-
公开(公告)号:US10386623B2
公开(公告)日:2019-08-20
申请号:US15697702
申请日:2017-09-07
申请人: Inscopix, Inc.
发明人: Koen Visscher , Shung Chieh , Arash Tajik
IPC分类号: G02B21/00 , G02B21/06 , G02B21/18 , A61B5/00 , G01N1/44 , H04N5/232 , G06T11/00 , G06T7/38 , G06T7/32 , G06T3/00 , G02B21/36 , A61B1/00 , G06T7/33
摘要: Disclosed herein are adapters configured to be optically coupled to a plurality of microscopes, said adapter comprising: a) a first microscope interface configured to optically couple a first microscope to an optical element in optical communication with an optical probe; b) a second microscope interface configured to optically couple a second microscope to the optical element in optical communication with the optical probe; and c) an optical arrangement configured to direct light collected from a sample with aid of the optical probe to (1) the first microscope and second microscope simultaneously, or (2) the first microscope or second microscope selectively.
-
公开(公告)号:US12099175B2
公开(公告)日:2024-09-24
申请号:US17104157
申请日:2020-11-25
申请人: Inscopix, Inc.
发明人: Koen Visscher , Shung Chieh , Arash Tajik
IPC分类号: G02B21/18 , A61B1/00 , A61B5/00 , G01N1/44 , G02B21/36 , G06T3/153 , G06T7/32 , G06T7/33 , G06T7/38 , G06T11/00 , H04N23/67
CPC分类号: G02B21/18 , A61B1/00186 , A61B5/0064 , A61B5/0068 , A61B5/0084 , G01N1/44 , G02B21/362 , G02B21/367 , G06T3/153 , G06T7/32 , G06T7/33 , G06T7/38 , G06T11/003 , H04N23/67 , A61B5/0071 , G06T2207/10016 , G06T2207/10056 , G06T2207/20024 , G06T2207/20056
摘要: An adapter configured to be optically coupled to a plurality of microscopes and including a) a first microscope interface configured to optically couple a first microscope to an optical element in optical communication with an optical probe; b) a second microscope interface configured to optically couple a second microscope to the optical element in optical communication with the optical probe; and c) an optical arrangement configured to direct light collected from a sample with the aid of the optical probe to (1) the first microscope and second microscope simultaneously, or (2) the first microscope or second microscope selectively.
-
公开(公告)号:US20240115344A1
公开(公告)日:2024-04-11
申请号:US18543190
申请日:2023-12-18
申请人: Inscopix, Inc.
发明人: Koen VISSCHER , Pei Sabrina XU , Shay NEUFELD
IPC分类号: A61B90/20 , A61B5/00 , G01N21/64 , G02B21/00 , G02B21/02 , G02B21/06 , G02B21/16 , G02B21/32
CPC分类号: A61B90/20 , A61B5/0059 , A61B5/0071 , A61B5/4064 , G01N21/6458 , G02B21/0004 , G02B21/0096 , G02B21/025 , G02B21/06 , G02B21/16 , G02B21/32 , G02B3/14
摘要: An adapter configured to be optically coupled to a plurality of microscopes and having (i) a first microscope interface configured to optically couple a first microscope system to an optical element that is in optical communication with an optical probe to provide first imaging data of a sample, and (ii) a second microscope interface configured to optically couple a second microscope system to the optical element to provide second imaging data of the sample. An optical imaging apparatus and method utilizing such adapter.
-
公开(公告)号:US20230285107A1
公开(公告)日:2023-09-14
申请号:US18198486
申请日:2023-05-17
申请人: Inscopix, Inc.
发明人: Mark O. TRULSON , Alice STAMATAKIS , Koen VISSCHER
IPC分类号: A61B90/20 , G01N21/64 , G02B21/16 , G02B21/06 , A61B5/00 , G02B21/02 , G02B21/00 , G02B21/32
CPC分类号: A61B90/20 , G01N21/6458 , G02B21/16 , G02B21/06 , A61B5/0071 , G02B21/025 , A61B5/0059 , A61B5/4064 , G02B21/0004 , G02B21/0096 , G02B21/32 , G02B3/14
摘要: Systems and methods configured for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.
-
公开(公告)号:US11595622B2
公开(公告)日:2023-02-28
申请号:US17316394
申请日:2021-05-10
申请人: Inscopix, Inc.
发明人: Kunal Ghosh
摘要: System and methods are provided for distributed microscopy. A plurality of microscopes may capture images and send them to a media server. The microscopes and the media server may be part of a local area network. The microscopes may each have a distinct network address. The media server may communicate with an operations console, which may be used to view images captured by the microscopes. The operations console may also accept user input which may be used to selectively control the microscopes.
-
公开(公告)号:US20210247603A1
公开(公告)日:2021-08-12
申请号:US17121841
申请日:2020-12-15
申请人: Inscopix, Inc.
发明人: Mark TRULSON , Koen VISSCHER , Kevin E. NEWMAN
摘要: Provided herein are systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope system can comprise various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
-
公开(公告)号:US10908405B2
公开(公告)日:2021-02-02
申请号:US15256296
申请日:2016-09-02
申请人: Inscopix, Inc.
发明人: Mark Trulson , Koen Visscher , Kevin E. Newman
摘要: Provided herein are systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope system can comprise various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
-
公开(公告)号:US20150309295A1
公开(公告)日:2015-10-29
申请号:US14440026
申请日:2013-11-05
申请人: INSCOPIX, INC.
发明人: Eric COCKER , Kunal GHOSH
CPC分类号: G02B21/0076 , A61B5/0042 , A61B5/0071 , A61B5/4064 , G02B21/06 , G02B21/362 , G03B15/00 , G03B17/02 , G03B17/561
摘要: The invention provides miniaturized devices, systems and methods for imaging of biological specimens. The devices and system provide accurate alignment and modular mounting of imaging components internally and in relation to the target subject. In some embodiments, the invention provides devices, systems and methods for in vivo fluorescent brain imaging in freely-behaving rodents.
摘要翻译: 本发明提供了用于生物标本成像的小型化装置,系统和方法。 设备和系统在内部和与目标物体相关的位置提供精确的对准和成像部件的模块化安装。 在一些实施方案中,本发明提供了用于自由行为的啮齿动物体内荧光脑成像的装置,系统和方法。
-
公开(公告)号:US20130260382A1
公开(公告)日:2013-10-03
申请号:US13767814
申请日:2013-02-14
申请人: INSCOPIX, INC.
发明人: Kunal Ghosh , Eric Cocker , Mark J. Schnitzer
IPC分类号: G01N21/64
CPC分类号: G01N21/6486 , G02B21/33 , G02B27/02
摘要: Systems and methods are provided for imaging a sample. A portable slide reader may be provided that may be configured to accept a slide and that may contain one or more miniature microscopes therein. The slide reader may include a display showing images captured by the microscopes. The slide may be movable relative to the microscopes and the position of the captured image may be controllable. In some instances, images captured may be useful for DNA sequencing. Multiple color ranges may be captured for a target region, corresponding to different nucleobases.
摘要翻译: 为样品成像提供了系统和方法。 可以提供可以被配置为接受幻灯片并且可以在其中容纳一个或多个微型显微镜的便携式幻灯片阅读器。 幻灯片读取器可以包括显示由显微镜捕获的图像的显示器。 滑块可以相对于显微镜可移动,并且捕获的图像的位置可以是可控的。 在某些情况下,捕获的图像可能对DNA测序有用。 可以针对对应于不同核碱基的靶区域捕获多个颜色范围。
-
公开(公告)号:US11733501B2
公开(公告)日:2023-08-22
申请号:US17121841
申请日:2020-12-15
申请人: Inscopix, Inc.
发明人: Mark Trulson , Koen Visscher , Kevin E. Newman
CPC分类号: G02B21/18 , G02B19/0014 , G02B19/0066 , G02B21/02 , G02B21/241 , G02B21/361 , G02B21/367 , G02B27/0037
摘要: Provided herein are systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope system can comprise various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
-
-
-
-
-
-
-
-
-