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公开(公告)号：US20050036529A1
公开(公告)日：2005-02-17
申请号：US10641398
申请日：2003-08-14
申请人： Robert Monson , Trevor McCollough , Jianhua Yan
发明人： Robert Monson , Trevor McCollough , Jianhua Yan
CPC分类号： H01S5/02256 , H01L2924/0002 , H01S5/0021 , H01S5/183 , H01S5/423 , H01L2924/00
摘要： A VCSEL settling fixture provides for a plurality of VCSEL chip packages to be selectively tested within a burn-in or environmental chamber having a remote pendant controller. The settling fixture includes a mounting frame including a plurality of recesses and throughbores for positioning and aligning the VCSEL's on the mounting frame. The mounting frame further includes a plurality of terminal blocks in proximity to the recesses for interconnecting the mounting frame with the controller. An activation system including a plurality of electrical contacts electrically connects the individual VCSEL chip packages with the terminal blocks so that the controller can selectively trigger a laser output from the VCSEL chip package.
摘要翻译： VCSEL沉降夹具提供多个VCSEL芯片封装，以在具有远程侧挂控制器的老化或环境室内进行选择性测试。 沉降固定装置包括安装框架，该安装框架包括用于在安装框架上定位和对准VCSEL的多个凹槽和通孔。 安装框架还包括靠近凹部的多个端子块，用于将安装框架与控制器互连。 包括多个电触点的激活系统将各个VCSEL芯片封装与端子块电连接，使得控制器能够选择性地触发来自VCSEL芯片封装的激光输出。
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公开(公告)号：US6079632A
公开(公告)日：2000-06-27
申请号：US756406
申请日：1996-11-26
申请人： Jianhua Yan
发明人： Jianhua Yan
CPC分类号： B05B7/2486 , A01M7/0092 , B05B12/1418 , B05B7/32 , F16L37/24
摘要： A comprehesive product dispensing system including a product/carrier dispensing system. The product carrier dispensing system comprising a carrier dispensing system and a product dispensing system. The product dispensing system including a product dispensing device and a product dispensing control system. The product dispensing control system includes a flowmeter and a controller. The controller regulates the injection rate of product injected into the carrier and the flowmeter provides feedback to the controller for regulating the injection rate of product. Product is dispensed from product containers which may be filled via a closed transfer delivery system for safe product handling and transfer.
摘要翻译： 一种包括产品/载体分配系统的混合产品分配系统。 产品载体分配系统包括载体分配系统和产品分配系统。 产品分配系统包括产品分配装置和产品分配控制系统。 产品分配控制系统包括流量计和控制器。 控制器调节注入到载体中的产品的注入速率，流量计向控制器提供调节产品注射速率的反馈。 产品从产品容器中分配，可以通过封闭的转运系统填充，以便安全的产品处理和转移。
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13.发明授权Methods for diagnosing scapuloperoneal spinal muscular atrophy or Charcot-Marie-Tooth disease type 2C by detecting mutations in TRPV4 有权通过检测TRPV4突变来诊断肩峰肩胛骨脊髓性肌萎缩或2C型Charcot-Marie-Tooth病的方法公开(公告)号：US08394589B2
公开(公告)日：2013-03-12
申请号：US12974209
申请日：2010-12-21
申请人： Teepu Siddique , Han-Xiang Deng , Jianhua Yan
发明人： Teepu Siddique , Han-Xiang Deng , Jianhua Yan
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04 , C07K14/435 , G01N33/53
CPC分类号： C12Q1/6883 , C12Q2600/156
摘要： The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4 (TRPV4). In particular, mutations are detected in TRPV4 to detect diseases such as scapuloperoneal spinal muscular atrophy (SPSMA) and hereditary motor and sensory neuropathy type IIC (HMSN IIC) or Charcot-Marie-Tooth disease type 2C (CMT2C).
摘要翻译： 本发明提供了用于检测瞬时受体潜在阳离子通道，子族V，成员4（TRPV4）中的突变的方法，试剂盒和组合物。 特别地，在TRPV4中检测到突变以检测诸如肩胛骨皮质脊髓性肌萎缩（SPSMA）和遗传性运动和感觉神经病IIC型（HMSN IIC）或2C型（Charlotta Marie-Tooth disease）的CMT2C。
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公开(公告)号：US20050288379A1
公开(公告)日：2005-12-29
申请号：US11156211
申请日：2005-06-17
申请人： Xiaoqiang Yan , Yumin Cui , Jianhua Yan , Weihan Zhang , Jifeng Duan , Jian Zuo
发明人： Xiaoqiang Yan , Yumin Cui , Jianhua Yan , Weihan Zhang , Jifeng Duan , Jian Zuo
IPC分类号： A61K31/12
CPC分类号： A61K31/12
摘要： This invention relates to a method of treating certain cancers by administering an effective amount of a compound of the following formula: wherein R1, R2, R3, and R4 are defined herein.
摘要翻译： 本发明涉及通过施用有效量的下式化合物来治疗某些癌症的方法：其中R 1，R 2，R 3， / SUB＆gt;和R 4＆gt;在本文中定义。
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15.发明申请Method and apparatus for the integration of a VCSEL flex with a parallel optical transceiver package 失效用于将VCSEL flex与并行光收发器封装集成的方法和装置公开(公告)号：US20050036754A1
公开(公告)日：2005-02-17
申请号：US10640583
申请日：2003-08-13
申请人： Robert Monson , Richard Cellini , Jianhua Yan
发明人： Robert Monson , Richard Cellini , Jianhua Yan
CPC分类号： G02B6/4249 , G02B6/4228 , G02B6/4239 , G02B6/4246 , G02B6/4292
摘要： A method of integrating an optoelectronic device, for example a vertical cavity surface emitting laser, onto the electronic substrate of a parallel optical transceiver package by positioning and maintaining the exact relative alignment of the optoelectronic device relative to the electronic substrate for application of adhesive and curing. The method includes the utilization of a multi-piece fixture which clamps the elements into position and maintains position throughout the curing process. Alternatively, the fixture can comprise a unitary assembly for clamping the elements into position and maintaining their position throughout the curing process.
摘要翻译： 通过定位和保持光电子器件相对于电子基片的精确相对对准来将光电器件（例如垂直腔表面发射激光器）集成到并行光收发器封装的电子衬底上的方法，用于施加粘合剂和固化 。 该方法包括利用多片固定装置，其将元件夹持在适当的位置并且在整个固化过程中保持位置。 或者，夹具可以包括用于将元件夹持在适当位置并在整个固化过程中保持其位置的整体组件。
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公开(公告)号：US06533657B2
公开(公告)日：2003-03-18
申请号：US09853220
申请日：2001-05-11
IPC分类号： F24F7007
CPC分类号： F24F13/0263 , F24F13/24 , Y10S454/906
摘要： A system including a cabinet for intaking or discharging a gas while minimizing external duct noise and a gas duct for attachment to a housing with the gas duct having a smoothly curved passageway therein with each portion of the passageway having a cross sectional area which is sufficiently large so that the ratio of the inertia forces to viscous forces within the passageway is sufficiently small so that a laminar flow condition is maintained throughout the gas duct.
摘要翻译： 一种包括用于吸入或排出气体同时最小化外部管道噪声的柜体和用于附接到壳体的气体管道的系统，其中气体管道具有平滑弯曲的通道，其中通道的每个部分具有足够大的横截面积 使得通道内的惯性力与粘性力的比例足够小，从而在整个气体管道中保持层流条件。
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公开(公告)号：US06533258B2
公开(公告)日：2003-03-18
申请号：US09779241
申请日：2001-02-08
IPC分类号： F16F136
CPC分类号： F16F15/085 , F16F1/374 , F16F7/00 , F16F9/0409 , F16F15/0232 , F16F2236/12
摘要： A barrel elastomer mount having a first hollow frustum composed of an elastomer and having a first end and a second end with the first end of the first hollow frustum having an interior diameter larger than an external diameter of the second end of the first hollow frustum; and a second hollow frustum composed of an elastomer having a first end and a second end with the first end of the second hollow frustum having an interior diameter larger than an external diameter of the second end of the second hollow frustum. The first hollow frustum is securely attached to the second hollow frustum at the first end of the first hollow frustum and at the first end of the second hollow frustum creating an enclosed cavity whereby the walls of the elastomer mount provide tension and shear resistance to shock and vibrational forces as well as to compressive static forces.
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公开(公告)号：US20110151445A1
公开(公告)日：2011-06-23
申请号：US12974209
申请日：2010-12-21
申请人： Teepu Siddique , Han-Xiang Deng , Jianhua Yan
发明人： Teepu Siddique , Han-Xiang Deng , Jianhua Yan
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/156
摘要： The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4 (TRPV4). In particular, mutations are detected in TRPV4 to detect diseases such as scapuloperoneal spinal muscular atrophy (SPSMA) and hereditary motor and sensory neuropathy type IIC (HMSN IIC) or Charcot-Marie-Tooth disease type 2C (CMT2C).
摘要翻译： 本发明提供了用于检测瞬时受体潜在阳离子通道，子族V，成员4（TRPV4）中的突变的方法，试剂盒和组合物。 特别地，在TRPV4中检测到突变以检测诸如肩胛骨皮质脊髓性肌萎缩（SPSMA）和遗传性运动和感觉神经病IIC型（HMSN IIC）或2C型（Charlotta Marie-Tooth disease）的CMT2C。
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公开(公告)号：US20080302710A1
公开(公告)日：2008-12-11
申请号：US12134571
申请日：2008-06-06
申请人： Zhanjun Zhang , Dongwen Shi , Kexin Zhang , Chunying Zhao , Xiangyang Song , Degang Huang , Jianyu Zhang , Wenhong Wu , Ying Lin , Wei Zhang , Junfeng Sun , Yonghong Wang , Hongjie Wang , Junya Wang , Jianhua Yan , Xiang Dong , Wenjie Mao , Ling Shen , Feng Shen , Xianwu Liu
发明人： Zhanjun Zhang , Dongwen Shi , Kexin Zhang , Chunying Zhao , Xiangyang Song , Degang Huang , Jianyu Zhang , Wenhong Wu , Ying Lin , Wei Zhang , Junfeng Sun , Yonghong Wang , Hongjie Wang , Junya Wang , Jianhua Yan , Xiang Dong , Wenjie Mao , Ling Shen , Feng Shen , Xianwu Liu
IPC分类号： C02F1/76
摘要： The invention discloses a pulsating chlorination machine for purification of city water. The machine includes a body, two ends of which are respectively a water inlet and outlet end between which a converging pipe, a throat pipe and a diverging pipe are connected in turn; and a liquefied chlorine input port located below a middle part of the throat pipe and connecting with the throat pipe via a cone-shaped valve seat. A normally closed cone-shaped valve rod is mounted over the cone-shaped valve seat and inserted into the throat pipe through a vertical circular hole on a top of the body, and moves up and down under the control of a pulsating electromagnetic executive mechanism to open/close the liquefied chlorine input port. Through the liquefied chlorine input port the liquefied chlorine flows into the throat pipe and out from the diverging pipe and then into a clear-water reservoir.
摘要翻译： 本发明公开了一种用于净化城市用水的脉动氯化机。 机器包括主体，其两端分别为进水口和出口端，依次连接汇流管，喉管和发散管; 以及液化氯输入口，位于喉管的中部下方并通过锥形阀座与喉管连接。 常闭锥形阀杆安装在锥形阀座上，并通过身体顶部的垂直圆孔插入喉管，并在脉动电磁执行机构的控制下上下移动 打开/关闭液化氯输入口。 通过液化氯输入口，液化氯流入喉管，从分流管中流出，然后进入清水储存器。
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公开(公告)号：US20060178859A1
公开(公告)日：2006-08-10
申请号：US11051829
申请日：2005-02-04
申请人： Robert Monson , Julia Neuman , Jianhua Yan
发明人： Robert Monson , Julia Neuman , Jianhua Yan
IPC分类号： G06G7/48
CPC分类号： F16F15/00 , Y10T428/233
摘要： The present invention provides a method for designing a frequency-shifting isolator system that includes selecting, an impact absorption envelope; a geometry for the isolator mount system; and an elastomeric dampening material formed in the selected geometry. The isolator mount system is preferably configured to shift frequencies at predetermined displacements upon impact, at or before the system attains resonance.
摘要翻译： 本发明提供了一种用于设计变频隔离器系统的方法，该系统包括选择冲击吸收包络; 隔离器安装系统的几何形状; 以及以所选择的几何形状形成的弹性体阻尼材料。 隔离器安装系统优选地被配置为在系统达到共振之前或之前在冲击时以预定位移移动频率。
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