Stimulation induced neural response for parameter selection

    公开(公告)号:US11623096B2

    公开(公告)日:2023-04-11

    申请号:US16945624

    申请日:2020-07-31

    Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.

    DENOISING SENSED SIGNALS FROM ARTIFACTS FROM CARDIAC SIGNALS

    公开(公告)号:US20220287646A1

    公开(公告)日:2022-09-15

    申请号:US17690045

    申请日:2022-03-09

    Abstract: A method for artifact suppression in a sensed signal includes receiving the sensed signal sensed in a brain of a patient, wherein the sensed signal includes a neural signal and artifacts from a cardiac signal, decomposing the sensed signal into a plurality of components of the sensed signal, determining a first group of components, from the plurality of components, that are correlated with one another, determining an estimate of the cardiac signal based on the first group of components, wherein the estimate of the cardiac signal includes the cardiac signal and components of the neural signal, and generating a denoised neural signal based on the estimate of the cardiac signal and a second group of components of the plurality of components of the sensed signal, wherein the cardiac signal is suppressed in the denoised neural signal, and wherein the second group of components excludes the first group of components.

    STIMULATION INDUCED NEURAL RESPONSE FOR PARAMETER SELECTION

    公开(公告)号:US20220032063A1

    公开(公告)日:2022-02-03

    申请号:US16945624

    申请日:2020-07-31

    Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.

    Determination of therapy electrode locations relative to oscillatory sources within patient

    公开(公告)号:US11045652B2

    公开(公告)日:2021-06-29

    申请号:US16395320

    申请日:2019-04-26

    Abstract: Techniques are described determining electrodes that are proximate or distal to location of an oscillatory signal source in a patient based on current source densities (CSDs). Processing circuitry may determine, for one or more electrodes of a plurality of electrodes, respective time-varying measurements of CSDs, aggregate, for the one or more electrodes of the plurality electrodes, the respective time-varying measurements of the CSDs to generate respective average level values for the one or more electrodes of the plurality of electrodes, determine, for one or more electrodes of the plurality of electrodes, respective phase-magnitude representations of the time-varying measurements of the CSDs. The respective phase-magnitude representations are indicative of respective magnitudes and phases of a particular frequency component of respective time-varying measurements of the CSDs. The particular frequency component is a frequency component having a largest transform coefficient in a time-varying measurement of a CSD having a largest average level value.

    Stimulation induced neural response for parameter selection

    公开(公告)号:US12168133B2

    公开(公告)日:2024-12-17

    申请号:US18298179

    申请日:2023-04-10

    Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.

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