公开(公告)号：US20130337473A1

公开(公告)日：2013-12-19

申请号：US13888299

申请日：2013-05-06

Applicant: The Regents of the University of California

Inventor： Edward L. Nelson ,  Trisha M. Westerhof ,  Mark Bachman ,  Guann-Pyng Li

IPC: G01N33/574

CPC classification number: G01N33/574 ,  G01N33/56966 ,  G01N33/56972 ,  G01N33/56977 ,  G01N33/57438

Abstract: Cell identification systems and methods using micropallet arrays are disclosed. According to one embodiment, a cell identification strategy involves detecting the expression patterns of markers that are expressed on cells to uniquely identify different cell populations within heterogeneous mixtures of cells. The cell markers may be on the cell surface or intracellular in location. The cell markers are interrogated using monoclonal antibodies (mAbs) that are directly conjugated to flourophores. The mAb-flourophore conjugates are used to detect the presence or absence and relative level of expression of each of the cell markers using laser scanning confocal microscopy.

Abstract translation: 公开了使用微孔阵列的细胞鉴定系统和方法。 根据一个实施方案，细胞鉴定策略涉及检测在细胞上表达的标志物的表达模式以唯一地鉴定细胞异种混合物内的不同细胞群。 细胞标志物可以在细胞表面上或细胞内的位置。 使用直接与荧光体缀合的单克隆抗体（mAb）来询问细胞标记物。 使用激光扫描共聚焦显微镜，使用mAb-荧光共轭物来检测每种细胞标记物的存在或不存在和相对的表达水平。

公开(公告)号：US11526827B2

公开(公告)日：2022-12-13

申请号：US16588634

申请日：2019-09-30

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Guann-Pyng Li ,  Michael John Klopfer ,  Sergio Gago-Masague ,  Richard P. Donovan ,  Yutian Ren

IPC: G06Q10/06 ,  G06Q50/06 ,  G06Q50/04 ,  G05B23/02 ,  G01R22/10

Abstract: Non-intrusive monitoring and workflow assessment to optimize manufacturing environments are described herein. The systems and method combines computer vision and energy load disaggregation to track worker activity and equipment usage and status. These events are then correlated to optimize workflows and energy efficiency.

公开(公告)号：US11331663B2

公开(公告)日：2022-05-17

申请号：US16168020

申请日：2018-10-23

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Mark Bachman ,  Sarkis Babikian ,  Guann-Pyng Li

IPC: B01L3/00 ,  B01L9/00 ,  B81B7/00 ,  B81C1/00 ,  B23K1/00 ,  B23K101/42

Abstract: A microfluidic component package that is readily integratable within a microfluidic system.

公开(公告)号：US10580604B2

公开(公告)日：2020-03-03

申请号：US15458444

申请日：2017-03-14

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Mark Bachman ,  Guann-Pyng Li ,  Yang Zhang ,  Minfeng Wang

IPC: H01H1/00 ,  H01H50/32 ,  B81B3/00 ,  H01H50/00 ,  H01H50/44 ,  H01H50/58

Abstract: Micro-electromagnetically actuated latched miniature relay switches formed from laminate layers comprising a spring and magnet, electromagnetic coils, magnetic latching material, and transmission line with contacts. Preferably the miniature relay switches transmit up to about 50 W of DC or AC line power, and carry up to about 10 A of load current, with an overall volume of less than about 100 mm3. In addition to switching large power, the device preferably requires less than 3 V to actuate, and has a latching feature that retains the switch state after actuation without the need for external applied voltage or current.

公开(公告)号：US10553358B2

公开(公告)日：2020-02-04

申请号：US15499756

申请日：2017-04-27

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Mark Bachman ,  Guann-Pyng Li

IPC: H01L29/06 ,  H01G4/10 ,  H01L23/64 ,  H01L23/50

Abstract: An electronic substrate or interposer comprising nanoporous films, such as anodic aluminum oxide, containing vertically etched openings (“vias”) that are filled with a conductive material, forming a high density collection of vertically oriented vias that conduct electricity from one side of the substrate to the other.

公开(公告)号：US20170316881A1

公开(公告)日：2017-11-02

申请号：US15499756

申请日：2017-04-27

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Mark Bachman ,  Guann-Pyng Li

IPC: H01G4/10 ,  H01L29/06 ,  H01L23/50 ,  H01L23/64

Abstract: An electronic substrate or interposer comprising nanoporous films, such as anodic aluminum oxide, containing vertically etched openings (“vias”) that are filled with a conductive material, forming a high density collection of vertically oriented vias that conduct electricity from one side of the substrate to the other.

公开(公告)号：US09601280B2

公开(公告)日：2017-03-21

申请号：US14547426

申请日：2014-11-19

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Mark Bachman ,  Guann-Pyng Li ,  Yang Zhang ,  Minfeng Wang

IPC: H01H1/00 ,  B81B3/00 ,  H01H50/00

CPC classification number: H01H50/32 ,  B81B3/0054 ,  B81B2201/016 ,  H01H1/0036 ,  H01H50/005 ,  H01H50/44 ,  H01H50/58 ,  H01H2001/0042

Abstract: Micro-electromagnetically actuated latched miniature relay switches formed from laminate layers comprising a spring and magnet, electromagnetic coils, magnetic latching material, and transmission line with contacts. Preferably the miniature relay switches transmit up to about 50 W of DC or AC line power, and carry up to about 10 A of load current, with an overall volume of less than about 100 mm3. In addition to switching large power, the device preferably requires less than 3 V to actuate, and has a latching feature that retains the switch state after actuation without the need for external applied voltage or current.

公开(公告)号：US20150294823A1

公开(公告)日：2015-10-15

申请号：US14547426

申请日：2014-11-19

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Mark Bachman ,  Guann-Pyng Li ,  Yang Zhang ,  Minfeng Wang

IPC: H01H50/32 ,  H01H50/58 ,  H01H51/22 ,  H01H50/44

CPC classification number: H01H50/32 ,  B81B3/0054 ,  B81B2201/016 ,  H01H1/0036 ,  H01H50/005 ,  H01H50/44 ,  H01H50/58 ,  H01H2001/0042

Abstract: Micro-electromagnetically actuated latched miniature relay switches formed from laminate layers comprising a spring and magnet, electromagnetic coils, magnetic latching material, and transmission line with contacts. Preferably the miniature relay switches transmit up to about 50 W of DC or AC line power, and carry up to about 10 A of load current, with an overall volume of less than about 100 mm3. In addition to switching large power, the device preferably requires less than 3 V to actuate, and has a latching feature that retains the switch state after actuation without the need for external applied voltage or current.

Abstract translation: 由包括弹簧和磁体的层压层形成的微电磁致动的小型继电器开关，电磁线圈，磁性闭锁材料和具有触点的传输线。 优选地，小型继电器开关传输高达约50W的DC或AC线路功率，并且承载大约10A的负载电流，总体积小于约100mm 3。 除了切换大功率之外，该装置优选地需要小于3V来致动，并且具有锁定特征，其在致动之后保持开关状态，而不需要外部施加的电压或电流。