公开(公告)号：US20140012369A1

公开(公告)日：2014-01-09

申请号：US13969784

申请日：2013-08-19

Applicant: Medtronic, Inc.

Inventor： Robert Murry, III ,  Susheel Deshmukh ,  Padraig Savage ,  Matthew Rust

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2002/9517 ,  A61F2002/9534

Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.

Abstract translation: 用于经皮部署支架假体心脏瓣膜的输送装置。 该装置包括递送胶囊和再捕获护套。 胶囊被构造成压缩地保持假体。 重新捕获鞘包括具有多个周向间隔的流道和聚合物覆盖层的漏斗段。 流道附着在轴上，并终止于远端。 覆盖物围绕流道，并且结合到轴，但至少不是尖端。 漏斗段可以从正常状态转变成扩展状态，形成具有向远端增加的直径的漏斗形状，并且可自由转变回正常状态。 漏斗段有助于将胶囊滑动在假体的部分展开的区域上，作为重新捕获操作的一部分。 跑步者提供柱状强度，覆盖层控制漏斗段的形状。

公开(公告)号：US10321992B2

公开(公告)日：2019-06-18

申请号：US15012533

申请日：2016-02-01

Applicant: Medtronic, Inc.

Inventor： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

IPC: A61F2/24

Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

公开(公告)号：US10231832B2

公开(公告)日：2019-03-19

申请号：US15482032

申请日：2017-04-07

Applicant: Medtronic, Inc.

Inventor： Padraig Savage ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Michael Krivoruchko

IPC: A61F2/24

Abstract: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.

公开(公告)号：US08986375B2

公开(公告)日：2015-03-24

申请号：US13795066

申请日：2013-03-12

Applicant: Medtronic, Inc.

Inventor： Kshitija Garde ,  Philip Haarstad ,  Igor Kovalsky ,  Stephen Nash ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Jeffrey Sandstrom ,  Padraig Savage ,  William Steinberg

IPC: A61F2/24

CPC classification number: A61F2/2445 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2250/0069

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.

Abstract translation: 经导管瓣膜假体包括可扩张的管状支架，支架内的假体瓣膜，以及耦合到环绕支架并包围多个自膨胀支柱和环形密封膜的抗瓣膜泄漏部件。 每个支柱具有联接到支架的远端的第一端和未联接到支架的第二端。 每个反paravalvular泄漏组件可在压缩配置和部署配置之间移动。 在压缩构型中，每个支柱远离支架远端延伸。 在展开的构造中，每个支柱向近端延伸远离支架的远端。 在本发明的一个实施例中，所展开的支柱具有C形并且被扭曲，使得C形位于与支架的外表面基本上沿或相切的平面中。 在本发明的另一个实施例中，部署的支柱被卷起并且从支架的外表面径向延伸。

公开(公告)号：US08986372B2

公开(公告)日：2015-03-24

申请号：US13969784

申请日：2013-08-19

Applicant: Medtronic, Inc.

Inventor： Robert Murry, III ,  Susheel Deshmukh ,  Padraig Savage ,  Matthew Rust

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2002/9517 ,  A61F2002/9534

Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.

Abstract translation: 用于经皮部署支架假体心脏瓣膜的输送装置。 该装置包括递送胶囊和再捕获护套。 胶囊被构造成压缩地保持假体。 重新捕获鞘包括具有多个周向间隔的流道和聚合物覆盖层的漏斗段。 流道附着在轴上，并终止于远端。 覆盖物围绕流道，并且结合到轴，但至少不是尖端。 漏斗段可以从正常状态转变成扩展状态，形成具有向远端增加的直径的漏斗形状，并且可自由转变回正常状态。 漏斗段有助于将胶囊滑动在假体的部分展开的区域上，作为重新捕获操作的一部分。 跑步者提供柱状强度，覆盖层控制漏斗段的形状。

公开(公告)号：US20140222142A1

公开(公告)日：2014-08-07

申请号：US14175100

申请日：2014-02-07

Applicant: Medtronic, Inc.

Inventor： Igor Kovalsky ,  Cathleen Bergin ,  Marian Creaven ,  Joshua Dwork ,  Kshitija Garde ,  Daniel Glozman ,  Ilia Hariton ,  Pham Lo ,  Jason Quill ,  Jeffrey Sandstrom ,  Padraig Savage ,  Michael Schendel ,  Elizabeth Schotzko ,  Yossi Tuval ,  Nadav Yellin

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0036 ,  A61F2250/0071

Abstract: Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.

Abstract translation: 公开了包括具有流入部分，阀保持管状或中心部分和一对支撑臂的框架或支撑结构的心脏瓣膜假体。 流入部分从阀保持管状部分的第一端径向延伸，并且一对支撑臂沿圆周间隔开并且从阀保持管状部分的相对的第二端径向延伸。