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19 条记录 (耗时 0.022 秒)

    Method for micropatterning a substrate and a patterned substrate formed thereof
    11.
    发明授权
    Method for micropatterning a substrate and a patterned substrate formed thereof 有权

    公开(公告)号：US10272657B2

    公开(公告)日：2019-04-30

    申请号：US13881000

    申请日：2011-10-25

    申请人： Haiyang Yu ,  Lay Poh Tan

    发明人： Haiyang Yu ,  Lay Poh Tan

    IPC分类号： C03C15/00 ,  C03C25/68 ,  B32B37/00 ,  A61L27/50 ,  G01N33/543 ,  B32B38/10

    摘要： A method of micropatterning a substrate is provided. The method comprises providing a template substrate having a patterned surface inked with a composition of interest; contacting the patterned surface with an intermediate substrate, thereby transferring the composition to the surface of the intermediate substrate; contacting the surface of the intermediate substrate comprising the composition with the substrate; and removing the intermediate substrate by dissolution using a solvent. A patterned substrate formed using the method, as well as a biosensor comprising the patterned substrate is also provided.

    Systems and methods for freezing data
    15.
    发明授权
    Systems and methods for freezing data 有权
    用于冻结数据的系统和方法

    公开(公告)号：US08577923B2

    公开(公告)日：2013-11-05

    申请号：US12687301

    申请日：2010-01-14

    申请人： Jianzhuo Shi ,  Haiyang Yu

    发明人： Jianzhuo Shi ,  Haiyang Yu

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30522 ,  G06F17/30362 ,  G06Q40/02

    摘要： In one embodiment the present invention includes a computer-implemented for determining whether or not a data object is frozen. The method comprises accessing, by a user on a computer, a first data object of a plurality of data objects in one or more computer software applications. The plurality of data objects are assigned to a plurality of entities, where each entity specifies a category, and each of the plurality of data objects belong to a specific entity. The method determines if the first data object is frozen based on a relationship between the first entity and a second entity.

    摘要翻译： 在一个实施例中，本发明包括用于确定数据对象是否被冻结的计算机实现。 该方法包括由计算机上的用户访问一个或多个计算机软件应用中的多个数据对象的第一数据对象。 多个数据对象被分配给多个实体，其中每个实体指定类别，并且多个数据对象中的每一个属于特定实体。 该方法基于第一实体和第二实体之间的关系确定第一数据对象是否被冻结。

    Systems and Methods for Freezing Data
    16.
    发明申请
    Systems and Methods for Freezing Data 有权
    冻结数据的系统和方法

    公开(公告)号：US20110153672A1

    公开(公告)日：2011-06-23

    申请号：US12687301

    申请日：2010-01-14

    申请人： Jianzhuo Shi ,  Haiyang Yu

    发明人： Jianzhuo Shi ,  Haiyang Yu

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30522 ,  G06F17/30362 ,  G06Q40/02

    摘要： In one embodiment the present invention includes a computer-implemented for determining whether or not a data object is frozen. The method comprises accessing, by a user on a computer, a first data object of a plurality of data objects in one or more computer software applications. The plurality of data objects are assigned to a plurality of entities, where each entity specifies a category, and each of the plurality of data objects belong to a specific entity. The method determines if the first data object is frozen based on a relationship between the first entity and a second entity.

    摘要翻译： 在一个实施例中，本发明包括用于确定数据对象是否被冻结的计算机实现。 该方法包括由计算机上的用户访问一个或多个计算机软件应用中的多个数据对象的第一数据对象。 多个数据对象被分配给多个实体，其中每个实体指定类别，并且多个数据对象中的每一个属于特定实体。 该方法基于第一实体和第二实体之间的关系确定第一数据对象是否被冻结。

    Methods and uses of KSR kinase, and mutations thereof
    18.
    发明授权
    Methods and uses of KSR kinase, and mutations thereof 有权
    KSR激酶的方法和用途及其突变

    公开(公告)号：US08900845B2

    公开(公告)日：2014-12-02

    申请号：US13369220

    申请日：2012-02-08

    申请人： Andrey Shaw ,  Jiancheng Hu ,  Haiyang Yu

    发明人： Andrey Shaw ,  Jiancheng Hu ,  Haiyang Yu

    IPC分类号： C12N9/12 ,  C12N9/02

    CPC分类号： C12N9/0069 ,  C07K2319/70 ,  C12N9/1205 ,  G01N2333/90241 ,  G01N2333/9121

    摘要： Mutant KSR proteins are disclosed. The mutants include single amino acid substitutions, leading to either a loss of kinase activity or a loss of scaffolding activity. Also disclosed are methods of screening compounds for inhibitors of KSR kinase activity or KSR scaffolding activity. In some embodiments, the screening methods include protein complementation assays in which nucleic acids encoding fusion constructs comprising enzyme portions and kinase dimerization domains are expressed in cells. Inhibitors of dimerization can be indicated by loss of enzyme activity.

    摘要翻译： 公开了突变型KSR蛋白。 突变体包括单个氨基酸取代，导致激酶活性丧失或脚手架活动丧失。 还公开了筛选KSR激酶活性抑制剂或KSR脚手架活性化合物的方法。 在一些实施方案中，筛选方法包括蛋白质互补测定法，其中编码包含酶部分和激酶二聚化结构域的融合构建体的核酸在细胞中表达。 二聚体的抑制剂可以通过酶活性的丧失来表示。

    IMPLEMENTATION OF A PROCESS BASED ON A USER-DEFINED SUB-TASK SEQUENCE
    19.
    发明申请
    IMPLEMENTATION OF A PROCESS BASED ON A USER-DEFINED SUB-TASK SEQUENCE 审中-公开
    基于用户定义的子任务序列的过程的实现

    公开(公告)号：US20130247051A1

    公开(公告)日：2013-09-19

    申请号：US13001431

    申请日：2010-12-07

    申请人： Fan Sun ,  Mingjian Hu ,  Wang Shiguo ,  Ya Wang ,  Haiyang Yu

    发明人： Fan Sun ,  Mingjian Hu ,  Wang Shiguo ,  Ya Wang ,  Haiyang Yu

    IPC分类号： G06F9/48

    CPC分类号： G06F9/48 ,  G06Q10/00 ,  G06Q10/06 ,  G06Q10/067

    摘要： Various embodiments of systems and methods for implementation of a process based on a user-defined sub-task sequence are described herein. The process includes a set of sub-tasks. A plan owner defines the sequence in which the one or more sub-tasks are to be processed. In one embodiment, the plan owner defines the sequence by setting a fore-task for each sub-task in the sequence. The plan owner also defines a tester who would be processing each sub-task in the set of sub-tasks. A workflow template is triggered for implementing the process. The workflow template loops on the steps defined in the workflow template for processing each sub-task in the set of sub-tasks according to the sequence defined by the plan owner. Each tester after processing the sub-task assigned to them submits the processed sub-task. The process is implemented after all the sub-tasks in the set of sub-tasks have been processed.

    摘要翻译： 这里描述了用于实现基于用户定义的子任务序列的过程的系统和方法的各种实施例。 该过程包括一组子任务。 计划所有者定义要处理一个或多个子任务的顺序。 在一个实施例中，计划所有者通过为序列中的每个子任务设置前任任务来定义序列。 计划所有者还定义了一个测试者，他将处理子任务集中的每个子任务。 触发工作流模板以实现该过程。 工作流模板循环在工作流模板中定义的步骤，用于根据计划所有者定义的顺序处理子任务集中的每个子任务。 每个测试员在处理分配给他们的子任务后，提交处理后的子任务。 该过程在子任务集中的所有子任务已经被处理之后被实现。