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    Sealed containers and methods of making and filling same
    273.
    发明授权
    Sealed containers and methods of making and filling same 有权
    密封容器及其制造和填充方法

    公开(公告)号：US07100646B2

    公开(公告)日：2006-09-05

    申请号：US10655455

    申请日：2003-09-03

    Applicant: Daniel Py ,  Norbert M. Assion

    Inventor： Daniel Py ,  Norbert M. Assion

    IPC: B65B1/04

    CPC classification number: B65B3/003 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/1425 ,  A61J1/1431 ,  A61J1/1468 ,  A61J1/18 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/2096 ,  A61M2207/00 ,  A61M2209/045 ,  B65B3/027 ,  B65B7/161 ,  B65B51/10 ,  B65B55/08 ,  B65B2039/009 ,  B65D51/002

    Abstract: Disclosed is a uniquely configured medicament vial assembly which includes a storage vial, a stopper member and a securing ring. The vial assembly is configured to improve healthcare worker safety by providing a shielded gripping location to aid in the reduction of accidental needle sticks. The storage vial has a body portion which defines an interior chamber for storing a predetermined medicament and a neck portion through which medicament is received into and withdrawn from the interior chamber. The stopper member is inserted into the mouth of the vial and establishes a first seal. The securing ring is engaged with the mouth of the vial and adapted and configured for retaining the stopper member within the vial mouth and effectuating a second seal. The securing ring is formed from a thermoplastic and/or elastic material. Preferably, the securing ring is formed by molding the thermoplastic and/or elastic material over a portion of the storage vial and stopper member when engaged within the vial mouth.

    Abstract translation: 公开了一种独特构造的药物小瓶组件，其包括存储小瓶，止动构件和固定环。 小瓶组件被配置成通过提供屏蔽夹持位置来帮助减少意外的针棒来改善医护人员的安全性。 存储小瓶具有主体部分，其限定用于存储预定药物的内部腔室和颈部部分，药物通过所述颈部部分容纳到内部腔室中并从内部腔室中排出。 止动件插入小瓶的口中并建立第一密封。 固定环与小瓶的口接合并适于和构造成将止动件保持在小瓶口内并实现第二密封。 固定环由热塑性和/或弹性材料形成。 优选地，固定环通过在接合在小瓶口中时将热塑性和/或弹性材料模制在存储小瓶和止动构件的一部分上而形成。

    Container with valve assembly for filling and dispensing substances, and apparatus and method for filling
    274.
    发明授权
    Container with valve assembly for filling and dispensing substances, and apparatus and method for filling 有权
    具有用于填充和分配物质的阀组件的容器，以及用于填充的装置和方法

    公开(公告)号：US07077176B2

    公开(公告)日：2006-07-18

    申请号：US10833371

    申请日：2004-04-28

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65B1/04

    CPC classification number: B65B55/08 ,  A61J1/1425 ,  A61J1/1431 ,  A61J1/1468 ,  A61J1/1481 ,  A61J1/1487 ,  A61J1/18 ,  A61J1/2037 ,  A61J1/2041 ,  A61J1/2055 ,  A61J1/2096 ,  A61M2207/00 ,  B65B3/003 ,  B65D47/248

    Abstract: A vial has a body defining a chamber for receiving a substance therein; and a valve assembly coupled in fluid communication with the chamber and defining (i) an open position permitting at least one of (a) passage of the substance through the valve assembly and into the chamber for storing the substance in the chamber, and (b) passage of the substance out of the chamber for dispensing the substance therefrom; and (ii) a closed position forming a fluid-tight seal between the chamber and exterior of the container. A filling member engages a flexible valve member of the valve assembly to move the valve member between the closed and open positions to fill and seal the vial, respectively. A syringe is connectable to the vial. The valve assembly opens upon connecting the syringe to the vial to allow the substance within the vial to be withdrawn from the vial and into the syringe by actuating a plunger of the syringe, and the valve assembly closes upon disconnecting the vial and syringe to hermetically seal and store the substance remaining in the syringe for later use.

    Abstract translation: 小瓶具有限定用于在其中接收物质的室的主体; 以及阀组件，其与所述腔室流体连通地联接并且限定（i）允许所述物质通过所述阀组件并进入所述腔室中以将所述物质存储在所述腔室中的至少一个的打开位置，以及（b ）物质从室中通过以从其中分配物质; 和（ii）在容器和容器的外部之间形成流体密封的封闭位置。 填充构件接合阀组件的柔性阀构件以在闭合位置和打开位置之间移动阀构件以分别填充和密封小瓶。 注射器可连接到小瓶。 在将注射器连接到小瓶上时，阀组件打开，以通过致动注射器的柱塞来使小瓶中的物质从小瓶中取出并进入注射器，并且在将小瓶和注射器断开以气密密封时阀组件关闭 并将剩余的物质储存在注射器中以备后用。

    Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial
    277.
    发明授权
    Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial 有权
    具有可热封帽的药物小瓶，以及用于填充小瓶的装置和方法

    公开(公告)号：US07032631B2

    公开(公告)日：2006-04-25

    申请号：US10766172

    申请日：2004-01-28

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65B1/20

    CPC classification number: A61J1/18 ,  A61J1/1406 ,  A61J1/1468 ,  A61L2/08 ,  A61M2207/00 ,  B29C65/16 ,  B29C65/1616 ,  B29C65/1654 ,  B29C65/1677 ,  B29C65/18 ,  B29C66/001 ,  B29C66/1222 ,  B29C66/1224 ,  B29C66/12461 ,  B29C66/1312 ,  B29C66/342 ,  B29C66/534 ,  B29C66/5344 ,  B29C66/612 ,  B29C66/71 ,  B29C66/73755 ,  B29C66/7392 ,  B29C66/73921 ,  B29C66/7394 ,  B29C66/8322 ,  B29C67/004 ,  B29L2031/7158 ,  B29L2031/753 ,  B65B3/003 ,  B65B7/161 ,  B65D51/002 ,  B29C65/00 ,  B29K2025/08

    Abstract: A resealable cap (110, 210) for a medicament vial (114, 214) has a base portion (112, 212) formed of vulcanized rubber or like material known for providing a stable environment for the medicament contained within the vial, and a resealable portion (126, 226) overlying the base portion. The resealable portion (126, 226) is made of low-density polyethylene or like material, and can be punctured by a needle or like injection member (140, 282) for dispensing medicament into the vial (114, 214). Prior to filling, the cap (110, 210) is assembled to the vial (114, 214) and the cap/vial assembly is sterilized. Then, a needle (140, 282) is inserted through the cap (110, 210) and medicament is introduced through the needle and into the vial. Upon withdrawal of the needle (140, 282), the penetrated region of the cap (248) is fused by laser (276) or direct heat sealing (264) to hermetically seal the needle hole (294) in the cap.

    Abstract translation: 用于药物小瓶（114,214）的可重新密封的帽（110,210）具有由硫化橡胶或类似材料形成的基部（112,212），其已知用于为容纳在小瓶内的药物提供稳定的环境，并且可重新密封 覆盖基部的部分（126,226）。 可再密封部分（126,226）由低密度聚乙烯或类似材料制成，并且可以被针或类似的注射构件（140,282）刺穿，用于将药物分配到小瓶（114,214）中。 在填充之前，将帽（110,210）组装到小瓶（114,214）上，并且帽/瓶组件被灭菌。 然后，将针（140,282）插入穿过盖（110,210），药物通过针引入并进入小瓶。 在针（140,282）取出时，帽（248）的穿透区域通过激光（276）或直接热密封（264）熔合，以密封帽中的针孔（294）。

    Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances
    278.
    发明申请
    Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances 有权
    具有用于存储和分配计量的物质的单向阀的侧向致动的分配器

    公开(公告)号：US20060065677A1

    公开(公告)日：2006-03-30

    申请号：US11237599

    申请日：2005-09-27

    Applicant: Daniel Py ,  Julian Chan ,  David Fellows ,  Eric Hartman ,  Bing He

    Inventor： Daniel Py ,  Julian Chan ,  David Fellows ,  Eric Hartman ,  Bing He

    IPC: B67D5/40

    CPC classification number: B65D83/0094 ,  A45D34/04 ,  A45D2200/055 ,  A45D2200/056 ,  A61M35/003 ,  B05B11/00416 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3033 ,  B05B11/3094 ,  B65B1/04 ,  B65D83/0033 ,  G01F11/025 ,  G01F11/08

    Abstract: A dispenser for dispensing a substance, such as a pharmaceutical, ophthalmic, dermatological, cosmeceutical, cosmetic or other product, has a body defining a variable-volume storage chamber for storing the product. A dispensing portion of the dispenser is connected with the body and defines a bore coupled in fluid communication with the storage chamber for receiving substance therefrom, and an outlet aperture coupled in fluid communication with the bore. A one-way valve of the dispenser includes an axially-extending valve seat and an axially-extending flexible valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture to allow the passage of substance through the seam and out of the dispenser. The dispenser further comprises an actuator and piston assembly including a piston receivable within the bore, a manually-engageable actuator connected to the piston for moving the piston between first and second positions relative to the bore to dispense substance within the bore through the outlet aperture, and an integral, dome-shaped spring coupled to at least one of the piston and the actuator for biasing the piston in a direction from one of the first and second positions toward the other.

    Abstract translation: 用于分配物质（例如药物，眼科，皮肤病学，药妆，化妆品或其他产品）的分配器具有限定用于存储产品的可变容积储存室的主体。 分配器的分配部分与主体连接并且限定了与储存室流体连通以接收物质的孔以及与孔流体连通的出口孔。 分配器的单向阀包括轴向延伸的阀座和位于阀座上的轴向延伸的柔性阀盖，并且在其间限定一个常闭的轴向延伸的接缝，形成在阀盖之间的流体密封 和阀座。 柔性阀盖可相对于阀座移动，并且接缝可与出口孔流体连通以允许物质通过接缝并从分配器中通过。 分配器还包括致动器和活塞组件，其包括可接收在孔内的活塞，连接到活塞的可手动接合的致动器，用于相对于孔移动活塞在第一和第二位置之间，以通过出口孔分配孔内的物质， 以及联接到所述活塞和所述致动器中的至少一个的整体的圆顶形弹簧，用于沿从所述第一位置和所述第二位置之一向另一个方向偏压所述活塞。

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