Method for the preparation of low odor 2,3-dimercaptosuccinic acid
    12.
    发明授权
    Method for the preparation of low odor 2,3-dimercaptosuccinic acid 失效
    低气味2,3-二巯基琥珀酸的制备方法

    公开(公告)号:US5292943A

    公开(公告)日:1994-03-08

    申请号:US824640

    申请日:1992-01-23

    CPC分类号: C07C319/28

    摘要: A method for producing low odor meso-2,3-dimercaptosuccinic acid is provided whereby a meso-2,3-dimercaptosuccinic acid substrate is washed with an aqueous wash medium and subsequently dried, preferably at a temperature of less than 40.degree. C. and a low odor meso-2,3-dimercaptosuccinic acid is also provided by this invention.

    摘要翻译: 提供了一种生产低气味的内消旋-2,3-二巯基琥珀酸的方法,其中内消旋-2,3-二巯基琥珀酸底物用水性洗涤介质洗涤,随后干燥,优选在低于40℃的温度下, 本发明也提供了低气味的内消旋-2,3-二巯基琥珀酸。

    Skin care composition
    14.
    发明授权
    Skin care composition 失效
    护肤组合物

    公开(公告)号:US07396526B1

    公开(公告)日:2008-07-08

    申请号:US09565716

    申请日:2000-05-05

    IPC分类号: A61K31/74 A61K9/00 A61K8/02

    摘要: There are provided compositions which include a retinoid and preferably retinal; a dermatologically active acid; and a volatile base, such as ammonium hydroxide. Another embodiment of the invention includes compositions comprising a retinoid and preferably retinal; a dermatologically active acid; a volatile base; and a second neutralizing agent. There are also provided compositions which include a retinoid, a neutralized ammonium salt of a dermatologically active acid, and optionally a neutralized salt, other than ammonium salt, of an acid. Further provided are methods for reducing fine lines, wrinkles, skin roughness, and pore size and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.

    摘要翻译: 提供了包含类视黄醇并优选视黄醛的组合物; 皮肤病学活性的酸; 和挥发性碱,例如氢氧化铵。 本发明的另一个实施方案包括包含类视黄醇并优选视黄醛的组合物; 皮肤病学活性的酸; 挥发性碱 和第二中和剂。 还提供了组合物,其包含类视黄醇,皮肤病学活性酸的中和铵盐,以及任选的除铵盐之外的中和盐。 还提供了减少有需要的哺乳动物的细纹,皱纹,皮肤粗糙度和孔径以及增加皮肤表面的清晰度,细胞周转,皮肤光泽,皮肤光滑度,皮肤渗透或胶原蛋白合成的方法。 如上所述的组合物局部施用于动物的皮肤。

    Process for the preparation of 2,3-dimercaptosuccinic acid and its lower
alkyl esters
    17.
    发明授权
    Process for the preparation of 2,3-dimercaptosuccinic acid and its lower alkyl esters 失效
    制备2,3-二巯基琥珀酸及其低级烷基酯的方法

    公开(公告)号:US4550193A

    公开(公告)日:1985-10-29

    申请号:US385953

    申请日:1982-06-07

    IPC分类号: C07C149/20 C07C148/00

    CPC分类号: C07C323/00

    摘要: 2,3-dimercaptosuccinic acid and esters thereof are prepared by reacting sodium thiosulfate with acetylene dicarboxylic acid in the presence of a strong acid and subjecting the resulting alkylthiosulfate to an acid hydrolysis. The 2,3-dimercaptosuccinic acids and esters thereof are useful as an antidote for heavy metal poisoning.

    摘要翻译: 2,3-二巯基琥珀酸及其酯的制备方法是在强酸存在下使硫代硫酸钠与乙炔二羧酸反应,并使得到的烷基硫代硫酸盐进行酸水解。 2,3-二巯基琥珀酸及其酯可用作重金属中毒的解毒剂。