中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

22 records (took 0.015 seconds)

    MULTI- INJECTION MODE VALVE MODULE
    11.
    发明申请
    MULTI- INJECTION MODE VALVE MODULE 有权

    公开(公告)号：US20210208114A1

    公开(公告)日：2021-07-08

    申请号：US17206994

    申请日：2021-03-19

    Applicant: Waters Technologies Corporation

    Inventor： Sylvain Cormier ,  Richard W. Andrews ,  Peyton C. Beals

    IPC: G01N30/32 ,  G01N30/34 ,  G01N30/20 ,  G01N30/24 ,  G01N30/22 ,  G01N30/86 ,  G01N30/88

    Abstract: A chromatography system includes a gradient delay volume defined as an overall fluid volume between where gradient is proportioned until an inlet of a chromatography column, a pump pumping a flow of gradient; and at least one valve located downstream from the pump, the at least one valve having a plurality of ports including an inlet port that receives the flow of gradient from the pump and an outlet port through which the flow of gradient exits the at least one valve, the at least one valve having at least two positions. A first position of the at least two positions of the at least one valve increases the gradient delay volume of the chromatography system relative to when the at least one valve is in a second position.

    MIXER FOR CHROMATOGRAPHY SYSTEM
    12.
    发明申请
    MIXER FOR CHROMATOGRAPHY SYSTEM 有权

    公开(公告)号：US20210048415A1

    公开(公告)日：2021-02-18

    申请号：US16988942

    申请日：2020-08-10

    Applicant: Waters Technologies Corporation

    Inventor： Peyton C. Beals ,  Sylvain Gilles Cormier ,  Richard Wayne Andrews

    IPC: G01N30/34 ,  B01F13/00 ,  B01F5/06

    Abstract: Described is a mixer for a chromatography system. The mixer includes an inlet manifold channel, an outlet manifold channel and a plurality of transfer channels. The inlet manifold channel has an inlet at a proximal end of the inlet manifold channel for receiving an inlet flow. The transfer channels are fluidly connected between the inlet and outlet manifold channels. The respective fluid connections are distributed along each of the inlet and outlet manifolds channels. The transfer channels have different volumes. The mixer may be formed of a plurality of layer and the layers may be diffusion bonded to each other.

    Chromatographic sample for determining equivalent thermal conditions between liquid chromatography systems
    14.
    发明授权
    Chromatographic sample for determining equivalent thermal conditions between liquid chromatography systems 有权
    用于确定液相色谱系统之间的等温热条件的色谱样品

    公开(公告)号：US09488624B2

    公开(公告)日：2016-11-08

    申请号：US14737812

    申请日：2015-06-12

    Applicant: Waters Technologies Corporation

    Inventor： Richard W. Andrews ,  Peyton C. Beals

    IPC: G01N30/04 ,  G01N30/86 ,  B01D15/42 ,  G01N30/30

    CPC classification number: G01N30/04 ,  B01D15/424 ,  G01N30/8672 ,  G01N2030/047 ,  G01N2030/3007

    Abstract: Described is a method of transferring a chromatographic method between liquid chromatography (LC) systems and a sample for performing the method. The method is based on a determination of an isoretention temperature at which two solutes co-elute. The method enables separations to be performed using different LC systems with reproducible and equivalent results. For example, the method allows for a chromatography method developed for HPLC to be readily transferred to a UPLC system and for a chromatography method developed for a UPLC system to be more readily transferred to a HPLC system. The method addresses LC systems having column ovens of different design in which the internal column temperatures are not equal although the operating temperatures of the column ovens may be accurately controlled to equal values. The retention behavior and resolution of different LC systems is caused to be substantially the same so that equivalent separation results are obtained.

    Abstract translation: 描述了在液相色谱（LC）系统和用于执行该方法的样品之间转移色谱方法的方法。 该方法基于两个溶质共洗脱的等离子体停留温度的测定。 该方法可以使用具有可重现性和等效结果的不同液相色谱系统进行分离。 例如，该方法允许为HPLC开发的色谱方法容易转移到UPLC系统中，并且为UPLC系统开发的色谱方法更容易转移到HPLC系统。 该方法解决了具有不同设计的列炉的LC系统，其中内部柱温度不相等，尽管柱式炉的操作温度可以被精确地控制为相等的值。 导致不同LC系统的保持行为和分辨率基本相同，从而获得等效的分离结果。

    Mixer for chromatography system
    16.
    发明授权
    Mixer for chromatography system 有权

    公开(公告)号：US11555805B2

    公开(公告)日：2023-01-17

    申请号：US16988942

    申请日：2020-08-10

    Applicant: Waters Technologies Corporation

    Inventor： Peyton C. Beals ,  Sylvain Gilles Cormier ,  Richard Wayne Andrews

    IPC: G01N30/34 ,  B01F25/432 ,  B01F33/30

    Abstract: Described is a mixer for a chromatography system. The mixer includes an inlet manifold channel, an outlet manifold channel and a plurality of transfer channels. The inlet manifold channel has an inlet at a proximal end of the inlet manifold channel for receiving an inlet flow. The transfer channels are fluidly connected between the inlet and outlet manifold channels. The respective fluid connections are distributed along each of the inlet and outlet manifolds channels. The transfer channels have different volumes. The mixer may be formed of a plurality of layer and the layers may be diffusion bonded to each other.

    METHOD AND APPARATUS FOR INJECTING A CHROMATOGRAPHIC SAMPLE
    20.
    发明申请
    METHOD AND APPARATUS FOR INJECTING A CHROMATOGRAPHIC SAMPLE 审中-公开

    公开(公告)号：US20190170706A1

    公开(公告)日：2019-06-06

    申请号：US16098280

    申请日：2017-05-04

    Applicant: Waters Technologies Corporation

    Inventor： Martin Gilar ,  Richard W. Andrews ,  Peyton C. Beals ,  Thomas McDonald ,  Keith Fadgen ,  Jordan Kornfeld ,  Geoff Gerhardt ,  Sylvain Cormier

    IPC: G01N30/24 ,  G01N30/06

    Abstract: A method for injecting a diluted sample in a chromatography system includes merging a flow of a sample and a flow of a diluent to form a flow of a diluted sample. A dilution ratio of the diluted sample equals a sum of the volumetric flow rates of the sample and the diluent divided by the volumetric flow rate of the sample. The diluted sample is stored in a holding element before injection into a chromatographic system flow. Sample dilution occurs under low pressure relative to the chromatographic flow thereby allowing lower pressure sample and diluent syringes to be used. Other benefits include reduced compressibility and a reduction in leaks due to the lower pressure operation. The method avoids problems associated with manual techniques which can introduce errors due, for example, to loss of sample, sample precipitation and adsorption of sample to vials.

Patent Agency Ranking