry, and a controller. The controller may be configured to select one or more parameters of therapy to be delivered to a brain of a patient and to control the electrical stimulation circuitry to deliver the therapy to the brain of the patient based on the selected parameters and via a first one or more electrodes of the plurality of electrodes. The parameters may be defined based on a first plurality of electrical signals sensed at a plurality of different positions within the brain of the patient when electrical stimulation is not delivered at each of the positions and a second plurality of electrical signals sensed at each of the plurality of different positions within the brain of the patient in response to electrical stimulation delivered at each of the positions at a plurality of different intensities.

公开(公告)号：US20170239470A1

公开(公告)日：2017-08-24

申请号：US15436287

申请日：2017-02-17

Applicant: Medtronic, Inc.

Inventor： Xuan K. Wei ,  Ryan D. Willemsen ,  Dwight E. Nelson ,  Sudha B. Iyer ,  Kira Stolen ,  Xin Su

IPC: A61N1/36 ,  A61N1/05 ,  A61N1/372

CPC classification number: A61N1/36007 ,  A61N1/0514 ,  A61N1/36132 ,  A61N1/36135 ,  A61N1/3614 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/37247

Abstract: In some examples, a technique for delivering electrical stimulation therapy to a patient includes determining, by processing circuitry, one or more cycle settings associated with delivery of the electrical stimulation therapy, determining, by the processing circuitry, a cycle time period associated with each cycle setting, and delivering, by a medical device, electrical stimulation therapy based on the determined cycle settings and the determined cycle time periods. Each cycle setting may define an on-cycle, during which electrical stimulation is delivered, and an off-cycle, during which electrical stimulation is not delivered. The technique further may include delivering electrical stimulation to the patient to provide one or more reminders to the patient, such as a reminder to void or a reminder of the existence of electrical stimulation.

公开(公告)号：US20170065821A1

公开(公告)日：2017-03-09

申请号：US15256242

申请日：2016-09-02

Applicant: Medtronic, Inc.

Inventor： Thaddeus S. Brink ,  Dwight E. Nelson ,  Xin Su ,  Lance Zirpel

IPC: A61N1/36 ,  A61B5/00 ,  A61B5/0488 ,  A61B5/11 ,  A61B5/20 ,  A61B5/053

Abstract: Devices, systems, and methods may manage therapy delivery to a patient based on one or more physiological markers. In some examples, a method includes detecting a physiological marker that occurs prior in time to a dysfunctional phase of a physiological cycle, wherein a dysfunctional state of the physiological cycle occurs during the dysfunctional phase without treatment, responsive to detecting the physiological marker, initiating a first phase of the physiological cycle having a duration of time. The method may also include, responsive to the first phase elapsing, controlling a therapy delivery module to deliver neurostimulation therapy during a second phase that begins prior to the dysfunctional phase, wherein the neurostimulation therapy is configured to treat the dysfunctional state.

Abstract translation: 设备，系统和方法可以基于一个或多个生理学标记来管理对患者的治疗递送。 在一些实例中，一种方法包括检测在时间上发生在生理周期的功能失调阶段之前的生理标志物，其中生理循环的功能失调状态在没有治疗的功能障碍阶段期间发生，响应于检测生理学标志，发起 生理周期的第一阶段具有持续时间。 所述方法还可以包括响应于第一阶段过去，控制治疗递送模块在开始功能失调阶段之前的第二阶段期间递送神经刺激疗法，其中神经刺激疗法被配置为治疗功能障碍状态。

公开(公告)号：US08954152B2

公开(公告)日：2015-02-10

申请号：US13892401

申请日：2013-05-13

Applicant: Medtronic, Inc.

Inventor： Rahul Gupta ,  Gabriela C. Molnar ,  Dwight E. Nelson

IPC: A61N1/32 ,  A61N1/36 ,  A61N1/05 ,  A61B5/00

CPC classification number: A61N1/3606 ,  A61B5/4064 ,  A61B5/4082 ,  A61B5/4094 ,  A61B5/6868 ,  A61N1/0529 ,  A61N1/36025 ,  A61N1/36064 ,  A61N1/36067 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/36139 ,  A61N1/36167

Abstract: Methods and apparatuses are disclosed for potentiating a favorable brain state that is associated with relief in symptoms of a brain condition. Techniques include monitoring one or more brain signals and detecting an episode of a favorable brain state based on the one or more brain signals, the favorable brain state associated with a decrease in one or more symptoms of a brain condition of the patient. Then, in response to the detection of the favorable brain state episode, electrical stimulation that potentiates the favorable brain state is delivered to the brain of the patient, the electrical stimulation delivered within a window of time opened for detection of each favorable brain state episode.

Abstract translation: 公开了用于增强与大脑状​​况症状缓解相关的有利的脑状态的方法和装置。 技术包括基于一个或多个脑信号监测一个或多个脑信号和检测有利的脑状态的发作，所述脑信号与患者的脑部状况的一个或多个症状的减少有关的有利的脑状态。 然后，响应于有利的脑状态发作的检测，将有利的脑状态的电刺激递送到患者的大脑，在打开每个有利的脑状态发作的时间窗口内递送电刺激。

公开(公告)号：US20140371599A1

公开(公告)日：2014-12-18

申请号：US14104057

申请日：2013-12-12

Applicant: Medtronic, Inc.

Inventor： Jianping Wu ,  Chih Lai ,  Dwight E. Nelson

IPC: A61B5/00

CPC classification number: A61B5/0077 ,  A61B5/0022 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/08 ,  A61B5/1114 ,  A61B5/1124 ,  A61B5/1128 ,  A61B5/4082 ,  A61B5/4803 ,  A61B5/4809 ,  A61B5/4836 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/7264 ,  A61B5/743 ,  A61N1/36 ,  G06T7/254 ,  G06T7/262 ,  G06T2207/10016 ,  G06T2207/30196

Abstract: Devices, systems, and techniques for analyzing video information to objectively identify patient behavior are disclosed. A system may analyze obtained video information of patient motion during a period of time to track one or more anatomical regions through a plurality of frames of the video information and calculate one or more movement parameters of the one or more anatomical regions. The system may also compare the one or more movement parameters to respective criteria for each of a plurality of predetermined patient behaviors and identify the patient behaviors that occurred during the period of time. In some examples, a device may control therapy delivery according to the identified patient behaviors and/or sensed parameters previously calibrated based on the identified patient behaviors.

Abstract translation: 公开了用于分析视频信息以客观地识别患者行为的设备，系统和技术。 系统可以在一段时间内分析获得的患者运动的视频信息，以通过视频信息的多个帧跟踪一个或多个解剖区域，并且计算一个或多个解剖区域的一个或多个运动参数。 系统还可以将一个或多个运动参数与多个预定患者行为中的每一个的相应标准进行比较，并且识别在该时间段期间发生的患者行为。 在一些示例中，装置可以根据所识别的患者行为和/或基于所识别的患者行为预先校准的感测参数来控制治疗递送。