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    METHOD AND APPARATUS FOR CONTROL OF MASS COMPOSITION OF MOBILE PHASE
    1.
    发明申请
    METHOD AND APPARATUS FOR CONTROL OF MASS COMPOSITION OF MOBILE PHASE 审中-公开

    公开(公告)号：US20200088695A1

    公开(公告)日：2020-03-19

    申请号：US16693797

    申请日：2019-11-25

    Applicant: Waters Technologies Corporation

    Inventor： Joshua A. Shreve ,  Peter Kirby

    IPC: G01N30/04 ,  B01D15/16 ,  G01N30/34

    Abstract: Described are a method and an apparatus for delivering a fluid having a desired mass composition. According to the method, temperatures of the fluids to be mixed are sensed and the densities of the fluids at the sensed temperatures are determined. The volume of each fluid is determined so that a mixture of the fluids at the sensed temperatures has the desired mass composition. The determined volumes of the fluids are combined to create the mixture. In one option, combining the determined volumes includes metering flows of the fluids sequentially into a common fluid channel. Alternatively, combining the determined volumes includes controlling a flow rate of each of the fluids and directing the fluids into a common fluid channel.

    Carbon dioxide based chromatography systems including multiple pressure control devices
    2.
    发明授权
    Carbon dioxide based chromatography systems including multiple pressure control devices 有权

    公开(公告)号：US10359403B2

    公开(公告)日：2019-07-23

    申请号：US15909275

    申请日：2018-03-01

    Applicant: Waters Technologies Corporation

    Inventor： Michael O. Fogwill ,  Joshua A. Shreve ,  Michael Eggertson ,  Thomas S. McDonald ,  Joseph D. Michienzi ,  Abhijit Tarafder

    IPC: G01N30/32 ,  G01N30/72 ,  G01N30/34 ,  B01D15/16 ,  B01D15/40

    Abstract: The present disclosure relates to methodologies, systems and apparatus for controlling pressure in a CO2-based chromatography system. A first pressure control element is located downstream of a CO2-based chromatography system and is disposed to control pressure within the column. A split restrictor is located downstream of the primary pressure control element and is disposed to divert a portion of the mobile phase flow to a detector. A second pressure control element is located downstream of the split restrictor and is disposed to control pressure at the restrictor. While the first pressure control element executes a pressure-controlled gradient separation, the second pressure control element maintains a constant pressure at the restrictor. During a composition-programmed gradient separation, the second control element maintains a constant pressure at the split restrictor while the first pressure control element maintains a constant average density across the column.

    Passive column pre-heater for use in chromatographic systems
    3.
    发明授权
    Passive column pre-heater for use in chromatographic systems 有权

    公开(公告)号：US10345276B2

    公开(公告)日：2019-07-09

    申请号：US15303321

    申请日：2015-04-10

    Applicant: Waters Technologies Corporation

    Inventor： Joshua A. Shreve ,  Kurt D. Joudrey

    IPC: G01N30/30 ,  G01N1/44

    Abstract: A passive pre-heater assembly includes a thermally conductive heat-spreading block and a plurality of passive pre-heaters in thermally conductive communication with the heat-spreading block. The plurality of the pre-heaters exchanges heat with the thermally conductive heat-spreading block. Each pre-heater includes a thermally conductive base in thermal communication with the heat-spreading block, and a plurality of thermally conductive fins is in thermal communication with the thermally conductive base. The plurality of fins of each pre-heater exchanges heat convectively with ambient air and conductively with the thermally conductive base of that pre-heater. A given one of the passive pre-heaters further comprises a tube in thermally conductive contact with the thermally conductive base of the given passive pre-heater. The thermally conductive heat-spreading block exchanges heat with a fluid passing through the tube of the given passive pre-heater.

    Modular solenoid valve kits and associated methods
    5.
    发明授权
    Modular solenoid valve kits and associated methods 有权
    模块化电磁阀套件及相关方法

    公开(公告)号：US09546739B2

    公开(公告)日：2017-01-17

    申请号：US14381973

    申请日：2013-03-07

    Applicant: Waters Technologies Corporation

    Inventor： Joshua A. Shreve ,  Steven D. Trudeau ,  Paul Keenan

    IPC: F16K27/02 ,  F16K31/06 ,  G01N30/36 ,  F16K1/34 ,  F16K1/38 ,  G01N30/32

    CPC classification number: F16K27/0281 ,  F16K1/34 ,  F16K1/38 ,  F16K27/029 ,  F16K31/0655 ,  G01N30/36 ,  G01N2030/328 ,  Y10T137/0491 ,  Y10T137/5283 ,  G01N30/32 ,  B01D15/40

    Abstract: Exemplary embodiments are directed to modular solenoid valve kits and associated methods, generally involving a valve body that includes a plurality of actuator section components and a plurality of head section components. The plurality of actuator section components includes a drive solenoid, a solenoid return spring, a stroke calibration collar and an actuator-to-head calibration collar. The plurality of head section components includes a needle, a stem return spring, a seal and a seat. The plurality of actuator section components and head section components are adapted to be interchanged to create a pull-through normally open valve, a pull-through normally closed valve, a push-in normally open valve and a push-in normally closed valve. That is, the kits and methods allow for modification of one valve type (e.g., a pull-through normally open valve, a pull-through normally closed valve, a push-in normally open valve and a push-in normally closed valve) into a different type.

    Abstract translation: 示例性实施例涉及模块化电磁阀套件和相关联的方法，通常涉及包括多个致动器部件部件和多个头部部件部件的阀体。 多个致动器部件包括驱动螺线管，螺线管复位弹簧，行程校准轴环和致动器至头部校准轴环。 多个头部部件包括针，杆复位弹簧，密封件和座。 多个致动器部件和头部部件适于互换以产生拉通常开阀，拉通常闭阀，推入常开阀和推入常闭阀。 也就是说，套件和方法允许修改一种阀类型（例如，通过常开阀，拉通常闭阀，推入式常开阀和推入式常闭阀）到 不同的类型

    BACK PRESSURE REGULATION
    6.
    发明申请
    BACK PRESSURE REGULATION 审中-公开
    后压调节

    公开(公告)号：US20150083947A1

    公开(公告)日：2015-03-26

    申请号：US14382603

    申请日：2013-03-04

    Applicant: Waters Technologies Corporation

    Inventor： Joshua A. Shreve ,  Edwin Denecke ,  Robert A. Jencks

    IPC: F16K1/38 ,  G01N30/60 ,  F16K25/00

    CPC classification number: F16K1/385 ,  B01D15/40 ,  F16K25/005 ,  F16K31/0655 ,  G01N30/60

    Abstract: The invention generally provides a dynamic back pressure regulator. In an exemplary embodiment, the back pressure regulator includes an inlet, an outlet, a seat disposed between the inlet and the outlet and defining at least part of a fluid pathway, and a needle displaceable relative to the seat to form a restriction region therebetween for restricting fluid flow between the inlet and the outlet. In some embodiments, the needle can include a corrosion and/or erosion resistant polymer tip.

    Abstract translation: 本发明通常提供一种动态背压调节器。 在示例性实施例中，背压调节器包括入口，出口，设置在入口和出口之间并限定流体通道的至少一部分的座，以及可相对于座移动的针，以在其间形成限制区域， 限制入口和出口之间的流体流动。 在一些实施例中，针可以包括耐腐蚀和/或耐腐蚀的聚合物尖端。

    DEVICE CAPABLE OF PRESSURIZATION AND ASSOCIATED SYSTEMS AND METHODS
    7.
    发明申请
    DEVICE CAPABLE OF PRESSURIZATION AND ASSOCIATED SYSTEMS AND METHODS 有权
    可加压和相关系统的设备和方法

    公开(公告)号：US20150040992A1

    公开(公告)日：2015-02-12

    申请号：US14381971

    申请日：2013-03-07

    Applicant: Waters Technologies Corporation

    Inventor： Joshua A. Shreve ,  Kurt Joudrey ,  John Angelosanto

    IPC: F17C1/00

    CPC classification number: G01N30/02 ,  B01D15/163 ,  B01D15/40 ,  F17C1/00 ,  G01N30/32 ,  G01N30/36 ,  G01N30/466 ,  G01N2030/027 ,  Y02P20/544 ,  Y10T137/0396 ,  Y10T137/86027 ,  Y10T137/86035 ,  Y10T137/87314 ,  Y10T137/87507 ,  Y10T137/87917 ,  Y10T137/87925

    Abstract: Exemplary embodiments are directed to devices, methods and systems capable of pressurization, generally involving a flow system that includes a pressurized reservoir, at least one pump including a pump control valve, an outlet port, a shut-off valve and a vent valve. The flow system is configured to be pressurized. The shut-off valve is disposed between the pressurized reservoir and the at least one pump. The vent valve is disposed between the at least one pump and the outlet port. The shut-off valve, the vent valve and the pump control valve of the at least one pump are configured to actuate in a coordinated manner to control a pressurization of the flow system. Exemplary embodiments are further directed to devices, methods and systems for column switching, generally including at least a first column, a second column and a column switching valve.

    Abstract translation: 示例性实施例涉及能够加压的装置，方法和系统，通常包括包括加压储存器的流动系统，至少一个泵，包括泵控制阀，出口，截止阀和排气阀。 流动系统构造成加压。 截止阀设置在加压容器和至少一个泵之间。 排气阀设置在至少一个泵和出口之间。 至少一个泵的截止阀，排气阀和泵控制阀被构造成以协调的方式致动以控制流动系统的加压。 示例性实施例进一步涉及用于列切换的装置，方法和系统，通常包括至少第一列，第二列和列切换阀。

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