Abstract:
A drug-delivery system is provided including at least 100 μg of everolimus and clobetasol, such that the ratio of everolimus to clobetasol is at least 10:1 (w/w) or the amount of everolimus by weight is at least 10 times more than clobetasol. The system can be a stent. Also provided a method of treating restenosis or vulnerable plaque of a blood vessel, the method includes locally administering to a patient a first drug selected from a group consisting of rapamycin (sirolimus), Biolimus A9, deforolimus, AP23572, tacrolimus, temsirolimus, pimecrolimus, zotarolimus (ABT-578), 40-O-(2-hydroxy)ethylrapamycin (everolimus), 40-O-(3-hydroxy)propylrapamycin, 40-O-[2-(2-hydroxy)ethoxy]ethylrapamycin, 40-O-tetrazolylrapamycin and 40-epi-(N1-tetrazolyl)rapamycin, and locally administering to a patient a second drug consisting of clobetasol, wherein the minimum amount of the first drug that is locally administered is 100 μg, and wherein the ratio of the first drug to the second drug is, for example, 10:1 to 100:1 (w/w).
Abstract:
The present invention is to provide a method for centrally distributing screensaver video to protect display devices, which is implemented to a central VOD system comprising a remote video server, a plurality of signal transmission devices, and display devices each connected to a signal transmission device. The remote video server has a plurality of ordinary video data and at least a screensaver video data therein; each signal transmission device may receive a screensaver video data and at least one ordinary video data, and then transmit the screensaver video data and the ordinary video data to the display device connected thereto. The signal transmission device outputs the screensaver data on the display device when not receiving any control signal within a predetermined period of time, and does not resume the original ordinary video data on the display device unless the signal transmission device receives the control signal again.
Abstract:
A method of dynamically showing a water mark is applied in an audio/video transmitter. The audio/video transmitter includes a plurality of display contents such as a playback area name, a playback date, a playback time and an identification mark. The audio/video transmitter continues obtaining a plurality of frames from an audio/video source such as an audio/video server or an audio/video database and temporarily stores the frames in a buffer. The audio/video transmitter also produces a water mark from at least one display content according to a plurality of display conditions such as display coordinates, appearance, time and frequency, and composes the water mark with at least one frame stored in the buffer to form at least one display screen, and shows the display screen on an output unit, such that the water mark on the display screen cannot be changed or overwritten, and viewers can identify the water mark easily.
Abstract:
An apparatus for delivering devices. The apparatus comprises a catheter with an elongated shaft having a first lumen and a second lumen extending therethrough. The apparatus further comprises a distal section with a lumen in communication with a port in a distal end of the catheter and with the first lumen and the second lumen. The first lumen is configured for a first device and the second lumen is configured for a second device to be disposed therein. The apparatus further comprises a proximal adapter coupled to the elongated shaft with a first port in communication with the first lumen and a second port in communication with the second lumen.
Abstract:
A device and method for converting a low voltage signal into a high voltage signal are provided, which can be implemented by using a low voltage CMOS manufacturing process to convert a low voltage signal of 0V to 1.5V into a high voltage signal of 2.5V to 1.25V. According to one preferred embodiment, PMOS transistors are employed to perform voltage level conversion and supply voltages of 1.25V and 2.5V are supplied to the PMOS transistors. During the conversion, no current path exists between the supply voltages thus effectively reducing static power consumption. In addition, the low level of the high voltage signal is outputted through the drain and source of the transistor so that the low level of the high voltage signal can be accurately defined and not affected by manufacturing parameters.
Abstract:
A clock circuit for supporting a plurality of memory module types is provided. The clock circuit is connected to a first type memory module slot, and a second type memory module slot. The clock circuit includes a clock generator for producing a clock signal and a clock buffer having doubly defined clock pins for outputting the first type memory clock signal or the second type memory clock signal. The clock buffer receives the clock signal and outputs a first type memory clock signal to the first type memory clock pin. The doubly defined clock pin is also capable of outputting a second type memory clock signal to the second type memory clock pin. This invention is capable of using just a single clock buffer to drive a plurality of different memory module types.
Abstract:
The present invention discloses a method of treating cancer in a subject. This involves co-administering a replicating virus and a matrix metalloproteinase to the subject under conditions effective to treat cancer. It also relates to a method of enhancing the delivery to and distribution within a tumor mass of therapeutic viruses. This involves co-administering a replicating virus and a matrix metalloproteinase to the tumor mass under conditions effective to enhance the delivery to and distribution within the tumor mass of therapeutic viruses. Another aspect relates to a cancer therapeutic. This involves a replicating virus and a matrix metalloproteinase.
Abstract:
A linear actuator with a quick-release mechanism allows the unpowered, loaded linear actuator to immediately return to its initial position by operating a rotatable involute cam of the quick-release mechanism. The quick-release mechanism is connected with a remote monitoring system so the current position of the linear actuator can be detected from a distant place.
Abstract:
A linear actuator with a quick-release mechanism allows the unpowered, loaded linear actuator to immediately return to its initial position by operating a rotatable involute cam of the quick-release mechanism. The quick-release mechanism is connected with a remote monitoring system so the current position of the linear actuator can be detected from a distant place.