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101 条记录 (耗时 0.04 秒)

    Nucleic acids and polypeptides of C1 bacteriophage and uses thereof
    22.
    发明授权
    Nucleic acids and polypeptides of C1 bacteriophage and uses thereof 有权
    C1噬菌体的核酸和多肽及其用途

    公开(公告)号：US07838255B2

    公开(公告)日：2010-11-23

    申请号：US12460746

    申请日：2009-07-23

    申请人： Vincent Fischetti ,  Daniel Nelson ,  Raymond Schuch

    发明人： Vincent Fischetti ,  Daniel Nelson ,  Raymond Schuch

    IPC分类号： G01N33/53 ,  A61L2/00

    CPC分类号： C12N9/503

    摘要： The full-length nucleic acid sequence of the C1 bacteriophage is disclosed in the present application. The specific regions of the C1 genome encoding the PlyC lysin have also been identified and sequenced. The invention relates to the pharmaceutical and diagnostic utility of these sequences and provides for development of pharmaceutical compositions for treating or preventing streptococcal infections in mammals, for compositions for decontamination of inanimate surfaces and for diagnosis of streptococcal infections.

    摘要翻译： C1噬菌体的全长核酸序列在本申请中公开。 编码PlyC溶素的C1基因组的特定区域也已被鉴定并测序。 本发明涉及这些序列的药物和诊断实用性，并且提供用于治疗或预防哺乳动物中链球菌感染的药物组合物的开发，用于无生物表面净化的组合物和用于诊断链球菌感染的组合物。

    Methods and apparatus for using location information to manage spillover in an audience monitoring system
    23.
    发明授权
    Methods and apparatus for using location information to manage spillover in an audience monitoring system 有权
    使用位置信息管理观众监控系统溢出的方法和设备

    公开(公告)号：US07739705B2

    公开(公告)日：2010-06-15

    申请号：US11692087

    申请日：2007-03-27

    申请人： Morris Lee ,  Daniel Nelson ,  Weston Headley

    发明人： Morris Lee ,  Daniel Nelson ,  Weston Headley

    IPC分类号： H04H60/33 ,  H04H60/32

    CPC分类号： H04N21/43615 ,  G08C2201/91 ,  H04H60/31 ,  H04H60/52 ,  H04H2201/90 ,  H04N7/16 ,  H04N21/25866 ,  H04N21/4126 ,  H04N21/4131 ,  H04N21/44213 ,  H04N21/44218 ,  H04N21/44222 ,  H04N21/6582 ,  H04N21/8352

    摘要： Methods, apparatus, and articles of manufacture for using location information to manage spillover in an audience monitoring system are disclosed. In particular, the example methods, apparatus, and articles of manufacture detect spillover to generate media monitoring information. Initially, a first sensor located in a first location and a second sensor located in a second location receive a portable metering device signal. First location information is associated with receiving the portable metering device signal via the first sensor and second location information is associated with receiving the portable metering device signal via the second sensor. Media monitoring information is generated based on one of the first location information or the second location information.

    摘要翻译： 公开了使用位置信息来管理观众监视系统中的溢出的方法，装置和制品。 特别地，示例性方法，装置和制品检测溢出以产生媒体监视信息。 最初，位于第一位置的第一传感器和位于第二位置的第二传感器接收便携式计量装置信号。 第一位置信息与经由第一传感器接收便携式计量装置信号相关联，并且第二位置信息与经由第二传感器接收便携式计量装置信号相关联。 基于第一位置信息或第二位置信息之一生成介质监视信息。

    BACTERIOPHAGE LYSINS FOR BACILLUS ANTHRACIS
    24.
    发明申请
    BACTERIOPHAGE LYSINS FOR BACILLUS ANTHRACIS 有权
    BACILLIOPHAGE LYSINS为BACILLUS ANTHRACIS

    公开(公告)号：US20100120673A1

    公开(公告)日：2010-05-13

    申请号：US11916208

    申请日：2006-05-31

    申请人： Pauline Yoong ,  Raymond Schuch ,  Daniel Nelson ,  Vincent A. Fischetti

    发明人： Pauline Yoong ,  Raymond Schuch ,  Daniel Nelson ,  Vincent A. Fischetti

    IPC分类号： A61K38/16 ,  C07K14/32 ,  A61P31/04

    CPC分类号： C12N9/503 ,  A61K38/00

    摘要： The present disclosure relates to methods, compositions and articles of manufacture useful for the treatment of Bacillus anthracis and S. cereus bacteria and spores, and related conditions. The disclosure further relates to compositions comprising various phage associated lytic enzyme that rapidly and specifically detect and kill Bacillus anthracis and other bacteria. Related articles of manufacture, methods of degrading spores and methods of treatment of infections or bacteria populations of, or subjects exposed to or at risk for exposure to Bacillus anthracis are also provided.

    摘要翻译： 本公开涉及可用于治疗炭疽芽孢杆菌和蜡状芽孢杆菌和孢子的方法，组合物和制品以及相关条件。 本公开还涉及包含各种噬菌体相关裂解酶的组合物，其快速且特异性地检测和杀死炭疽杆菌和其他细菌。 还提供了相关的制造方法，降低孢子的方法和处理暴露于或有暴露于炭疽芽孢杆菌的风险的感染或细菌群体或受试者的方法。

    Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
    25.
    发明授权
    Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions 有权
    用于治疗肺炎链球菌的噬菌体相关裂解酶及相关条件

    公开(公告)号：US07569223B2

    公开(公告)日：2009-08-04

    申请号：US10869751

    申请日：2004-06-16

    申请人： Vincent A. Fischetti ,  Jutta M. Loeffler ,  Daniel Nelson

    发明人： Vincent A. Fischetti ,  Jutta M. Loeffler ,  Daniel Nelson

    IPC分类号： A61K38/46 ,  A61K38/48

    CPC分类号： A61K38/47 ,  A61K38/162 ,  C12Q1/18 ,  C12Y302/01017 ,  G01N2333/3156 ,  A61K2300/00

    摘要： The present disclosure relates to methods, compositions and articles of manufacture useful for the treatment of Streptococcus pneumonia bacteria and spores, and related conditions. The disclosure further relates to methods and compositions for the identification of a phage associated lytic enzyme to rapidly kill Streptococcus pneumoniae and other bacteria. Related articles of manufacture, methods of degrading spores and methods of treatment of infections or bacteria populations of, or subjects exposed to or at risk for exposure to, Streptococcus pneumoniae are also provided.

    摘要翻译： 本公开涉及可用于治疗肺炎链球菌和孢子的方法，组合物和制品以及相关条件。 本公开还涉及用于鉴定噬菌体相关裂解酶以快速杀死肺炎链球菌和其他细菌的方法和组合物。 还提供了相关制造方法，降低孢子的方法和治疗感染或细菌群体或暴露于或有暴露于肺炎链球菌风险的受试者的方法。

    FREE END BAND AND SEAL
    26.
    发明申请
    FREE END BAND AND SEAL 有权
    免费终端和密封

    公开(公告)号：US20060272133A1

    公开(公告)日：2006-12-07

    申请号：US11422854

    申请日：2006-06-07

    申请人： Douglas Ingalls ,  Bai Tran ,  Dan Grant ,  Brian Swetlic ,  Mark Mossbrucker ,  Daniel Nelson ,  Rene Leist

    发明人： Douglas Ingalls ,  Bai Tran ,  Dan Grant ,  Brian Swetlic ,  Mark Mossbrucker ,  Daniel Nelson ,  Rene Leist

    IPC分类号： B65D63/02

    CPC分类号： B65D63/06 ,  Y10T24/1457 ,  Y10T24/1465 ,  Y10T24/49

    摘要： A pre-cut and preformed free end band and seal of a predetermined length, and method of making and using the same is disclosed. The band is preformed with a substantially closed loop of band material to capture a seal to provide a preassembled band and seal wherein the seal is generally inhibited from being dislodged during packing, shipment, handling and installation. The band and seal are also formed in a manner to facilitate relative positioning of the band and seal as well as placement of a crimping tool relative to the band and seal for optimized crimping of the band and seal.

    摘要翻译： 公开了一种预切割和预制的预定长度的自由端带和密封件，以及制造和使用它们的方法。 该带用基本封闭的带状材料环制成，以捕获密封件以提供预先组装的带和密封，其中密封通常在包装，装运，处理和安装期间被禁止移出。 带和密封件还以便于带和密封件的相对定位以及压接工具相对于带和密封件放置的方式形成，以优化带和密封的卷曲。

    Blank capable of forming a container having an integral pour spout
    29.
    发明申请
    Blank capable of forming a container having an integral pour spout 审中-公开
    能够形成具有整体倾倒口的容器的空白

    公开(公告)号：US20050274782A1

    公开(公告)日：2005-12-15

    申请号：US10865559

    申请日：2004-06-10

    申请人： J. Petrelli ,  Daniel Nelson

    发明人： J. Petrelli ,  Daniel Nelson

    IPC分类号： B65D5/72 ,  B65D5/74

    CPC分类号： B65D5/745

    摘要： A packaging blank capable of forming a reclosable container comprises in one embodiment a front panel having opposing side panels, a rear panel connected to the front panel by the second side panel, a top panel connected to a top edge of the front panel, a bottom panel connected to a bottom edge of the front panel, and a pour spout flap connected to a top edge of the second side panel. Upon construction the packaging blank provides a reclosable container having an integral pour spout that is releasably securable to a portion of the top panel. Still further, the invention relates to a method of forming the container and a method of packaging articles in the container.

    摘要翻译： 能够形成可再闭合容器的包装坯料在一个实施例中包括具有相对侧板的前面板，通过第二侧板连接到前面板的后面板，连接到前面板顶部边缘的顶板，底板 面板连接到前面板的底部边缘，以及连接到第二侧面板的顶部边缘的倒出口。 在构造时，包装坯料提供可再封闭的容器，其具有可释放地固定到顶板的一部分的整体倾倒口。 此外，本发明涉及一种形成容器的方法以及将物品包装在容器中的方法。

    Candle with central core and stacked rings
    30.
    发明申请
    Candle with central core and stacked rings 审中-公开
    蜡烛与中央核心和堆叠环

    公开(公告)号：US20050214704A1

    公开(公告)日：2005-09-29

    申请号：US10808019

    申请日：2004-03-23

    申请人： George Pappas ,  Daniel Nelson

    发明人： George Pappas ,  Daniel Nelson

    IPC分类号： F23D3/16 ,  F23D3/18

    CPC分类号： F23D3/16

    摘要： A candle having a central axial core of candle fuel, preferably wax, a wick extending axially within the central core and a plurality of stacked rings disposed around the central core. The rings may be made of differing compositions, including differing coloring agents and scenting agents and preferably are slidable along the core so they are interchangeable.

    摘要翻译： 蜡烛，其具有蜡烛燃料的中心轴向芯，优选蜡，在中心芯内轴向延伸的芯和围绕中心芯设置的多个堆叠环。 环可以由不同的组合物制成，包括不同的着色剂和香味剂，并且优选地可以沿核心滑动，使得它们是可互换的。