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公开(公告)号:US20220325313A1
公开(公告)日:2022-10-13
申请号:US17712452
申请日:2022-04-04
申请人: Conagen Inc.
发明人: Yisheng Wu , Wanli Lu , Jacob Thomas Courtney , David Nunn , Oliver Yu
摘要: Provided herein are recombinant nucleic acid molecules, nucleic acid constructs, fusion enzymes, transformed host cells, and methods for making aroma compounds alpha-ionone or beta-ionone.
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公开(公告)号:US20220205007A1
公开(公告)日:2022-06-30
申请号:US17570544
申请日:2022-01-07
申请人: Conagen Inc.
发明人: Guohong Mao , Michael Batten , Xiaodan Yu
摘要: The present invention relates, at least in part, to the production of steviol glycoside rebaudioside I through the use of variant UGT enzymes having activity to transfer a glucosyl group from UDP-glucose to rebaudioside A to produce rebaudioside I.
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公开(公告)号:US20220112525A1
公开(公告)日:2022-04-14
申请号:US17514043
申请日:2021-10-29
申请人: Conagen Inc.
发明人: Rui Zhou , Junying Ma , Oliver Yu
IPC分类号: C12P7/24 , C11B9/00 , A23L33/105 , C12N9/02
摘要: The present invention relates to the production of vanillin via the bioconversion of isoeugenol. The bioconversion can be mediated in a cellular system (e.g., an Escherichia coli bacterium), or in an enzymatic reaction mixture without a cellular system.
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公开(公告)号:US20210261991A1
公开(公告)日:2021-08-26
申请号:US17150774
申请日:2021-01-15
申请人: Conagen Inc.
摘要: Provided herein are methods for making gamma lactones comprising reacting a carboxylic acid substrate with a heterologous cytochrome P450 (CYP450) protein with carboxylic acid 4-hydroxylase activity.
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公开(公告)号:US10975403B2
公开(公告)日:2021-04-13
申请号:US16032800
申请日:2018-07-11
申请人: Conagen Inc.
发明人: Rui Zhou , Xiaodan Yu , Steven Chen
IPC分类号: C12N15/70 , C12N15/54 , C12N9/06 , C12N9/24 , C12P17/06 , A61K8/99 , A61K8/49 , A23L27/00 , A23L27/30 , A23L33/10 , A61Q19/00 , C07D311/32 , C12N15/81 , A61Q5/00
摘要: The present invention relates to the production of eriodictyol via bioconversion.
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公开(公告)号:US10752928B2
公开(公告)日:2020-08-25
申请号:US15566244
申请日:2016-04-14
申请人: Conagen Inc.
发明人: Guohong Mao , Jacob Edward Vick , Shi-Yan Li , Xiaodan Yu
摘要: Disclosed are whole-cell catalysts, methods of making the whole-cell catalysts, and methods of using the whole-cell catalysts to produce steviol glycosides.
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公开(公告)号:US10724062B2
公开(公告)日:2020-07-28
申请号:US16382280
申请日:2019-04-12
申请人: Conagen Inc.
发明人: Guohong Mao , Jacob Edward Vick , Michael Batten , David Byun , Yang Luo , Yilin Wu , Beihua Zhang , Xiaodan Yu
摘要: The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
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公开(公告)号:US20200002742A1
公开(公告)日:2020-01-02
申请号:US16506892
申请日:2019-07-09
申请人: Conagen Inc.
发明人: Guohong Mao , Michael Batten , Phillip Hunt , Xiaodan Yu
IPC分类号: C12P19/56
摘要: The present invention relates, at least in part, to the production of steviol glycoside rebaudioside I through the use of variant UGT enzymes having activity to transfer a glucosyl group from UDP-glucose to rebaudioside A to produce rebaudioside I.
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公开(公告)号:US20190048374A1
公开(公告)日:2019-02-14
申请号:US16032800
申请日:2018-07-11
申请人: Conagen, Inc.
发明人: Rui zhou , Xiaodan Yu , Steven Chen
摘要: The present invention relates to the production of eriodictyol via bioconversion.
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公开(公告)号:US10160781B2
公开(公告)日:2018-12-25
申请号:US15485309
申请日:2017-04-12
申请人: Conagen Inc.
发明人: Guohong Mao , Xiaodan Yu
IPC分类号: A23G3/00 , C12P19/56 , C12P19/00 , C12P21/06 , C12P19/34 , C12N9/00 , C12N9/10 , C07H21/04 , C07K1/00 , C07H15/24 , A23L2/60 , C07H15/256 , C07H1/00 , A23L27/30 , A23L33/10 , C12P19/18
摘要: Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside G (Reb G), rebaudioside KA (Reb KA), rebaudioside V (Reb V) and rebaudioside (Reb W).
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