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公开(公告)号：US20170169573A1
公开(公告)日：2017-06-15
申请号：US14966694
申请日：2015-12-11
Applicant: Novartis AG
Inventor： Hugang Ren , Lingfeng Yu
CPC classification number: G06T7/181 , G06T7/0083 , G06T7/0093 , G06T7/13 , G06T7/162 , G06T7/408 , G06T7/90 , G06T2207/10101 , G06T2207/10132 , G06T2207/20016 , G06T2207/20136 , G06T2207/30041
Abstract: A method of processing an ophthalmic image includes: taking an image of an ophthalmic region involving an ophthalmic layer by an imaging system; constructing an image graph, comprising nodes connected by links and detected image data by an image processor; and performing a heuristic graph-search for a path on the image graph that corresponds to an image of the ophthalmic layer by assigning at least one of link-costs to links of the image graph and node-costs to nodes of the image graph; assigning heuristic-costs to at least one of the nodes and the links; creating extended paths by extending a selected path with extension links; determining path-costs of the extended paths by combining heuristic costs and at least one of link-costs and node-costs assigned to the extension-links; and selecting the extended path with the smallest path-cost.
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公开(公告)号：US09560959B1
公开(公告)日：2017-02-07
申请号：US14858701
申请日：2015-09-18
Applicant: NOVARTIS AG
Inventor： Mark Hopkins , Robert Sanchez , Ryan Takakawa , Lingfeng Yu , Hugang Ren
CPC classification number: A61B3/0025 , A61B3/0033 , A61B3/0058 , A61B3/102 , A61B3/13 , A61B90/20 , A61F9/00821 , A61F2009/00863
Abstract: Control of scanning images during ophthalmic surgery may be performed with a scanning controller that interfaces to an optical scanner used with a surgical microscope. A scan control device may receive user input, including hands-free user input, for controlling an overlay image of scanning data that is overlaid on optical image data viewed using the surgical microscope. A selected location for optical scanning may also be displayed and controlled using the scanning controller.
Abstract translation: 可以用与外科显微镜一起使用的光学扫描器相连接的扫描控制器来执行在眼科手术期间扫描图像的控制。 扫描控制装置可以接收用户输入，包括免提用户输入，用于控制覆盖在使用手术显微镜观察的光学图像数据上的扫描数据的覆盖图像。 也可以使用扫描控制器显示和控制用于光学扫描的选定位置。
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13.发明申请公开(公告)号：US20150366450A1
公开(公告)日：2015-12-24
申请号：US14309618
申请日：2014-06-19
Applicant: Novartis AG
Inventor： Hugang Ren , Lingfeng Yu
CPC classification number: A61B3/102 , A61B3/0025 , A61B3/12 , G06T7/0012 , G06T2207/10101 , G06T2207/30041
Abstract: A method of automatically detecting a retinal feature using an ophthalmic imaging system can include: acquiring an optical coherence tomography (OCT) image of a retina; segmenting the OCT image; generating a metric based on the segmented OCT image; detecting the retinal feature based on the metric; and providing an indication of the detected retinal feature to a user. An ophthalmic imaging system can include: an OCT system configured to acquire an image of a retina; a computing device coupled to the OCT system and configured to segment the image, generate a metric based on the segmented image, and detect a retinal feature based on the metric; and an audio/visual/tactile device in communication with the computing device and configured to provide at least one of an audio, visual, and tactile indication of the detected retinal feature to a user.
Abstract translation: 使用眼科成像系统自动检测视网膜特征的方法可以包括：获取视网膜的光学相干断层摄影（OCT）图像; 分割OCT图像; 基于分割的OCT图像生成度量; 基于度量检测视网膜特征; 以及向用户提供检测到的视网膜特征的指示。 眼科成像系统可以包括：OCT系统，被配置为获取视网膜的图像; 耦合到所述OCT系统并被配置为分割所述图像的计算设备，基于所述分割的图像生成度量，并且基于所述度量来检测视网膜特征; 以及与所述计算设备通信并被配置为向用户提供检测到的视网膜特征的音频，视觉和触觉指示中的至少一个的音频/视觉/触觉设备。
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公开(公告)号：US10408601B2
公开(公告)日：2019-09-10
申请号：US15808070
申请日：2017-11-09
Applicant: Novartis AG
Inventor： Hugang Ren , Lingfeng Yu
Abstract: The present disclosure provides a visualization system for performing optimized optical coherence tomography (OCT) by determining the absolute distance between the OCT source and a sample. The present disclosure also provides a method for optimizing OCT, which includes determining an absolute distance between the OCT source and a sample using data relating to the focal length or position of an autofocus imager lens.
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公开(公告)号：US10285584B2
公开(公告)日：2019-05-14
申请号：US15695608
申请日：2017-09-05
Applicant: NOVARTIS AG
Inventor： Steven T. Charles , Lingfeng Yu , Hugang Ren
IPC: G06K9/00 , A61B3/10 , G06T7/11 , A61B3/00 , A61B3/13 , G06T7/00 , G06T11/60 , A61B3/12 , G06T5/50 , G06T11/00
Abstract: En face or 3D volumetric OCT imaging during ophthalmic surgery may be performed with an OCT scanning controller that interfaces to an OCT scanner used with a surgical microscope. The OCT scanner may generate en face images before and after surgical operations, such as retinal membrane peeling, are performed. Using digital subtraction on the en face images, an overlay image indicative of the changes from the surgical operations to the eye may be generated and overlaid onto an optical image displayed to a user of the surgical microscope.
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Patent Agency Ranking
公开(公告)号：US09844319B2
公开(公告)日：2017-12-19
申请号：US14837341
申请日：2015-08-27
Applicant: NOVARTIS AG
Inventor： Michael J. Papac , Hugang Ren , Lingfeng Yu
IPC: A61B3/14 , A61B3/00 , A61B3/10 , A61B90/00 , A61B3/12 , A61B3/13 , A61F9/007 , G02B27/01 , A61F9/008
CPC classification number: A61B3/102 , A61B3/0025 , A61B3/0058 , A61B3/12 , A61B3/1225 , A61B3/13 , A61B3/145 , A61B90/06 , A61B90/37 , A61F9/00736 , A61F2009/00851 , A61F2009/00863 , G02B27/0101 , G02B2027/0141
Abstract: An epiretinal membrane (ERM) visualization system includes an OCT system operable to generate an OCT image of a region of a patient's eye, the region of the patient's eye including an ERM. The ERM visualization system further includes an image processing unit operable to process the OCT image to identify the ERM by differentiating the ERM from other structures within the region of the patient's eye and generate an ERM map depicting one or more characteristics (including at least a location of a portion of the ERM within the region of the patient's eye) of the identified ERM. The ERM visualization system further includes a display operable to display the ERM map.
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公开(公告)号：US09826900B2
公开(公告)日：2017-11-28
申请号：US14827473
申请日：2015-08-17
Applicant: NOVARTIS AG
Inventor： Tammo Heeren , Hugang Ren , Vadim Shofman , Lingfeng Yu
CPC classification number: A61B3/132 , A61B3/0025 , A61B3/10 , A61B3/102 , A61B3/12
Abstract: An ophthalmic surgical microscope includes a beam coupler positioned along an optical path of the surgical microscope between a first eyepiece and magnifying/focusing optics, the beam coupler operable to direct the OCT imaging beam along a first portion of the optical path of the surgical microscope between the beam coupler and a patient's eye (an OCT image being generated based on a reflected portion of the OCT imaging beam). The surgical microscope additionally includes a real-time data projection unit operable to project the OCT image generated by the OCT system and a beam splitter positioned along the optical path of the surgical microscope between a second eyepiece and the magnifying/focusing optics. The beam splitter is operable to direct the projected OCT image along a second portion of the optical path of the surgical microscope between the beam splitter and the second eyepiece such that the projected OCT image is viewable through the second eyepiece.
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公开(公告)号：US20170156588A1
公开(公告)日：2017-06-08
申请号：US14957306
申请日：2015-12-02
Applicant: Novartis AG
Inventor： Hugang Ren , Lingfeng Yu
CPC classification number: A61B3/102 , A61B3/0025 , A61B3/0058 , A61B3/13 , A61B3/14 , A61B3/18 , A61B34/20 , A61B2034/2055 , G02B21/0012
Abstract: An ophthalmic visualization system can include a computing device in communication with an OCT system configured to scan a surgical field to generate an OCT image. The computing device can be configured to determine locations within the surgical field corresponding to locations within the OCT image. The ophthalmic visualization system can also include an indicator mechanism in communication with the computing device and a surgical microscope configured to image the surgical field. The indicator mechanism can be configured to cause a location indicator to be positioned within a field of view of the surgical microscope. The location indicator can graphically represent the locations within the surgical field corresponding to the locations within the OCT image.
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19.发明申请SYSTEMS, APPARATUSES, AND METHODS FOR THE OPTIMIZATION OF LASER PHOTOCOAGULATION 审中-公开用于优化激光照相机的系统，设备和方法公开(公告)号：US20160278983A1
公开(公告)日：2016-09-29
申请号：US15050903
申请日：2016-02-23
Applicant: NOVARTIS AG
Inventor： Michael John Claus , Robert Sanchez , Tammo Heeren , Argelio Michael Olivera , Michael Papac , Lingfeng Yu , Hugang Ren
IPC: A61F9/008
CPC classification number: A61F9/00821 , A61B34/10 , A61F9/008 , A61F2009/00846 , A61F2009/00851 , A61F2009/00863 , A61F2009/00878 , A61F2009/00897
Abstract: Apparatuses, systems, and methods for treating tissue abnormalities are disclosed. The tissue may be visualized for determining a presence of one or more abnormalities contained therein. Imaging data obtained by visualization may be used to determine the presence of one or more abnormalities. Each of the detected abnormalities may be identified and a treatment plan developed for treating the abnormalities. Treatment may be delivered to the abnormalities according to the treatment plan.
Abstract translation: 公开了用于治疗组织异常的装置，系统和方法。 可以将组织可视化以确定其中包含的一种或多种异常的存在。 通过可视化获得的成像数据可用于确定一个或多个异常的存在。 可以识别每个检测到的异常，并且开发用于治疗异常的治疗计划。 根据治疗计划，治疗可能会发生异常。
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公开(公告)号：US09392936B1
公开(公告)日：2016-07-19
申请号：US14623317
申请日：2015-02-16
Applicant: NOVARTIS AG
Inventor： Lingfeng Yu , Hugang Ren
CPC classification number: A61B3/0025 , A61B3/0058 , A61B3/102 , A61B3/12 , A61B3/14 , G06T5/50 , G06T2207/10101 , G06T2207/30041
Abstract: A system and method for using optical coherence tomography (OCT) to image both the vitreous and the retina in the eye. The image of both tissues may be created sequentially, simultaneously, or near-simultaneously from at least one OCT image.
Abstract translation: 一种使用光学相干断层扫描（OCT）来对眼睛中的玻璃体和视网膜进行成像的系统和方法。 可以从至少一个OCT图像顺序地，同时地或几乎同时地创建两个组织的图像。
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