公开(公告)号：US20140148900A1

公开(公告)日：2014-05-29

申请号：US14137239

申请日：2013-12-20

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Tueng T. Shen

IPC: A61K9/00 ,  A61K31/496

CPC classification number: A61K9/0051 ,  A61F2/16 ,  A61F2/1694 ,  A61F9/0017 ,  A61F2002/16901 ,  A61F2250/0068 ,  A61K31/496 ,  A61K31/70 ,  A61K31/711 ,  Y10T29/53987

Abstract: Intraocular devices having a drug delivery construct attached thereto, and methods for using the devices for intraocular drug delivery and the treatment and/or prevention of conditions.

Abstract translation: 具有附着于其上的药物递送构建体的眼内装置以及使用该装置进行眼内药物递送的方法以及治疗和/或预防病症。

公开(公告)号：US20250163290A9

公开(公告)日：2025-05-22

申请号：US18465867

申请日：2023-09-12

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xiaojie Lin ,  Jonathan Himmelfarb ,  Buddy D. Ratner

IPC: C09D133/26 ,  A61L29/04 ,  A61L29/06 ,  A61L29/08 ,  A61L29/14 ,  C08J3/28

Abstract: Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

公开(公告)号：US11918718B2

公开(公告)日：2024-03-05

申请号：US18056994

申请日：2022-11-18

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Runbang Tang

IPC: B01J20/26 ,  A61M1/16 ,  B01D15/38 ,  B01J20/28

CPC classification number: A61M1/1696 ,  B01D15/3852 ,  B01J20/267 ,  B01J20/268 ,  B01J20/28004

Abstract: The present disclosure features a composition, including molecularly imprinted crosslinked polymers that have been imprinted with trimethylamine N-oxide. The molecularly imprinted crosslinked polymers have specific binding sites for trimethylamine N-oxide, and a trimethylamine N-oxide absorption capacity of at least 0.5 mg/g.

公开(公告)号：US20230014056A1

公开(公告)日：2023-01-19

申请号：US17931474

申请日：2022-09-12

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xiaojie Lin ,  Jonathan Himmelfarb ,  Buddy D. Ratner

IPC: C09D133/26 ,  A61L29/04 ,  A61L29/06 ,  A61L29/08 ,  A61L29/14 ,  C08J3/28

Abstract: Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

公开(公告)号：US11441049B2

公开(公告)日：2022-09-13

申请号：US17435654

申请日：2020-03-13

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xiaojie Lin ,  Jonathan Himmelfarb ,  Buddy D. Ratner

IPC: C09D133/26 ,  C08J3/28 ,  A61L29/06 ,  A61L29/04 ,  A61L29/08 ,  A61L29/14

Abstract: Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

公开(公告)号：US20150045643A1

公开(公告)日：2015-02-12

申请号：US14028303

申请日：2013-09-16

Applicant: University of Washington through its Center for Commercialization

Inventor： Cagdas Varel ,  Tueng T. Shen ,  Karl F. Bohringer ,  Brian Otis ,  Buddy D. Ratner

IPC: A61B3/16 ,  A61B5/053 ,  A61B17/34 ,  A61B5/00

CPC classification number: A61B3/16 ,  A61B5/0004 ,  A61B5/0538 ,  A61B5/6821 ,  A61B5/686 ,  Y10T29/49155

Abstract: The present technology relates generally to intraocular pressure (“IOP”) monitoring systems and associated devices and methods. In some embodiments, an intraocular pressure monitoring system configured in accordance with the technology comprises an implantable intraocular assembly and an external unit configured to transmit power to and receive data from the intraocular assembly. The intraocular assembly can include an IOP sensing device embedded within a flexible, expandable annular member. The IOP sensing device can include an antenna, a pressure sensor, and a microelectronic device encapsulated by an elastomer.

Abstract translation: 本技术一般涉及眼内压（“IOP”）监测系统及相关设备和方法。 在一些实施例中，根据该技术配置的眼内压监测系统包括可植入眼内组件和被配置为向眼内组件传输电能并从其接收数据的外部单元。 眼内组件可以包括嵌入柔性可扩张环形构件内的IOP感测装置。 IOP感测装置可以包括天线，压力传感器和由弹性体封装的微电子装置。

公开(公告)号：US20140048699A1

公开(公告)日：2014-02-20

申请号：US13870577

申请日：2013-04-25

Applicant: University of Washington through its Center for Commercialization

Inventor： Buddy D. Ratner ,  Edward Lo ,  Christopher Barnes ,  M. Jeanette Stein

IPC: H01J49/26 ,  H01J49/10

CPC classification number: H01J49/26 ,  G01N33/0004 ,  G01N33/02 ,  G01N33/14 ,  G01N33/483 ,  G01N33/49 ,  H01J49/10 ,  H01J49/142

Abstract: Method and system for detecting multiple analytes from a sample material by desorption ionization, mass analysis, and multivariate statistical analysis.

Abstract translation: 通过解吸电离，质量分析和多变量统计分析从样品材料中检测多种分析物的方法和系统。