公开(公告)号：US20140250846A1

公开(公告)日：2014-09-11

申请号：US14189684

申请日：2014-02-25

Applicant: RESEARCH TRIANGLE INSTITUTE

Inventor： Howard Jerome WALLS ,  Randall J. Newsome ,  Anthony Clint Clayton ,  Robert W. Yaga ,  David Samuel Ensor

IPC: B01D46/10 ,  A62B23/02

CPC classification number: B01D46/0001 ,  A62B18/02 ,  A62B18/04 ,  A62B18/084 ,  A62B23/025 ,  B01D46/103 ,  B01D46/546 ,  D01D5/0076 ,  D10B2509/00

Abstract: A filtration device including a contoured support having 1) an interior surface, 2) an outside peripheral surface spaced farther from a center of the contoured support than the interior surface, and 3) a rim enclosed and sealed to a perimeter of the contoured support. The filtration device includes macroscopic openings in the contoured support extending from the interior surface to the outside peripheral surface, and a plurality of nanofibers having diameters less than 1 micron. The nanofibers are disposed on the outside peripheral surface of the contoured support, and cover the macroscopic openings to form a filtration medium on the contoured support.

Abstract translation: 一种过滤装置，包括具有1）内表面的轮廓支撑件，2）与内表面相比间隔开比轮廓支撑件的中心更远的外周表面，以及3）封闭并密封到轮廓支撑件的周边的边缘。 过滤装置包括从内表面延伸到外周表面的轮廓支撑件中的宏观开口，以及直径小于1微米的多个纳米纤维。 纳米纤维布置在成型支撑体的外周表面上，并且覆盖宏观开口以在轮廓支撑件上形成过滤介质。

公开(公告)号：US20140225063A1

公开(公告)日：2014-08-14

申请号：US14254631

申请日：2014-04-16

Applicant: Research Triangle Institute

Inventor： ETHAN KLEM ,  JOHN LEWIS

IPC: H01L51/42 ,  H01L51/00

CPC classification number: H01L51/4213 ,  H01L51/0002 ,  H01L51/0046 ,  H01L51/4226 ,  H01L51/4233 ,  Y02E10/549

Abstract: A photodetector includes one or more photodiodes and a signal processing circuit. Each photodiode includes a transparent first electrode, a second electrode, and a heterojunction interposed between the first electrode and the second electrode. Each heterojunction includes a quantum dot layer and a fullerene layer disposed directly on the quantum dot layer. The signal processing circuit is in signal communication each the second electrode. The photodetector may be responsive to wavelengths in the infrared, visible, and/or ultraviolet ranges. The quantum dot layer may be treated with a chemistry that increases the charge carrier mobility of the quantum dot layer.

Abstract translation: 光电检测器包括一个或多个光电二极管和信号处理电路。 每个光电二极管包括透明的第一电极，第二电极和介于第一电极和第二电极之间的异质结。 每个异质结包括量子点层和直接设置在量子点层上的富勒烯层。 信号处理电路每个都是第二电极的信号通信。 光电检测器可以响应于红外线，可见光和/或紫外线范围内的波长。 量子点层可以用增加量子点层的载流子迁移率的化学物质来处理。

公开(公告)号：US20130261467A1

公开(公告)日：2013-10-03

申请号：US13906700

申请日：2013-05-31

Applicant: RESEARCH TRIANGLE INSTITUTE

Inventor： David Dausch ,  James Carlson ,  Kristin Hedgepath Gilchrist

IPC: A61B8/00 ,  A61B8/12

CPC classification number: A61B8/4494 ,  A61B8/12 ,  A61B8/445 ,  A61N7/00 ,  B06B1/0622 ,  Y10T29/42

Abstract: A method and apparatus directed to formation of a connection with an ultrasonic transducer apparatus (UTA) comprising a transducer device having first and second electrodes is provided. The UTA is engaged with an interposer device surface. The interposer device is greater in at least one lateral dimension than and extends laterally outward of the UTA, and comprises at least two laterally-extending conductors. A conductive engagement is formed between the first and second electrodes and respective first ends of the conductors. A connection support substrate is engaged with the interposer device about second ends of the conductors, and includes at least two connective elements for forming a conductive engagement with the respective second ends of the conductors. The UTA is then inserted into a catheter member lumen such that the device plane of the UTA and the at least two connective elements extend axially along the lumen.

Abstract translation: 提供了一种涉及与包括具有第一和第二电极的换能器装置的超声波换能器装置（UTA）形成连接的方法和装置。 UTA与插入器器件表面接合。 所述插入器装置在至少一个横向尺寸上比UTA更大，并且横向向外延伸，并且包括至少两个横向延伸的导体。 在第一和第二电极与导体的相应的第一端之间形成导电接合。 连接支撑衬底围绕导体的第二端与插入器装置接合，并且包括用于与导体的相应第二端形成导电接合的至少两个连接元件。 然后将UTA插入导管部件内腔，使得UTA的装置平面和至少两个连接元件沿着内腔轴向延伸。

公开(公告)号：US20040266804A1

公开(公告)日：2004-12-30

申请号：US10608207

申请日：2003-06-30

Applicant: Research Triangle Institute

Inventor： Monroe E. Wall ,  Mansukh C. Wani ,  Govindarajan Manikumar ,  Michael A. Wall

IPC: C07D491/14 ,  C07D471/02

CPC classification number: C07D471/14

Abstract: Camptothecin analogs having an E-ring ketone are effective anti tumor compounds. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I DNA cleavable complex.

Abstract translation: 具有E环酮的喜树碱类似物是有效的抗肿瘤化合物。 这些化合物抑制酶拓扑异构酶I，并且可以将相关的拓扑异构酶I DNA可切割复合物的DNA烷基化。

公开(公告)号：US20030131609A1

公开(公告)日：2003-07-17

申请号：US10340652

申请日：2003-01-13

Applicant: Research Triangle Institute

Inventor： Rama Venkatasubramanian

IPC: F25B021/02 ,  F25B007/00

CPC classification number: F25B21/02 ,  H01L35/16 ,  H01L35/325

Abstract: A cascade thermoelectric cooler designed to cool to cryogenic temperatures of 30 to 120 K integrates high performancenullhigh-ZT BixSb2nullxTe3 and Bi2Te3nullxSe3-based super-lattice-structure thin-film thermoelectric devices with a bulk-material based thermoelectric cooler including plural cascaded cold stages with each successive cascaded cold stage able to cool to a progressively lower temperature. Each cold stage in the bulk-material thermoelectric cooler includes a heat source plate, a heat sink plate, a p-type thermoelectric, and a n-type thermoelectric. Moreover, the thin-film thermoelectric cooler can have multiple stages in which each stage contains a heat source plate, a heat sink plate, a p-type super-latticed thermoelectric element, and a n type super-latticed thermoelectric element. By bonding an output heat source plate on the thin-film thermoelectric cooler to an input heat sink plate on the bulk-material thermoelectric cooler, the integration of the thin-film thermoelectric with the bulk-material-based thermoelectric yields a cascade thermoelectric cooler wherein the bulk-material-based thermoelectric cooler cools to 160 K and the thin-film thermoelectric device cools to cryogenic temperatures between 70 and 120 K. Another level of thin-film super-lattice integration can achieve temperatures of 30 K. Alternatively, the integration of a high ZT thin-film superlattice thermoelectric cooler on a multi-staged bulk-material-based thermoelectric cooler can produce a higher performance non-cryogenic cooler.

Abstract translation: 设计用于冷却至30至120K的低温的级联热电冷却器将基于散装材料的热电冷却器的高性能\高ZT BixSb2-xTe3和Bi2Te3-xSe3基超晶格结构薄膜热电装置与基于散装材料的热电冷却器相结合 多个级联冷级，每个连续级联的冷级能够冷却到逐渐降低的温度。 散装材料热电冷却器中的每个冷阶段包括热源板，散热板，p型热电和n型热电。 此外，薄膜热电冷却器可以具有多级，其中每个级包含热源板，散热板，p型超网格热电元件和n型超网格热电元件。 通过将薄膜热电冷却器上的输出热源板结合到散装材料热电冷却器上的输入散热板，薄膜热电与体材料型热电体的集成产生级联热电冷却器，其中 基于散装材料的热电冷却器冷却至160K，薄膜热电装置冷却至70至120K之间的低温温度。另一个级别的薄膜超晶格集成可实现30K的温度。或者，集成 在多级基体材料型热电冷却器上的高ZT薄膜超晶格热电冷却器可以产生更高性能的非低温冷却器。

公开(公告)号：US20030126865A1

公开(公告)日：2003-07-10

申请号：US10237108

申请日：2002-09-09

Applicant: Research Triangle Institute

Inventor： Rama Venkatasubramanian

IPC: F25B021/02 ,  F25B007/00

CPC classification number: F25B21/02 ,  H01L35/16 ,  H01L35/325

Abstract: A cascade thermoelectric cooler designed to cool to cryogenic temperatures of 30 to 120 K. integrates high performancenullhigh-ZT BixSb2nullxTe3 and Bi2Te3nullxSe3 based super-lattice-structure thin-film thermoelectric devices with a bulk-material based thermoelectric cooler including plural cascaded cold stages with each successive cascaded cold stage able to cool to a progressively lower temperature. Each cold stage in the bulk-material thermoelectric cooler includes a heat source plate, a heat sink plate, a p-type thermoelectric, and a n-type thermoelectric. Moreover, the thin-film thermoelectric cooler can have multiple stages in which each stage contains a heat source plate, a heat sink plate, a p-type super-latticed thermoelectric element, and a n type super-latticed thermoelectric element. By bonding an output heat source plate on the thin-film thermoelectric cooler to an input heat sink plate on the bulk-material thermoelectric cooler, the integration of the thin-film thermoelectric with the bulk-material-based thermoelectric yields a cascade thermoelectric cooler wherein the bulk-material-based thermoelectric cooler cools to 160 K. and the thin-film thermoelectric device cools to cryogenic temperatures between 70 and 120 K. Another level of thin-film super-lattice integration can achieve temperatures of 30 K. Alternatively, the integration of a high ZT thin-film superlattice thermoelectric cooler on a multi-staged bulk-material-based thermoelectric cooler can produce a higher performance non-cryogenic cooler.

Abstract translation: 设计用于冷却至30至120K的低温的级联热电冷却器。集成了基于散装材料的热电冷却器的高性能\高ZT BixSb2-xTe3和Bi2Te3-xSe3基超晶格结构薄膜热电装置，其包括 多个级联冷级，每个连续级联的冷级能够冷却到逐渐降低的温度。 散装材料热电冷却器中的每个冷阶段包括热源板，散热板，p型热电和n型热电。 此外，薄膜热电冷却器可以具有多级，其中每个级包含热源板，散热板，p型超网格热电元件和n型超网格热电元件。 通过将薄膜热电冷却器上的输出热源板结合到散装材料热电冷却器上的输入散热板，薄膜热电与体材料型热电体的集成产生级联热电冷却器，其中 基于散料的热电冷却器冷却至160K，薄膜热电装置冷却至70至120K之间的低温温度。另一层次的薄膜超晶格集成可实现30K的温度。或者， 在多级基体材料型热电冷却器上集成高ZT薄膜超晶格热电冷却器可以产生更高性能的非低温冷却器。

公开(公告)号：US20020132828A1

公开(公告)日：2002-09-19

申请号：US09755021

申请日：2001-01-08

Applicant: Research Triangle Institute

Inventor： F. Ivy Carroll ,  James B. Thomas ,  S. Wayne Mascarella

IPC: A61K031/445

CPC classification number: C07D401/12

Abstract: Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors relative to nor-BNI, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.

Abstract translation: 提供了卡帕阿片受体拮抗剂，其相对于nor-BNI对κ阿片受体的功能结合测定产生显着改善，以及这些拮抗剂在治疗通过κ阿片样受体如海洛因或可卡因结合而改善的疾病状态的用途 成瘾

公开(公告)号：US20010052234A1

公开(公告)日：2001-12-20

申请号：US09812811

申请日：2001-03-21

Applicant: Research Triangle Institute

Inventor： Rama Venkatasubramanian

IPC: F25B021/02

CPC classification number: F25B21/02 ,  H01L35/16 ,  H01L35/325

Abstract: A cascade thermoelectric cooler designed to cool to cryogenic temperatures of 30 to 120 K integrates high performancenullhigh-ZT BixSb2nullxTe3 and Bi2Te3nullxSe3-based super-lattice-structure thin-film thermoelectric devices with a bulk-material based thermoelectric cooler including plural cascaded cold stages with each successive cascaded cold stage able to cool to a progressively lower temperature. Each cold stage in the bulk-material thermoelectric cooler includes a heat source plate, a heat sink plate, a p-type thermoelectric, and a n-type thermoelectric. Moreover, the thin-film thermoelectric cooler can have multiple stages in which each stage contains a heat source plate, a heat sink plate, a p-type super-latticed thermoelectric element, and a n type super-latticed thermoelectric element. By bonding an output heat source plate on the thin-film thermoelectric cooler to an input heat sink plate on the bulk-material thermoelectric cooler, the integration of the thin-film thermoelectric with the bulk-material-based thermoelectric yields a cascade thermoelectric cooler wherein the bulk-material-based thermoelectric cooler cools to 160 K and the thin-film thermoelectric device cools to cryogenic temperatures between 70 and 120 K. Another level of thin-film super-lattice integration can achieve temperatures of 30 K. Alternatively, the integration of a high ZT thin-film superlattice thermoelectric cooler on a multi-staged bulk-material-based thermoelectric cooler can produce a higher performance non-cryogenic cooler.

Abstract translation: 设计用于冷却至30至120K的低温的级联热电冷却器将基于散装材料的热电冷却器的高性能\高ZT BixSb2-xTe3和Bi2Te3-xSe3基超晶格结构薄膜热电装置与基于散装材料的热电冷却器相结合 多个级联冷级，每个连续级联的冷级能够冷却到逐渐降低的温度。 散装材料热电冷却器中的每个冷阶段包括热源板，散热板，p型热电和n型热电。 此外，薄膜热电冷却器可以具有多级，其中每个级包含热源板，散热板，p型超网格热电元件和n型超网格热电元件。 通过将薄膜热电冷却器上的输出热源板结合到散装材料热电冷却器上的输入散热板，薄膜热电与体材料型热电体的集成产生级联热电冷却器，其中 基于散装材料的热电冷却器冷却至160K，薄膜热电装置冷却至70至120K之间的低温温度。另一个级别的薄膜超晶格集成可实现30K的温度。或者，集成 在多级基体材料型热电冷却器上的高ZT薄膜超晶格热电冷却器可以产生更高性能的非低温冷却器。

公开(公告)号：US20240344956A1

公开(公告)日：2024-10-17

申请号：US18631969

申请日：2024-04-10

Applicant: Research Triangle Institute

Inventor： Anthony Clint Clayton ,  Ryan Chartier ,  Jameson Holden ,  Roger Pope

IPC: G01N15/075 ,  G01N15/06

CPC classification number: G01N15/075 ,  G01N15/0618

Abstract: A particle detector system for particle analysis. The system has a detection chamber for introduction of a fluid stream having particles, a light source configured to irradiate the particles across a two-dimensional plane in the detection chamber. and a light detector configured to detect either light scattered by particles or light emitted from the particles.

公开(公告)号：US12109549B2

公开(公告)日：2024-10-08

申请号：US17054590

申请日：2019-05-17

Applicant: Research Triangle Institute

Inventor： Ignacio Luz Minguez ,  Mustapha Soukri ,  Marty Lail ,  Lora Goon Toy

IPC: B01J20/22 ,  B01D53/02 ,  B01D53/22 ,  B01J20/28

CPC classification number: B01J20/226 ,  B01D53/02 ,  B01D53/228 ,  B01J20/28026 ,  B01J20/28033 ,  B01J20/28059 ,  B01J20/28061 ,  B01J20/28064 ,  B01J20/28066 ,  B01J20/28083 ,  B01D2253/204

Abstract: A method for making a metal organic framework suspension is described herein. The method includes providing a hybrid material comprising a nano-crystalline metal organic framework comprising micropores and a mesoporous polymeric material comprising mesopores, wherein the nano-crystalline metal organic framework is homogeneously dispersed and substantially present only within the mesopores or void spaces of the mesoporous polymeric material; and wherein the hybrid material has a weight percentage of the metal organic framework in the range of 5-50% relative to the total weight of the hybrid material. The method includes contacting the hybrid material with a solvent in which the mesoporous polymeric material is soluble, thereby forming a polymeric solution in which the nano-crystalline metal organic framework is substantially homogeneously dispersed and suspended.