公开(公告)号：US20170227440A1

公开(公告)日：2017-08-10

申请号：US15502630

申请日：2015-08-07

Applicant: Sphere Fluidics Limited

Inventor： Clive Adrian Smith ,  Xin Li ,  Frank F. Craig

IPC: G01N15/10 ,  B01L3/00

Abstract: We describe a method comprising: providing a droplet comprising a plurality of constituents, splitting said droplet into a first droplet and a second droplet, wherein said first droplet comprises a first fraction of said plurality of constituents and said second droplet comprises a second fraction of said plurality of constituents, analysing said constituents of said first fraction of said plurality of constituents in said first droplet, and sorting said second droplet dependent on an outcome of said analysis.

公开(公告)号：US09513207B2

公开(公告)日：2016-12-06

申请号：US14907936

申请日：2014-07-30

Applicant: Sphere Fluidics Limited

Inventor： Clive A. Smith ,  Xin Li ,  Karine Enesa ,  Xin Liu ,  Frank F. Craig ,  Graeme Whyte

IPC: A61K9/00 ,  G01N15/14 ,  B01L3/00

CPC classification number: G01N15/1484 ,  B01L3/502784 ,  B01L2200/0652 ,  B01L2200/0673 ,  G01N2015/1481 ,  G01N2015/149

Abstract: The present invention provides an emulsion for sorting droplets in a microfluidic device, the emulsion comprising: a discontinuous aqueous phase; and a continuous oil phase; wherein said aqueous phase comprises at least one analyte, said oil phase comprises a fluorous oil and a refractive index modifying compound comprising at least one aromatic ring, and the refractive index of said aqueous phase and the refractive index of said oil phase are substantially matched.