公开(公告)号：US20160046917A1

公开(公告)日：2016-02-18

申请号：US14773715

申请日：2014-03-07

Applicant: NOVOZYMES A/S ,  NOVOZYMES, INC.

Inventor： Kim Borch ,  Kenneth Jensen ,  Kristian Krogh ,  Brett McBrayer ,  Peter Westh ,  Jeppe Kari ,  Johan Olsen ,  Trine Sorensen ,  Michael Windahl ,  Hui Xu

IPC: C12N9/42 ,  C12P19/02 ,  C12N15/82 ,  C12P19/14

CPC classification number: C12N9/2437 ,  C12N15/8246 ,  C12N15/8257 ,  C12P19/02 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01091

Abstract: The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及纤维二糖水解酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US09938552B2

公开(公告)日：2018-04-10

申请号：US15026486

申请日：2014-10-31

Applicant: Novozymes A/S

Inventor： Hui Xu ,  Jesper Frickman ,  Jiyin Liu ,  Katja Salomon Johansen ,  Hong Zhi Huang

IPC: C12N9/42 ,  C12P19/14 ,  C12P19/02 ,  C12P7/10

CPC classification number: C12P19/14 ,  C12P7/10 ,  C12P19/02 ,  C12P2203/00 ,  Y02E50/16

Abstract: The invention relates to methods of saccharifying a cellulosic material comprising subjecting the cellulosic material to a catalase and a cellulolytic enzyme composition comprising a GH61 polypeptide in the presence of dissolved oxygen at a concentration of greater than 10% of the saturation level. The invention also related to methods of producing desired fermentation products, such as ethanol, using a method including a saccharification step of the invention.

公开(公告)号：US20160298154A1

公开(公告)日：2016-10-13

申请号：US14916119

申请日：2014-09-04

Applicant: Novozymes A/S

Inventor： Jiyin Liu ,  Hui Xu ,  Feng Xu ,  Ye Chen ,  Terry Green

IPC: C12P19/14 ,  C12P19/02

CPC classification number: C12P19/14 ,  C12N9/0061 ,  C12N9/0065 ,  C12N9/0071 ,  C12P19/02 ,  C12P2201/00 ,  C12P2203/00 ,  C12Y110/03002 ,  C12Y111/01006 ,  C12Y302/01004 ,  C13K1/02 ,  Y02E50/17

Abstract: The present invention relates to methods for increasing hydrolysis of a cellulosic material, comprising: hydrolyzing the cellulosic material with an enzyme composition in the presence of a combination of an AA9 polypeptide and one or more oxidoreductases selected from the group consisting of a catalase, a laccase, and a peroxidase.

Abstract translation: 本发明涉及增加纤维素材料水解的方法，其包括：在AA9多肽和一种或多种选自过氧化氢酶，漆酶的一种或多种氧化还原酶的组合存在下，用酶组合物水解纤维素材料 ，和过氧化物酶。

公开(公告)号：US20150315622A1

公开(公告)日：2015-11-05

申请号：US14762133

申请日：2014-02-21

Applicant: NOVOZYMES A/S

Inventor： Jesper Frickmann ,  Armindo Ribiero Gaspar ,  Mark Stevens ,  Hui Xu ,  Katja Salomon Johansen

IPC: C12P19/14 ,  C12P7/14 ,  C12P19/02

CPC classification number: C12P19/14 ,  C12P3/00 ,  C12P5/023 ,  C12P5/026 ,  C12P7/02 ,  C12P7/10 ,  C12P7/14 ,  C12P7/40 ,  C12P13/04 ,  C12P19/02 ,  C12Y302/01 ,  Y02E50/16 ,  Y02E50/17

Abstract: The invention relates to methods of saccharifying a cellulosic material comprising subjecting the cellulosic material to a cellulolytic enzyme composition and a GH61 polypeptide, and optionally a catalase in the presence of dissolved oxygen at a concentration in the range of 0.5 to 10% of the saturation level. The invention also related to methods of producing desired fermentation products, such as ethanol, using a method including a saccharification step of the invention.

Abstract translation: 本发明涉及糖化纤维素材料的方法，包括将纤维素材料经受纤维素分解酶组合物和GH61多肽，以及任选地在溶解氧存在下的浓度为饱和度的0.5至10％范围内的过氧化氢酶 。 本发明还涉及使用包括本发明的糖化步骤的方法生产所需发酵产物如乙醇的方法。

公开(公告)号：US20140262093A1

公开(公告)日：2014-09-18

申请号：US14345133

申请日：2012-09-10

Applicant: Novozymes A/S

Inventor： Pierre Cassland ,  Hui Xu ,  Henrik Lund

IPC: D21H17/22

CPC classification number: D21H17/22 ,  D21C5/005 ,  D21H17/005 ,  D21H21/18 ,  D21H21/20 ,  D21H27/10

Abstract: The use of GH61 polypeptides in the treatment of pulp, for improving tear strength and/or tensile strength of the corresponding paper materials, such as paper, linerboard, corrugated paperboard, tissue, towels, corrugated containers and boxes.

Abstract translation: 在处理纸浆中使用GH61多肽来改善相应纸材的撕裂强度和/或拉伸强度，例如纸张，纸板，瓦楞纸板，纸巾，毛巾，波纹状容器和盒子。

公开(公告)号：US20150140612A1

公开(公告)日：2015-05-21

申请号：US14413829

申请日：2013-07-18

Applicant: Novozymes A/S

Inventor： Ye Chen ,  Jiyin Liu ,  Terry Green ,  Mark V. Stevens ,  Hui Xu

IPC: C12P19/02 ,  C12P19/14

CPC classification number: C12P19/02 ,  C12N9/0065 ,  C12N9/2437 ,  C12P7/10 ,  C12P19/14 ,  C12P2203/00 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention relates to methods for increasing hydrolysis of a pretreated cellulosic material, comprising subjecting the pretreated cellulosic material to a cellulolytic enzyme composition; a polypeptide having cellulolytic enhancing activity; a Peroxidase; and a nonionic surfactant and/or cationic surfactant, at conditions suitable for hydrolyzing the pretreated lignocellulosic material. The invention also relates to processes for producing a fermentation product comprising a hydrolysis step of the invention and a composition suitable for use in a method of the invention.

Abstract translation: 本发明涉及增加预处理纤维素材料水解的方法，包括将经预处理的纤维素材料经受纤维素分解酶组合物; 具有纤维素分解增强活性的多肽; 过氧化物酶; 和非离子表面活性剂和/或阳离子表面活性剂，在适于水解预处理的木质纤维素材料的条件下。 本发明还涉及用于生产包含本发明的水解步骤和适用于本发明方法的组合物的发酵产物的方法。

公开(公告)号：US10407704B2

公开(公告)日：2019-09-10

申请号：US14762133

申请日：2014-02-21

Applicant: Novozymes A/S

Inventor： Jesper Frickmann ,  Armindo Ribiero Gaspar ,  Mark Stevens ,  Hui Xu ,  Katja Salomon Johansen

IPC: C12P7/02 ,  C12P7/06 ,  C12P1/00 ,  C12P19/14 ,  C12P7/14 ,  C12P19/02 ,  C12P7/10 ,  C12P3/00 ,  C12P5/02 ,  C12P7/40 ,  C12P13/04

Abstract: The invention relates to methods of saccharifying a cellulosic material comprising subjecting the cellulosic material to a cellulolytic enzyme composition and a GH61 polypeptide, and optionally a catalase in the presence of dissolved oxygen at a concentration in the range of 0.5 to 10% of the saturation level. The invention also related to methods of producing desired fermentation products, such as ethanol, using a method including a saccharification step of the invention.

公开(公告)号：US20190055531A1

公开(公告)日：2019-02-21

申请号：US16178286

申请日：2018-11-01

Applicant: Novozymes A/S

Inventor： Kim Borch ,  Kenneth Jensen ,  Kristian Krogh ,  Brett McBrayer ,  Peter Westh ,  Jeppe Kari ,  Johan Olsen ,  Trine Sorensen ,  Michael Windhal ,  Hui Xu

IPC: C12N9/42 ,  C12N15/82 ,  C12P19/14 ,  C12P19/02

CPC classification number: C12N9/2437 ,  C12N15/8246 ,  C12N15/8257 ,  C12P19/02 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01091

Abstract: The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20230012672A1

公开(公告)日：2023-01-19

申请号：US17642925

申请日：2020-09-16

Applicant: Novozymes A/S

Inventor： Hong Zhi Huang ,  Jiyin Liu ,  Hui Xu ,  Elena Vlasenko ,  Brett McBrayer ,  Ye Liu ,  Lan Tang ,  James Ron Huffman ,  Nikolaj Spodsberg

IPC: C12N9/24 ,  C12N1/18 ,  C12N15/81 ,  C12P7/06

Abstract: The present invention relates to isolated polypeptides having beta-glucanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules. The present invention further relates to processes for producing fermentation products from starch-containing or cellulosic-containing material, as well as an enzyme blend or composition, or a recombinant host cell or fermenting organism suitable for use in processes of the invention.

公开(公告)号：US10793887B2

公开(公告)日：2020-10-06

申请号：US15513896

申请日：2015-08-21

Applicant: Novozymes A/S

Inventor： Hui Xu ,  Jesper Frickmann ,  Katja Salomon Johansen

IPC: C12P3/00 ,  C12P5/02 ,  C12P7/02 ,  C12P7/26 ,  C12P7/40 ,  C12P13/04 ,  C12P19/02 ,  C12P19/14

Abstract: The invention relates to methods of saccharifying a cellulosic material comprising subjecting the cellulosic material to a laccase and a cellulolytic enzyme composition comprising a GH61 polypeptide in the presence of dissolved oxygen at a concentration in the range of 0.5-90% of the saturation level. The invention also related to methods of producing desired fermentation products, such as ethanol, using a method including a saccharification step of the invention.