公开(公告)号：US08509905B2

公开(公告)日：2013-08-13

申请号：US13447026

申请日：2012-04-13

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/18

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

公开(公告)号：US08423147B2

公开(公告)日：2013-04-16

申请号：US13245500

申请日：2011-09-26

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  James R. Thacker

IPC: A61N1/372

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal chord region to address low back pain without creating unwanted sensory and/or motor side affects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications. In particular embodiments, aspects of the foregoing modulation therapies may be implemented by systems and devices that have simplified functionalities.

Abstract translation: 在特定实施例中，可以将约1.5KHz至约50KHz范围内的高频调制施加到患者的脊弦区域以解决腰背痛而不产生不想要的感觉和/或运动副作用。 在其他实施例中，根据类似参数的调制可以应用于其他脊柱或周边位置以解决其他指示。 在具体实施例中，前述调制疗法的方面可以由具有简化功能的系统和设备来实现。

公开(公告)号：US20130066411A1

公开(公告)日：2013-03-14

申请号：US13607617

申请日：2012-09-07

Applicant: James R. Thacker ,  Konstantinos Alataris ,  Bradford Evan Gliner

Inventor： James R. Thacker ,  Konstantinos Alataris ,  Bradford Evan Gliner

IPC: A61N1/05

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/06 ,  A61N1/36075 ,  A61N1/36157 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36185

Abstract: Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region from an epidural, cervical location to address at least one of high back pain, mid-back pain, low back pain, and leg pain without creating paresthesia in the patient.

Abstract translation: 公开了选择性高频脊髓调制，用于抑制疼痛，减少副作用和相关系统和方法。 在特定实施例中，可以从硬膜外，颈部位置向大约1.5KHz至大约50KHz范围内的高频调制施加到患者的脊髓区域，以解决高背痛，中背痛， 腰痛和腿部疼痛，而不会在患者身上产生感觉异常。

公开(公告)号：US08359103B2

公开(公告)日：2013-01-22

申请号：US13446992

申请日：2012-04-13

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/18

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

公开(公告)号：US08355792B2

公开(公告)日：2013-01-15

申请号：US13446944

申请日：2012-04-13

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/18

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

公开(公告)号：US20120203304A1

公开(公告)日：2012-08-09

申请号：US13447026

申请日：2012-04-13

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/34

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal chord region to address low back pain without creating unwanted sensory and/or motor side affects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

公开(公告)号：US08233991B2

公开(公告)日：2012-07-31

申请号：US11105643

申请日：2005-04-13

Applicant: Carla M. Woods ,  James R. Thacker ,  David K. Peterson ,  Holly A. Segel ,  Susan E. Ford ,  Margaret E. Theriot ,  Kerry Bradley

Inventor： Carla M. Woods ,  James R. Thacker ,  David K. Peterson ,  Holly A. Segel ,  Susan E. Ford ,  Margaret E. Theriot ,  Kerry Bradley

IPC: A61N1/04

CPC classification number: A61N1/36071 ,  A61N1/08 ,  A61N1/36185 ,  A61N1/37241 ,  A61N1/37247

Abstract: Methods for selecting Spinal Cord Stimulation (SCS), or other medical electrical stimulator, electrode configurations from a set of electrode configurations are provided. Each electrode configuration represents a polarity or a polarity percentage of the electrodes of an electrode array. The selected electrode configurations may be used in a medical electrical stimulator. Such methods of selecting electrode configurations results in a more efficient programming and use of the stimulation system.

Abstract translation: 提供了从一组电极配置中选择脊髓刺激（SCS）或其他医疗电刺激器电极配置的方法。 每个电极配置表示电极阵列的电极的极性或极性百分比。 所选择的电极配置可以用在医疗电刺激器中。 这种选择电极配置的方法导致更有效的编程和使用刺激系统。

公开(公告)号：US20110190847A1

公开(公告)日：2011-08-04

申请号：US13069143

申请日：2011-03-22

Applicant: John D.H. King ,  James R. Thacker

Inventor： John D.H. King ,  James R. Thacker

IPC: A61N1/36

CPC classification number: A61N1/36139 ,  A61N1/08 ,  A61N1/36071 ,  A61N1/3615

Abstract: A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.

Abstract translation: 神经刺激系统自动校正或调整刺激量（刺激能量），以保持舒适有效的刺激疗法。 由于与电极 - 组织界面相关的阻抗变化可以指示电流和位置引线位移的阻塞，所以引线阻抗可以指示应该传送到目标神经组织的电刺激能量的量以提供校正调整。 因此，可以在反馈回路中使用阻抗曲线的阻抗或形态的变化，以指示需要调整刺激能量，并且系统能够有效地自动校正刺激能量的大小以维持所需的治疗效果。

公开(公告)号：US07801621B1

公开(公告)日：2010-09-21

申请号：US11742543

申请日：2007-04-30

Applicant: James R. Thacker ,  Carla Mann Woods

Inventor： James R. Thacker ,  Carla Mann Woods

IPC: A61N1/00

CPC classification number: A61B5/6885 ,  A61B5/03 ,  A61N1/08 ,  A61N1/36128

Abstract: A neural stimulation system automatically corrects or adjusts the stimulus magnitude in order to maintain a comfortable and effective stimulation therapy. Auto correction of the stimulus magnitude is linked to the measurement of pressure in the vicinity of the electrode-tissue interface. Because the pressure near the electrode-tissue interface can provide a measure of the electrode contacts' proximity to the neural tissue, and hence quantity of electrical energy delivered to the neural tissue, a change in the measured pressure or pressure morphology indicates that the stimulation energy may need to be adjusted. Hence, changes in pressure provide a feedback mechanism that permit the system to effectively auto correct the stimulus amplitude in order to maintain a desired therapeutic effect.

Abstract translation: 神经刺激系统自动校正或调整刺激量值，以保持舒适有效的刺激治疗。 刺激大小的自动校正与电极组织界面附近的压力测量有关。 因为电极 - 组织界面附近的压力可以提供电极接触靠近神经组织的量度，并且因此提供给神经组织的电能量，测量的压力或压力形态的变化表明刺激能量 可能需要调整。 因此，压力变化提供了一种反馈机制，其允许系统有效地自动校正刺激振幅，以便保持期望的治疗效果。

公开(公告)号：US20100010566A1

公开(公告)日：2010-01-14

申请号：US12501282

申请日：2009-07-10

Applicant: James R. Thacker ,  Michael Moffitt ,  Kerry Bradley ,  David K.L. Peterson

Inventor： James R. Thacker ,  Michael Moffitt ,  Kerry Bradley ,  David K.L. Peterson

IPC: A61N1/08 ,  A61N1/34

CPC classification number: A61N1/37264 ,  A61N1/36071 ,  A61N1/36146 ,  A61N1/3615 ,  A61N1/36167 ,  A61N1/36185 ,  A61N1/37247 ,  G06F19/00 ,  G16H40/63

Abstract: A method, computer medium, and system for programming a controller is provided. The controller controls electrical stimulation energy output to electrodes, and stores a set of programmed stimulation parameters associated with the electrodes. The programmed stimulation parameter set is compared with sets of reference stimulation parameters, each of the reference sets of stimulation parameters being associated with the electrodes. If an identical match is determined between the programmed stimulation parameter set and any one of the reference stimulation parameter sets exists based on the comparison, the identically matched stimulation parameter set is selected as an initial stimulation parameter set. If an identical match does not exist, a best between the programmed stimulation parameter set and the reference stimulation parameter sets is determined and selected as the initial stimulation parameter set. The controller is then programmed with a new set of programmable stimulation parameters based on the initial stimulation parameter set.

Abstract translation: 提供了一种用于编程控制器的方法，计算机介质和系统。 控制器控制对电极的电刺激能量输出，并且存储与电极相关联的一组编程的刺激参数。 将编程的刺激参数集与参考刺激参数的集合进行比较，每个参考组的刺激参数与电极相关联。 如果在编程的刺激参数集之间确定相同的匹配，并且基于比较存在参考刺激参数集中的任一个，则选择相同匹配的刺激参数集作为初始刺激参数集。 如果不存在相同的匹配，则确定编程的刺激参数集和参考刺激参数集之间的最佳值，并将其选为初始刺激参数集。 然后基于初始刺激参数集，控制器用一组新的可编程刺激参数进行编程。