公开(公告)号：US11559793B2

公开(公告)日：2023-01-24

申请号：US17510847

申请日：2021-10-26

Applicant: Research Triangle Institute

Inventor： Qinghe Zheng ,  Marty Lail ,  Kelly E. Amato

IPC: B01J23/00 ,  B01J23/78 ,  B01J23/89 ,  B01J35/04 ,  B01J37/03 ,  B01J37/08 ,  F01N3/10 ,  F01N3/28

Abstract: The present disclosure provides perovskite catalytic materials and catalysts comprising platinum-group metals and perovskites. These catalysts may be used as oxygen storage materials with automotive applications, such as three-way catalysts. They are also useful for water or CO2 reduction, or thermochemical energy storage.

公开(公告)号：US20220219992A1

公开(公告)日：2022-07-14

申请号：US17609806

申请日：2020-04-22

Applicant: Research Triangle Institute

Inventor： Jian-Ping SHEN ,  Brian TURK ,  Pradeepkumar SHARMA ,  David DENTON

IPC: C01B32/50 ,  B01J8/24 ,  B01J19/00 ,  B01J23/80 ,  B01J35/00 ,  B01J35/10 ,  C01B3/16

Abstract: A chromium-free catalyst for use in a fluidized bed reactor is described. The catalyst comprises 45-70 wt % Fe2O3, 5-15 wt % CuO, 20-35 wt % Al2O3, 10-20 wt % ZnO, and 1-15 wt % K2CO3. The catalyst has a Davison Index (DI %) of less than or equal to 15. A method for converting carbon monoxide (CO) into carbon-dioxide (CO2) using the catalyst is described. The method includes introducing H2O and CO into a fluidized bed reactor having an operating temperature between about 375° C. and about 450° C. and comprising the chromium free catalyst. The CO conversion is at least 60%.

公开(公告)号：US20220111366A1

公开(公告)日：2022-04-14

申请号：US17510847

申请日：2021-10-26

Applicant: Research Triangle Institute

Inventor： Qinghe Zheng ,  Marty Lail ,  Kelly E. Amato

IPC: B01J23/89 ,  B01J23/00 ,  B01J37/08 ,  F01N3/28 ,  F01N3/10 ,  B01J37/03 ,  B01J23/78 ,  B01J35/04

Abstract: The present disclosure provides perovskite catalytic materials and catalysts comprising platinum-group metals and perovskites. These catalysts may be used as oxygen storage materials with automotive applications, such as three-way catalysts. They are also useful for water or CO2 reduction, or thermochemical energy storage.

公开(公告)号：US11220526B2

公开(公告)日：2022-01-11

申请号：US16090728

申请日：2017-03-23

Applicant: Research Triangle Institute ,  The Regents of the University of California

Inventor： Scott Runyon ,  Danni Harris ,  Rainer Reinscheid ,  Yanyan Zhang ,  Carla Hassler

IPC: C07K5/068 ,  A61K38/00 ,  C07K5/083 ,  C07K5/087 ,  C07K5/097 ,  C07K5/08 ,  C07K5/103 ,  C07K7/06 ,  C07K5/107 ,  A61P25/28 ,  A61P25/30 ,  A61P3/04 ,  A61P25/18

Abstract: Neuropeptide S receptor agonists are provided. The NPS agonists include trimeric, tetrameric, pentameric or hexameric peptidomimetic analogs exhibiting affinity for and activity at the neuropeptide S receptor. The peptidomimetic molecules may be useful in the treatment of disorders, syndromes and conditions mediated by modulation of the neuropeptide S receptor such as substance abuse, narcolepsy, insomnia, obesity, cognitive decline, dementia, Alzheimer's disease, panic disorder, generalized anxiety, PTSD, phobias, schizophrenia and as supportive medication during any kind of cessation program in cognitive behavioral therapy, such as drug addiction, eating disorders and gambling.

公开(公告)号：US20210346661A1

公开(公告)日：2021-11-11

申请号：US17284989

申请日：2019-10-16

Applicant: Research Triangle Institute

Inventor： Leah Marie JOHNSON ,  Ariane VAN DER STRATEN ,  Ginger Denison ROTHROCK ,  Linying Alice LI ,  Ellen LUECKE ,  Natalie GIROUARD ,  Zach Richard DEMKOVICH ,  Sai Archana KROVI

IPC: A61M31/00 ,  A61L27/18 ,  A61L27/54 ,  A61L27/58 ,  A61K9/00

Abstract: A reservoir device comprising an active agent formulation contained within a reservoir is described. The reservoir is defined by a biodegradable, permeable polymer membrane having a thickness of at least 45 μm. The membrane allows for diffusion of an active agent of the formulation there through when positioned subcutaneously in a body of a subject.

公开(公告)号：US11147763B2

公开(公告)日：2021-10-19

申请号：US15770722

申请日：2016-10-25

Applicant: RESEARCH TRIANGLE INSTITUTE

Inventor： Leah Marie Johnson ,  Stephanie Lynn Swarner ,  Ginger Denison Rothrock ,  Ariane Van Der Straten Ponthoz ,  Brian Rhys Stoner

IPC: A61K9/00 ,  A61F6/08 ,  A61M31/00

Abstract: The disclosure provides biomedical devices comprising indicator agents sensitive to the environment of use, methods of using same to enhance adherence to a treatment or usage regimen, and systems for monitoring compliance of use of the biomedical device. The biomedical device may be an intravaginal ring comprised of biocompatible polymeric material having indicator agent incorporated therein capable of producing a detectable change in response to a stimulus within the vaginal environment.

公开(公告)号：US20210317360A1

公开(公告)日：2021-10-14

申请号：US17355828

申请日：2021-06-23

Applicant: Research Triangle Institute

Inventor： Leah Marie Johnson ,  Ginger Denison Rothrock ,  Chasity Antoninette Norton ,  Nicolas Daniel Huffman ,  Jeffrey Brent Mecham

IPC: C09K8/588 ,  E21B33/138 ,  E21B43/20 ,  C09K8/508 ,  C09K8/512 ,  C09K8/516

Abstract: The present disclosure relates to delivery and release systems, such as core-shell particles. An exemplary composition according to the disclosure can include a degradable polymeric shell surrounding a core that includes a crosslinker, which can encompass a metal, such as chromium. The core-shell particles can be provided with a gel-forming polymer, such as a polyacrylamide, into a subterranean reservoir having conditions such that the shell of the core-shell polymer degrades, and the so-released metal is effective to at least partially crosslink the gel-forming polymer to form a gel. The so-formed gel can be effective to control water flow through the subterranean reservoir, such as in relation to a waterflood of the reservoir.

公开(公告)号：US20210309588A1

公开(公告)日：2021-10-07

申请号：US17262490

申请日：2019-07-17

Applicant: Research Triangle Institute ,  University of the Basque Country

Inventor： Iker Aguirrezabal ,  Ignacio Luz Minguez ,  Mustapha Soukri ,  Marty Lail ,  Pedro Luis Arias

IPC: C07C2/32 ,  B01J31/16 ,  B01J35/10

Abstract: Described herein is a catalytic reaction process including introducing one or more gas-phase reactants into a reactor comprising a microporous catalyst having a pore size less than or equal to 2 nm and adjusting the temperature and/or the pressure of the reactor such that one or more of the gas-phase reactants condense within the micropores of the catalyst thereby causing the catalytic reaction to take place in a liquid phase. Additionally, a process for engineering defects on a carboxylate-based metal organic framework (MOF) catalyst is described. The process includes providing a carboxylate-based MOF catalyst; and heating the carboxylate-based MOF catalyst in an inert gas atmosphere at temperatures between about 150° C. and about 900° C.

公开(公告)号：US20210262904A1

公开(公告)日：2021-08-26

申请号：US17184887

申请日：2021-02-25

Applicant: Research Triangle Institute

Inventor： Leah Marie Johnson ,  Nicolas Daniel Huffman

IPC: G01N1/10 ,  C08J9/32 ,  C08K7/28 ,  G01N33/18 ,  G01N33/28

Abstract: Syntactic foams are materials including hollow microspheres distributed throughout a cured polymeric resin. Hollow microspheres within syntactic foams, including collapsible shells that enclose empty cavities, can serve as receptacles to capture environmental constituents upon applied temperature and pressure. An epoxy formulation including of EPON™ 828, HELOXY™ 61, and TETA was combined with hollow glass microspheres with isostatic crush strengths of 300, 3000, and 10,000 psi. Effects of pressure and temperature on the mechanical properties were evaluated via dynamic mechanical analysis. Storage modulus and glass transition temperature depended on formulation. Upon exposure to specific temperature and pressures, the hollow glass spheres embedded within the resin lose mechanical integrity and collapse, resulting in the generation of unencapsulated void spaces, primed to capture embedded liquid. Controllable loss of mechanical integrity enables syntactic foams to serve as on-demand receptacles to retain constituents in the surrounding environment, resulting from externally triggered pressures and temperatures.

公开(公告)号：US10994261B2

公开(公告)日：2021-05-04

申请号：US16250598

申请日：2019-01-17

Applicant: Research Triangle Institute

Inventor： Samuel John Thompson, III ,  Mustapha Soukri

IPC: B01J20/32 ,  B01D53/14 ,  C08G83/00 ,  C08K5/5399 ,  C08J7/00 ,  B01D53/02 ,  C08L1/12 ,  C08L79/02 ,  B01J20/34

Abstract: The present disclosure provides novel solid sorbents synthesized by the reaction of polyamines with polyaldehyde phosphorous dendrimer (P-dendrimer) compounds. The sorbents are highly stable and exhibit rapid reaction kinetics with carbon dioxide, making the sorbents applicable for carbon capture, and can be easily regenerated for further use. The material is stable to aqueous and organic media, as well as strong acid and bases. The sorbent maintains full capacity over extended use. The material can be used for CO2 capture from pure CO2 streams, mixed gas streams, simulated flue gas, and ambient air. Additionally, the material can be adhered to surfaces for reversible CO2 capture applications outside of bulk particle-based processes.