Process for producing diol and lactone and microorganisms capable of same
    11.
    发明授权
    Process for producing diol and lactone and microorganisms capable of same 失效
    生产能够相同的二醇和内酯和微生物的方法

    公开(公告)号:US4970163A

    公开(公告)日:1990-11-13

    申请号:US399826

    申请日:1989-08-28

    IPC分类号: C12P17/04

    摘要: Described is a microbilogical method for producing the lactone, sclareolide and a diol having the chemical structure: ##STR1## using sclareol having the structure: ##STR2## as a substrate and using one of the microorganisms: Cryptococcus albidus (saito [skinner var. albidus]), ATCC 20918Bensingtonia ciliata, ATCC 20919Cryptococcus laurentii, ATCC 20920Cryptococcus albidus, ATCC 20921.

    摘要翻译: 描述了一种用于生产具有以下化学结构的内酯,香紫苏内酯和二醇的微生物学方法:使用具有以下结构的香叶介体作为底物并使用其中一种微生物:白垩纪(Saito [skinner var。albidus ]),ATCC 20918 Bensingtonia ciliata,ATCC 20919月桂树隐球菌,ATCC 20920隐球菌,ATCC 20921。

    Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof
    15.
    发明授权
    Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof 有权
    用于高产量生产食品香料可接受的茉莉酸和茉莉酸甲酯的生物工艺,由此产生的新颖茉莉酸异构体及其用途

    公开(公告)号:US06458569B1

    公开(公告)日:2002-10-01

    申请号:US09935320

    申请日:2001-08-22

    IPC分类号: C12P1702

    摘要: Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the “cis” isomer defined according the structure: (wherein R is hydrogen or methyl) or at least 5% of the “cis” isomer defined according to the structure: (wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&agr;D20) of +58° are novel. Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&agr;D20) of +58° are also novel. The process of our invention comprises the cultivation under aerobic condition of one or more specific strain of Diplodia gossypina in a nutrient medium followed either by (1) isolation of the jasmonic acid product or (2) esterification of the jasmonic acid to form methyl jasmonate followed by the isolation of the methyl jasmonate and novel products produced by such process.

    摘要翻译: 描述了用于高产量生产食用香料可接受的茉莉酸和茉莉酮酸甲酯的生物过程,以及由此产生的新型茉莉酸异构体及其感官应用。 该方法得到根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基)或根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基 )。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(αD20)是新颖的。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(αD20)也是新颖的。 本发明的方法包括在营养培养基中培养一种或多种特异性棉花Diplodia gossypina菌株的好氧条件,然后通过(1)分离茉莉酸产物或(2)茉莉酸酯化形成茉莉酸甲酯,随后 通过分离这种方法生产的茉莉酸甲酯和新产品。

    Process for preparing compositions containing unsaturated lactones,
products produced thereby and organoleptic uses of said products
    18.
    发明授权
    Process for preparing compositions containing unsaturated lactones, products produced thereby and organoleptic uses of said products 失效
    制备含有不饱和内酯的组合物,由此生产的产品和所述产品的感官用途的方法

    公开(公告)号:US4946782A

    公开(公告)日:1990-08-07

    申请号:US228512

    申请日:1988-08-05

    摘要: Described is a process for the preparation of compositions of matter containing unsaturated lactones defined according to the generic structure: ##STR1## wherein R represents C.sub.6 alkyl or alkenyl; and X represents C.sub.2, C.sub.4 or C.sub.6 alkylene or alkenylene; with the provisos that R is C.sub.6 alkyl when X is alkenylene and R is C.sub.6 alkenyl when X is alkylene by means of the sequential steps of (i) fermentation of castor oil or ricinoleic acid using a microorganism selected from the group consisting of:Candida petrophilum, ATCC 20226;Candida oleophila, ATCC 20177;Candida sp., ATCC 20504; andCandida sake, ATCC 28137whereby gamma hydroxydecanoic acid and a mixture of other acids defined according to the generic structure: ##STR2## is formed wherein Y represents an oxo-saturated, oxo-unsaturated or di-unsaturated C.sub.9, C.sub.11 or C.sub.13 moiety according to the reaction: ##STR3## (ii) lactonization of the resulting gamma hydroxydecanoic acid by means of simultaneous acidification and heating according to the reaction: ##STR4## and (iii) lactonization (via distillation) of one or more of the resulting acids defined according to the structure: ##STR5## to form one or more lactones defined according to the generic structure: ##STR6## according to the reaction: ##STR7## wherein the sum of the number of carbon atoms in the X moiety and in the R moiety is equal to the number of carbon atoms in the Y moiety minus 1.Also described are the products produced according to such process as well as their organoleptic utilities for augmenting or enhancing the aroma or taste of consumable materials selected from the group consisting of perfume compositions, colognes, perfumed articles, foodstuffs, chewing gums, medicinal products, toothpastes, chewing tobaccos and smoking tobaccos.

    摘要翻译: 描述了根据通用结构定义的含有不饱和内酯的物质组合物的方法:其中R表示C6烷基或烯基; X表示C2,C4或C6亚烷基或亚烯基; 条件是当X是亚烯基时R是C6烷基,当X是亚烷基时,R是C6链烯基,通过以下顺序的步骤:(i)使用选自以下的微生物来蓖麻油或蓖麻油酸发酵:念珠菌 ,ATCC 20226; 嗜油假丝酵母,ATCC 20177; 念珠菌属,ATCC 20504; 和念珠菌,ATCC 28137,由此形成根据通用结构定义的γ-羟基癸酸和其它酸的混合物:其中Y表示氧代饱和的,不饱和的或不饱和的C 9,C 11或C 13部分,根据 (ii)通过根据以下反应的同时酸化和加热来对所得的γ-羟基癸酸进行内酯化:(ⅲ)内酯化(经蒸馏) 根据以下结构定义的一种或多种所得酸:以形成根据通用结构定义的一种或多种内酯:根据该反应:其中,碳原子数 X部分和R部分等于Y部分中的碳原子数减1。还描述了根据这种方法产生的产物以及它们的感官效用,用于增强或增强co的香气或味道 选自香水组合物,古龙水,香料制品,食品,口香糖,药用产品,牙膏,咀嚼烟草和吸烟烟草的可选材料。