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公开(公告)号：US20250101372A1
公开(公告)日：2025-03-27
申请号：US18728307
申请日：2023-01-25
Applicant: Chr. Hansen A/S
Inventor： Thomas JANZEN , Ditte Ellegaard CHRISTENSEN , Jesper BROEND , Jeorgos TRIHAAS , Stephanie SERRAULT
Abstract: The invention provides Streptococcus thermophilus mutants, such as DSM22933, which have improved texturizing properties. The strains have: (i) a mutation in the branched chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) gene; (ii) a mutation in the ABC transporter permease protein gene; and/or (iii) a mutation in the peptide deformylase protein gene. The invention, furthermore, relates to compositions, such as a starter culture, comprising one or more of these mutants, to fermented products made using these mutants and to the use of the mutants and compositions of the invention.
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公开(公告)号：US20250011709A1
公开(公告)日：2025-01-09
申请号：US18713313
申请日：2022-11-28
Applicant: Chr. Hansen A/S
Inventor： Furqan Ali , Pravin GADKARI , Surender Kumar DHAYAL
Abstract: The present invention relates to encapsulation of microbial cultures to improve the robustness and stability upon storage. In particular, the present invention relates to dry preparations of microbial cultures, such as lactic acid bacteria (LAB), coated by a fat-matrix that increase survivability and mitigate post-acidification upon storage at ambient temperature for extended periods of time.
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公开(公告)号：US20240407379A1
公开(公告)日：2024-12-12
申请号：US18697902
申请日：2022-10-03
Applicant: Chr. Hansen A/S
Inventor： Hui Han , Mette Oehrstroem
IPC: A23C9/123
Abstract: The present invention is in the field of dairy technology. It relates to methods for producing fermented milk products comprising live bacteria which products have no or low/reduced post-acidification when stored at ambient temperature. The invention furthermore relates to fermented milk products produced by the method.
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公开(公告)号：US20240398714A1
公开(公告)日：2024-12-05
申请号：US18802979
申请日：2024-08-13
Applicant: Chr. Hansen A/S
Inventor： Brigitte Yde , Stig Gunther
IPC: A61K9/48 , A61K35/744
Abstract: The present invention provides a hard capsule comprising an outer and one inner capsule, wherein the outer capsule comprises a hydrophobic liquid and the inner capsule which comprises a composition comprising uncoated microorganisms and optionally at least one desiccant.
The composition may comprise a filtrate composed of viable fecal bacteria useful for fecal microbiota transplantation (FMT) or a mixture of one or more different types of microorganisms isolated from intestinal microbiome, such as bacteria, archaea, virus, or fungi such as yeast.
The composition may comprise a desiccant, preferably a food approved component which is degradable in the gastrointestinal tract. The hydrophobic liquid, if present, is preferably at least one edible oil.
Also provided are methods of treating or preventing a dysbiosis in a human subject, comprising administering to the human subject at least one capsule of the invention.-
公开(公告)号：US20240368532A1
公开(公告)日：2024-11-07
申请号：US18654969
申请日：2024-05-03
Applicant: Chr. Hansen A/S
Inventor： Neda Faraghiparapari , Marie Penderup Jensen , Jakub Kovacs , Anisha Goel
Abstract: Microbial starter cultures. More specifically, a method for preparing a microbial culture such as a lactic acid bacteria (LAB) starter culture wherein at least one microbial strain such as a lactic acid bacteria and at least one inactivated yeast strain is inoculated in a culture medium.
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Patent Agency Ranking
236.发明公开公开(公告)号：US20240334947A1
公开(公告)日：2024-10-10
申请号：US18688225
申请日：2022-08-31
Applicant: Chr. Hansen A/S
Inventor： Christian Jaeckel , Lone Riisberg
IPC: A23C19/032 , A23C13/16 , C12N1/16 , C12N9/20 , C12R1/645
CPC classification number: A23C19/0328 , A23C13/16 , A23C19/0325 , C12N1/165 , C12N9/20 , C12Y301/01003 , C12R2001/645
Abstract: The present invention relates to a Yarrowia strain, preferably a non-genetically modified Yarrowia strain, for the production of a wild-type, non-engineered, microbial lipolytic enzyme with a high specificity for short-chain fatty acids, preferably with a higher specificity for short chain fatty acids than for medium to long chain fatty acids, preferably when compared to a known microbial lipolytic enzyme. This invention is suitable for use in the food industry, preferably in the dairy industry, more preferably in the cheese industry leading, for example, to flavor enhancement or shortening of the ripening times for ripened cheeses.
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公开(公告)号：US20240277788A1
公开(公告)日：2024-08-22
申请号：US18570816
申请日：2022-06-16
Applicant: Chr. Hansen A/S
Inventor： Lea Hübertz Birch Hansen , Beatrice Nielsen
IPC: A61K35/747 , A61K35/00 , A61K35/744 , A61K35/745 , A61P31/04
CPC classification number: A61K35/747 , A61K35/744 , A61K35/745 , A61P31/04 , A61K2035/115
Abstract: The present invention provides evidence that administration of a probiotic product to newborn piglets and during suckling makes the piglets more resilient towards an ETEC challenge post-weaning and after cessation of the probiotic administration. The pigs administered with probiotics pre-weaning were faster at overcoming the ETEC infection by which ETEC counts in feces were significantly faster reduced compared with non-probiotic supplemented pigs. Keywords: Pig, ETEC F18, Probiotic, post-weaning diarrhea, microbiome, immunity
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238.发明公开公开(公告)号：US20240251813A1
公开(公告)日：2024-08-01
申请号：US18565876
申请日：2022-06-10
Applicant: Chr. Hansen A/S
IPC: A23C19/032 , A23C9/12 , A23C9/123 , A23C19/068 , C12N1/20 , C12R1/46
CPC classification number: A23C19/0328 , A23C9/1206 , A23C9/1238 , A23C19/0684 , C12N1/205 , A23V2400/249 , C12R2001/46
Abstract: The present invention relates to a method for producing a fermented milk product (e.g. a pasta filata cheese) with a relatively stable pH value at the end of the fermentation comprising use of lactase in a first step (a) and lactic acid bacteria (LAB) in a further step, characterized by that the LAB are lactose-deficient (Lac(−)) and capable of metabolizing glucose (Glu(+)). The invention further relates to a Streptococcus thermophilus cell CHCC26980 deposited with registration number DSM32600 and a method to obtain a mutant of this strain.
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公开(公告)号：US20240228944A9
公开(公告)日：2024-07-11
申请号：US18254658
申请日：2021-11-29
Applicant: Chr. Hansen A/S
Inventor： Zuzana Mladenovska , Surender Kumar Dhayal , Kim Nielsen
Abstract: The present invention relates to the field of frozen or dry compositions for prokaryotes, in particular fermentative bacteria such as lactic acid bacteria, a method for preparing frozen or dry prokaryotic compositions and compositions which may be prepared by said method. The cells in a cell concentrate are activated by allowing them to ferment a carbohydrate, before freezing and/or drying to provide a product. The hydrophobicity of the cell surface increases during activation, and this has been found to increase the storage stability of the product.
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240.发明公开公开(公告)号：US20240216448A1
公开(公告)日：2024-07-04
申请号：US18554108
申请日：2022-04-04
Applicant: VIXXOL Corporation , Chr. Hansen A/S
Inventor： Sung Chul Yoo , Seon Hwa Kim , Dong Yeop Kim
IPC: A61K35/747 , A61K38/01 , A61P1/02 , A61P31/04
CPC classification number: A61K35/747 , A61K38/014 , A61P1/02 , A61P31/04
Abstract: The present invention relates to a composition for inhibiting biofilm comprising at least one selected from the group consisting of Lactobacillus rhamnosus, its culture medium, its extract and its cell-free supernatant and collagen hydrolysate. Although Lactobacillus rhamnosus can inhibit biofilm formation even as a single agent, the inhibitory ability is significantly increased when it is simultaneously treated with the collagen hydrolysate. The collagen hydrolysate inhibits acid production of Lactobacillus rhamnosus or Streptococcus mutans. Thus, the Lactobacillus rhamnosus and collagen hydrolysate can be usefully used as a composition for inhibiting the production of biofilms, in particular biofilms occurring in the oral cavity and a composition for preventing, alleviating, or treating oral diseases caused by the biofilms.
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