公开(公告)号：US06960566B1

公开(公告)日：2005-11-01

申请号：US09831047

申请日：1999-11-05

Applicant: Magdalena Blaszczyk-Thurin

Inventor： Magdalena Blaszczyk-Thurin

IPC: A61K38/17 ,  A61K38/00 ,  C07K5/00

CPC classification number: A61K38/12 ,  A61K38/10

Abstract: Compositions containing one or more peptido-mimetics or modified peptido-mimetics of a carbohydrate ligand of an adhesion molecule in a physiologically acceptable carrier are useful for methods of reducing metastasis in a mammal and for inhibiting inflammatory response in a mammal. Particularly useful are embodiments in which the ligand is a Lewis antigen and/or the adhesion molecule is a selectin, e.g, E-selectin. Methods are disclosed for identifying peptido-mimetics of carbohydrate ligands, which may be involved in binding of tumor cells to other cells, such as endothelial cells.

Abstract translation: 在生理上可接受的载体中含有粘附分子的碳水化合物配体的一个或多个肽基 - 模拟物或修饰的肽模拟物的组合物可用于减少哺乳动物转移和抑制哺乳动物炎症反应的方法。 特别有用的是其中配体是路易斯抗原和/或粘附分子是选择蛋白的实施方案，例如E-选择蛋白。 公开了用于鉴定碳水化合物配体的肽模拟物的方法，其可参与肿瘤细胞与其它细胞如内皮细胞的结合。

公开(公告)号：US06929718B2

公开(公告)日：2005-08-16

申请号：US10607397

申请日：2003-06-26

Applicant: Keiichi Kimura

Inventor： Keiichi Kimura

IPC: D21F7/08 ,  D21F3/02 ,  D21F3/04

CPC classification number: D21F3/0227 ,  Y10S162/901 ,  Y10T428/2457

Abstract: In a shoe press belt of a papermaking machine, the part of the paper web-facing layer in which water-holding grooves are formed is composed of a surface sublayer, having a relatively low hardness, and an underlying layer having a relatively high hardness. The higher hardness of the underlying layer prevents cracks from forming where the cross-sectional shape of the grooves tends to change as the belt is compressed. The lower hardness of the surface sublayer prevents the formation of cracks as a result of forces acting on the belt in the direction opposite to the machine direction at the nip location in a papermaking machine.

Abstract translation: 在造纸机的靴式压榨带中，形成有保水沟的纸幅面向层的部分由具有较低硬度的表面子层和具有较高硬度的下层构成。 下层的较高硬度防止了当带被压缩时凹槽的横截面形状趋于变化的裂纹形成。 表面亚层的较低的硬度防止由于在造纸机器中的压区位置处沿与机器方向相反的方向作用在带上的力而形成裂缝。

公开(公告)号：US06910434B2

公开(公告)日：2005-06-28

申请号：US10362679

申请日：2001-08-30

Applicant: Edwin Lundgren

Inventor： Edwin Lundgren

IPC: B63B1/12 ,  B63H9/06 ,  B63H9/04

CPC classification number: B63H9/06 ,  B63B1/121 ,  B63H9/0685 ,  B63H2025/066

Abstract: A control device for a steering kite on a boat. The steering kite can be steered by a steering device and at least two or three, preferably at least four or five, suspension lines. The control device comprises at least one force introduction rail that extends horizontally over the water line and on which a deviation device for the suspension lines is positioned in such a way that it can move back and forth. The rail is fixed to the boat between the steering kite and the steering device in such a way that the traction force of the steering kite produces torque about the longitudinal axis and/or the transverse axis of the boat in the water, by means of which the leeward side of the boat is lifted upwards.

Abstract translation: 船上的风筝控制装置。 转向风筝可以通过转向装置和至少两个或三个，优选至少四个或五个悬挂线来转向。 控制装置包括至少一个在水线上水平延伸的力导入轨道，并且用于悬挂线路的偏移装置可以以这样的方式前后移动。 轨道固定在转向风筝和转向装置之间的船上，使得转向风筝的牵引力围绕船的纵向轴线和/或横向轴线产生扭矩，借助于此 船的背风侧向上抬起。

公开(公告)号：US06905597B2

公开(公告)日：2005-06-14

申请号：US10296597

申请日：2001-05-23

Applicant: Helga Garbaty ,  Stefan Garbaty ,  Thomas Garbaty ,  Harriet Garbaty

Inventor： Rudolf Franz Garbaty

IPC: B01D17/02 ,  E02B15/04 ,  E02B15/10

CPC classification number: E02B15/048 ,  B01D17/0214 ,  E02B15/106 ,  Y02A20/204 ,  Y10S210/923

Abstract: A device for recovering oil from an oil-slick on a stretch of water is supported on the water by at least one first floating body and is provided with an inlet that is open facing the oil-slick and that flows into a channel with side walls. The channel is provided with at least one separating body that extends between the side walls in such a manner that an upper drain zone is formed above the separating body and a separate lower drain zone is formed below the separating body. The front edge of the separating body facing the oil-slick is substantially disposed on the level of the water/oil interface and the oil can be discharged from the upper drain zone. The device makes use of the natural interface between the oil-slick and the subjacent water.

Abstract translation: 一种用于从一段水面上的润滑油回收油的装置由至少一个第一浮体支撑在水面上，并且设置有一个面向油浮的开口并流入具有侧壁的通道的入口 。 通道设置有至少一个在侧壁之间延伸的分离体，使得在分离体上方形成上排水区，在分离体的下方形成分开的下排水区。 面对油滑的分离体的前边缘基本上设置在水/油界面的高度上，并且油可以从上排水区排出。 该装置利用油浮液和下层水之间的自然界面。

公开(公告)号：US06888688B2

公开(公告)日：2005-05-03

申请号：US10276951

申请日：2001-05-10

Applicant: Jeffrey Peter Wright ,  David Paul Steven

Inventor： Jeffrey Peter Wright ,  David Paul Steven

IPC: H01L27/32 ,  G02B27/02

CPC classification number: H01L51/5275 ,  H01L27/3244

Abstract: An optoelectronic display device comprises an organic light emitting diode microdisplay 1 and a viewing convex lens 2 arranged at a distance from the microdisplay which may be less than, equal to or greater than the focal length of the lens.

Abstract translation: 光电子显示装置包括有机发光二极管微型显示器1和布置在与微型显示器相距一定距离处的观察凸透镜2，其可以小于，等于或大于透镜的焦距。

公开(公告)号：US06887463B2

公开(公告)日：2005-05-03

申请号：US10167264

申请日：2002-06-10

Applicant: James M. Wilson ,  Karen Kozarsky ,  Jerome Strauss, III

Inventor： James M. Wilson ,  Karen Kozarsky ,  Jerome Strauss, III

IPC: C12N15/09 ,  A61K35/76 ,  A61K38/00 ,  A61K38/17 ,  A61K48/00 ,  A61P3/06 ,  C07K14/705 ,  C12N5/10 ,  C12N7/00 ,  C12N15/12 ,  C12N15/861 ,  C12N15/86 ,  C12N15/864

CPC classification number: C12N15/86 ,  A61K38/00 ,  A61K48/00 ,  C07K14/705 ,  C12N2710/10344 ,  C12N2799/022

Abstract: The invention provides a recombinant viral vector comprising the DNA of, or corresponding to, at least a portion of the genome of an adenovirus, which portion is capable of infecting a hepatic cell; and a human VLDL receptor gene operatively linked to regulatory sequences directing its expression. The vector is capable of expressing the normal VLDL receptor gene product in hepatic cells in vivo or in vitro. This viral vector is useful in the treatment of metabolic disorders caused by the accumulation of LDL in plasma, such as familial hypercholesterolemia or familial combined hyperlipidemia.

Abstract translation: 本发明提供了一种重组病毒载体，其包含腺病毒基因组的至少一部分的DNA或相当于该部分能够感染肝细胞的DNA; 和与指导其表达的调节序列可操作地连接的人类VLDL受体基因。 该载体能够在体内或体外在肝细胞中表达正常的VLDL受体基因产物。 该病毒载体可用于治疗血浆中LDL积累引起的代谢紊乱，如家族性高胆固醇血症或家族性高脂血症。

公开(公告)号：US06875141B2

公开(公告)日：2005-04-05

申请号：US10388004

申请日：2003-03-13

Applicant: Tatsuya Konishi ,  Toyonaga Saitoh ,  Yoshio Kurokawa ,  Tsutomu Namie

Inventor： Tatsuya Konishi ,  Toyonaga Saitoh ,  Yoshio Kurokawa ,  Tsutomu Namie

IPC: F02B67/06 ,  F16H7/08 ,  F16H7/22

CPC classification number: F16H7/0836 ,  F16H2007/0806 ,  F16H2007/0812 ,  F16H2007/0853 ,  F16H2007/0859

Abstract: In a ratchet-type hydraulic tensioner for use with a timing chain of an internal combustion engine, two or more oil reservoirs gradually receive oil fed under pressure from an external source, and supply the oil through a hydraulic valve mechanism to a high pressure oil chamber formed by a plunger and a housing in which the plunger is slidable. Throttle holes, formed in partition walls separating the reservoirs, control the flow of oil from one reservoir to another. An excess oil discharge hole is optionally provided in one of the reservoirs. The invention prevents abnormal protrusion of the plunger, reduces chain noise and component damage due to wear, and rapidly re-establishes proper tension on engine start-up.

Abstract translation: 在与内燃机的正时链一起使用的棘轮型液压张紧器中，两个以上的储油器逐渐接收来自外部源的加压供油，并通过液压阀机构将油供给到高压油室 由柱塞和壳体形成，其中柱塞可滑动。 在分隔储存器的分隔壁中形成的节流孔控制油从一个储存器到另一个储存器的流动。 在其中一个储存器中可选地设置多余的排油孔。 本发明防止柱塞的异常突出，减少由于磨损引起的链条噪音和部件损坏，并且在发动机起动时快速重新建立适当的张力。

公开(公告)号：US06870147B1

公开(公告)日：2005-03-22

申请号：US10363271

申请日：2002-05-20

Applicant: Hiroshi Tsukuda

Inventor： Hiroshi Tsukuda

IPC: G01N17/00 ,  G01J1/36

CPC classification number: G01N21/255 ,  G01N17/004 ,  G01N21/33

Abstract: A light stability testing device for conducting an accurate light stability test that permits an accurate ultraviolet irradiation and an accurate visible light irradiation, the device comprising an optical sensor having a visible light measuring sensor (5) for measuring the dose of visible light, and a ultraviolet measuring sensor (6) for measuring the dose of ultraviolet ray, an optical system having a total light regulating means (331) for regulating the absolute quantity of light emitted from a light source and a ultraviolet ray regulating means (335) for regulating the dose of ultraviolet ray in light regulated by the total light regulating means, and a control unit for controlling a total light control unit that controls the total light regulating means (331) by a signal from a visible light measuring sensor (5), and the ultraviolet ray regulating means (335) by a signal from the ultraviolet measuring sensor (6).

Abstract translation: 一种光稳定性测试装置，用于进行精确的光稳定性测试，其允许精确的紫外线照射和精确的可见光照射，所述装置包括具有用于测量可见光的剂量的可见光测量传感器（5）的光学传感器，以及 用于测量紫外线剂量的紫外线测量传感器（6），具有用于调节从光源发射的光的绝对量的总光调节装置（331）的光学系统和用于调节光源的紫外线调节装置（335） 由总光调节装置调节的光的紫外线剂量;以及控制单元，用于控制通过来自可见光测量传感器（5）的信号控制总光调节装置（331）的总光控制单元，以及 通过来自紫外线测量传感器（6）的信号的紫外线调节装置（335）。

公开(公告)号：US06869979B1

公开(公告)日：2005-03-22

申请号：US10259683

申请日：2002-09-27

Applicant: John W. Rich, Jr.

Inventor： John W. Rich, Jr.

IPC: C07C27/00 ,  C10G2/00 ,  C10K1/00 ,  C10K1/20

CPC classification number: C10G2/32 ,  C10K1/00 ,  C10K1/20

Abstract: The effective coupling and combination of coal gasification and coal liquefaction techniques to produce ultra clean liquid fuels from carbonaceous matter preferably provided from an abundance of waste coal mining material. The method and apparatus includes a final sulfur washing step utilizing a zinc oxide membrane to remove virtually all sulfur from synthetic gas produced in an entrained flow gasifier before the synthetic gas is permitted to enter a slurry phase vessel having a catalyst used to produce a parafin from which liquid fuel is produced. The liquid fuel is preferably an ultra clean, high cetane, sulfur-free diesel fuel.

Abstract translation: 煤气化和煤液化技术的有效耦合和组合，从碳质物质生产超清洁液体燃料，优选由大量的废煤开采材料提供。 该方法和设备包括最终的硫清洗步骤，其中使用氧化锌膜从合成气体中产生的合成气体中几乎所有的硫除去，在合成气体被允许进入具有用于产生巴拉明的催化剂的淤浆相容器之前， 生产哪种液体燃料。 液体燃料优选为超洁净，高十六烷，无硫柴油。

公开(公告)号：US06861030B2

公开(公告)日：2005-03-01

申请号：US10182764

申请日：2001-06-29

Applicant: Yuichiro Shindo

Inventor： Yuichiro Shindo

IPC: B22F9/02 ,  C22B9/22 ,  C22B34/14 ,  C22C1/04 ,  C22C16/00 ,  C22C27/00 ,  C23C14/34 ,  H01L21/28 ,  H01L23/532 ,  H01L29/51 ,  C22L27/00

CPC classification number: H01L21/28194 ,  B22F9/023 ,  C22B9/228 ,  C22B34/14 ,  C22C1/0458 ,  C22C16/00 ,  C22C27/00 ,  C23C14/3414 ,  H01L23/53257 ,  H01L29/51 ,  H01L29/517 ,  H01L2924/0002 ,  H01L2924/00

Abstract: The present invention relates to high-purity zirconium or hafnium with minimal impurities, particularly where the content of alkali metal elements such as Na, K; radioactive elements such as U, Th; transitional metals or heavy metals or high melting point metal elements such as Fe, Ni, Co, Cr, Cu, Mo, Ta, V; and gas components such as C, O, etc. is extremely reduced, as well as to an inexpensive manufacturing method of such high-purity zirconium or hafnium, thereby reducing the impurities hindering the guarantee of the operational performance of semiconductors. The present invention further relates to an inexpensive and safe manufacturing method of high-purity zirconium or hafnium powder from hydrogenated high-purity zirconium or hafnium powder.

Abstract translation: 本发明涉及具有最小杂质的高纯度锆或铪，特别是碱金属元素如Na，K的含量; 放射性元素如U，Th; 过渡金属或重金属或高熔点金属元素如Fe，Ni，Co，Cr，Cu，Mo，Ta，V; 并且气体成分例如C，O等被极大地降低，并且成为这种高纯度锆或铪的廉价的制造方法，从而减少妨碍半导体操作性能的保证的杂质。 本发明还涉及从氢化的高纯度锆或铪粉末制成的高纯度锆或铪粉末的廉价且安全的制造方法。