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公开(公告)号:US10391425B2
公开(公告)日:2019-08-27
申请号:US15318898
申请日:2015-06-16
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Dafeng Chen , James E. Rasmussen , Manish Deshpande
Abstract: A fluidic device and a method for degassing a fluidic device are presented. The fluidic device includes a plurality of fluidic components such as channels, chambers, and integrated valves and pumps, etc. A porous membrane is disposed on a degassing area of the fluidic device for removing gas (such as, for example, bubbles) contained in a liquid. A fluid control device monitors a pressure profile indicating a pressure in the fluidic device over time and applies a pressure differential between two sides of the membrane when activated. The membrane is permeable to gas in the fluidic device and is impermeable to liquids through the pores under the pressure differential. The disclosed method enables degassing large volume of gas at a high flow rate and provides a bubble free filling in a fluidic device which is critical to precision sample metering, mixing, fluid control, reaction, and detection, etc.
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公开(公告)号:US20150352548A1
公开(公告)日:2015-12-10
申请号:US14763588
申请日:2014-01-27
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor: Manish Deshpande , James E. Rasmussen , Dafeng Chen
IPC: B01L3/00
CPC classification number: B01L3/5027 , B01L3/545 , B01L2200/04 , B01L2200/14 , B01L2300/021 , B01L2300/0816 , B01L2400/0481 , B01L2400/0655
Abstract: Microfluidic chips may include one or more microfluidic elements and one or more channels providing fluid communication throughout the microfluidic chip. The microfluidic chips may also include an identifier for identifying a predetermined configuration of the one or more microfluidic elements and the one or more channels from a set of predetermined different configurations of the one or more microfluidic elements and the one or more channels.
Abstract translation: 微流控芯片可以包括一个或多个微流体元件和一个或多个通道,提供贯穿整个微流体芯片的流体连通。 微流体芯片还可以包括用于从一个或多个微流体元件和一个或多个通道的一组预定的不同配置中识别一个或多个微流体元件和一个或多个通道的预定配置的标识符。
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公开(公告)号:US20220018827A1
公开(公告)日:2022-01-20
申请号:US17299816
申请日:2019-12-05
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Jennifer Samproni , Manish Deshpande
Abstract: A blood testing device for detecting hemolysis in a blood sample is described. The blood testing device comprises an housing for containing the blood sample. The housing has a treatment window and an optical zone formed therein. The blood testing device further includes an acoustic transducer positioned to selectively generate acoustic forces directed into the treatment window of the housing and a control unit for selectively actuating and deactuating the acoustic transducer to permit colorimetric analysis of plasma within the blood sample.
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公开(公告)号:US20170197212A1
公开(公告)日:2017-07-13
申请号:US15320629
申请日:2015-06-29
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Manish Deshpande
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L3/5027 , B01L3/502761 , B01L2200/025 , B01L2200/148 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2400/0487 , B01L2400/049
Abstract: A microfluidic test device and analyzer, the test device includes a sample well, at least one reaction well and a calibrator well fluidicly connected to a waste well which in turn is connected to a pump port. When vacuum pressure from the analyzer is applied through the pump port, fluid from the reaction well and the calibrator well are moved to the waste well via transparent flow paths. The analyzer detects objects in the flow paths and calibrates its measurement of the objects in the sample utilizing beads from the calibrator well.
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公开(公告)号:US20170120164A1
公开(公告)日:2017-05-04
申请号:US15318898
申请日:2015-06-16
Applicant: Siemens Healthcare Diagnostics Inc.
Inventor: Dafeng Chen , James E. Rasmussen , Manish Deshpande
IPC: B01D19/00
CPC classification number: B01D19/0031 , B01D19/0063
Abstract: A fluidic device and a method for degassing a fluidic device are presented. The fluidic device includes a plurality of fluidic components such as channels, chambers, and integrated valves and pumps, etc. A porous membrane is disposed on a degassing area of the fluidic device for removing gas (such as, for example, bubbles) contained in a liquid. A fluid control device monitors a pressure profile indicating a pressure in the fluidic device over time and applies a pressure differential between two sides of the membrane when activated. The membrane is permeable to gas in the fluidic device and is impermeable to liquids through the pores under the pressure differential. The disclosed method enables degassing large volume of gas at a high flow rate and provides a bubble free filling in a fluidic device which is critical to precision sample metering, mixing, fluid control, reaction, and detection, etc.
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