CATHETER WITH A POLYMIDE DISTAL TIP
    21.
    发明申请
    CATHETER WITH A POLYMIDE DISTAL TIP 有权
    带有聚合物的导管

    公开(公告)号:US20120083732A1

    公开(公告)日:2012-04-05

    申请号:US13323008

    申请日:2011-12-12

    Abstract: A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.

    Abstract translation: 一种具有细长轴的导管,该细长轴具有由聚酰亚胺第一材料形成的第一层和由聚合物第二材料形成的第二层的多层远端。 在一个实施例中,多层远侧末端是远离轴的近端部分的远端的分离的构件。 在另一个实施例中,轴具有外部管状构件和多层内部管状构件,其具有形成轴的多层远侧末端的远端。 在目前优选的实施方案中,聚酰亚胺材料是热固性聚酰亚胺。 在一个实施方案中,聚合物第二材料是聚酰胺材料。

    PROCESS FOR TUMOUR CHARACTERISTIC AND MARKER SET IDENTIFICATION, TUMOUR CLASSIFICATION AND MARKER SETS FOR CANCER
    22.
    发明申请
    PROCESS FOR TUMOUR CHARACTERISTIC AND MARKER SET IDENTIFICATION, TUMOUR CLASSIFICATION AND MARKER SETS FOR CANCER 审中-公开
    肿瘤特征和标记物识别,肿瘤分类和肿瘤标志物的方法

    公开(公告)号:US20120040863A1

    公开(公告)日:2012-02-16

    申请号:US13263426

    申请日:2010-04-16

    Abstract: A process to identify tumour characteristics involves obtaining three different marker sets each predictive of a characteristic of interest, obtaining a sample gene expression signals from tumour cells, adding a reporter to affect a change in the sample permitting assessment of a gene expression signal of interest in the tumour, combining the gene expression signals with the reporter, correlating the extracted gene expression signals to the three different marker sets, assigning a designation to the extracted gene expression signals according to the following rankings: if the correlation of all three predictive gene expression signal sets predict it to have characteristics of concern, it is designated a bad tumour; if the correlation of all three predictive gene expression signal sets predict it to lack characteristics of concern it is designated a good tumour; and, if the correlation of all three predictive gene expression signal sets do not provide the same predicted clinical outcome, the tumour is designated as “intermediate”; and, outputting said designation.

    Abstract translation: 识别肿瘤特征的过程涉及获得三种不同的标志物组,每种标记组各自预期感兴趣的特征,获得来自肿瘤细胞的样品基因表达信号,加入报告物以影响样品中的变化,允许评估感兴趣的基因表达信号 肿瘤,将基因表达信号与报告基因组合,将提取的基因表达信号与三种不同的标记组相关联,根据以下等级指定提取的基因表达信号:如果所有三种预测基因表达信号的相关性 集合预测它具有关注的特征,被指定为不良肿瘤; 如果所有三种预测基因表达信号组的相关性预测它缺乏关注的特征,则被指定为良好的肿瘤; 如果所有三种预测基因表达信号组的相关性不能提供相同的预测临床结果,则将肿瘤命名为“中间”; 并输出所述指定。

    Catheter with a multilayered shaft section having a polyimide layer
    23.
    发明授权
    Catheter with a multilayered shaft section having a polyimide layer 有权
    具有具有聚酰亚胺层的多层轴部的导管

    公开(公告)号:US07556634B2

    公开(公告)日:2009-07-07

    申请号:US11038971

    申请日:2005-01-18

    Abstract: A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.

    Abstract translation: 一种具有多层轴部的导管,其具有由聚酰亚胺第一材料形成的第一层和由第二材料形成的第二层。 在目前优选的实施方案中,聚酰亚胺材料是热固性聚酰亚胺。 然而,在替代实施例中,使用热塑性聚酰亚胺。 热固性聚酰亚胺具有约400℃的非常高的玻璃化转变温度(Tg)(通过差示扫描量热法测量),以及在导管组件中常用的聚酰胺的加工温度下的优异的尺寸稳定性。 结果,在导管的形成和组装过程中,有助于生产具有受控尺寸的薄聚酰亚胺层。 聚酰亚胺具有高模量并且提供薄壁且高度可推动的轴部分,而第二层提供扭结阻力。 在一个实施方案中,第二材料选自聚酰胺材料和聚氨酯材料。

    Catheter balloon having impregnated balloon skirt sections
    25.
    发明申请
    Catheter balloon having impregnated balloon skirt sections 有权
    导管球囊已浸渍气囊裙部

    公开(公告)号:US20070038240A1

    公开(公告)日:2007-02-15

    申请号:US11585071

    申请日:2006-10-23

    Abstract: A balloon catheter and a method of making a balloon catheter, having a balloon with a first layer and a second layer, the first layer having at least one impregnated section impregnated with a polymeric material compatible with a polymeric material forming the catheter shaft. At least a portion of the impregnated section is fusion bonded to the shaft. In a presently preferred embodiment, the impregnated section is adjacent to a section of the first layer which is not impregnated with the compatible polymeric material. The impregnated section provides improved bonding of the balloon to the catheter shaft while minimizing the effect of the bond on catheter performance characteristics such as profile and flexibility.

    Abstract translation: 气囊导管和制造球囊导管的方法,具有具有第一层和第二层的气囊,所述第一层具有浸渍有与形成导管轴的聚合物材料相容的聚合材料的至少一个浸渍部分。 浸渍部分的至少一部分熔合在轴上。 在目前优选的实施方案中,浸渍的部分邻近第一层的不被相容的聚合物材料浸渍的部分。 浸渍部分提供了球囊与导管轴的改善的粘合,同时最小化粘合对导管性能特征如轮廓和柔性的影响。

    Header compress/decompress framework
    28.
    发明授权
    Header compress/decompress framework 有权
    标题压缩/解压缩框架

    公开(公告)号:US07773632B2

    公开(公告)日:2010-08-10

    申请号:US10582528

    申请日:2005-12-08

    CPC classification number: H04L69/04 H04L69/22

    Abstract: Machine-readable media, methods, and apparatus are described. In some embodiments, a header policy for a packet to be transmitted through the network is defined based upon characteristics of the network and a header of the packet is compressed based upon whether the header policy indicates the header of the packet is to be compressed.

    Abstract translation: 描述了机器可读介质,方法和装置。 在一些实施例中,基于网络的特性来定义要通过网络发送的分组的报头策略,并且基于报头策略是否要对分组的报头进行压缩来压缩分组的报头。

    CATHETER WITH A MULTILAYERED SHAFT SECTION HAVING A POLYIMIDE LAYER
    29.
    发明申请
    CATHETER WITH A MULTILAYERED SHAFT SECTION HAVING A POLYIMIDE LAYER 有权
    具有聚酰亚胺层的多层轴的导管

    公开(公告)号:US20090247946A1

    公开(公告)日:2009-10-01

    申请号:US12477695

    申请日:2009-06-03

    Abstract: A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.

    Abstract translation: 一种具有多层轴部的导管,其具有由聚酰亚胺第一材料形成的第一层和由第二材料形成的第二层。 在目前优选的实施方案中,聚酰亚胺材料是热固性聚酰亚胺。 然而,在替代实施例中,使用热塑性聚酰亚胺。 热固性聚酰亚胺具有约400℃的非常高的玻璃化转变温度(Tg)(通过差示扫描量热法测量),以及在导管组件中常用的聚酰胺的加工温度下的优异的尺寸稳定性。 结果,在导管的形成和组装过程中,有助于生产具有受控尺寸的薄聚酰亚胺层。 聚酰亚胺具有高模量并且提供薄壁且高度可推动的轴部分,而第二层提供扭结阻力。 在一个实施方案中,第二材料选自聚酰胺材料和聚氨酯材料。

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