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11.发明申请Systems for Comprehensive Fourier Domain Optical Coherence Tomography (FDOCT) and Related Methods 有权综合傅里叶域光学相干断层扫描系统（FDOCT）及相关方法公开(公告)号：US20110102802A1
公开(公告)日：2011-05-05
申请号：US12910184
申请日：2010-10-22
IPC分类号： G01B9/02
CPC分类号： A61B3/102 , A61B3/117 , A61B3/1225 , G01B9/0201 , G01B9/02078 , G01B9/02091
摘要： Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.
摘要翻译： 提供了用于对整个眼睛进行成像的光学相干断层摄影系统，包括包括焦点光学元件的样本臂，其配置为在小于约1.0秒内在至少两个扫描模式之间快速切换。
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12.发明授权Methods, systems and computer program products for analyzing three dimensional data sets obtained from a sample 有权用于分析从样本获得的三维数据集的方法，系统和计算机程序产品公开(公告)号：US08442356B2
公开(公告)日：2013-05-14
申请号：US12959722
申请日：2010-12-03
CPC分类号： A61B3/1225 , A61B3/102 , G01N21/4795 , G06T7/33 , G06T2207/30004
摘要： Methods of analyzing three dimensional data sets obtained from a sample over time are provided. The methods include aligning first and second volume intensity projection (VIP) images based on at least one landmark in the first and second VIP images. The first and second VIP images are obtained from a first three dimensional data set obtained from the sample at a first time and a second three dimensional data set obtained from the sample at a second time, respectively.
摘要翻译： 提供了一种随时间分析从样本获得的三维数据集的方法。 所述方法包括基于第一和第二VIP图像中的至少一个地标来对准第一和第二体积强度投影（VIP）图像。 第一和第二VIP图像分别从第一次从样本获得的第一三维数据集和第二次从样本获得的第二三维数据集获得。
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13.发明授权Methods, systems and computer program products for processing images generated using Fourier domain optical coherence tomography (FDOCT) 有权用于处理使用傅立叶域光学相干断层扫描（FDOCT）生成的图像的方法，系统和计算机程序产品公开(公告)号：US08401257B2
公开(公告)日：2013-03-19
申请号：US12016352
申请日：2008-01-18
IPC分类号： G06K9/20
CPC分类号： G01B9/02091 , A61B3/102 , A61B3/117 , A61B5/0066 , A61B5/7207 , A61B5/7257 , G01N21/4795 , G01P3/36 , G06T11/003
摘要： Methods, systems and computer program products for managing frequency domain optical coherence tomography (FDOCT) image resolution. A spectrum used to acquire an image of a subject is calibrated and default dispersion correction parameters are set. Default dispersion management parameters associated with a region of the image of the subject are also set. The image of the subject is acquires after setting the default dispersion correction parameters and the default dispersion management parameters. A quality of the acquired image is compared to a quality metric for the acquired image. The dispersion correction parameters are adjusted if the quality of the acquired image does not meet or exceed the quality metric for the acquired image. The acquired image is reprocesses based on the adjusted dispersion correction parameters. The steps of comparing, adjusting and reprocessing are repeated until the acquired image meets or exceeds the quality metric for the acquired image.
摘要翻译： 用于管理频域光学相干断层扫描（FDOCT）图像分辨率的方法，系统和计算机程序产品。 用于获取被摄体图像的光谱被校准，并且设置默认色散校正参数。 还设置与被摄体的图像的区域相关联的默认色散管理参数。 在设置默认色散校正参数和默认色散管理参数后，获取被摄体的图像。 将所获取的图像的质量与所获取的图像的质量度量进行比较。 如果所获取的图像的质量不满足或超过所获取的图像的质量度量，则调整色散校正参数。 所获取的图像基于经调整的色散校正参数进行再处理。 重复比较，调整和重新处理的步骤，直到所获取的图像满足或超过所获取的图像的质量度量。
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14.发明授权公开(公告)号：US08374684B2
公开(公告)日：2013-02-12
申请号：US13281561
申请日：2011-10-26
IPC分类号： A61B6/00
CPC分类号： A61B3/14 , A61B3/1005 , A61B3/102 , A61B3/1208 , A61B3/1225 , A61B3/125 , G01B9/02028 , G01B9/0205 , G01B9/02057 , G01B9/02089 , G01B9/02091 , G01B2290/25 , G01B2290/35 , G01N21/4795
摘要： Portable optical coherence tomography (OCT) devices including at least one mirror configured to scan at least two directions are provided. The portable OCT devices are configured to provide a portable interface to a sample that can be aligned to the sample without repositioning the sample. Related systems are also provided.
摘要翻译： 提供了包括配置成扫描至少两个方向的至少一个反射镜的便携式光学相干断层摄影（OCT）装置。 便携式OCT设备被配置为向样本提供便携式接口，该样本可以与样品对准而不重新定位样品。 还提供了相关系统。
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15.发明申请公开(公告)号：US20120101373A1
公开(公告)日：2012-04-26
申请号：US13281561
申请日：2011-10-26
IPC分类号： A61B6/00
CPC分类号： A61B3/14 , A61B3/1005 , A61B3/102 , A61B3/1208 , A61B3/1225 , A61B3/125 , G01B9/02028 , G01B9/0205 , G01B9/02057 , G01B9/02089 , G01B9/02091 , G01B2290/25 , G01B2290/35 , G01N21/4795
摘要： Portable optical coherence tomography (OCT) devices including at least one mirror configured to scan at least two directions are provided. The portable OCT devices are configured to provide a portable interface to a sample that can be aligned to the sample without repositioning the sample. Related systems are also provided.
摘要翻译： 提供了包括配置成扫描至少两个方向的至少一个反射镜的便携式光学相干断层摄影（OCT）装置。 便携式OCT设备被配置为向样本提供便携式接口，该样本可以与样品对准而不重新定位样品。 还提供了相关系统。
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16.发明授权公开(公告)号：US07990541B2
公开(公告)日：2011-08-02
申请号：US12551782
申请日：2009-09-01
IPC分类号： G01B9/02
CPC分类号： G01B9/02044 , A61B3/102 , A61B3/1225 , A61B5/0066 , G01B9/02004 , G01B9/02007 , G01B9/02008 , G01B9/02091 , G01B2290/45 , G01N21/4795
摘要： Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.
摘要翻译： 频域光学相干成像系统在光源和光学检测器之间具有光源，光学检测器和光传输路径。 光源和光学检测器之间的光传输路径降低了成像系统的有效线宽。 光源可以是宽带源，并且光传输路径可以包括周期性滤光器。
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17.发明申请Optical Coherence Imaging Systems Having a Mechanism for Shifting Focus and Scanning Modality and Related Adapters 有权具有移动焦点和扫描模式的机制的光学相干成像系统及相关适配器公开(公告)号：US20100321636A1
公开(公告)日：2010-12-23
申请号：US12854516
申请日：2010-08-11
摘要： Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.
摘要翻译： 本发明的一些实施例提供用于后置成像系统的适配器。 适配器包括被配置为使后部成像系统适合作为前成像系统操作的镜片组。 本文还提供了相关的光学相干断层扫描系统和前置成像系统。
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18.发明授权Optical coherence imaging systems having a mechanism for shifting focus and scanning modality and related adapters 有权光学相干成像系统具有用于移动聚焦和扫描模态的机制以及相关适配器公开(公告)号：US07830525B2
公开(公告)日：2010-11-09
申请号：US11930865
申请日：2007-10-31
IPC分类号： G01B9/02
摘要： Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.
摘要翻译： 本发明的一些实施例提供用于后置成像系统的适配器。 适配器包括被配置为使后部成像系统适合作为前成像系统操作的镜片组。 本文还提供了相关的光学相干断层扫描系统和前置成像系统。
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19.发明申请OPTICAL COHERENCE IMAGING SYSTEMS HAVING A REDUCED EFFECTIVE LINEWIDTH AND METHODS OF USING THE SAME 有权具有减少有效线条的光学相干成像系统及其使用方法公开(公告)号：US20090316160A1
公开(公告)日：2009-12-24
申请号：US12551782
申请日：2009-09-01
IPC分类号： G01J3/45
CPC分类号： G01B9/02044 , A61B3/102 , A61B3/1225 , A61B5/0066 , G01B9/02004 , G01B9/02007 , G01B9/02008 , G01B9/02091 , G01B2290/45 , G01N21/4795
摘要： Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.
摘要翻译： 频域光学相干成像系统在光源和光学检测器之间具有光源，光学检测器和光传输路径。 光源和光学检测器之间的光传输路径降低了成像系统的有效线宽。 光源可以是宽带源，并且光传输路径可以包括周期性滤光器。
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20.发明申请Spectral Domain Phase Microscopy (SDPM) Dual Mode Imaging Systems and Related Methods and Computer Program Products 有权光谱域相位显微镜（SDPM）双模式成像系统及相关方法和计算机程序产品公开(公告)号：US20090237673A1
公开(公告)日：2009-09-24
申请号：US12477949
申请日：2009-06-04
CPC分类号： A61B3/13 , A61B3/102 , A61B5/0066 , A61B5/0073 , G01B9/02018 , G01B9/02021 , G01B9/02025 , G01B9/02044 , G01B9/02083 , G01B9/0209 , G01B9/02091 , G01N21/4795
摘要： Some embodiments of the present invention provide optical coherence tomography systems including an OCT engine and a processor. The OCT engine is configured to provide both standard OCT imaging and spectral domain phase microscopy (SDPM) imaging. The processor is coupled to the OCT engine and is configured to use a first signal processing method when the OCT engine is configured to provide standard OCT imaging and a second signal processing method when the OCT engine is configured to provide SDPM imaging. Related methods and computer program products are also provided.
摘要翻译： 本发明的一些实施例提供包括OCT引擎和处理器的光学相干断层摄影系统。 OCT引擎配置为提供标准OCT成像和光谱域相位显微镜（SDPM）成像。 处理器耦合到OCT引擎，并且被配置为当OCT引擎配置为提供标准OCT成像时使用第一信号处理方法，并且当OCT引擎配置为提供SDPM成像时，使用第二信号处理方法。 还提供了相关方法和计算机程序产品。
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