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公开(公告)号：US10257763B2
公开(公告)日：2019-04-09
申请号：US15327764
申请日：2015-07-22
Inventor： Qingjun Zhang , Ser Wah Oh , Yuen Sam Kwok , Sen Gopa , Feng Hong , Pankaj Sharma , Chong Yee Lee , Gim Kerk See
Abstract: There is provided an Advanced Metering Infrastructure (AMI) system including a plurality of gate-ways interconnected by a network comprising a plurality of subnets based on one or more types of networking protocols, each of the plurality of gateways communicatively coupled to or integrated in a metering device; and a concentrator connected to the network for receiving metering data from the metering devices. The concentrator and the plurality of gateways each defines a communication node in the network. In particular, each of the gateways is configured to store a route information comprising at least a primary route information and is operable to route uplink data received based on the route information, the primary route information indicating a predetermined one of the communication nodes for the gateway to route the uplink data to next as a first priority.
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公开(公告)号：US10251568B2
公开(公告)日：2019-04-09
申请号：US14372631
申请日：2013-01-14
Applicant: Agency for Science, Technology and Research
Inventor： Zhihao Chen , Soon Huat Ng , Ju Teng Teo , Xiufeng Yang
IPC: A61B5/02 , A61B5/021 , A61B5/00 , A61B5/0295 , A61B5/11
Abstract: An apparatus, methods and a system for cuffless blood pressure monitoring are provided. The system includes an optical BCG sensor, a PPG sensor, a transceiver and a signal processing device. The BCG sensor optically couples to the subject, acquires BCG signals from the subject, and optically transmits the subject's BCG signals. The PPG sensor optically couples to the subject for acquiring PPG signals from the subject and optically transmits the acquired subject's PPG signals. The transceiver is coupled to the BCG sensor and the PPG sensor for receiving the BCG signals and the PPG signals and generating a BCG electronic signal from the subject's BCG signals and a PPG electronic signal from the subject's PPG signals. And the signal processing device is coupled to the transceiver for receiving the BCG electronic signal and the PPG electronic signal and for monitoring the subject's blood pressure in response to predetermined BCG indicia of the BCG electronic signal and predetermined PPG indicia of the PPG electronic signal.
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公开(公告)号：US10249593B2
公开(公告)日：2019-04-02
申请号：US15310684
申请日：2015-06-22
Applicant: Agency for Science, Technology and Research
Inventor： Sunil Wickramanayaka , Ling Xie , Jerry Jie Li Aw
IPC: H01L23/00 , H01L25/00 , H01L25/065
Abstract: A method for chip on wafer bonding is provided. The method includes the formation of a plurality of posts on at least one of a chip and a wafer, and a like plurality of contacts on the other of the chip and the wafer. After formation, a contact surface of each post is planarized, the respective planarized contact surface having a surface roughness height. A bonding material is then applied to at least one of the chip in a thickness no greater than the surface roughness height of the contact surface. The posts are then temporarily bonded to the contacts using the bonding material to stabilize a position of the chip relative to the wafer for permanent diffusion bonding of the chip to the wafer.
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公开(公告)号：US10246512B2
公开(公告)日：2019-04-02
申请号：US15922921
申请日：2018-03-16
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Cheng-I Wang , Peter Brauer , Siok Ping Yeo , Hwee Ching Tan , John Edward Connolly
Abstract: Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
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公开(公告)号：US20190077988A1
公开(公告)日：2019-03-14
申请号：US16083881
申请日：2017-03-10
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Hong YAN , Jianwei XU
IPC: C09D183/04 , C09D7/63 , D06M15/643
Abstract: The present invention relates to a hydrophobic coating material comprising a plurality of polysiloxanes cross-linked by a cross-linker having at least one unsaturated functional group, a process for preparing said coating, a coated article as well as a process for coating said article. The coating material is prepared by reacting the plurality of polysiloxanes with the cross-linker in the presence of a catalyst. In a preferred embodiment, the unsaturated group of the cross-linker is a vinyl, methacrylate or acrylate group, such as pentaerythitol tetramethacrylate. The coated article may be a fabric.
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Patent Agency Ranking
公开(公告)号：US20190077909A1
公开(公告)日：2019-03-14
申请号：US15699416
申请日：2017-09-08
Applicant: International Business Machines Corporation , AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (ASTAR)
Inventor： Dylan J. BODAY , Willy CHIN , Jeannette M. GARCIA , James L. HEDRICK , Eunice Leong JIAYU , Shrinivas VENKATARAMAN , Zhi Xiang VOO , Rudy J. WOJTECKI , Yi Yan YANG
CPC classification number: C08G64/183 , A61K47/34 , C08G63/64 , C08G64/18 , C08G64/406 , C08G81/00
Abstract: The present disclosure relates to polythioaminals with applications as carriers or delivery vehicles for therapeutic agents or other small molecule cargo. Polythioaminal block copolymer coupled to a therapeutic agent is a polymer-therapeutic conjugate that exhibits higher stability and longer life time in aqueous environments. The polythioaminal block copolymer coupled to a therapeutic agent can be synthesized by reacting hexahydrotriazines with a hydrophobic block precursor, a hydrophilic block precursor, a particle stabilizing segment precursor, and a cargo, such as a therapeutic agent, in a one pot synthesis. The ease of synthesizing the resulting polythioaminal block copolymer coupled to the therapeutic agent while offering the extended stability and polymer life time in aqueous environments make the polythioaminal block copolymer particularly attractive for therapeutic carriers.
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公开(公告)号：US20190055513A1
公开(公告)日：2019-02-21
申请号：US16079070
申请日：2017-02-22
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Say Kong NG , Sow Zong Dawn LEONG , Gek Ling Janice TAN , Kah Hul Brian TEO
IPC: C12N5/00
Abstract: The invention relates to serum-free cell culture medium, wherein the medium either contains maltose as the sole carbohydrate source, or contains maltose and at least one other saccharide as carbohydrate sources. In a preferred embodiment, the additional saccharide is a monosaccharide, preferably glucose, and the medium comprises DMEM-F12. In a preferred embodiment the cells to be cultured may be CHO or HEK293 cells. Also disclosed are methods of growing and/or culturing a cell using the cell culture medium as described herein, methods of increasing protein yield using the cell culture medium as described herein, and kits thereof.
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公开(公告)号：US20190048208A1
公开(公告)日：2019-02-14
申请号：US15671693
申请日：2017-08-08
Applicant: International Business Machines Corporation , Agency for Science, Technology and Research
Inventor： Amos Cahan , Xin Ding , Mareva B. Fevre , James L. Hedrick , Zhen Chang Liang , Nathaniel H. Park , Theodore G. van Kessel , Rudy J. Wojtecki , Yi Yan Yang
IPC: C09D5/14 , C09D161/22 , A01N33/08 , A01N31/16 , C09D181/02 , A01N33/10 , B05D1/02 , B05D1/00 , B29C39/38 , B29C39/26
Abstract: Embodiments are directed to a method of making an antifouling and bactericidal coating with tailorable surface topology. The method includes depositing a layer of branched polyethyleneimine (BPEI) and diamino-functionalized poly(propylene oxide) (PPO) in a mixture of water and organic solvent on a substrate to form a layer of BPEI/PPO. The method includes depositing a layer of glyoxal in a water-containing solution on the layer of BPEI/PPO. The method further includes curing the layer of BPEI/PPO and layer of glyoxal to form a homogenous, glyoxal crosslinked BPEI/PPO coating, where the curing induces local precipitation and alteration of the glyoxal crosslinked BPEI/PPO coating to provide a textured surface.
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公开(公告)号：US20190040136A1
公开(公告)日：2019-02-07
申请号：US16079947
申请日：2017-03-03
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I WANG , Hsueh Ling Janice OH , Siok Ping YEO , Chia Yin LEE
Abstract: Anti-LAG-3 antibodies are disclosed. Also disclosed are compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号：US20190031773A1
公开(公告)日：2019-01-31
申请号：US15987196
申请日：2018-05-23
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , BAYER AKTIENGESELLSCHAFT , BAYER PHARMA AKTIENGESELLSCHAFT
Inventor： Sylvia GRÜNEWALD , Michael STECKEL , Manfred HUSEMANN , Hanna MEYER , Weiping HAN , Zhaobing DING
IPC: C07K16/40 , C12N15/115 , A61P35/00
Abstract: The present invention is related to an antagonist of PYCR1 for the treatment and/or prevention of a neoplastic disease.
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