公开(公告)号：US09757027B2

公开(公告)日：2017-09-12

申请号：US15227839

申请日：2016-08-03

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/14 ,  A61B3/10 ,  G01B9/02 ,  G01B11/06 ,  A61B3/00 ,  A61B3/15 ,  G01N21/27 ,  G02B3/08

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: A system and method are described for performing tear film structure measurement. A broadband light source illuminates the tear film. A spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera performs large field of view imaging of the tear film, so as to obtain color information for all points of the tear film imaged by the color camera. A processing unit calibrates the camera at the point measured by the spectrometer so that the color obtained by the camera at the point matches the color of the spectrometer at the same point. The processing unit determines, from the color of respective points of the calibrated camera, thicknesses of one or more layers of the tear film at the respective points. Other applications are also described.

公开(公告)号：US20170074644A1

公开(公告)日：2017-03-16

申请号：US15311280

申请日：2015-05-14

Applicant: ADOM, Advanced Optical Technologies Ltd.

Inventor： Yoel Arieli ,  Yoel Cohen

IPC: G01B11/25 ,  H04N5/225 ,  G01N21/47

CPC classification number: G01B11/25 ,  G01B2210/50 ,  G01N21/39 ,  G01N21/4795 ,  G01N2021/1787 ,  H04N5/2254 ,  H04N5/2256

Abstract: A system (10) for analyzing an object (11) includes a light source (12) producing multiple light components, each of different wavelength and a respective amplitude, phase and polarization. An optical element (13) directs the light components on to the object to create known 2D patterns at different image planes displaced from the optical element by distances that are known functions of the wavelength of the light component. A 2D imager (20) images the 2D patterns and produces a plurality of full view 2D wavelength dependent patterns each corresponding to a known distance from the optical element and each having variable image contrast dependent on displacement of a surface of the object from the image plane, maximal image contrast being achieved when the surface of the object and image plane are coincident. A processing unit (25) determines the object surface based on the variable image contrast of each image.

Abstract translation: 用于分析物体（11）的系统（10）包括产生多个光分量的光源（12），每个光分量具有不同的波长和相应的振幅，相位和极化。 光学元件（13）将光分量引导到物体上，以在与光学元件偏移的不同图像平面上产生已知的2D图案，该距离是光分量的波长的已知功能。 2D成像器（20）对2D图案进行成像，并且产生多个全视图2D波长相关图案，每个图案对应于从光学元件的已知距离，并且每个具有可变图像对比度，取决于物体表面与图像平面的位移 当物体和图像平面的表面一致时，实现最大图像对比度。 处理单元（25）基于每个图像的可变图像对比度确定对象表面。

公开(公告)号：US20170038191A1

公开(公告)日：2017-02-09

申请号：US15304816

申请日：2015-04-29

Applicant: Adom, Advanced Optical Technologies Ltd.

Inventor： Yoel Arieli ,  Yoel Cohen

IPC: G01B9/02

CPC classification number: G01B9/02047 ,  G01B9/0209 ,  G01B9/02091

Abstract: A method for high dynamic range and high accuracy interferometry measurements is described. The method uses a broadband light source for generating light, an interferometer, a phase shifting device, an imaging optical system and a detector array for collecting and measuring the reflected light from an object. The detected light is processed by a processor unit to obtain the object's surface.

Abstract translation: 描述了用于高动态范围和高精度干涉测量的方法。 该方法使用用于产生光的宽带光源，干涉仪，相移装置，成像光学系统和用于收集和测量来自物体的反射光的检测器阵列。 检测到的光被处理器单元处理以获得物体的表面。

公开(公告)号：US20160338585A1

公开(公告)日：2016-11-24

申请号：US15227839

申请日：2016-08-03

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/10 ,  G01N21/27 ,  A61B3/00 ,  A61B3/15 ,  G02B3/08 ,  G01B11/06 ,  G01B9/02

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: A system and method are described for performing tear film structure measurement. A broadband light source illuminates the tear film. A spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera performs large field of view imaging of the tear film, so as to obtain color information for all points of the tear film imaged by the color camera. A processing unit calibrates the camera at the point measured by the spectrometer so that the color obtained by the camera at the point matches the color of the spectrometer at the same point. The processing unit determines, from the color of respective points of the calibrated camera, thicknesses of one or more layers of the tear film at the respective points. Other applications are also described.

Abstract translation: 描述了进行泪膜结构测量的系统和方法。 宽带光源照亮泪膜。 光谱仪测量来自泪膜的至少一个点的反射光的各个光谱。 彩色照相机对泪膜进行大视野成像，以获得由彩色照相机成像的泪膜的所有点的颜色信息。 处理单元在由光谱仪测量的点处校准相机，使得在该点处由相机获得的颜色与同一点处的光谱仪的颜色匹配。 处理单元根据校准的相机的各个点的颜色确定各个点处的泪膜的一层或多层的厚度。 还描述了其它应用。

公开(公告)号：US12213733B2

公开(公告)日：2025-02-04

申请号：US17921438

申请日：2021-04-25

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel Cohen ,  Ra'anan Gefen ,  Yoel Arieli ,  Lee Barnea Nehoshtan ,  Naor Deri

IPC: A61B3/10 ,  A61B3/00

Abstract: Systems and methods for detecting physical characteristics of a multilayered tissue of a subject, such as a tear film including analyzing received detector-output indicative of optical properties of light reflected or deflected from the respective multilayered tissue, to determine spectral properties of the multilayered tissue; and determining physical characteristics of the multilayered tissue by using multiple spectral models of the of the multilayered tissue, each model being associated with spectral properties indicative of different tissue characteristics, wherein physical characteristics of the multilayered tissue are determined by hierarchal determination of a best-fit model from the multiple spectral models.

公开(公告)号：US12023099B2

公开(公告)日：2024-07-02

申请号：US17473839

申请日：2021-09-13

Applicant: AdOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/15 ,  G01B9/02 ,  G01B11/06 ,  G01J3/02 ,  G01J3/45 ,  G01J3/453

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02044 ,  G01B11/0625 ,  G01B11/0675 ,  G01J3/0248 ,  G01J3/45 ,  G01J3/453 ,  G01J3/0229

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

公开(公告)号：US20220034716A1

公开(公告)日：2022-02-03

申请号：US17276265

申请日：2019-07-04

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel COHEN ,  Ra'anan GEFEN ,  Shlomi EPSTEIN ,  Yoel ARIELI

IPC: G01J3/02 ,  A61B3/107 ,  A61B3/00 ,  G01J3/45

Abstract: Apparatus and methods are described for calibrating an optical system that is used for measuring optical properties of a portion of a subjects body. During a calibration stage, a front surface of a calibration object (300) is illuminated, light reflected from a plurality of points on the calibration object (300) is detected, and intensities of the light reflected from the plurality of points on the calibration object (300) are measured. During a measurement stage, the portion of the subjects body is illuminated, and light reflected from the portion of the subjects body is detected. Measurements performed upon the light that was reflected from the portion of the subjects body are calibrated, using the measured intensities of the light reflected from the plurality of points on the calibration object (300). Other applications are also described.

公开(公告)号：US11116394B2

公开(公告)日：2021-09-14

申请号：US16322083

申请日：2017-08-02

Applicant: AdOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/14 ,  A61B3/10 ,  A61B3/00 ,  G01J3/45 ,  G01B11/06 ,  G01B9/02 ,  A61B3/15 ,  G01J3/02 ,  G01J3/453

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

公开(公告)号：US10456029B2

公开(公告)日：2019-10-29

申请号：US15802829

申请日：2017-11-03

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/14 ,  A61B3/10 ,  G01B9/02 ,  G01B11/06 ,  A61B3/00 ,  A61B3/15 ,  G01N21/27 ,  G02B3/08 ,  G01J3/00

Abstract: Apparatus and methods are described, for detecting the surface topography of a portion of a curved surface of an object. A beam of light is directed toward the surface from a broad angle of incidence with respect to an optical axis of a camera. Light reflected from the surface is received by the camera, via a narrow-angle aperture. One or more darkened regions in the received light are detected, and the surface topography of portion of the surface is detected at least partially in response to the detected darkened regions. Other applications are also described.

公开(公告)号：US10415954B2

公开(公告)日：2019-09-17

申请号：US16037680

申请日：2018-07-17

Applicant: Adom, Advanced Optical Technologies Ltd.

Inventor： Yoel Arieli ,  Yoel Cohen

IPC: G01B9/02

Abstract: Apparatus and methods are described for determining tomographic and/or topographic data relating to an object. The object is illuminated with at least one wave packet from light generated by a multi-spectral light source. The wave packet is split into two split wave packets, and an optical path difference (OPD) is introduced between the two split wave packets, that is smaller than the coherence length of the wave packet. The two split wave packets are combined to generate a 2D image of the illuminated object, and the data relating to the object is determined by processing the 2D image using long coherence phase shift interferometry algorithms, by analyzing the 2D image as if the 2D image was generated using monochromatic light having a wavelength that is equal to a mean wavelength of the wave packet. Other applications are also described.