Targeted Lung Denervation with Directionally-Adjustable Perfusion

    公开(公告)号:US20220287767A1

    公开(公告)日:2022-09-15

    申请号:US17658947

    申请日:2022-04-12

    IPC分类号: A61B18/14 A61B18/12

    摘要: A lung denervation method comprises advancing a catheter along the airway; deploying an open loop in contact with the epithelium; simultaneously delivering radio frequency energy from a plurality of discrete spaced-apart locations along the loop to target regions according to a set of ablation parameters sufficient to heat and interrupt nerve functionality; and forming a liquid film between the loop and the epithelium for minimizing collateral damage. The method serves to destroy motor axons of the peripheral bronchial nerve, blocks parasympathetic transmission in the pulmonary and reduces acetylcholine release, reducing airway smooth muscle tension and mucus production. Related systems are described.

    LUNG TUMOR ABLATION METHOD
    25.
    发明申请

    公开(公告)号:US20220241001A1

    公开(公告)日:2022-08-04

    申请号:US17658941

    申请日:2022-04-12

    IPC分类号: A61B18/12

    摘要: A lung tumor ablation method includes deploying a plurality of sensors in the tumor margin and monitoring ablation progress based on information from the sensors. An ablation electrode is inserted into a central region of the tumor and the site is irrigated. Power and irrigation flowrate are controlled to optimize ablation based on information from the sensors. Related apparatus and systems are described.

    LEARNING-BASED SPINE VERTEBRA LOCALIZATION AND SEGMENTATION IN 3D CT

    公开(公告)号:US20180286050A1

    公开(公告)日:2018-10-04

    申请号:US15763797

    申请日:2016-10-25

    IPC分类号: G06T7/11 G06T7/143

    摘要: Described herein is a novel method and system for segmentation of the spine using 3D volumetric data. In embodiments, a method includes an extracting step, localization step, and segmentation step. The extracting step comprises detecting the spine centerline and the spine canal centerline. The localization step comprises localizing the vertebra and intervertebral disc centers. Background and foreground constraints are created for each vertebra digit. Segmentation is performed for each vertebra digit and based on the hard constraints.