公开(公告)号：US09349545B2

公开(公告)日：2016-05-24

申请号：US14414174

申请日：2013-07-22

Applicant: MYCARTIS NV

Inventor： Raphael Tornay ,  Nicolas Demierre ,  Stephan Gamper ,  Philippe Renaud

IPC: H01G13/06 ,  B01L3/00 ,  B81C99/00 ,  G01N33/543

CPC classification number: H01G13/06 ,  B01J2219/005 ,  B01J2219/00502 ,  B01J2219/00536 ,  B01J2219/00556 ,  B01J2219/00637 ,  B01L3/502707 ,  B01L3/502761 ,  B01L3/508 ,  B01L3/54 ,  B01L3/545 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0803 ,  B01L2300/0819 ,  B01L2300/0851 ,  B01L2300/0893 ,  B81B2201/058 ,  B81B2201/06 ,  B81C99/008 ,  G01N33/54313

Abstract: The present invention relates to a method for producing microcarriers comprising the following steps: (a) providing a wafer having a sandwich structure comprising a bottom layer, a top layer and an insulating layer located between said bottom and top layers, (b) etching away the top layer to delineate lateral walls of bodies of the microcarriers, (c) depositing a first active layer at least on a top surface of the bodies, (d) applying a continuous polymer layer over the first active layer, (e) etching away the bottom layer and the insulating layer, (f) removing the polymer layer to release the microcarriers.

Abstract translation: 本发明涉及一种生产微载体的方法，包括以下步骤：（a）提供具有夹层结构的晶片，该夹层结构包括位于所述底层和顶层之间的底层，顶层和绝缘层，（b）蚀刻掉 描绘微载体的主体的侧壁的顶层，（c）至少在主体的顶表面上沉积第一有源层，（d）在第一有源层上施加连续聚合物层，（e）蚀刻掉 底层和绝缘层，（f）去除聚合物层以释放微载体。

公开(公告)号：US20150190807A1

公开(公告)日：2015-07-09

申请号：US14413518

申请日：2013-07-02

Applicant: MYCARTIS NV

Inventor： Laurent Coulot ,  Nicolas Demierre ,  Raphael Tornay

IPC: B01L3/00

CPC classification number: B01L3/502761 ,  B01L3/502715 ,  B01L3/50273 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0647 ,  B01L2300/0858 ,  Y10T436/2575

Abstract: The present invention relates to a method for injecting microparticles into a microfluidic channel by means of injecting means, said microfluidic channel opening out on a sidewall of an inlet well, the method comprising the steps of: a) positioning the injecting means tip above said sidewall and at a predetermined distance (d) therefrom, and b) injecting the microparticles into said inlet well so that they come into contact with said sidewall during injection, the sidewall being tilted so that at least a portion of the microparticles included in the injected liquid sample slides on the sidewall and enters the microfluidic channel.

Abstract translation: 本发明涉及一种通过注入装置将微粒注入微流体通道的方法，所述微流体通道在入口井的侧壁上开口，该方法包括以下步骤：a）将注射装置尖端定位在所述侧壁上方 并且在其预定距离（d）处，并且b）将微粒注入所述入口孔，使得它们在注射期间与所述侧壁接触，所述侧壁倾斜，使得包含在注射液体中的至少一部分微粒 样品在侧壁上滑动并进入微流体通道。