摘要:
There is disclosed a method and apparatus for harvesting tissue using a cannula having a diameter of from 0.5 to 4.0 mm and of a length of from 25 to 20 cm to access by minimally invasive techniques a host to withdraw autogenous tissue processed to remove loose fat and/or fragmented tissue. Thereafter, the resulting tissue substrate is morcellated to form particulate tissue of a particle size of from 1 to 200 .mu.m. The particulate material is thence passed through screens having opening sizes of from 1 to 100 .mu.m to form a material of a size for introduction into a syringe of from 16 to 30 gauge for implantation in the host. The processed tissue may be admixed with extenders, gelling agents and the like.
摘要:
Embodiments isolate exposed surfaces to increase the effectiveness of different treatment modalities. Embodiments isolate hollow spaces within the body to increase the effectiveness of ultrasound energy and/or other treatments. Such hollow spaces within the body may include nasal surfaces, and recessed or sequestered surfaces, e.g. sinus cavity surfaces or other anatomical structures, such as upper and lower gastrointestinal tract, airways, uterine and vaginal cavities and the anorectal canal, for example. Isolating the area to be treated reduces the volume of the enclosed and delimited space and reduces the tissue surface against which the ultrasound and/or biologically active substances act. For example, isolating a hollow passageway within the body enhances the effectiveness of ultrasound within the isolated space, and constrains the biologically active fluid and/or the gel or fluid configured to conducts the ultrasonic energy from the emitter thereof (e.g., an ultrasound waveguide) to the surfaces to be treated.
摘要:
A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要:
A method of marking a cavity in a breast for subsequent visualization may include steps of providing a device having a delivery opening, a first marker and a second marker, the first and second markers being movable through the delivery opening, the first marker being configured to be visualized by ultrasound and the second marker configured to be radiopaque, the first and second markers being free to move relative to one another; introducing the device into a breast so that the delivery opening is positioned in a cavity formed in the breast; and moving the first marker and the second marker through the delivery opening and into the cavity in the breast, the first and second markers being free to move relative to one another when delivered into the cavity so that the first and second markers may take a number of different positions relative to one another when positioned within the cavity.
摘要:
A method of treating a cavity created by a percutaneous excisional procedure carried out through an incision includes steps of providing a post-procedure cavity implant, the post-procedure cavity implant including: a radiopaque element; a core portion coupled to the radiopaque element, the core portion including a first porous matrix defining a first controlled pore architecture, and a shell portion coupled to the core portion, the shell portion including a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture; implanting the post-procedure cavity implant into the cavity, and closing the incision.
摘要:
A device for cutting and collecting a specimen from a mass of tissue may include a shaft, an integrated cut and collect assembly coupled to the shaft and an actuator. The shaft may define an opening and may include an outer surface that defines a trough adjacent the opening, the trough defining a ledge portion that is cut out of the shaft. The integrated cut and collect assembly may include an RF cutting portion and a collection portion that includes a flexible membrane, the collection portion being attached to the cutting portion, the integrated cut and collect assembly being configured to assume a retracted position at least partially within the opening such that part of the collection portion is disposed within the trough and in contact with the ledge portion and a selectable expanded position that extends through the opening and away from the shaft. The cutting portion may be configured to cut the specimen from the mass of tissue and the collection portion may be configured to collect the cut specimen and to isolate the cut specimen within the membrane. The trough may be configured to minimize contact of the cutting portion with the tissue to be cut as the cutting portion is becoming fully energized in the retracted position. The actuator may be coupled to the integrated assembly such that operation of the actuator causes a deployment of the integrated assembly from the retracted position to the selectable expanded position.
摘要:
Devices and methods for collecting or cutting and collecting a specimen from a mass of tissue within a patient. The device may include a specimen collection assembly including a flexible membrane that isolates collected specimen from the surrounding tissue. The collection device may also include structures that draw the collected specimen toward the shaft and/or otherwise ease the insertion and retraction of the device and the collected specimen from the patient through a small incision.
摘要:
Devices and methods for cutting and collecting a specimen from a mass of tissue. The device may include an integrated cut and collect assembly. The integrated cut and collect assembly includes a cutting portion and a collection portion that includes a flexible membrane. The collection portion of the assembly is attached to the cutting portion thereof. The cutting portion is configured to cut the specimen from the mass of tissue and the collection portion is configured to collect the cut specimen and to encapsulate and isolate the cut specimen within the membrane to enable its safe retraction from the mass of tissue.
摘要:
An excisional biopsy system includes a tubular member that has a proximal end and a distal end in which one or more windows are defined. A first removable probe has a proximal portion that includes a cutting tool extender and a distal portion that includes a cutting tool. The first removable probe may be configured to fit at least partially within the tubular member to enable the cutting tool to selectively bow out of and to retract within one of the windows when the cutting tool extender is activated. A second removable probe has a proximal section that includes a tissue collection device extender and a distal section that includes a tissue collection device. The second removable probe may also be configured to fit at least partially within the tubular member to enable the tissue collection device to extend out of and to retract within one of the windows when the tissue collection device extender is activated. A third removable probe may also be provided. The third removable probe may also be configured to fit at least partially within the tubular member and may include an imaging device, such as an ultrasound transducer, mounted therein. By selectively activating the cutting tool and the tissue collection device while rotating the excisional device, a tissue specimen may be cut from the surrounding tissue and collected for later analysis.
摘要:
There is provided a device and a method for irradiating vascular tissues. The device generally includes a transfer device having a first chamber and a second chamber and a piston slidably disposed between the chambers. A balloon catheter is provided for positioning within the vascular system and is connected to the transfer device such that an inflation lumen of the balloon catheter is in fluid communication with the second chamber. A proximal end of the balloon catheter is affixed to a mounting block which is configured to receive the transfer device. An inflation device is provided to force fluid into the first chamber such that the piston is driven to force a radioactive fluid contained in the second chamber into the balloon.