公开(公告)号：US20120268736A1

公开(公告)日：2012-10-25

申请号：US13090016

申请日：2011-04-19

Applicant: David A. Fattal ,  Raymond G. Beausoieil ,  Zhiyong Li

Inventor： David A. Fattal ,  Raymond G. Beausoieil ,  Zhiyong Li

IPC: G01J3/44 ,  B29D11/00 ,  G02B5/18 ,  B82Y20/00

CPC classification number: B82Y20/00 ,  B29D11/00346 ,  B29D11/0074 ,  G02B5/1809 ,  G02B5/1828

Abstract: A configurable grating based on collapsing nano-fingers includes a substrate; and a plurality of bendable nano-fingers supported on the substrate. The nano-fingers may be formed in a regular first array and the nano-fingers may be formed in a spacing that, upon closing at their tops, forms a second array to act as an optical grating or a diagnostic tool. A method of fabricating a configurable optical grating based on collapsing nano-fingers is also disclosed, as well as a method of determining an open or closed state for a plurality of nano-fingers.

Abstract translation: 基于塌陷纳米指的可配置光栅包括基底; 以及支撑在基板上的多个可弯曲的纳米手指。 纳米指可以形成为规则的第一阵列，并且纳米指可以以间隔形成，在其顶部关闭时，形成第二阵列以用作光栅或诊断工具。 还公开了一种基于塌陷纳米手指制造可配置光栅的方法，以及确定多个纳米手指的打开或关闭状态的方法。

公开(公告)号：US20120188539A1

公开(公告)日：2012-07-26

申请号：US13014683

申请日：2011-01-26

Applicant: Michael J. Stuke ,  Shih-Yuan (SY) Wang ,  Zhiyong Li ,  Min Hu ,  Fung Suong Ou ,  Huei Pei Kuo

Inventor： Michael J. Stuke ,  Shih-Yuan (SY) Wang ,  Zhiyong Li ,  Min Hu ,  Fung Suong Ou ,  Huei Pei Kuo

IPC: G01J3/44 ,  B82Y20/00

CPC classification number: B82Y20/00 ,  G01N21/658

Abstract: A nanorod surface enhanced Raman spectroscopy (SERS) apparatus, system and method of SERS using nanorods that are activated with a key. The nanorod SERS apparatus includes a plurality of nanorods, an activator to move the nanorods from an inactive to an active configuration and the key to trigger the activator. The nanorod SERS system further includes a Raman signal detector and an illumination source. The method of SERS using nanorods includes activating a plurality of nanorods with the key, illuminating the activated plurality of nanorods, and detecting a Raman scattering signal when the nanorods are in the active configuration.

Abstract translation: 纳米棒表面增强拉曼光谱（SERS）装置，使用由键激活的纳米棒的SERS的系统和方法。 纳米棒SERS装置包括多个纳米棒，激活剂将纳米棒从非活性构型移动到活性构型，以及触发激活剂的键。 纳米棒SERS系统还包括拉曼信号检测器和照明源。 使用纳米棒的SERS的方法包括用键激活多个纳米棒，照亮激活的多个纳米棒，以及当纳米棒处于活动配置时检测拉曼散射信号。

公开(公告)号：US20120154791A1

公开(公告)日：2012-06-21

申请号：US12846524

申请日：2010-07-29

Applicant: Huei Pei Kuo ,  Zhiyong Li ,  R. Stanley Williams

Inventor： Huei Pei Kuo ,  Zhiyong Li ,  R. Stanley Williams

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/0227 ,  G01J3/26 ,  G01J3/36 ,  G01N21/658

Abstract: A surface enhanced Raman spectroscopy system includes a surface enhanced Raman spectroscopy substrate and a laser source configured to emit light within a spectrum of wavelengths toward a predetermined species on or near the surface enhanced Raman spectroscopy substrate. The system further includes a set of filters positioned to be in optical communication with light scattered after the laser light interacts with the predetermined species. Each of the filters in the set is respectively configured to pass scattered light within a different predetermined narrow band of wavelengths. The system also includes a plurality of photodetectors, where each photodetector is positioned adjacent to a respective one of the filters in the set and is configured to output a signal if the scattered light passes through the respective one of the filters. The set of filters is targeted for detection of characteristic peaks of the predetermined species.

Abstract translation: 表面增强拉曼光谱系统包括表面增强拉曼光谱基板和激光源，该激光源被配置为向表面增强拉曼光谱基板上或附近的预定物质发射波长光谱的光。 该系统还包括一组滤光器，其被定位成在激光与预定物质相互作用之后与散射的光光通信。 集合中的每个滤光器分别被配置成使不同预定的窄波段内的散射光通过。 该系统还包括多个光电检测器，其中每个光电检测器被定位成与集合中的相应一个滤光器相邻，并且被配置为如果散射光通过相应的一个滤光器则输出信号。 该组滤波器用于检测预定种类的特征峰。

公开(公告)号：US20120119315A1

公开(公告)日：2012-05-17

申请号：US13384950

申请日：2010-01-29

Applicant: Fung Suong Ou ,  Huei Pei Kuo ,  Zhiyong Li ,  Min Hu

Inventor： Fung Suong Ou ,  Huei Pei Kuo ,  Zhiyong Li ,  Min Hu

IPC: H01L23/48 ,  H01L21/28 ,  H01L31/0224

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01J3/44 ,  G01N27/12

Abstract: A sensing device (10, 10′) includes a substrate (14), and first and second electrodes (EIC, EICS, EO) established on the substrate (14). The first electrode (EIC, EICS) has a three-dimensional shape, and the second electrode (EO) is electrically isolated from and surrounds a perimeter of the first electrode (EIC, EICS).

Abstract translation: 感测装置（10,10'）包括衬底（14）以及在衬底（14）上建立的第一和第二电极（EIC，EICS，EO）。 第一电极（EIC，EICS）具有三维形状，并且第二电极（EO）与第一电极（EIC，EICS）的周边电隔离并围绕第一电极的周边。

公开(公告)号：US20120113420A1

公开(公告)日：2012-05-10

申请号：US13384456

申请日：2009-09-17

Applicant: Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexander M. Bratkovski

Inventor： Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexander M. Bratkovski

IPC: G01J3/44

CPC classification number: G01N21/658 ,  B82Y15/00 ,  B82Y30/00

Abstract: An electrically driven device (10) for surface enhanced Raman spectroscopy includes a first electrode (16), a substrate (12) positioned proximate to the first electrode (16), a plurality of cone shaped protrusions (12′) formed integrally with or on a substrate surface (S), a Raman signal-enhancing material (14) coated on each protrusion (12′), and a second electrode (18) positioned relative to the first electrode (16) at a predetermined distance, D. Each of the protrusions (12′) has a tip (22) with a radius of curvature, r, ranging from about 0.1 nm to about 100 nm. The second electrode (18) is positioned relative to the first electrode (16) such that the electrodes (16, 18) together produce an electric field (EF) when a voltage bias is applied therebetween. The electric field (EF) has a field distribution that creates a stronger field gradient at a region proximate to the tips (22) than at other portions of the substrate (12).

Abstract translation: 用于表面增强拉曼光谱的电驱动装置（10）包括第一电极（16），靠近第一电极（16）定位的基板（12），与该第一电极（16）一体形成的多个锥形突起 涂覆在每个突起（12'）上的衬底表面（S），拉曼信号增强材料（14）和相对于第一电极（16）以预定距离D定位的第二电极（D）。 突起（12'）具有从约0.1nm至约100nm范围内的具有曲率半径r的尖端（22）。 第二电极（18）相对于第一电极（16）定位，使得当施加电压时，电极（16,18）一起产生电场（EF）。 电场（EF）具有在靠近尖端（22）的区域处比在衬底（12）的其它部分处产生更强的场梯度的场分布。

公开(公告)号：US20120107569A1

公开(公告)日：2012-05-03

申请号：US12916239

申请日：2010-10-29

Applicant: Michael Josef Stuke ,  Zhiyong Li ,  Shih-Yuan Wang ,  Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Lars Helge Thylen

Inventor： Michael Josef Stuke ,  Zhiyong Li ,  Shih-Yuan Wang ,  Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Lars Helge Thylen

IPC: B32B3/30 ,  B05D3/06 ,  B05D3/02 ,  B05D1/36 ,  B05D3/00

CPC classification number: G01N21/658 ,  B81B3/0005 ,  Y10T428/24355 ,  Y10T428/24612

Abstract: A device for Surface Enhanced Raman Scattering (SERS). The device includes a plurality of nanostructures protruding from a surface of a substrate, a SERS active metal disposed on a portion of said plurality of nanostructures, and a low friction film disposed over the plurality of nanostructures and the SERS active metal. The low friction film is to prevent adhesion between the plurality of nanostructures.

Abstract translation: 用于表面增强拉曼散射（SERS）的器件。 该装置包括从衬底表面突出的多个纳米结构，设置在所述多个纳米结构的一部分上的SERS活性金属，以及设置在多个纳米结构和SERS活性金属上的低摩擦膜。 低摩擦膜是为了防止多个纳米结构之间的粘附。

公开(公告)号：US20110269240A1

公开(公告)日：2011-11-03

申请号：US10795730

申请日：2004-03-08

Applicant: Zhang-Lin Zhou ,  Zhiyong Li ,  Sean Xiao-An Zhang

Inventor： Zhang-Lin Zhou ,  Zhiyong Li ,  Sean Xiao-An Zhang

IPC: G01N27/49 ,  C40B60/12 ,  G01N21/64 ,  H01L29/06 ,  C40B40/00 ,  G01N33/20 ,  B82Y99/00 ,  B82Y15/00

CPC classification number: G01N33/54373 ,  B82Y15/00 ,  B82Y30/00 ,  Y10S977/70 ,  Y10S977/742 ,  Y10S977/745 ,  Y10S977/842

Abstract: The present invention is drawn toward a chemical or biological sensor that can comprise a semi-conducting nanowire and a chemical or biological sensing molecule tethered to the semi-conducting nanowire through a spacer group including a hydrophilic reactive group. In one embodiment, the semi-conducting nanowire can be part of an array of like or similar semi-conducting nanowires. Electrical leads can provide an electrical current to the array, and a signal measurement apparatus can be electrically coupled to the array, and can be configured for detecting changes in the electrical current of the array.

Abstract translation: 本发明涉及化学或生物传感器，其可以包括通过包括亲水反应性基团的间隔基团连接到半导体纳米线的半导体纳米线和化学或生物传感分子。 在一个实施例中，半导体纳米线可以是类似或类似的半导体纳米线阵列的一部分。 电引线可以向阵列提供电流，并且信号测量装置可以电耦合到阵列，并且可以被配置为检测阵列的电流的变化。

公开(公告)号：US20110267611A1

公开(公告)日：2011-11-03

申请号：US12772161

申请日：2010-04-30

Applicant: Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

Inventor： Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

IPC: G01J3/44 ,  G01J3/00

CPC classification number: G01J3/44 ,  G01J3/1895 ,  G01N21/658

Abstract: A scattering spectroscopy apparatus, system and method employ guided mode resonance (GMR) and a GMR grating. The apparatus includes a GMR grating having a subwavelength grating, and an optical detector configured to receive a portion of a scattered signal produced by an interaction between an excitation signal and an analyte associated with a surface of the GMR grating. A propagation direction of the received portion of the scattered signal is substantially different from a propagation direction of a GMR-coupled portion of the excitation signal within the GMR grating. The system includes the apparatus and an optical source. The method includes exciting a GMR in a GMR grating, interacting a GMR-coupled portion of the excitation signal with an analyte to produce a scattered signal and detecting a portion of the scattered signal.

Abstract translation: 散射光谱装置，系统和方法采用导模共振（GMR）和GMR光栅。 该装置包括具有亚波长光栅的GMR光栅和配置成接收由激发信号与与GMR光栅的表面相关联的分析物之间的相互作用产生的散射信号的一部分的光学检测器。 散射信号的接收部分的传播方向与GMR光栅内的激励信号的GMR耦合部分的传播方向基本上不同。 该系统包括该装置和光源。 该方法包括激励GMR光栅中的GMR，将激发信号的GMR耦合部分与分析物相互作用以产生散射信号并检测散射信号的一部分。

公开(公告)号：US20110267606A1

公开(公告)日：2011-11-03

申请号：US12771440

申请日：2010-04-30

Applicant: Fung Suong Ou ,  Zhiyong Li ,  Min Hu ,  Wei Wu

Inventor： Fung Suong Ou ,  Zhiyong Li ,  Min Hu ,  Wei Wu

IPC: G01J3/44 ,  G02B1/12

CPC classification number: G02B1/12 ,  G01N21/658

Abstract: A surface-enhanced Raman spectroscopy device includes a substrate, and an ultraviolet cured resist disposed on the substrate. The ultraviolet cured resist has a pattern of cone-shaped protrusions, where each cone-shaped protrusion has a tip with a radius of curvature equal to or less than 10 nm. The ultraviolet cured resist is formed of a predetermined ratio of a photoinitiator, a cross-linking agent, and a siloxane based backbone chain. A Raman signal-enhancing material is disposed on each of the cone-shaped protrusions.

Abstract translation: 表面增强拉曼光谱装置包括基板和设置在基板上的紫外线固化抗蚀剂。 紫外线固化抗蚀剂具有锥形突起的图案，其中每个锥形突起具有等于或小于10nm的曲率半径的尖端。 紫外线固化的抗蚀剂由光引发剂，交联剂和基于硅氧烷的主链以预定比例形成。 拉曼信号增强材料设置在每个锥形突起上。

公开(公告)号：US08044212B2

公开(公告)日：2011-10-25

申请号：US11799147

申请日：2007-04-30

Applicant: Zhang-Lin Zhou ,  Zhiyong Li

Inventor： Zhang-Lin Zhou ,  Zhiyong Li

IPC: C07D235/02

CPC classification number: H01L51/008 ,  B82Y10/00 ,  C07D207/46 ,  G11C2213/14 ,  H01L51/0072 ,  H01L51/0595

Abstract: Various embodiment of the present invention are directed to organic molecules that are reconfigurable under application of an external electric field. One organic molecule embodiment of the present invention has the structure: where L1X1 and L2X2 are optional connector groups, A represents an electron acceptor group, D represents an electron donor group, R and R′ represent spacer molecules, and R1, R2, R3, R4, R5, R6, R7, and R8 represent atoms and hydrocarbons.

Abstract translation: 本发明的各种实施方案涉及在外部电场的应用下可重新配置的有机分子。 本发明的一个有机分子实施方案具有以下结构：其中L1X1和L2X2是任选的连接基团，A代表电子受体基团，D代表电子给体基团，R和R'代表间隔基分子，R1，R2，R3， R4，R5，R6，R7和R8表示原子和烃。