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公开(公告)号:US20130288905A1
公开(公告)日:2013-10-31
申请号:US13867848
申请日:2013-04-22
IPC分类号: C12N15/10
CPC分类号: C12N15/1041 , C12N15/1034 , C12N15/1093 , C12Q1/6809 , C40B40/08 , C40B50/06
摘要: Methods are provided for, inter alia, detecting nucleic acid molecules resistant to degradation, such as a plurality of RNA molecules bound to a ribosome, using various technologies including deep sequencing.
摘要翻译: 提供的方法尤其是使用包括深度测序的各种技术来检测抗降解的核酸分子,例如与核糖体结合的多个RNA分子。
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公开(公告)号:US20240309345A1
公开(公告)日:2024-09-19
申请号:US17999756
申请日:2021-06-01
发明人: Luke Gilbert , James Nunez , Jonathan Weissman , Jin Chen
CPC分类号: C12N9/22 , A61K48/005 , A61P31/14 , C12N9/1007 , C07K2319/09 , C12N2310/20
摘要: Provided herein are, inter alia, fusion proteins, compositions and methods for manipulation of genomes of living organisms.
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13.POOLED METHOD FOR HIGH THROUGHPUT SCREENING OF TRANS FACTORS AFFECTING RNA LEVELS 审中-公开
标题翻译: 影响RNA水平的转录因子的高通量筛选的重叠方法公开(公告)号:US20160362684A1
公开(公告)日:2016-12-15
申请号:US15175977
申请日:2016-06-07
IPC分类号: C12N15/10
CPC分类号: C12N15/1086 , B01J2219/00547 , B01J2219/00572 , B01J2219/00585 , B01J2219/00722 , B01J2219/00743 , C12N15/1034 , C40B20/04
摘要: Provided herein are methods directed to multiplexed detection of the modulation of transcriptional activity using perturbation elements.
摘要翻译: 本文提供的方法涉及使用扰动元件多路复用检测转录活性的调节活性。
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公开(公告)号:US09284604B2
公开(公告)日:2016-03-15
申请号:US13900356
申请日:2013-05-22
CPC分类号: C12Q1/6869 , C12Q1/6806 , C12Q1/6809 , C12Q2521/107 , C12Q2527/101 , C12Q2535/122 , C12Q2565/113
摘要: Methods and compositions for identifying a cellular nascent RNA transcript are provided.
摘要翻译: 提供用于鉴定细胞新生RNA转录物的方法和组合物。
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公开(公告)号:US20230212323A1
公开(公告)日:2023-07-06
申请号:US17999762
申请日:2021-06-04
发明人: Luke Gilbert , Jonathan Weissman , James Nunez , Greg Pommier
CPC分类号: C07K19/00 , C12N15/63 , C12N9/22 , C07K2319/09 , C07K2319/80 , C07K2319/85
摘要: Provided herein are, inter alia, compositions and methods for modulating gene expression.
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公开(公告)号:US20230124253A1
公开(公告)日:2023-04-20
申请号:US17816369
申请日:2022-07-29
发明人: Jin Chen , Luke Gilbert , James Nunez , Jonathan Weissman
IPC分类号: C12N15/62 , C12N9/20 , C12N9/10 , C07K14/47 , C12N15/113
摘要: Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms.
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公开(公告)号:US11434491B2
公开(公告)日:2022-09-06
申请号:US17073588
申请日:2020-10-19
发明人: Jin Chen , Luke Gilbert , James Nunez , Jonathan Weissman
IPC分类号: C12N15/62 , C07K14/47 , C12N9/10 , C12N9/20 , C12N15/113
摘要: Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms.
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公开(公告)号:US20210139918A1
公开(公告)日:2021-05-13
申请号:US17073588
申请日:2020-10-19
发明人: Jin Chen , Luke Gilbert , James Nunez , Jonathan Weissman
IPC分类号: C12N15/62 , C12N15/113 , C12N9/20 , C12N9/10 , C07K14/47
摘要: Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms.
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公开(公告)号:US20160326519A1
公开(公告)日:2016-11-10
申请号:US15017214
申请日:2016-02-05
CPC分类号: C12N15/1041 , C12N15/1034 , C12N15/1093 , C12Q1/6809 , C40B40/08 , C40B50/06
摘要: Methods are provided for, inter alia, detecting nucleic acid molecules resistant to degradation, such as a plurality of RNA molecules bound to a ribosome, using various technologies including deep sequencing.
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